Antiproliferative effects of local anesthetics on mesenchymal stem cells: Potential implications for tumor spreading and wound healing

Anesthesiology

Volumn 116, Issue 4, 2012, Pages 841-856

  Lucchinetti, Eliana ^a   Awad, Ahmed E ^a   Rahman, Mamoona ^a   Feng, Jianhua ^b   Lou, Phing How ^a   Zhang, Liyan ^a   Ionescu, Lavinia ^a   Lemieux, Hélène ^a   Thébaud, Bernard ^a   Zaugg, Michael ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

^b UNIVERSITY OF ZURICH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

BUPIVACAINE; LACTATE DEHYDROGENASE; LIDOCAINE; LIPOCORTIN 5; PHOSPHATIDYLSERINE; PROPIDIUM IODIDE; ROPIVACAINE; STEROL;

ANIMAL CELL; ANTIPROLIFERATIVE ACTIVITY; ARTICLE; BONE MARROW CELL; CANCER PATIENT; CARCINOGENESIS; CELL CYCLE; CELL FUNCTION; CELL PROLIFERATION; COLONY FORMATION; CONTROLLED STUDY; IN VITRO STUDY; LIPID METABOLISM; LYSOSOME; MESENCHYMAL STEM CELL; MICROARRAY ANALYSIS; MITOCHONDRION; MOUSE; NONHUMAN; OSTEOBLAST; PHOSPHOLIPID METABOLISM; PRIORITY JOURNAL; WOUND HEALING;

ANESTHETICS, LOCAL; ANIMALS; CELL PROLIFERATION; CELL TRANSFORMATION, NEOPLASTIC; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; MESENCHYMAL STEM CELLS; MICE; MICE, INBRED C57BL; WOUND HEALING;

EID: 84862807188     PISSN: 00033022     EISSN: 15281175     Source Type: Journal    
DOI: 10.1097/ALN.0b013e31824babfe     Document Type: Article

References (53)

