-
1
-
-
37349025432
-
Foxo3a is activated in response to hypoxic stress and inhibits HIF-1-induced apoptosis via regulation of CITED2
-
Bakker W.J., Harris I.S., Mak T.W. Foxo3a is activated in response to hypoxic stress and inhibits HIF-1-induced apoptosis via regulation of CITED2. Mol. Cell 2007, 28:941-953.
-
(2007)
Mol. Cell
, vol.28
, pp. 941-953
-
-
Bakker, W.J.1
Harris, I.S.2
Mak, T.W.3
-
2
-
-
35848954507
-
Peroxiredoxin 2 overexpression protects cortical neuronal cultures from ischemic and oxidative injury but not glutamate excitotoxicity, whereas Cu/Zn superoxide dismutase 1 overexpression protects only against oxidative injury
-
Boulos S., Meloni B.P., Arthur P.G., Bojarski C., Knucke N.W. Peroxiredoxin 2 overexpression protects cortical neuronal cultures from ischemic and oxidative injury but not glutamate excitotoxicity, whereas Cu/Zn superoxide dismutase 1 overexpression protects only against oxidative injury. J. Neurosci. Res. 2007, 85:3089-3097.
-
(2007)
J. Neurosci. Res.
, vol.85
, pp. 3089-3097
-
-
Boulos, S.1
Meloni, B.P.2
Arthur, P.G.3
Bojarski, C.4
Knucke, N.W.5
-
3
-
-
47649116873
-
Nogo-A expression after focal ischemic stroke in the adult rat
-
Cheatwood J.L., Emerick A.J., Schwab M.E., Kartje G.L. Nogo-A expression after focal ischemic stroke in the adult rat. Stroke 2008, 39:2091-2098.
-
(2008)
Stroke
, vol.39
, pp. 2091-2098
-
-
Cheatwood, J.L.1
Emerick, A.J.2
Schwab, M.E.3
Kartje, G.L.4
-
4
-
-
18844434370
-
Oxidative stress in the brain: novel cellular targets that govern survival during neurodegenerative disease
-
Chong Z.Z., Li F., Maiese K. Oxidative stress in the brain: novel cellular targets that govern survival during neurodegenerative disease. Prog. Neurobiol. 2005, 75:207-246.
-
(2005)
Prog. Neurobiol.
, vol.75
, pp. 207-246
-
-
Chong, Z.Z.1
Li, F.2
Maiese, K.3
-
5
-
-
0027686249
-
Oxidative stress, glutamate, and neurodegenerative disorders
-
Coyle J.T., Puttfarcken P. Oxidative stress, glutamate, and neurodegenerative disorders. Science 1993, 262:689-695.
-
(1993)
Science
, vol.262
, pp. 689-695
-
-
Coyle, J.T.1
Puttfarcken, P.2
-
6
-
-
77949913306
-
Neuroprotection of early and short-time applying atorvastatin in the acute phase of cerebral ischemia: down-regulated 12/15-LOX, p38MAPK and cPLA2 expression, ameliorated BBB permeability
-
Cui L., Zhang X.J., Yang R., Wang L.N., Liu L., Li M., Du W. Neuroprotection of early and short-time applying atorvastatin in the acute phase of cerebral ischemia: down-regulated 12/15-LOX, p38MAPK and cPLA2 expression, ameliorated BBB permeability. Brain Res. 2010, 1325:164-173.
-
(2010)
Brain Res.
, vol.1325
, pp. 164-173
-
-
Cui, L.1
Zhang, X.J.2
Yang, R.3
Wang, L.N.4
Liu, L.5
Li, M.6
Du, W.7
-
7
-
-
2142712607
-
Inflammation in stroke: the good, the bad, and the unknown
-
Dirnagl U. Inflammation in stroke: the good, the bad, and the unknown. Ernst Schering Res. Found. Workshop 2004, 47:87-99.
-
(2004)
Ernst Schering Res. Found. Workshop
, vol.47
, pp. 87-99
-
-
Dirnagl, U.1
-
8
-
-
43049135853
-
-
Donnan G.A., Fisher M., Macleod M., Davis S.M. Stroke Lancet 2008, 371:1612-1623.
