Release pattern and structural integrity of lysozyme encapsulated in core-sheath structured poly(dl-lactide) ultrafine fibers prepared by emulsion electrospinning

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 69, Issue 1, 2008, Pages 106-116

  Yang, Ye ^a   Li, Xiaohong ^a   Qi, Mingbo ^a   Zhou, Shaobing ^a   Weng, Jie ^a  

^a SOUTHWEST JIAOTONG UNIVERSITY   (China)

Author keywords

Bioactivity; Burst release; Core shell structure; Emulsion electrospinning; In vitro release; Protein structures; Structural integrity; Ultrafine fibers

Indexed keywords

DODECYL SULFATE SODIUM; LYSOZYME; POLYLACTIDE;

ARTICLE; CHEMICAL PROCEDURES; DRUG RELEASE; ELECTRON MICROSCOPY; EMULSION; EMULSION ELECTROSPINNING; ENZYME DENATURATION; FIBER; GEL PERMEATION CHROMATOGRAPHY; LASER MICROSCOPY; MICROENCAPSULATION; POLYACRYLAMIDE GEL ELECTROPHORESIS; STRUCTURE ANALYSIS;

ANIMALS; BIOCOMPATIBLE MATERIALS; CHEMISTRY, PHARMACEUTICAL; DRUG CARRIERS; DRUG COMPOUNDING; ELECTROPHORESIS, POLYACRYLAMIDE GEL; KINETICS; MOLECULAR WEIGHT; MURAMIDASE; POLYESTERS; POLYMERS; POROSITY; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; TECHNOLOGY, PHARMACEUTICAL; TISSUE ENGINEERING;

EID: 41549159444     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejpb.2007.10.016     Document Type: Article

References (31)

