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European Journal of Medicinal Chemistry

Volumn 49, Issue , 2012, Pages 48-54

Synthesis and biological evaluation of conjugates of deoxypodophyllotoxin and 5-FU as inducer of caspase-3 and -7

(6) Huang, Wen Ting a Liu, Jie a Liu, Jian Fei a Hui, Ling c Ding, Yi Lan d Chen, Shi Wu a,b

a LANZHOU UNIVERSITY (China)

b LANZHOU UNIVERSITY (China)

c LANZHOU GENERAL HOSPITAL (China)

d Lanzhou Maternal and Child Health Care Hospital (China)

Author keywords

5 FU; Antineoplastic agents; Apoptosis; Caspase; Podophyllotoxin

Indexed keywords

4 NITROPHENYL 2 N1 5 FLUOROURACIL YLACETATE; 4' O (5 FLUOROURACIL ACETIC) DEXTRO METHINE 4 DEOXYL 4' O DEMETHYLPODOPHYLLIC ESTER; 4' O (5 FLUOROURACIL ACETIC) PHENYLALANINE 4 DEOXYL 4' O DEMETHYL ESTER; 4' O (5 FLUOROURACIL ACETIC)ALANINE 4 DEOXYL 4' O DEMETHYLPODOPHYLLIC ESTER; 4' O (5 FLUOROURACIL ACETIC)LEUCINE 4 DEOXYL 4' O DEMETHYLPODOPHYLLIC ESTER; 4' O (5 FLUOROURACIL ACETIC)METHINE 4 DEOXYL 4' O DEMETHYLPODOPHYLLIC ESTER; 4' O (5 FLUOROURACIL ACETIC)VALINE 4 DEOXYL 4' O DEMETHYLPODOPHYLLIC ESTER; 4' O 5 FLUOROURACIL ACETIC ACID 4 DEOXYL 4' O DEMETHYLPODOPHYLLIC ESTER; ANTINEOPLASTIC AGENT; CASPASE 3; CASPASE 7; DEOXYPODOPHYLLOTOXIN; ETOPOSIDE; FLUOROURACIL; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL CYCLE PROGRESSION; CONTROLLED STUDY; CYTOTOXICITY; DRUG SCREENING; DRUG SYNTHESIS; ENZYME INDUCTION; G2 PHASE CELL CYCLE CHECKPOINT; HUMAN; HUMAN CELL; M PHASE CELL CYCLE CHECKPOINT;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CASPASE 3; CASPASE 7; CELL LINE, TUMOR; ENZYME ACTIVATION; FLUOROURACIL; G2 PHASE CELL CYCLE CHECKPOINTS; HUMANS; M PHASE CELL CYCLE CHECKPOINTS; NEOPLASMS; PODOPHYLLOTOXIN;

EID: 84862803685 PISSN: 02235234 EISSN: 17683254 Source Type: Journal
DOI: 10.1016/j.ejmech.2011.12.005 Document Type: Article

Times cited : (37)

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