Effects of taraxasterol on inflammatory responses in lipopolysaccharide- induced RAW 264.7 macrophages

Journal of Ethnopharmacology

Volumn 141, Issue 1, 2012, Pages 206-211

  Zhang, Xuemei ^a   Xiong, Huanzhang ^a   Liu, Liben ^a  

^a YANBIAN UNIVERSITY   (China)

Author keywords

Cytokines; Nitric oxide (NO); Nuclear factor B (NF B); Prostaglandin E 2 (PGE 2); Taraxasterol

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; NITRIC OXIDE; PROSTAGLANDIN E2; TARAXASTEROL; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL VIABILITY; CELLULAR DISTRIBUTION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOPLASM; IMMUNOCYTOCHEMISTRY; IN VITRO STUDY; INFLAMMATION; MACROPHAGE ACTIVATION; MOUSE; NONHUMAN; PROTEIN LOCALIZATION;

ANIMALS; ANTI-INFLAMMATORY AGENTS; CELL LINE; CELL SURVIVAL; DINOPROSTONE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUGS, CHINESE HERBAL; ENZYME-LINKED IMMUNOSORBENT ASSAY; IMMUNOHISTOCHEMISTRY; INFLAMMATION MEDIATORS; INTERLEUKIN-1BETA; INTERLEUKIN-6; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; NF-KAPPA B; NITRIC OXIDE; PHYTOTHERAPY; PLANTS, MEDICINAL; SIGNAL TRANSDUCTION; STEROLS; TRITERPENES; TUMOR NECROSIS FACTOR-ALPHA;

MURINAE; TARAXACUM OFFICINALE;

EID: 84862820723     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2012.02.020     Document Type: Article

References (39)

