High glucose enhances TGF-β1 expression in rat bone marrow stem cells via ERK1/2-mediated inhibition of STAT3 signaling

Life Sciences

Volumn 90, Issue 13-14, 2012, Pages 509-518

  Luo, Min ^a,b   Liu, Zehao ^a,b   Chen, Guohua ^b   Hao, Hong ^b   Lu, Tiewei ^b   Cui, Yuqi ^b   Lei, Minxiang ^a   Verfaillie, Catherine M ^c   Liu, Zhenguo ^b  

^a CENTRAL SOUTH UNIVERSITY   (China)

^b OHIO STATE UNIVERSITY   (United States)

^c UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

Author keywords

Bone marrow stem cell; ERK1 2; High glucose; STAT3; TGF 1

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; GLUCOSE; LEVO GLUCOSE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; OCTAMER TRANSCRIPTION FACTOR 4; SERINE; STAT3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA1; TYROSINE;

ANIMAL CELL; ANIMAL CELL CULTURE; ARTICLE; BONE MARROW MULTIPOTENT ADULT PROGENITOR CELL; CELL PROLIFERATION; CONTROLLED STUDY; CULTURE MEDIUM; ENZYME ACTIVATION; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME PHOSPHORYLATION; GENE EXPRESSION REGULATION; GENE INDUCTION; HEMATOPOIETIC STEM CELL; IMMUNOFLUORESCENCE; MULTIPOTENT STEM CELL; NONHUMAN; OSMOLARITY; PROTEIN EXPRESSION; PROTEIN INDUCTION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION;

ANIMALS; BONE MARROW CELLS; CELLS, CULTURED; GLUCOSE; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MULTIPOTENT STEM CELLS; RATS; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR; TRANSFORMING GROWTH FACTOR BETA1;

RATTUS;

EID: 84862789112     PISSN: 00243205     EISSN: 18790631     Source Type: Journal    
DOI: 10.1016/j.lfs.2012.01.005     Document Type: Article

References (59)