-
(2008)
Stroke Lancet
, vol.371
, pp. 1612-1623
-
-
Donnan, G.A.1
Fisher, M.2
Macleod, M.3
Davis, S.M.4
-
9
-
-
27844497945
-
FOXO transcription factors at the interface between longevity and tumor suppression
-
Greer E.L., Brunet A. FOXO transcription factors at the interface between longevity and tumor suppression. Oncogene 2005, 24:7410-7425.
-
(2005)
Oncogene
, vol.24
, pp. 7410-7425
-
-
Greer, E.L.1
Brunet, A.2
-
10
-
-
34548289502
-
Dynamic FoxO transcription factors
-
Huang H., Tindall D.J. Dynamic FoxO transcription factors. J. Cell Sci. 2007, 120:2479-2487.
-
(2007)
J. Cell Sci.
, vol.120
, pp. 2479-2487
-
-
Huang, H.1
Tindall, D.J.2
-
11
-
-
0038073076
-
Antioxidant nutrients and hypoxia/ischemia brain injury in rodents
-
Ikeda K., Negishi H., Yamori Y. Antioxidant nutrients and hypoxia/ischemia brain injury in rodents. Toxicology 2003, 189:55-61.
-
(2003)
Toxicology
, vol.189
, pp. 55-61
-
-
Ikeda, K.1
Negishi, H.2
Yamori, Y.3
-
12
-
-
0034717329
-
Transcription factor Nrf2 coordinately regulates a group of oxidative stress-inducible genes in macrophages
-
Ishii T., Itoh K., Takahashi S., Sato H., Yanagawa T., Katoh Y., Bannai S., Yamamoto M. Transcription factor Nrf2 coordinately regulates a group of oxidative stress-inducible genes in macrophages. J. Biol. Chem. 2000, 275:16023-16029.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 16023-16029
-
-
Ishii, T.1
Itoh, K.2
Takahashi, S.3
Sato, H.4
Yanagawa, T.5
Katoh, Y.6
Bannai, S.7
Yamamoto, M.8
-
13
-
-
10744231953
-
Histological evidence of redox system breakdown caused by superoxide dismutase 1 (SOD1) aggregation is common to SOD1-mutated motor neurons in humans and animal models
-
Kato S., Saeki Y., Aoki M., Nagai M., Ishigaki A., Itoyama Y., Kato M., Asayama K., Awaya A., Hirano A., Ohama E. Histological evidence of redox system breakdown caused by superoxide dismutase 1 (SOD1) aggregation is common to SOD1-mutated motor neurons in humans and animal models. Acta Neuropathol. 2004, 107:149-158.
-
(2004)
Acta Neuropathol.
, vol.107
, pp. 149-158
-
-
Kato, S.1
Saeki, Y.2
Aoki, M.3
Nagai, M.4
Ishigaki, A.5
Itoyama, Y.6
Kato, M.7
Asayama, K.8
Awaya, A.9
Hirano, A.10
Ohama, E.11
-
14
-
-
0023802468
-
Prevention of atherosclerotic progression in watanabe rabbits by probucol
-
Kita T., Nagano Y., Yokode M., Ishii K., Kume N., Narumiya S., Kawai C. Prevention of atherosclerotic progression in watanabe rabbits by probucol. Am. J. Cardiol. 1988, 62:13B-19B.
-
(1988)
Am. J. Cardiol.
, vol.62
-
-
Kita, T.1
Nagano, Y.2
Yokode, M.3
Ishii, K.4
Kume, N.5
Narumiya, S.6
Kawai, C.7
-
15
-
-
0037136563
-
Forkhead transaction factor Foxo3a protects quiescent cells from oxidative stress
-
Kops G.J., Dansen T.B., Polderman P.E., Saarloos I., Wirtz K.W., Coffer P.J., Huang T.T., Bos J.L., Medema R.H., Burgering B.M. Forkhead transaction factor Foxo3a protects quiescent cells from oxidative stress. Nature 2002, 419:316-321.
