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Volumn 285, Issue 1-2, 2012, Pages 13-19

M2 muscarinic ACh receptors sensitive BK channels mediate cholinergic inhibition of type II vestibular hair cells

Author keywords

[No Author keywords available]

Indexed keywords

ADENYLATE CYCLASE; CALCIUM CHANNEL; CYCLIC AMP; INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN; LARGE CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL; MUSCARINIC M1 RECEPTOR ANTAGONIST; MUSCARINIC M2 RECEPTOR; MUSCARINIC M2 RECEPTOR ANTAGONIST; MUSCARINIC M3 RECEPTOR ANTAGONIST; MUSCARINIC M4 RECEPTOR ANTAGONIST; MUSCARINIC RECEPTOR BLOCKING AGENT; UNCLASSIFIED DRUG;

EID: 84862823267     PISSN: 03785955     EISSN: 18785891     Source Type: Journal    
DOI: 10.1016/j.heares.2012.02.003     Document Type: Article
Times cited : (13)

References (45)
  • 1
    • 0031578578 scopus 로고    scopus 로고
    • Differential expression of alpha2-7, alpha9 and beta2-4 nicotinic acetylcholine receptor subunit mRNA in the vestibular end-organs and scarpa's ganglia of the rat
    • Anderson A.D., Troyanovskaya M., Wackym P.A. Differential expression of alpha2-7, alpha9 and beta2-4 nicotinic acetylcholine receptor subunit mRNA in the vestibular end-organs and scarpa's ganglia of the rat. Brain Res. 1997, 778:409-413.
    • (1997) Brain Res. , vol.778 , pp. 409-413
    • Anderson, A.D.1    Troyanovskaya, M.2    Wackym, P.A.3
  • 2
    • 0018652820 scopus 로고
    • Studies on the mechanism of action of acetylcholine antagonists on rat parasympathetic ganglion cells
    • Ascher P., Large W.A., Rang H.P. Studies on the mechanism of action of acetylcholine antagonists on rat parasympathetic ganglion cells. J. Physiol. 1979, 295:139-170.
    • (1979) J. Physiol. , vol.295 , pp. 139-170
    • Ascher, P.1    Large, W.A.2    Rang, H.P.3
  • 3
    • 0033754514 scopus 로고    scopus 로고
    • 2+ current is not altered in cardiac ventricular myocytes from mice lacking endothelial nitric oxide synthase
    • 2+ current is not altered in cardiac ventricular myocytes from mice lacking endothelial nitric oxide synthase. J. Physiol. 2000, 528:279-289.
    • (2000) J. Physiol. , vol.528 , pp. 279-289
    • Belevych, A.E.1    Harvey, R.D.2
  • 4
    • 0035498509 scopus 로고    scopus 로고
    • 2+ current in guinea-pig ventricular myocytes, mediated by Gβγ-dependent activation of adenylyl cyclase
    • 2+ current in guinea-pig ventricular myocytes, mediated by Gβγ-dependent activation of adenylyl cyclase. J. Physiol. 2001, 536:677-692.
    • (2001) J. Physiol. , vol.536 , pp. 677-692
    • Belevych, A.E.1    Sims, C.2    Harvey, R.D.3
  • 5
    • 0034016845 scopus 로고    scopus 로고
    • Responses to efferent activation and excitatory response-intensity relations of turtle posterior-crista afferents
    • Brichta A.M., Goldberg J.M. Responses to efferent activation and excitatory response-intensity relations of turtle posterior-crista afferents. J. Neurophysiol. 2000, 83:1224-1242.
    • (2000) J. Neurophysiol. , vol.83 , pp. 1224-1242
    • Brichta, A.M.1    Goldberg, J.M.2
  • 6
    • 0029069790 scopus 로고
    • A region of adenylyl cyclase 2 critical for regulation by G protein βγ subunits
    • Chen J., DeVivo M., Dingus J. A region of adenylyl cyclase 2 critical for regulation by G protein βγ subunits. Science 1995, 268:1166-1169.