1. O. Agbulut, M. Mazo, C. Bressolle, M. Gutierrez, K. Azarnoush, and L. Sabbah Can bone marrow-derived multipotent adult progenitor cells regenerate infarcted myocardium? Cardiovasc Res 72 2006 175 183 (Pubitemid 44321918)
2. X.L. Aranguren, J.D. McCue, B. Hendrickx, X.H. Zhu, F. Du, and E. Chen Multipotent adult progenitor cells sustain function of ischemic limbs in mice J Clin Invest 118 2008 505 514 (Pubitemid 351206541)
3. S. Belmadani, M. Zerfaoui, H.A. Boulares, D.I. Palen, and K. Matrougui Microvessel vascular smooth muscle cells contribute to collagen type I deposition through ERK1/2 MAP kinase, alphavbeta3-integrin, and TGF-beta1 in response to ANG II and high glucose Am J Physiol Heart Circ Physiol 295 2008 H69 H76
4. Y.H. Chen, J.Y. Guh, T.D. Chuang, H.C. Chen, S.J. Chiou, and J.S. Huang High glucose decreases endothelial cell proliferation via the extracellular signal regulated kinase/p15(INK4b) pathway Arch Biochem Biophys 465 2007 164 171
5. L. Chen, E.E. Tredget, P.Y. Wu, and Y. Wu Paracrine factors of mesenchymal stem cells recruit macrophages and endothelial lineage cells and enhance wound healing PLoS One 3 2008 e1886
6. J. Chung, E. Uchida, T.C. Grammer, and J. Blenis STAT3 serine phosphorylation by ERK-dependent and -independent pathways negatively modulates its tyrosine phosphorylation Mol Cell Biol 17 1997 6508 6516 (Pubitemid 27451197)
7. B.D. Cook, G. Ferrari, G. Pintucci, and P. Mignatti TGF-beta1 induces rearrangement of FLK-1-VE-cadherin-beta-catenin complex at the adherens junction through VEGF-mediated signaling J Cell Biochem 105 2008 1367 1373
8. K.M. Dhandapani, M.M. Khan, F.M. Wade, C. Wakade, V.B. Mahesh, and D.W. Brann Induction of transforming growth factor-beta1 by basic fibroblast growth factor in rat C6 glioma cells and astrocytes is mediated by MEK/ERK signaling and AP-1 activation J Neurosci Res 85 2007 1033 1045 (Pubitemid 46580344)
9. M.M. Engelgau, L.S. Geiss, J.B. Saaddine, J.P. Boyle, S.M. Benjamin, and E.W. Gregg The evolving diabetes burden in the United States Ann Intern Med 140 2004 945 950 (Pubitemid 38685285)
10. G. Ferrari, G. Pintucci, G. Seghezzi, K. Hyman, A.C. Galloway, and P. Mignatti VEGF, a prosurvival factor, acts in concert with TGF-beta1 to induce endothelial cell apoptosis Proc Natl Acad Sci U S A 103 2006 17260 17265 (Pubitemid 44788957)
11. G. Ferrari, B.D. Cook, V. Terushkin, G. Pintucci, and P. Mignatti Transforming growth factor-beta 1 (TGF-beta1) induces angiogenesis through vascular endothelial growth factor (VEGF)-mediated apoptosis J Cell Physiol 219 2009 449 458
12. M.A. Frias, R.W. James, C. Gerber-Wicht, and U. Lang Native and reconstituted HDL activate Stat3 in ventricular cardiomyocytes via ERK1/2: role of sphingosine-1-phosphate Cardiovasc Res 82 2009 313 323
13. H. Fujita, S. Omori, K. Ishikura, M. Hida, and M. Awazu ERK and p38 mediate high-glucose-induced hypertrophy and TGF-beta expression in renal tubular cells Am J Physiol Renal Physiol 286 2004 F120 F126
14. M. Giannopoulou, S.C. Iszkula, C. Dai, X. Tan, J. Yang, and G.K. Michalopoulos Distinctive role of Stat3 and Erk-1/2 activation in mediating interferon-gamma inhibition of TGF-beta1 action Am J Physiol Renal Physiol 290 2006 F1234 F1240
15. M.J. Goumans, Z. Liu, and P. ten Dijke TGF-beta signaling in vascular biology and dysfunction Cell Res 19 2009 116 127
16. D.J. Grainger TGF-beta and atherosclerosis in man Cardiovasc Res 74 2007 213 222
17. D. Gramatzki, G. Pantazis, J. Schittenhelm, G. Tabatabai, C. Kohle, and W. Wick Aryl hydrocarbon receptor inhibition downregulates the TGF-beta/Smad pathway in human glioblastoma cells Oncogene 28 2009 2593 2605
18. G.H. Guo, D.M. Tan, P.A. Zhu, and F. Liu Hepatitis B virus X protein promotes proliferation and upregulates TGF-beta1 and CTGF in human hepatic stellate cell line, LX-2 Hepatobiliary Pancreat Dis Int 8 2009 59 64
19. H. Ha, and H.B. Lee Reactive oxygen species as glucose signaling molecules in mesangial cells cultured under high glucose Kidney Int Suppl 77 2000 S19 S25
20. J.S. Han, B.S. Choi, C.W. Yang, and Y.S. Kim Aldosterone-induced TGF-beta1 expression is regulated by mitogen-activated protein kinases and activator protein-1 in mesangial cells J Korean Med Sci 24 2009 S195 S203 Suppl.
21. T. Hayashida, and H.W. Schnaper High ambient glucose enhances sensitivity to TGF-beta1 via extracellular signal-regulated kinase and protein kinase C delta activities in human mesangial cells J Am Soc Nephrol 15 2004 2032 2041 (Pubitemid 39031342)
22. J.G. He, Y.L. Chen, B.L. Chen, Y.Y. Huang, F.J. Yao, and S.L. Chen B-type natriuretic peptide attenuates cardiac hypertrophy via TGF-beta1/smad7 pathway in vivo and in vitro Clin Exp Pharmacol Physiol 37 2010 283 289
23. C. Heeschen, R. Lehmann, J. Honold, B. Assmus, A. Aicher, and D.H. Walter Profoundly reduced neovascularization capacity of bone marrow mononuclear cells derived from patients with chronic ischemic heart disease Circulation 109 2004 1615 1622 (Pubitemid 38451717)
24. M. Ii, H. Takenaka, J. Asai, K. Ibusuki, Y. Mizukami, and K. Maruyama Endothelial progenitor thrombospondin-1 mediates diabetes-induced delay in reendothelialization following arterial injury Circ Res 98 2006 697 704