-
(2002)
Nature
, vol.419
, pp. 316-321
-
-
Kops, G.J.1
Dansen, T.B.2
Polderman, P.E.3
Saarloos, I.4
Wirtz, K.W.5
Coffer, P.J.6
Huang, T.T.7
Bos, J.L.8
Medema, R.H.9
Burgering, B.M.10
-
16
-
-
0033800718
-
Atorvastatin upregulates type III nitric oxide synthase in thrombocytes, decreases platelet activation, and protects from cerebral ischemia in normocholesterolemic mice
-
Laufs U., Gertz K., Huang P., Nickenig G., Bohm M., Dirnagl U., Endres M. Atorvastatin upregulates type III nitric oxide synthase in thrombocytes, decreases platelet activation, and protects from cerebral ischemia in normocholesterolemic mice. Stroke 2003, 1:2442-2449.
-
(2003)
Stroke
, vol.1
, pp. 2442-2449
-
-
Laufs, U.1
Gertz, K.2
Huang, P.3
Nickenig, G.4
Bohm, M.5
Dirnagl, U.6
Endres, M.7
-
17
-
-
0141621061
-
NF-E2-related factor 2 mediates neuroprotection against mitochondrial complex I inhibitors and increased concentrations of intracellular calcium in primary cortical neurons
-
Lee J.M., Shih A.Y., Murphy T.H., Johnson J.A. NF-E2-related factor 2 mediates neuroprotection against mitochondrial complex I inhibitors and increased concentrations of intracellular calcium in primary cortical neurons. J. Biol. Chem. 2003, 278:37948-37956.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 37948-37956
-
-
Lee, J.M.1
Shih, A.Y.2
Murphy, T.H.3
Johnson, J.A.4
-
18
-
-
0033789565
-
Free radical pathways in CNS injury
-
Lewen A., Matz P., Chan P.H. Free radical pathways in CNS injury. J. Neurotrauma 2000, 17:871-890.
-
(2000)
J. Neurotrauma
, vol.17
, pp. 871-890
-
-
Lewen, A.1
Matz, P.2
Chan, P.H.3
-
19
-
-
0032845121
-
Ischemic cell death in brain neurons
-
Lipton P. Ischemic cell death in brain neurons. Physiol. Rev. 1999, 79:1431-1568.
-
(1999)
Physiol. Rev.
, vol.79
, pp. 1431-1568
-
-
Lipton, P.1
-
20
-
-
66849113326
-
Nipradilol and timolol induce Foxo3a and peroxiredoxin 2 expression and protect trabecular meshwork cells from oxidative stress
-
Miyamoto N., Izumi H., Miyamoto R., Kubota T., Tawara A., Sasaguri Y., Kohno K. Nipradilol and timolol induce Foxo3a and peroxiredoxin 2 expression and protect trabecular meshwork cells from oxidative stress. Invest. Ophthalmol. Vis. Sci. 2009, 50:2777-2784.
-
(2009)
Invest. Ophthalmol. Vis. Sci.
, vol.50
, pp. 2777-2784
-
-
Miyamoto, N.1
Izumi, H.2
Miyamoto, R.3
Kubota, T.4
Tawara, A.5
Sasaguri, Y.6
Kohno, K.7
-
21
-
-
0024841860
-
Antioxidant treatment of diabetic rat inhibits lipoprotein oxidation and cytotoxicity
-
Morel D.W., Chisolm G.M. Antioxidant treatment of diabetic rat inhibits lipoprotein oxidation and cytotoxicity. J. Lipid Res. 1989, 30:1827-1834.
-
(1989)
J. Lipid Res.
, vol.30
, pp. 1827-1834
-
-
Morel, D.W.1
Chisolm, G.M.2
-
22
-
-
0037192473
-
Redox regulation of forkhead proteins through a p66shc-dependent signaling pathway
-
Nemoto S., Finkel T. Redox regulation of forkhead proteins through a p66shc-dependent signaling pathway. Science 2002, 295:2450-2452.