1. Kidd S, Spaeth E, Dembinski JL, Dietrich M, Watson K, Klopp A, Battula VL, Weil M, Andreeff M, Marini FC: Direct evidence of cell tropism for tumor and wounding microenvironments using in vivo bioluminescent imaging. Stem Cells 2009; 27:2614-23
2. Dvorak HF: Tumors: Wounds that do not heal. Similarities between tumor stroma generation and wound healing. N Engl J Med 1986; 315:1650-9
3. Pittenger MF, Mackay AM, Beck SC, Jaiswal RK, Douglas R, Mosca JD, Moorman MA, Simonetti DW, Craig S, Marshak DR: Multilineage potential of adult human cells. Science 1999; 284:143-7 (Pubitemid 29282067)
4. Beckermann BM, Kallifatidis G, Groth A, Frommhold D, Apel A, Mattern J, Salnikov AV, Moldenhauer G, Wagner W, Diehlmann A, Saffrich R, Schubert M, Ho AD, Giese N, Büchler MW, Friess H, Büchler P, Herr I: VEGF expression by cells contributes to angiogenesis in pancreatic carcinoma. Br J Cancer 2008; 99:622-31
5. Karnoub AE, Dash AB, Vo AP, Sullivan A, Brooks MW, Bell GW, Richardson AL, Polyak K, Tubo R, Weinberg RA: cells within tumour stroma promote breast cancer metastasis. Nature 2007; 449:557-63 (Pubitemid 47525152)
6. Zhu W, Xu W, Jiang R, Qian H, Chen M, Hu J, Cao W, Han C, Chen Y: Mesenchymal stem cells derived from bone marrow favor tumor cell growth in vivo. Exp Mol Pathol 2006; 80:267-74
7. Kinnaird T, Stabile E, Burnett MS, Lee CW, Barr S, Fuchs S, Epstein SE: Marrow-derived stromal cells express genes encoding a broad spectrum of arteriogenic cytokines and promote in vitro and in vivo arteriogenesis through paracrine mechanisms. Circ Res 2004; 94:678-85 (Pubitemid 38387752)
8. Galbes O, Bourret A, Nouette-Gaulain K, Pillard F, Matecki S, Py G, Mercier J, Capdevila X, Philips A: N-acetylcysteine protects against bupivacaine-induced myotoxicity caused by oxidative and sarcoplasmic reticulum stress in human skeletal myotubes. ANESTHESIOLOGY 2010; 113:560-9
9. Scherb MB, Han SH, Courneya JP, Guyton GP, Schon LC: Effect of bupivacaine on cultured tenocytes. Orthopedics 2009; 32:26
10. Gottschalk A, Sharma S, Ford J, Durieux ME, Tiouririne M: Review article: The role of the perioperative period in recurrence after cancer surgery. Anesth Analg 2010; 110:1636-43
11. Dominici M, Le Blanc K, Mueller I, Slaper-Cortenbach I, Marini F, Krause D, Deans R, Keating A, Prockop DJ, Horwitz E: Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement. Cytotherapy 2006; 8:315-7 (Pubitemid 44269669)
12. Peister A, Mellad JA, Larson BL, Hall BM, Gibson LF, Prockop DJ: Adult stem cells from bone marrow (MSCs) isolated from different strains of inbred mice vary in surface epitopes, rates of proliferation, and differentiation potential. Blood 2004; 103:1662-8 (Pubitemid 38268957)
13. Pochampally R: Colony forming unit assays for MSCs. Methods Mol Biol 2008; 449:83-91
14. Fried J, Perez AG, Clarkson BD: Flow cytofluorometric analysis of cell cycle distributions using propidium iodide. Properties of the method and mathematical analysis of the data. J Cell Biol 1976; 71:172-81
15. Rodriguez LG, Wu X, Guan JL: Wound-healing assay. Methods Mol Biol 2005; 294:23-9
16. Srere PA: Citrate synthase. Methods Enzymol 1969; 13:3-11
17. Brazma A, Hingamp P, Quackenbush J, Sherlock G, Spellman P, Stoeckert C, Aach J, Ansorge W, Ball CA, Causton HC, Gaasterland T, Glenisson P, Holstege FC, Kim IF, Markowitz V, Matese JC, Parkinson H, Robinson A, Sarkans U, Schulze- Kremer S, Stewart J, Taylor R, Vilo J, Vingron M: Minimum information about a microarray experiment (MIAME)-toward standards for microarray data. Nat Genet 2001; 29:365-71 (Pubitemid 34326681)
18. Lucchinetti E, Hofer C, Bestmann L, Hersberger M, Feng J, Zhu M, Furrer L, Schaub MC, Tavakoli R, Genoni M, Zollinger A, Zaugg M: Gene regulatory control of myocardial energy metabolism predicts postoperative cardiac function in patients undergoing off-pump coronary artery bypass graft surgery: Inhalational versus intravenous anesthetics. ANESTHESIOLOGY 2007; 106:444-57
