Inhibition of LPS binding to MD-2 co-receptor for suppressing TLR4-mediated expression of inflammatory cytokine by 1-dehydro-10-gingerdione from dietary ginger

Biochemical and Biophysical Research Communications

Volumn 419, Issue 4, 2012, Pages 735-740

  Park, Sun Hong ^a   Kyeong, Min Sik ^a   Hwang, Yuri ^a   Ryu, Shi Yong ^b   Han, Sang Bae ^a   Kim, Youngsoo ^a  

^a Chungbuk National University   (South Korea)

^b Korea Research Institute of Chemical Technology   (South Korea)

Author keywords

1 Dehydro 10 gingerdione; Anti inflammatory mechanism; Ginger (Zingiber officinale); Myeloid differentiation protein 2; Toll like receptor 4

Indexed keywords

1 DEHYDRO 10 GINGERDIONE; BETA INTERFERON; GAMMA INTERFERON INDUCIBLE PROTEIN 10; GINGER EXTRACT; GINGEROL; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERFERON REGULATORY FACTOR 3; INTERLEUKIN 1BETA; LIPOPOLYSACCHARIDE; MYELOID DIFFERENTIATION FACTOR 88; MYELOID DIFFERENTIATION PROTEIN 2; PROTEIN; SHOGAOL; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME INHIBITION; GENE EXPRESSION; GINGER; MACROPHAGE; PRIORITY JOURNAL;

ADAPTOR PROTEINS, VESICULAR TRANSPORT; ANIMALS; CYTOKINES; DIET; GENE EXPRESSION; GINGER; GUAIACOL; INFLAMMATION; INTERFERON REGULATORY FACTOR-3; LIPOPOLYSACCHARIDES; LYMPHOCYTE ANTIGEN 96; MACROPHAGES; MICE; MYELOID DIFFERENTIATION FACTOR 88; NF-KAPPA B; TOLL-LIKE RECEPTOR 4; TRANSCRIPTION FACTOR AP-1;

ZINGIBER OFFICINALE;

EID: 84862818468     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2012.02.091     Document Type: Article

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