Superior antitumor efficiency of cisplatin-loaded nanoparticles by intratumoral delivery with decreased tumor metabolism rate

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 70, Issue 3, 2008, Pages 726-734

  Li, Xiaolin ^a,b   Li, Rutian ^c   Qian, Xiaoping ^a,c   Ding, Yitao ^a,c   Tu, Yunxia ^c   Guo, Rui ^b   Hu, Yong ^b   Jiang, Xiqun ^b   Guo, Wanhua ^a   Liu, Baorui ^a,c  

^a THE AFFILIATED DRUM TOWER HOSPITAL OF NANJING UNIVERSITY MEDICAL SCHOOL   (China)

^b NANJING UNIVERSITY   (China)

^c MEDICAL SCHOOL OF NANJING UNIVERSITY   (China)

Author keywords

Antitumor; Cisplatin; Drug delivery; Nanoparticles; PET CT

Indexed keywords

CISPLATIN; FLUORODEOXYGLUCOSE F 18; MACROGOL; METHOXYPOLY(ETHYLENE GLYCOL); NANOPARTICLE; POLYCAPROLACTONE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CYTOTOXICITY; DRUG DELIVERY SYSTEM; DRUG RELEASE; HUMAN; HUMAN CELL; MALE; MOUSE; NANOENCAPSULATION; NANOFABRICATION; NONHUMAN; TUMOR GROWTH;

ANIMALS; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL SURVIVAL; CHEMISTRY, PHARMACEUTICAL; CISPLATIN; DELAYED-ACTION PREPARATIONS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG CARRIERS; DRUG COMPOUNDING; HUMANS; INJECTIONS, INTRALESIONAL; INJECTIONS, INTRAPERITONEAL; LIVER NEOPLASMS, EXPERIMENTAL; MICE; MICE, INBRED ICR; NANOPARTICLES; POLYESTERS; POLYETHYLENE GLYCOLS; POSITRON-EMISSION TOMOGRAPHY; SOLUBILITY; TIME FACTORS; TOMOGRAPHY, X-RAY COMPUTED; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 55049137346     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejpb.2008.06.016     Document Type: Article

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