    • (1995) Science , vol.268 , pp. 1166-1169
    • Chen, J.1    DeVivo, M.2    Dingus, J.3
  • 7
    • 0346880165 scopus 로고    scopus 로고
    • Expression of G-protein alpha subunits in the rat vestibular periphery and their chromosomal mapping
    • Cioffi J.A., Erbe C.B., Raphael R. Expression of G-protein alpha subunits in the rat vestibular periphery and their chromosomal mapping. Acta Otolaryngol. 2003, 123:1027-1034.
    • (2003) Acta Otolaryngol. , vol.123 , pp. 1027-1034
    • Cioffi, J.A.1    Erbe, C.B.2    Raphael, R.3
  • 8
    • 20444375101 scopus 로고    scopus 로고
    • Molecular characterization of two novel splice variants of G alphai2 in the rat vestibular periphery
    • Cioffi J.A., Wackym P.A., Erbe C.B. Molecular characterization of two novel splice variants of G alphai2 in the rat vestibular periphery. Brain Res. Mol. Brain Res. 2005, 137:89-97.
    • (2005) Brain Res. Mol. Brain Res. , vol.137 , pp. 89-97
    • Cioffi, J.A.1    Wackym, P.A.2    Erbe, C.B.3
  • 9
    • 0027495684 scopus 로고
    • New roles for G-protein βγ-dimers in transmembrane signalling
    • Clapham D.E., Neer E.J. New roles for G-protein βγ-dimers in transmembrane signalling. Nature 1993, 365:403-406.
    • (1993) Nature , vol.365 , pp. 403-406
    • Clapham, D.E.1    Neer, E.J.2
  • 10
    • 27144507889 scopus 로고    scopus 로고
    • Muscarinic ACh receptor activation causes transmitter release from isolated frog vestibular hair cells
    • Derbenev A.V., Linn C.L., Guth P.S. Muscarinic ACh receptor activation causes transmitter release from isolated frog vestibular hair cells. J. Neurophysiol. 2005, 94:3134-3142.
    • (2005) J. Neurophysiol. , vol.94 , pp. 3134-3142
    • Derbenev, A.V.1    Linn, C.L.2    Guth, P.S.3
  • 11
    • 0028171296 scopus 로고
    • Alpha9: an acetylcholine receptor with novel pharmacological properties expressed in rat cochlear hair cells
    • Elgoyhen A.B., Johnson D.S., Boulter J. Alpha9: an acetylcholine receptor with novel pharmacological properties expressed in rat cochlear hair cells. Cell 1994, 79:705-715.
    • (1994) Cell , vol.79 , pp. 705-715
    • Elgoyhen, A.B.1    Johnson, D.S.2    Boulter, J.3
  • 12
    • 0035852933 scopus 로고    scopus 로고
    • Alpha10: a determinant of nicotinic cholinergic receptor function in mammalian vestibular and cochlear mechanosensory hair cells
    • Elgoyhen A.B., Vetter D.E., Katz E. Alpha10: a determinant of nicotinic cholinergic receptor function in mammalian vestibular and cochlear mechanosensory hair cells. Proc. Natl. Acad. Sci. 2001, 98:3501-3506.
    • (2001) Proc. Natl. Acad. Sci. , vol.98 , pp. 3501-3506
    • Elgoyhen, A.B.1    Vetter, D.E.2    Katz, E.3
  • 13
    • 0026562725 scopus 로고
    • Hormonal stimulation of adenylyl cyclase through Gi-protein beta gamma subunits
    • Federman A.D., Conklin B.R., Schrader K.A. Hormonal stimulation of adenylyl cyclase through Gi-protein beta gamma subunits. Nature 1992, 356:159-161.
    • (1992) Nature , vol.356 , pp. 159-161
    • Federman, A.D.1    Conklin, B.R.2    Schrader, K.A.3
  • 14
    • 0029013930 scopus 로고
    • Muscarinic acetylcholine receptors: signal transduction through multiple effectors
    • Felder C.C. Muscarinic acetylcholine receptors: signal transduction through multiple effectors. FASEB J. 1995, 9:619-625.
