Cisplatin-loaded gelatin-poly(acrylic acid) nanoparticles: Synthesis, antitumor efficiency in vivo and penetration in tumors

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 79, Issue 1, 2011, Pages 142-149

  Ding, Dan ^a   Zhu, Zhenshu ^a   Liu, Qin ^b   Wang, Jing ^a   Hu, Yong ^a   Jiang, Xiqun ^a   Liu, Baorui ^b  

^a NANJING UNIVERSITY   (China)

^b MEDICAL SCHOOL OF NANJING UNIVERSITY   (China)

Author keywords

Antitumor; Cisplatin; Drug delivery; Gelatin; Polymer nanoparticles

Indexed keywords

CARBOXYLIC ACID; CISPLATIN; GELATIN; NANOPARTICLE; POLYACRYLIC ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; AQUEOUS SOLUTION; ARTICLE; ATOMIC FORCE MICROSCOPY; CANCER SURVIVAL; CANCER TISSUE; COMPLEX FORMATION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOTOXICITY; DRUG DOSAGE FORM COMPARISON; DRUG EFFECT; DRUG EFFICACY; DRUG FORMULATION; DRUG PENETRATION; DRUG STABILITY; HUMAN; HUMAN CELL; HYDRODYNAMICS; IN VIVO STUDY; MALE; MOUSE; NANOENCAPSULATION; NONHUMAN; PARTICLE SIZE; POLYMERIZATION; SURVIVAL RATE; SURVIVAL TIME; SUSTAINED DRUG RELEASE; SYNTHESIS; THERMOSTABILITY; TRANSMISSION ELECTRON MICROSCOPY; TUMOR VASCULARIZATION; ZETA POTENTIAL;

ACRYLATES; ANIMALS; ANTINEOPLASTIC AGENTS; CISPLATIN; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG CARRIERS; DRUG COMPOUNDING; DRUG DELIVERY SYSTEMS; DRUG EVALUATION, PRECLINICAL; DRUG STABILITY; FORMAZANS; GELATIN; HUMANS; MALE; MICE; MICE, INBRED ICR; NANOPARTICLES; NEOPLASMS; TETRAZOLIUM SALTS; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 80052265439     PISSN: 09396411     EISSN: 18733441     Source Type: Journal    
DOI: 10.1016/j.ejpb.2011.01.008     Document Type: Article

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