Dexmedetomidine prevents remifentanil-induced postoperative hyperalgesia and decreases spinal tyrosine phosphorylation of N-methyl-d-aspartate receptor 2B subunit

Brain Research Bulletin

Volumn 87, Issue 4-5, 2012, Pages 427-431

  Zheng, YaGuo ^a   Cui, SongQing ^b   Liu, Yue ^a   Zhang, Juan ^a   Zhang, Wei ^a   Zhang, Jing ^a   Gu, XiaoPing ^a   Ma, ZhengLiang ^a  

^a MEDICAL SCHOOL OF NANJING UNIVERSITY   (China)

^b NANTONG UNIVERSITY   (China)

Author keywords

Dexmedetomidine; N methyl d aspartate receptor; Opioid induced hyperalgesia; Remifentanil

Indexed keywords

DEXMEDETOMIDINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; REMIFENTANIL; TYROSINE;

ALLODYNIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIHYPERALGESIC ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; INCISION PAIN; MALE; NONHUMAN; PAIN; POSTOPERATIVE HYPERALGESIA; POSTOPERATIVE PAIN; PREMEDICATION; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; SPINAL CORD; SURGICAL TECHNIQUE; THERMAL HYPERALGESIA; WESTERN BLOTTING;

ANALGESICS, NON-NARCOTIC; ANALGESICS, OPIOID; ANIMALS; BLOTTING, WESTERN; DEXMEDETOMIDINE; DISEASE MODELS, ANIMAL; HYPERALGESIA; MALE; PAIN, POSTOPERATIVE; PHOSPHORYLATION; PIPERIDINES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, N-METHYL-D-ASPARTATE; SPINAL CORD; TYROSINE;

EID: 84862796184     PISSN: 03619230     EISSN: 18732747     Source Type: Journal    
DOI: 10.1016/j.brainresbull.2012.01.009     Document Type: Article

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