1. B.B. Aggarwal, and K. Natarajan Tumor necrosis factors: developments during the last decade European Cytokine Network 7 1996 93 124
2. V.U. Ahmad, S. Yasmeen, Z. Ali, M.A. Khan, M.I. Choudhary, F. Akhtar, G.A. Miana, and M. Zahid Taraxacin, a new guaianolide from Taraxacum wallichii Journal of Natural Products 63 2000 1010 1011
3. P.A. Baeuerle, and D. Baltimore NF-kappa B: ten years after Cell 87 1996 13 20
4. Y. Bayon, M.A. Ortiz, F.J. Lopez-Hernandez, F. Gao, M. Karin, M. Pfahl, and F.J. Piedrafita Inhibition of IkappaB kinase by a new class of retinoid-related anticancer agents that induce apoptosis Molecular and Cellular Biology 23 2003 1061 1074
5. B. Beutler, and A. Cerami The biology of cachectin/TNF-α primary mediator of the host response Annual Review of Immunology 7 1989 625 655
6. X.Y. Cao, M. Dong, J.Z. Shen, B.B. Wu, C.M. Wu, X.D. Du, Z. Wang, Y.T. Qi, and B.Y. Li Tilmicosin and tylosin have anti-inflammatory properties via modulation of COX-2 and iNOS gene expression and production of cytokines in LPS-induced macrophages and monocytes International Journal of Antimicrobial Agents 27 2006 431 438
7. J. Cohen The immunopathogenesis of sepsis Nature 420 2002 885 891
8. M.P. Glauser The inflammatory cytokines. New developments in the pathophysiology and treatment of septic shock Drugs 52 1996 9 17
9. M. Guha, and N. Mackman LPS induction of gene expression in human monocytes Cellular Signalling 13 2001 85 94
10. A. Ialenti, S. Moncada, and M. Di Rosa Modulation of adjuvant arthritis by endogenous nitric oxide British Journal of Pharmacology 110 1993 701 706
11. H.J. Jeon, H.J. Kang, H.J. Jung, Y.S. Kang, C.J. Lim, Y.M. Kim, and E.H. Park Anti-inflammatory activity of Taraxacum officinale Journal of Ethnopharmacology 115 2008 82 88
12. J.B. Kim, A.R. Han, E.Y. Park, J.Y. Kim, W. Cho, J. Lee, E.K. Seo, and K.T. Lee Inhibition of LPS-induced iNOS, COX-2 and cytokines expression by poncirin through the NF-κB inactivation in RAW 264.7 macrophage cells Biological & Pharmaceutical Bulletin 30 2007 2345 2351
13. N.D. Kim, E.M. Kim, K.W. Kang, M.K. Cho, S.Y. Choi, and S.G. Kim Ginsenoside Rg3 inhibits phenylephrine-induced vascular contraction through induction of nitric oxide synthase British Journal of Pharmacology 140 2003 661 670
14. Y.H. Kim, S.H. Lee, J.Y. Lee, S.W. Choi, J.W. Park, and T.K. Kwon Triptolide inhibits murine-inducible nitric oxide synthase expression by down-regulating lipopolysaccharide induced activity of nuclear factor-kappa B and c-Jun NH2-terminal kinase European Journal of Pharmacology 494 2004 1 9
15. W. Kisiel, and B. Barszcz Further sesquiterpenoids and phenolics from Taraxacum officinale Fitoterapia 71 2000 269 273
16. Y.J. Koh, D.S. Cha, J.S. Ko, H.J. Park, and H.D. Choi Anti-inflammatory effect of Taraxacum officinale leaves on lipopolysaccharide-induced inflammatory responses in RAW 264.7 cells Journal of Medicinal Food 13 2010 870 878
17. M. Lappas, M. Permezel, H.M. Georgiou, and G.E. Rice Nuclear factor kappa B regulation of proinflammatory cytokines in human gestational tissues in vitro Biology of Reproduction 67 2002 668 673
18. Y.L. Leu, Y.L. Wang, S.C. Huang, and L.S. Shi Chemical constituents from roots of Taraxacum formosanum Chemical and Pharmaceutical Bulletin 53 2005 853 855
19. Q. Li, and I.M. Verma NF-kappaB regulation in the immune system Nature Reviews Immunology 2 2002 725 734
20. L.B. Liu, H.Z. Xiong, J.Q. Ping, Y.L. Ju, and X.M. Zhang Taraxacum officinale protects against lipopolysaccharide-induced acute lung injury in mice Journal of Ethnopharmacology 130 2010 389 394
21. D.N. Mannel, and B. Echtenacher TNF in the inflammatory response Chemical Immunology 74 2000 141 161
22. S.I. Miller, R.K. Ernst, and M.W. Bader LPS, TLR4 and infectious disease diversity Nature Reviews Microbiology 3 2005 36 46
23. R.G. Molloy, J.A. Mannick, and M.L. Rodrick Cytokines, sepsis and immunomodulation The British Journal of Surgery 80 1993 289 297
24. L.C. Mongan, T. Jones, and G. Patrick Cytokine and free radical responses of alveolar macrophages in vitro to asbestos fibres Cytokine 12 2000 1243 1247
25. S. Olsson, and R. Sundler The role of lipid rafts in LPS-induced signaling in a macrophage cell line Molecular Immunology 43 2006 607 612
26. C.M. Park, J.Y. Park, K.H. Noh, J.H. Shin, and Y.S. Song Taraxacum officinale Weber extracts inhibit LPS-induced oxidative stress and intric oxide production via the NF-κB modulation in RAW 264.7 cells Journal of Ethnopharmacology 133 2011 834 842
27. I. Posadas, M.C. Terencio, I. Guillén, M.L. Ferrándiz, J. Coloma, M. Payá, and M.J. Alcaraz Co-regulation between cyclo-oxygenase-2 and inducible nitric oxide synthase expression in the time-course of murine inflammation Naunyn-Schmiedeberg's Archives of Pharmacology 361 2000 98 106
28. C.R. Raetz Bacterial endotoxins: extraordinary lipids that activate eucaryotic signal transduction Journal of Bacteriology 175 1993 5745 5753
29. J.L. Ríos, M.C. Recio, S. Máñez, and R.M. Giner Natural triterpenoids as anti-inflammatory agents Studies in Natural Products Chemistry 22 2000 93 143
30. K. Schütz, R. Carle, and A. Schieber Taraxacum-a review on its phytochemical and pharmacological profile Journal of Ethnopharmacology 107 2006 313 323
31. S.W. Seo, H.N. Koo, H.J. An, K.B. Kwon, B.C. Lim, E.A. Seo, D.G. Ryu, G. Moon, H.Y. Kim, H.M. Kim, and S.H. Hong Taraxacum officinale protects against cholecystokinin-induced acute pancreatitis in rats World Journal of Gastroenterology 11 2005 597 599
32. Y.Z. Shi, Z.Z. Tu, D.L. Tang, H.L. Zhang, M.D. Liu, K.K. Wang, S.K. Calderwood, and X. Xiao The inhibition of LPS-induced production of inflammatory cytokines by HSP70 involves inactivation of the NF-κB pathway but not the MAPK pathways Shock 26 2006 277 284
33. R. Shimazu, S. Akashi, H. Ogata, Y. Nagai, K. Fukudome, K. Miyake, and M. Kimoto MD-2, a molecule that confers lipopolysaccharide responsiveness on Toll-like receptor 4 The Journal of Experimental Medicine 189 1999 1777 1782
34. B. Sweeney, M. Vora, C. Ulbricht, and E. Basch Evidence-based systematic review of dandelion (Taraxacum officinale) by natural standard research collaboration Journal of Herbal Pharmacotherapy 5 2005 79 93
35. K. Takeda, and S. Akira Regulation of innate immune responses by Toll-like receptors Japanese Journal of Infectious Diseases 54 2001 209 219
36. J. Van Snick IL-6: an overview Annual Review of Immunology 8 1990 253 278
37. J.R. Vane, Y.S. Bakhle, and R.M. Botting Cyclooxygenases 1 and 2 Annual Review of Pharmacology and Toxicology 38 1998 97 120
38. M.A. West, S.C. Seatter, J. Bellingham, and L. Clarir Mechanisms of reprogrammed macrophage endotoxin signal transduction after lipopolysaccharide pretreatment Surgery 118 1995 220 228
39. Y. Yamamoto, and R.B. Gaynor Therapeutic potential of inhibition of the NF-κB pathway in the treatment of inflammation and cancer The Journal of Clinical Investigation 107 2001 135 142