Antitumor activities of emulsion electrospun fibers with core loading of hydroxycamptothecin via intratumoral implantation

International Journal of Pharmaceutics

Volumn 425, Issue 1-2, 2012, Pages 19-28

  Luo, Xiaoming ^a   Xie, Chengying ^a   Wang, Huan ^a   Liu, Chaoyu ^a   Yan, Shili ^a   Li, Xiaohong ^a  

^a SOUTHWEST JIAOTONG UNIVERSITY   (China)

Author keywords

Antitumor activity; Emulsion electrospinning; Intratumoral implantation; Release modulation; Structural integrity

Indexed keywords

2 HYDROXYPROPYL BETA CYCLODEXTRIN; ANTINEOPLASTIC AGENT; BUFFER; CASPASE 3; DRUG CARRIER; ELECTROSPUN FIBER; HYDROXYCAMPTOTHECIN; LACTONE; NANOFIBER; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BIODEGRADATION; CANCER CELL CULTURE; CANCER INHIBITION; CANCER SURVIVAL; CELL DEATH; CELL STRAIN HEPG2; CONTROLLED STUDY; CYTOTOXICITY; DRUG EFFICACY; DRUG RELEASE; ELECTROSPINNING; EMULSION; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SOLID TUMOR; SURVIVAL RATE; TUMOR VOLUME; WEIGHT CHANGE;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; BETA-CYCLODEXTRINS; CAMPTOTHECIN; CELL LINE, TUMOR; CELL SURVIVAL; DRUG CARRIERS; EMULSIONS; HUMANS; LACTATES; MICE; NEOPLASM TRANSPLANTATION; NEOPLASMS; POLYETHYLENE GLYCOLS; TUMOR BURDEN;

EID: 84862830100     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2012.01.012     Document Type: Article

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