19. Subramanian A, Tamayo P, Mootha VK, Mukherjee S, Ebert BL, Gillette MA, Paulovich A, Pomeroy SL, Golub TR, Lander ES, Mesirov JP: Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles. Proc Natl Acad Sci USA 2005; 102:15545-50
20. Fu X, Han B, Cai S, Lei Y, Sun T, Sheng Z: Migration of bone marrow-derived cells induced by tumor necrosis factor-alpha and its possible role in wound healing. Wound Repair Regen 2009; 17:185-91
21. Tanaka Y, Maruo A, Fujii K, Nomi M, Nakamura T, Eto S, Minami Y: Intercellular adhesion molecule 1 discriminates functionally different populations of human osteoblasts: Characteristic involvement of cell cycle regulators. J Bone Miner Res 2000; 15:1912-23
22. Exadaktylos AK, Buggy DJ, Moriarty DC, Mascha E, Sessler DI: Can anesthetic technique for primary breast cancer surgery affect recurrence or metastasis? ANESTHESIOLOGY 2006; 105:660-4 (Pubitemid 44477309)
23. Biki B, Mascha E, Moriarty DC, Fitzpatrick JM, Sessler DI, Buggy DJ: Anesthetic technique for radical prostatectomy surgery affects cancer recurrence: A retrospective analysis. ANESTHESIOLOGY 2008; 109:180-7
24. Christopherson R, James KE, Tableman M, Marshall P, Johnson FE: Long-term survival after colon cancer surgery: A variation associated with choice of anesthesia. Anesth Analg 2008; 107:325-32
25. Schlagenhauff B, Ellwanger U, Breuninger H, Stroebel W, Rassner G, Garbe C: Prognostic impact of the type of anaesthesia used during the excision of primary cutaneous melanoma. Melanoma Res 2000; 10:165-9 (Pubitemid 30256879)
26. Martinsson T: Ropivacaine inhibits serum-induced proliferation of colon adenocarcinoma cells in vitro. J Pharmacol Exp Ther 1999; 288:660-4
27. Klopp AH, Gupta A, Spaeth E, Andreeff M, Marini F 3rd: Dissecting a discrepancy in the literature: Do cells support or suppress tumor growth? Stem Cells 2011; 29:11-9
28. Wong RS: Mesenchymal stem cells: Angels or demons? J Biomed Biotechnol 2011; 2011:459510
29. Patel SA, Dave MA, Murthy RG, Helmy KY, Rameshwar P: Metastatic breast cancer cells in the bone marrow microenvironment: Novel insights into oncoprotection. Oncol Rev 2011; 5:93-102
30. Wu Y, Chen L, Scott PG, Tredget EE: cells enhance wound healing through differentiation and angiogenesis. Stem Cells 2007; 25:2648-59 (Pubitemid 47582758)
31. van Haaften T, Byrne R, Bonnet S, Rochefort GY, Akabutu J, Bouchentouf M, Rey-Parra GJ, Galipeau J, Haromy A, Eaton F, Chen M, Hashimoto K, Abley D, Korbutt G, Archer SL, Thébaud B: Airway delivery of cells prevents arrested alveolar growth in neonatal lung injury in rats. Am J Respir Crit Care Med 2009; 180:1131-42
32. Nouette-Gaulain K, Sirvent P, Canal-Raffin M, Morau D, Malgat M, Molimard M, Mercier J, Lacampagne A, Sztark F, Capdevila X: Effects of intermittent femoral nerve injections of bupivacaine, levobupivacaine, and ropivacaine on mitochondrial energy metabolism and intracellular calcium homeostasis in rat psoas muscle. ANESTHESIOLOGY 2007; 106:1026-34
33. Nouette-Gaulain K, Bringuier S, Canal-Raffin M, Bernard N, Lopez S, Dadure C, Masson F, Mercier J, Sztark F, Rossignol R, Capdevila X: Time course of mitochondrial metabolism alterations to repeated injections of bupivacaine in rat muscle. Can J Anaesth 2010; 57:836-42
34. Nouette-Gaulain K, Forestier F, Malgat M, Marthan R, Mazat JP, Sztark F: Effects of bupivacaine on mitochondrial energy metabolism in heart of rats following exposure to chronic hypoxia. ANESTHESIOLOGY 2002; 97:1507-11 (Pubitemid 35417450)
35. Fawcett H, Mader JS, Robichaud M, Giacomantonio C, Hoskin DW: Contribution of reactive oxygen species and caspase-3 to apoptosis and attenuated ICAM-1 expression by paclitaxel-treated MDA-MB-435 breast carcinoma cells. Int J Oncol 2005; 27:1717-26