    • (1995) FASEB J. , vol.9 , pp. 619-625
    • Felder, C.C.1
  • 15
    • 0034733668 scopus 로고    scopus 로고
    • Cholinergic synaptic inhibition of inner hair cells in the neonatal mammalian cochlea
    • Glowatzki E., Fuchs P.A. Cholinergic synaptic inhibition of inner hair cells in the neonatal mammalian cochlea. Science 2000, 288:2366-2368.
    • (2000) Science , vol.288 , pp. 2366-2368
    • Glowatzki, E.1    Fuchs, P.A.2
  • 16
    • 0022993906 scopus 로고
    • Cholinomimetics mimic efferent effects on semicircular canal afferent activity in the frog
    • Guth P.S., Norris C.H., Guth S.L. Cholinomimetics mimic efferent effects on semicircular canal afferent activity in the frog. Acta Otolaryngol. 1986, 102:194-203.
    • (1986) Acta Otolaryngol. , vol.102 , pp. 194-203
    • Guth, P.S.1    Norris, C.H.2    Guth, S.L.3
  • 17
    • 0032007872 scopus 로고    scopus 로고
    • The vestibular hair cells: post-transductional signal processing
    • Guth P.S., Perin P., Norris C.H., Valli P. The vestibular hair cells: post-transductional signal processing. Prog Neurobiol 1998, 54:193-247.
    • (1998) Prog Neurobiol , vol.54 , pp. 193-247
    • Guth, P.S.1    Perin, P.2    Norris, C.H.3    Valli, P.4
  • 18
    • 0035130757 scopus 로고    scopus 로고
    • The effect of proteolytic enzymes on the a9-nicotinic receptor-mediated response in isolated frog vestibular hair cells
    • Holt J.C., Lioudyno M., Athas G., Garcia M.M., Perin P., Guth P.S. The effect of proteolytic enzymes on the a9-nicotinic receptor-mediated response in isolated frog vestibular hair cells. Hear. Res. 2001, 152:25-42.
    • (2001) Hear. Res. , vol.152 , pp. 25-42
    • Holt, J.C.1    Lioudyno, M.2    Athas, G.3    Garcia, M.M.4    Perin, P.5    Guth, P.S.6
  • 19
    • 0141676687 scopus 로고    scopus 로고
    • A pharmacologically distinct nicotinic ACh receptor is found in a subset of frog semicircular canal hair cells
    • Holt J., Lioudyno M., Guth P.S. A pharmacologically distinct nicotinic ACh receptor is found in a subset of frog semicircular canal hair cells. J. Neurophysiol. 2003, 90:1526-1536.
    • (2003) J. Neurophysiol. , vol.90 , pp. 1526-1536
    • Holt, J.1    Lioudyno, M.2    Guth, P.S.3
  • 20
    • 0030869320 scopus 로고    scopus 로고
    • Molecular characterization of muscarinic receptors in the human vestibular periphery: implications for pharmacotherapy
    • Ishiyama A., Lopel I., Wackym P.A. Molecular characterization of muscarinic receptors in the human vestibular periphery: implications for pharmacotherapy. Am. J. Otol. 1997, 18:648-654.
    • (1997) Am. J. Otol. , vol.18 , pp. 648-654
    • Ishiyama, A.1    Lopel, I.2    Wackym, P.A.3
  • 21
    • 0032962324 scopus 로고    scopus 로고
    • Regulation of ionic currents by protein kinase A and intracellular calcium in outer hair cells isolated from the guinea-pig cochlea
    • Jagger D.J., Ashmore J.F. Regulation of ionic currents by protein kinase A and intracellular calcium in outer hair cells isolated from the guinea-pig cochlea. Pflügers Archiv 1999, 437:409-416.