1. Smith L.A., and Ma P.X. Nano-fibrous scaffolds for tissue engineering. Colloid Surf. B 39 (2004) 125-131
2. Cheng L., Zhang S.M., Chen P.P., Huang S.L., Liu L., Zhou W., Liu J., Gong H., and Luo Q.M. Fabrication and characterization of fluorohydroxyapatite nanocrystals/poly(d,l-lactide) composite scaffolds. Curr. Appl. Phys. 7 (2007) e71-e74
3. Murugan R., and Rammakrishna S. Nano-featured scaffolds for tissue engineering: a review of spinning methodologies. Tissue Eng. 12 (2006) 435-447
4. Li W.J., Laurencin C.T., Caterson E.J., Tuan R.S., and Ko F.K. Electrospun nanofibrous structure: a novel scaffold for tissue engineering. J. Biomed. Mater. Res. 60 (2002) 613-621
5. Goldberg M., Langer R., and Jia X. Nanostructured materials for applications in drug delivery and tissue engineering. J. Biomat. Sci. Polym. Ed. 18 (2007) 241-268
6. Kim K., Luu Y.K., Chang C., Fang D., Hsiao B.S., and Hadjiargyrou M. Incorporation and controlled release of a hydrophilic antibiotic using poly(lactide-co-glycolide)-based electrospun nanofibrous scaffolds. J. Control. Release 98 (2004) 47-56
7. Casper C.L., Yamaguchi N., Kiick K.L., and Rabolt J.F. Functionalizing electrospun fibers with biologically relevant macromolecules. Biomacromolecules 6 (2005) 1998-2007
8. Zeng J., Aigner A., Czubayko F., Kissel T., Wendorff J.H., and Greiner A. Poly(vinyl alcohol) nanofibers by electrospinning as a protein delivery system and the retardation of enzyme release by additional polymer coatings. Biomacromolecules 6 (2005) 1484-1488
9. Li C., Vepari C., Jin H.J., Kim H.J., and Kaplan D.L. Electrospun silk-BMP-2 scaffolds for bone tissue engineering. Biomaterials 27 (2006) 3115-3124
10. Kim T.G., Lee D.S., and Park T.G. Controlled protein release from electrospun biodegradable fiber mesh composed of poly(ε-caprolactone) and poly(ethylene oxide). Int. J. Pharm. 338 (2007) 276-283
11. Qi H., Hu P., Xu J., and Wang A. Encapsulation of drug reservoirs in fibers by emulsion electrospinning: morphology characterization and preliminary release assessment. Biomacromolecules 7 (2006) 2327-2330
12. Zhang Y.Z., Wang X., Feng Y., Li J., Lim C.T., and Ramakrishna S. Coaxial electrospinning of (fluorescein isothiocyanate-conjugated bovine serum albumin)-encapsulated poly (ε-caprolactone) nanofibers for sustained release. Biomacromolecules 7 (2006) 1049-1057
13. Jiang H., Hu Y., and Zhao P. Modulation of protein release from biodegradable core-shell structured fibers prepared by coaxial electrospinning. J. Biomed. Mater. Res. 79A (2006) 50-57
14. Xu X., Zhuang X., and Chen X. Preparation of core-sheath composite nanofibers by emulsion electrospinning. Macromol. Rapid Commun. 27 (2006) 1637-1642
15. Xu X., Yang L., and Chen X. Ultrafine medicated fibers electrospun from W/O emulsions. J. Control. Release 108 (2005) 33-42
16. Deng X.M., Yuan M.L., Xiong C.D., and Li X.H. Polymerization of lactides and lactones. 2: Ring -opening polymerization of e-caprolactone and dl-lactide by organoacid rare earth compounds. J. Appl. Polym. Sci. 71 (1999) 1941-1948
17. Cui W.G., Li X.H., Zhu X.L., Yu G., Zhou S.B., and Weng J. Investigation of drug release and matrix degradation of electrospun poly(dl-lactide) fibers with paracetanol inoculation. Biomacromolecules 7 (2006) 1623-1629
18. Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72 (1976) 248-254
19. Rafati H., Coombes A.G.A., Adler J., Holland J., and Davis S.S. Protein-loaded poly(dl-lactide-co-glycolide) microparticles for oral administration: formulation, structural and release characteristics. J. Control. Release 43 (1997) 89-102
20. Susi H., and Byler D.M. Protein structure by Fourier transform infrared spectroscopy: second derivative spectra. Biochem. Biophys. Res. 115 (1983) 391-397
21. Perez C., Jesus P.D., and Griebenow K. Preservation of lysozyme structure and function upon encapsulation and release from poly(lactic-co-glycolic) acid microspheres prepared by the water-in-oil-in-water method. Int. J. Pharm. 248 (2002) 193-206
22. Fu K., Griebenow K., and Hsieh L. FTIR characterization of the secondary structure of proteins encapsulated within PLGA microspheres. J. Control. Release 58 (1999) 357-366
23. Meng F.T., Ma G.H., Qiu W., and Su Z.G. W/O/W double emulsion technique using ethyl acetate as organ ic solvent: effects of its diffusion rate on the characteristics of microparticles. J. Control. Release 91 (2003) 407-416
24. Yu J.H., Fridrikh S.V., and Rutledge G.C. Production of submicrometer diameter fibers by two-fluid electrospinning. Adv. Mater. 16 (2004) 1562-1566
25. Haris P.I., and Chapman D. Does Fourier-transform infrared spectroscopy provide useful information on protein structures?. Trends Biochem. Sci. 17 (1992) 328-333
26. Poetsch A., Rexroth S., Heberle J., Link T.A., Dencher N.A., and Seelert H. Characterisation of subunit III and its oligomer from spinach chloroplast ATP synthase. Biochim. Biophys. Acta 1618 (2003) 59-66
27. Parvez I.H., and Feride S. FTIR spectroscopic characterization of protein structure in aqueous and non-aqueous media. J. Mol. Catal. B Enzym. 7 (1999) 207-221
28. Jonathan Hadden M., Chapman D., and Lee D.C. A comparison of infrared spectra of proteins in solution and crystalline forms. Biochim. Biophys. Acta 1248 (1995) 115-122
29. Byler D.M., and Susi H. Examination of the secondary structure of proteins by deconvolved FTIR spectra. Biopolymers 25 (1986) 469-487
30. Querol E., Perez-Pons J.A., and Mozo-Villarias A. Analysis of protein conformational characteristics related to thermostability. Protein Eng. 9 (1996) 265-271
31. Zhou S.B., Deng X.M., and Li X.H. Investigation on a novel core-coated microspheres protein delivery system. J. Control. Release 75 (2001) 27-36