36. Byun HO, Kim HY, Lim JJ, Seo YH, Yoon G: Mitochondrial dysfunction by complex II inhibition delays overall cell cycle progression via reactive oxygen species production. J Cell Biochem 2008; 104:1747-59
37. Moldovan GL, Pfander B, Jentsch S: PCNA, the maestro of the replication fork. Cell 2007; 129:665-79 (Pubitemid 46802385)
38. Gazitt Y, Erdos GW, Cohen RJ: Ultrastructural localization and fluctuation in the level of the proliferating cell nuclear antigen and myc oncoproteins in synchronized neuroblastoma cells. Cancer Res 1993; 53:1899-905 (Pubitemid 23127122)
39. Nakakuki M, Shimano H, Inoue N, Tamura M, Matsuzaka T, Nakagawa Y, Yahagi N, Toyoshima H, Sato R, Yamada N: A transcription factor of lipid synthesis, sterol regulatory element- binding protein (SREBP)-1a causes G(1) cell-cycle arrest after accumulation of cyclin-dependent kinase (cdk) inhibitors. FEBS J 2007; 274:4440-52 (Pubitemid 47301706)
40. Teunissen BE, Smeets PJ, Willemsen PH, De Windt LJ, Van der Vusse GJ, Van Bilsen M: Activation of PPARdelta inhibits cardiac fibroblast proliferation and the transdifferentiation into myofibroblasts. Cardiovasc Res 2007; 75:519-29 (Pubitemid 47080971)
41. AnthérieuS, Rogue A, Fromenty B, Guillouzo A, Robin MA: Induction of vesicular steatosis by amiodarone and tetracycline is associated with up-regulation of lipogenic genes in HepaRG cells. Hepatology 2011; 53:1895-905
42. Goldstein JL, DeBose-Boyd RA, Brown MS: Protein sensors for membrane sterols. Cell 2006; 124:35-46
43. Murphy P, Alexander P, Senior PV, Fleming J, Kirkham N, Taylor I: Mechanisms of organ selective tumour growth by bloodborne cancer cells. Br J Cancer 1988; 57:19-31 (Pubitemid 18067098)
44. Padera R, Bellas E, Tse JY, Hao D, Kohane DS: Local myotoxicity from sustained release of bupivacaine from microparticles. ANESTHESIOLOGY 2008; 108:921-8 (Pubitemid 351589489)
45. Afsharimani B, Cabot P, Parat MO: Morphine and tumor growth and metastasis. Cancer Metastasis Rev 2011; 30:225-38
46. Takemoto Y, Li TS, Kubo M, Ohshima M, Ueda K, Harada E, Enoki T, Okamoto M, Mizukami Y, Murata T, Hamano K: Operative injury accelerates tumor growth by inducing mobilization and recruitment of bone marrow-derived stem cells. Surgery 2011; 149:792-800
47. Dawson MR, Chae SS, Jain RK, Duda DG: Direct evidence for lineage-dependent effects of bone marrow stromal cells on tumor progression. Am J Cancer Res 2011; 1:144-54
48. Miura M, Miura Y, Padilla-Nash HM, Molinolo AA, Fu B, Patel V, Seo BM, Sonoyama W, Zheng JJ, Baker CC, Chen W, Ried T, Shi S: Accumulated chromosomal instability in murine bone marrow cells leads to malignant transformation. Stem Cells 2006; 24:1095-103 (Pubitemid 44464742)
49. Inuzuka T, Tsuda M, Tanaka S, Kawaguchi H, Higashi Y, Ohba Y: Integral role of transcription factor 8 in the negative regulation of tumor angiogenesis. Cancer Res 2009; 69: 1678-84
50. Banerjee S, Byrd JN, Gianino SM, Harpstrite SE, Rodriguez FJ, Tuskan RG, Reilly KM, Piwnica-Worms DR, Gutmann DH: The neurofibromatosis type 1 tumor suppressor controls cell growth by regulating signal transducer and activator of transcription-3 activity in vitro and in vivo. Cancer Res 2010; 70:1356-66
51. Tso CL, Shintaku P, Chen J, Liu Q, Liu J, Chen Z, Yoshimoto K, Mischel PS, Cloughesy TF, Liau LM, Nelson SF: Primary glioblastomas express -like properties. Mol Cancer Res 2006; 4:607-19 (Pubitemid 44497214)
52. Doǧan N, Uçok C, Korkmaz C, Uçok O, Karasu HA: The effects of articaine hydrochloride on wound healing: An experimental study. J Oral Maxillofac Surg 2003; 61:1467-70 (Pubitemid 37464520)
53. Waite A, Gilliver SC, Masterson GR, Hardman MJ, Ashcroft GS: Clinically relevant doses of lidocaine and bupivacaine do not impair cutaneous wound healing in mice. Br J Anaesth 2010; 104:768-73