-
(2002)
Science
, vol.295
, pp. 2450-2452
-
-
Nemoto, S.1
Finkel, T.2
-
23
-
-
33644818304
-
1026 experimental treatments in acute stroke
-
O'Collins V.E., Macleod M.R., Donnan G.A., Horky L.L., van der Worp B.H., Howells D.W. 1026 experimental treatments in acute stroke. Ann. Neurol. 2006, 59:467-477.
-
(2006)
Ann. Neurol.
, vol.59
, pp. 467-477
-
-
O'Collins, V.E.1
Macleod, M.R.2
Donnan, G.A.3
Horky, L.L.4
van der Worp, B.H.5
Howells, D.W.6
-
24
-
-
34250897267
-
Role of Cdk5-mediated phosphorylation of Prx2 in MPTP toxicity and Parkinson's disease
-
Qu D., Rashidian J., Mount M.P., Aleyasin H., Parsanejad M., Lira A., Haque E., Zhang Y., Callaghan S., Daigle M., Rousseaux M.W., Slack R.S., Albert P.R., Vincent I., Woulfe J.M., Park D.S. Role of Cdk5-mediated phosphorylation of Prx2 in MPTP toxicity and Parkinson's disease. Neuron 2007, 55:37-52.
-
(2007)
Neuron
, vol.55
, pp. 37-52
-
-
Qu, D.1
Rashidian, J.2
Mount, M.P.3
Aleyasin, H.4
Parsanejad, M.5
Lira, A.6
Haque, E.7
Zhang, Y.8
Callaghan, S.9
Daigle, M.10
Rousseaux, M.W.11
Slack, R.S.12
Albert, P.R.13
Vincent, I.14
Woulfe, J.M.15
Park, D.S.16
-
25
-
-
70349868418
-
Essential role of cytoplasmic cdk5 and Prx2 in multiple ischemic injury models, in vivo
-
Rashidian J., Rousseaux M.W., Venderova K., Qu D., Callaghan S.M., Phillips M., Bland R.J., During M.J., Mao Z., Slack R.S., Park D.S. Essential role of cytoplasmic cdk5 and Prx2 in multiple ischemic injury models, in vivo. J. Neurosci. 2009, 29:12497-12505.
-
(2009)
J. Neurosci.
, vol.29
, pp. 12497-12505
-
-
Rashidian, J.1
Rousseaux, M.W.2
Venderova, K.3
Qu, D.4
Callaghan, S.M.5
Phillips, M.6
Bland, R.J.7
During, M.J.8
Mao, Z.9
Slack, R.S.10
Park, D.S.11
-
26
-
-
0037996661
-
Coordinate regulation of glutathione biosynthesis and release by Nrf2-expressing glia potently protects neurons from oxidative stress
-
Shih A.Y., Johnson D.A., Wong G., Kraft A.D., Jiang L., Erb H., Johnson J.A., Murphy T.H. Coordinate regulation of glutathione biosynthesis and release by Nrf2-expressing glia potently protects neurons from oxidative stress. J. Neurosci. 2003, 23:3394-3406.
-
(2003)
J. Neurosci.
, vol.23
, pp. 3394-3406
-
-
Shih, A.Y.1
Johnson, D.A.2
Wong, G.3
Kraft, A.D.4
Jiang, L.5
Erb, H.6
Johnson, J.A.7
Murphy, T.H.8
-
27
-
-
20344382855
-
Polyphenols in cerebral ischemia: novel targets for neuroprotection
-
Simonyi A., Wang Q., Miller R.L., Yusof M., Shelat P.B., Sun A.Y., Sun G.Y. Polyphenols in cerebral ischemia: novel targets for neuroprotection. Mol. Neurobiol. 2005, 31:135-147.
-
(2005)
Mol. Neurobiol.
, vol.31
, pp. 135-147
-
-
Simonyi, A.1
Wang, Q.2
Miller, R.L.3
Yusof, M.4
Shelat, P.B.5
Sun, A.Y.6
Sun, G.Y.7
-
28
-
-
34547895946
-
Probucol promotes endogenous antioxidant reserve and confers protection against reperfusion injury
-
Singla D.K., Kaur K., Sharma A.K., Dhingra S., Singal P.K. Probucol promotes endogenous antioxidant reserve and confers protection against reperfusion injury. Can. J. Physiol. Pharmacol. 2007, 85:439-443.