    • (1999) Pflügers Archiv , vol.437 , pp. 409-416
    • Jagger, D.J.1    Ashmore, J.F.2
  • 22
    • 0025954315 scopus 로고
    • Functional responses of cloned muscarinic receptors expressed in CHO-K1 cells
    • Jones S.V., Heilman C.J., Brann M.R. Functional responses of cloned muscarinic receptors expressed in CHO-K1 cells. Mol. Pharmacol. 1991, 40:242-247.
    • (1991) Mol. Pharmacol. , vol.40 , pp. 242-247
    • Jones, S.V.1    Heilman, C.J.2    Brann, M.R.3
  • 23
    • 27644442728 scopus 로고    scopus 로고
    • The properties of ACh-induced BK currents in guinea pig type II vestibular hair cells
    • Kong W.J., Guo C.K., Zhang S., Hao J., Wang Y.J., Li Z.W. The properties of ACh-induced BK currents in guinea pig type II vestibular hair cells. Hear. Res. 2005, 209:1-9.
    • (2005) Hear. Res. , vol.209 , pp. 1-9
    • Kong, W.J.1    Guo, C.K.2    Zhang, S.3    Hao, J.4    Wang, Y.J.5    Li, Z.W.6
  • 24
    • 33746210069 scopus 로고    scopus 로고
    • Fast cholinergic efferent inhibition in guinea pig outer hair cells
    • Kong W.J., Guo C.K., Zhang S., Zhang X.W., Wang Y.J., Li Z.W. Fast cholinergic efferent inhibition in guinea pig outer hair cells. Brain Res. 2006, 1102:103-108.
    • (2006) Brain Res. , vol.1102 , pp. 103-108
    • Kong, W.J.1    Guo, C.K.2    Zhang, S.3    Zhang, X.W.4    Wang, Y.J.5    Li, Z.W.6
  • 25
    • 33845989421 scopus 로고    scopus 로고
    • The coupling of acetylcholine-induced BK channel and calcium channel in guinea pig saccular type II vestibular hair cells
    • Kong W.J., Guo C.K., Zhang X.W., Chen X., Zhang S., Li G.Q., Li Z.W., Cauwenberge P.V. The coupling of acetylcholine-induced BK channel and calcium channel in guinea pig saccular type II vestibular hair cells. Brain Res. 2007, 1129:110-115.
    • (2007) Brain Res. , vol.1129 , pp. 110-115
    • Kong, W.J.1    Guo, C.K.2    Zhang, X.W.3    Chen, X.4    Zhang, S.5    Li, G.Q.6    Li, Z.W.7    Cauwenberge, P.V.8
  • 26
    • 0036262476 scopus 로고    scopus 로고
    • Quantitation of mRNAs for M1 to M5 subtypes of muscarinic receptors in rat heart and brain cortex
    • Krejčí A., Tuček S. Quantitation of mRNAs for M1 to M5 subtypes of muscarinic receptors in rat heart and brain cortex. Mol. Pharmacol. 2002, 61:1267-1272.
    • (2002) Mol. Pharmacol. , vol.61 , pp. 1267-1272
    • Krejčí, A.1    Tuček, S.2
  • 27
    • 2342500003 scopus 로고    scopus 로고
    • Regulation of signal transduction at M2 muscarinic receptor
    • Krejčí A., Michal P., Jakubik J. Regulation of signal transduction at M2 muscarinic receptor. Physiol. Res. 2004, 53:S131-S140.
    • (2004) Physiol. Res. , vol.53
    • Krejčí, A.1    Michal, P.2    Jakubik, J.3
  • 28
    • 34247499123 scopus 로고    scopus 로고
    • Muscarinic acetylcholine receptor subtype expression in avian vestibular hair cells, nerve terminals and ganglion cells
    • Li G.Q., Kevetter G.A., Leonard R.B., Prusak D.J., Wood T.G., Correia M.J. Muscarinic acetylcholine receptor subtype expression in avian vestibular hair cells, nerve terminals and ganglion cells. Neuroscience 2007, 146:384-402.
    • (2007) Neuroscience , vol.146 , pp. 384-402
    • Li, G.Q.1    Kevetter, G.A.2    Leonard, R.B.3    Prusak, D.J.4    Wood, T.G.5    Correia, M.J.6
  • 29
    • 24044496218 scopus 로고    scopus 로고
    • A novel alpha-conotoxin, PeIA, cloned from Conus pergrandis, discriminates between rat alpha9alpha10 and alpha7 nicotinic cholinergic receptors
    • McIntosh J.M., Plazas P.V., Watkins M. A novel alpha-conotoxin, PeIA, cloned from Conus pergrandis, discriminates between rat alpha9alpha10 and alpha7 nicotinic cholinergic receptors. J. Biol. Chem. 2005, 280:30107-30112.
    • (2005) J. Biol. Chem. , vol.280 , pp. 30107-30112
    • McIntosh, J.M.1    Plazas, P.V.2    Watkins, M.3
  • 30
    • 0012280361 scopus 로고
    • Inhibition of acetylcholine release by activation of acetylcholine receptors
    • Molenaar P., Polak R.L. Inhibition of acetylcholine release by activation of acetylcholine receptors. Prog. Pharmacol. 1980, 3:39-44.
    • (1980) Prog. Pharmacol. , vol.3 , pp. 39-44
    • Molenaar, P.1    Polak, R.L.2
  • 31
    • 0033623941 scopus 로고    scopus 로고
    • + channels controls fast inhibitory synaptic transmission at auditory outer hair cells
    • + channels controls fast inhibitory synaptic transmission at auditory outer hair cells. Neuron 2000, 26:595-601.
    • (2000) Neuron , vol.26 , pp. 595-601
    • Oliver, D.1    Klöcker, N.2    Schuck, J.3
  • 32
    • 0020571159 scopus 로고
    • Peripheral organization of the vestibular efferent system in the frog: an electrophysiological study
    • Prigioni I., Valli P., Casella C. Peripheral organization of the vestibular efferent system in the frog: an electrophysiological study. Brain Res. 1983, 269:83-90.
    • (1983) Brain Res. , vol.269 , pp. 83-90
    • Prigioni, I.1    Valli, P.2    Casella, C.3
  • 33
    • 0026002674 scopus 로고
    • Light- and electron microscopy of isolated vestibular hair cells from the guinea pig
    • Scarfone E., Ulfendahl M., Löfstrand P., Flock A. Light- and electron microscopy of isolated vestibular hair cells from the guinea pig. Cell Tissue Res. 1991, 266(1):51-58.
    • (1991) Cell Tissue Res. , vol.266 , Issue.1 , pp. 51-58
    • Scarfone, E.1    Ulfendahl, M.2    Löfstrand, P.3    Flock, A.4
  • 34
    • 70349838245 scopus 로고    scopus 로고
    • Distribution of high-conductance calcium-activated potassium channels in rat vestibular epithelia
    • Schweizer F.E., Savin D., Luu C., Sultemeier D.R., Hoffman L.F. Distribution of high-conductance calcium-activated potassium channels in rat vestibular epithelia. J. Comp. Neurol. 2009, 517(2):134-145.
    • (2009) J. Comp. Neurol. , vol.517 , Issue.2 , pp. 134-145
    • Schweizer, F.E.1    Savin, D.2    Luu, C.3    Sultemeier, D.R.4    Hoffman, L.F.5
  • 35
    • 0026010576 scopus 로고
    • Muscarinic receptor hyperpolarizes cochlear hair cells of chick by activating Ca(2+)-activated K+ channels
    • Shigemoto T., Ohmori H. Muscarinic receptor hyperpolarizes cochlear hair cells of chick by activating Ca(2+)-activated K+ channels. J. Physiol. 1991, 442:669-690.