-
(2007)
Can. J. Physiol. Pharmacol.
, vol.85
, pp. 439-443
-
-
Singla, D.K.1
Kaur, K.2
Sharma, A.K.3
Dhingra, S.4
Singal, P.K.5
-
29
-
-
0037134040
-
DNA repair pathway stimulated by the forkhead transcription factor Foxo3a through the Gadd45 protein
-
Tran H., Brunet A., Grenier J.M., Datta S.R., Fornace A.J., DiStefano P.S., Chiang L.W., Greenberg M.E. DNA repair pathway stimulated by the forkhead transcription factor Foxo3a through the Gadd45 protein. Science 2002, 296:530-534.
-
(2002)
Science
, vol.296
, pp. 530-534
-
-
Tran, H.1
Brunet, A.2
Grenier, J.M.3
Datta, S.R.4
Fornace, A.J.5
DiStefano, P.S.6
Chiang, L.W.7
Greenberg, M.E.8
-
30
-
-
34250211138
-
Myocardial ischemia reperfusion injury, antioxidant enzyme systems, and selenium
-
Venardos K.M., Perkins A., Headrick J., Kaye D.M. Myocardial ischemia reperfusion injury, antioxidant enzyme systems, and selenium. Curr. Med. Chem. 2007, 14:1539-1549.
-
(2007)
Curr. Med. Chem.
, vol.14
, pp. 1539-1549
-
-
Venardos, K.M.1
Perkins, A.2
Headrick, J.3
Kaye, D.M.4
-
31
-
-
34250630954
-
Simvastatin and atorvastatin improve behavioral outcome, reduce hippocampal degeneration, and improve cerebral blood flow after experimental traumatic brain injury
-
Wang H., Lynch J.R., Song P., Yang H.J., Yates R.B., Mace B., Warner D.S., Guyton J.R., Laskowitz D.T. Simvastatin and atorvastatin improve behavioral outcome, reduce hippocampal degeneration, and improve cerebral blood flow after experimental traumatic brain injury. Exp. Neurol. 2007, 206:59-69.
-
(2007)
Exp. Neurol.
, vol.206
, pp. 59-69
-
-
Wang, H.1
Lynch, J.R.2
Song, P.3
Yang, H.J.4
Yates, R.B.5
Mace, B.6
Warner, D.S.7
Guyton, J.R.8
Laskowitz, D.T.9
-
32
-
-
76749167941
-
Atorvastatin protects rat brains against permanent focal ischemia and downregulates HMGB1, HMGB1 receptors (RAGE and TLR4), NF-κB expression
-
Wang L.N., Zhang X.J., Liu L., Yang R., Cui L., Li M. Atorvastatin protects rat brains against permanent focal ischemia and downregulates HMGB1, HMGB1 receptors (RAGE and TLR4), NF-κB expression. Neurosci. Lett. 2010, 471:152-156.
-
(2010)
Neurosci. Lett.
, vol.471
, pp. 152-156
-
-
Wang, L.N.1
Zhang, X.J.2
Liu, L.3
Yang, R.4
Cui, L.5
Li, M.6
-
33
-
-
0029082801
-
Possible function of SP-22, a substrate of mitochondrial ATP-dependent protease, as a radical scavenger
-
Watabe S., Hasegawa H., Takimoto K., Yamamoto Y., Takahashi S.Y. Possible function of SP-22, a substrate of mitochondrial ATP-dependent protease, as a radical scavenger. Biochem. Biophys. Res. Commun. 1995, 213:1010-1016.
-
(1995)
Biochem. Biophys. Res. Commun.
, vol.213
, pp. 1010-1016
-
-
Watabe, S.1
Hasegawa, H.2
Takimoto, K.3
Yamamoto, Y.4
Takahashi, S.Y.5
|