    • (1991) J. Physiol. , vol.442 , pp. 669-690
    • Shigemoto, T.1    Ohmori, H.2
  • 36
    • 0023740736 scopus 로고
    • Acetylcholine modulated potassium channel in the hair cell of the toadfish saccule
    • Steinacker A., Rojas L. Acetylcholine modulated potassium channel in the hair cell of the toadfish saccule. Hear. Res. 1988, 35:265-269.
    • (1988) Hear. Res. , vol.35 , pp. 265-269
    • Steinacker, A.1    Rojas, L.2
  • 38
    • 0026418426 scopus 로고
    • Type-specific regulation of adenylyl cyclase by G protein βγ-subunits
    • Tang W.J., Gilman A.G. Type-specific regulation of adenylyl cyclase by G protein βγ-subunits. Science 1991, 254:1500-1503.
    • (1991) Science , vol.254 , pp. 1500-1503
    • Tang, W.J.1    Gilman, A.G.2
  • 39
    • 0033814975 scopus 로고    scopus 로고
    • Mixed nicotinic-muscarinic properties of alpha9 nicotinic cholinergical receptor
    • Verbitsky M., Rothlin C.V., Katz E. Mixed nicotinic-muscarinic properties of alpha9 nicotinic cholinergical receptor. Neuropharmacology 2000, 39:2515-2524.
    • (2000) Neuropharmacology , vol.39 , pp. 2515-2524
    • Verbitsky, M.1    Rothlin, C.V.2    Katz, E.3
  • 40
    • 0029970158 scopus 로고    scopus 로고
    • Muscarinic acetylcholine receptor subtype mRNAs in the human and rat vestibular periphery
    • Wackym P.A., Chen C.T., Ishiyama A. Muscarinic acetylcholine receptor subtype mRNAs in the human and rat vestibular periphery. Cell Biol. Int. 1996, 20:187-192.
    • (1996) Cell Biol. Int. , vol.20 , pp. 187-192
    • Wackym, P.A.1    Chen, C.T.2    Ishiyama, A.3
  • 41
    • 0034708541 scopus 로고    scopus 로고
    • Adenylyl cyclase isoforms in the vestibular periphery of the rat
    • Wackym P.A., Troyanovskaya M., Popper P. Adenylyl cyclase isoforms in the vestibular periphery of the rat. Brain Res. 2000, 859:378-380.
    • (2000) Brain Res. , vol.859 , pp. 378-380
    • Wackym, P.A.1    Troyanovskaya, M.2    Popper, P.3
  • 42
    • 17244366311 scopus 로고    scopus 로고
    • G-protein Golfalpha (GNAL) is expressed in the vestibular end organs and primary afferent neurons of Rattus norvegicus
    • Wackym P.A., Cioffi J.A., Erbe C.B. G-protein Golfalpha (GNAL) is expressed in the vestibular end organs and primary afferent neurons of Rattus norvegicus. J. Vestib. Res. 2005, 15:11-15.
    • (2005) J. Vestib. Res. , vol.15 , pp. 11-15
    • Wackym, P.A.1    Cioffi, J.A.2    Erbe, C.B.3
  • 43
    • 78149478664 scopus 로고    scopus 로고
    • BK channels mediate cholinergic inhibition of high frequency cochlear hair cells
    • Wersinger E., McLean W.J., Fuchs P.A. BK channels mediate cholinergic inhibition of high frequency cochlear hair cells. PLoS One 2010, 5:e13836.
    • (2010) PLoS One , vol.5
    • Wersinger, E.1    McLean, W.J.2    Fuchs, P.A.3
  • 44
    • 0028255908 scopus 로고
    • The role of inositol trisphosphate on ACh-induced outward currents in bullfrog saccular hair cells
    • Yoshida N., Shigemoto T., Sugai T. The role of inositol trisphosphate on ACh-induced outward currents in bullfrog saccular hair cells. Brain Res. 1994, 644:90-100.
    • (1994) Brain Res. , vol.644 , pp. 90-100
    • Yoshida, N.1    Shigemoto, T.2    Sugai, T.3


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