25. M.L. Iruela-Arispe, and E.H. Sage Endothelial cells exhibiting angiogenesis in vitro proliferate in response to TGF-beta 1 J Cell Biochem 52 1993 414 430 (Pubitemid 23258129)
26. M. Isono, M.C. Cruz, S. Chen, S.W. Hong, and F.N. Ziyadeh Extracellular signal-regulated kinase mediates stimulation of TGF-beta1 and matrix by high glucose in mesangial cells J Am Soc Nephrol 11 2000 2222 2230
27. S.H. Jeon, B.C. Chae, H.A. Kim, G.Y. Seo, D.W. Seo, and G.T. Chun Mechanisms underlying TGF-beta1-induced expression of VEGF and Flk-1 in mouse macrophages and their implications for angiogenesis J Leukoc Biol 81 2007 557 566
28. Y. Jiang, B.N. Jahagirdar, R.L. Reinhardt, R.E. Schwartz, C.D. Keene, and X.R. Ortiz-Gonzalez Pluripotency of mesenchymal stem cells derived from adult marrow Nature 418 2002 41 49 (Pubitemid 34742565)
29. Y. Jiang, B. Vaessen, T. Lenvik, M. Blackstad, M. Reyes, and C.M. Verfaillie Multipotent progenitor cells can be isolated from postnatal murine bone marrow, muscle, and brain Exp Hematol 30 2002 896 904 (Pubitemid 34845893)
30. M.H. Jin, C.H. Hong, H.Y. Lee, H.J. Kang, and S.W. Han Enhanced TGF-beta1 is involved in 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) induced oxidative stress in C57BL/6 mouse testis Toxicol Lett 178 2008 202 209
31. Y.S. Kim, D.H. Jung, N.H. Kim, Y.M. Lee, and J.S. Kim Effect of magnolol on TGF-beta1 and fibronectin expression in human retinal pigment epithelial cells under diabetic conditions Eur J Pharmacol 562 2007 12 19 (Pubitemid 46466755)
32. S.M. Kim, N. Kim, S. Lee, K. Kim do, Y.M. Lee, S.H. Ahn, J.H. Song, B.K. Choi, C. Wu, and K.Y. Jung TGF-beta1-induced PINCH-1-ILK-alpha-parvin complex formation regulates mesangial cell proliferation and hypertrophy Exp Mol Med 39 2007 514 523 (Pubitemid 47443866)
33. T. Kinnaird, E. Stabile, S. Zbinden, M.S. Burnett, and S.E. Epstein Cardiovascular risk factors impair native collateral development and may impair efficacy of therapeutic interventions Cardiovasc Res 78 2008 257 264 (Pubitemid 351556098)
34. N. Kränkel, V. Adams, A. Linke, S. Gielen, S. Erbs, and K. Lenk Hyperglycemia reduces survival and impairs function of circulating blood-derived progenitor cells Arterioscler Thromb Vasc Biol 25 2005 698 703 (Pubitemid 40463856)
35. Y.K. Lee, E.J. Kim, J.E. Lee, J.W. Noh, and Y.G. Kim Hypoxia induces connective tissue growth factor mRNA expression J Korean Med Sci 24 2009 S176 S182 Suppl.
36. D. Li, C. Zhang, F. Song, I. Lubenec, Y. Tian, and Q.H. Song VEGF regulates FGF-2 and TGF-beta1 expression in injury endothelial cells and mediates smooth muscle cells proliferation and migration Microvasc Res 77 2009 134 142
37. Z. Liu, M. Lei, Y. Jiang, H. Hao, L. Chu, and J. Xu High glucose attenuates VEGF expression in rat multipotent adult progenitor cells in association with inhibition of JAK2/STAT3 signaling J Cell Mol Med 13 2008 3427 3436
38. C.J. Loomans, E.J. de Koning, F.J. Staal, M.B. Rookmaaker, C. Verseyden, and H.C. de Boer Endothelial progenitor cell dysfunction: a novel concept in the pathogenesis of vascular complications of type 1 diabetes Diabetes 53 2004 195 199 (Pubitemid 38044715)
39. T. Lu, B. Pelacho, H. Hao, M. Luo, J. Zhu, and C.M. Verfaillie Cardiomyocyte differentiation of rat bone marrow multipotent progenitor cells is associated with downregulation of Oct-4 expression Tissue Eng Part A 16 2010 3111 3117
40. M. Mirotsou, T.M. Jayawardena, J. Schmeckpeper, M. Gnecchi, and V.J. Dzau Paracrine mechanisms of stem cell reparative and regenerative actions in the heart J Mol Cell Cardiol 50 2011 280 289
41. G. Niu, K.L. Wright, M. Huang, L. Song, E. Haura, and J. Turkson Constitutive Stat3 activity up-regulates VEGF expression and tumor angiogenesis Oncogene 21 2002 2000 2008 (Pubitemid 34270888)
42. H. Ogata, T. Chinen, T. Yoshida, I. Kinjyo, G. Takaesu, and H. Shiraishi Loss of SOCS3 in the liver promotes fibrosis by enhancing STAT3-mediated TGF-beta1 production Oncogene 25 2006 2520 2530
43. B. Pelacho, Y. Nakamura, J. Zhang, J. Ross, Y. Heremans, and M. Nelson-Holte Multipotent adult progenitor cell transplantation increases vascularity and improves left ventricular function after myocardial infarction J Tissue Eng Regen Med 1 2007 51 59
44. S. Redondo, E. Ruiz, E. Padilla, A. Gordillo-Moscoso, and T. Tejerina Role of TGF-beta1 in vascular smooth muscle cell apoptosis induced by angiotensin II Eur J Pharmacol 556 2007 36 44 (Pubitemid 46074003)
45. S. Rosenkranz TGF-beta1 and angiotensin networking in cardiac remodeling Cardiovasc Res 63 2004 423 432 (Pubitemid 38970186)
46. J.M. Ryu, M.Y. Lee, S.P. Yun, and H.J. Han High glucose regulates cyclin D1/E of human mesenchymal stem cells through TGF-beta1 expression via Ca2+/PKC/MAPKs and PI3K/Akt/mTOR signal pathways J Cell Physiol 224 2010 59 70
47. B. Schmierer, and C.S. Hill TGFbeta-SMAD signal transduction: molecular specificity and functional flexibility Nat Rev Mol Cell Biol 8 2007 970 982 (Pubitemid 350174642)
48. N.R. Sodha, R.T. Clements, M. Boodhwani, S.H. Xu, R.J. Laham, and C. Bianchi Endostatin and angiostatin are increased in diabetic patients with coronary artery disease and associated with impaired coronary collateral formation Am J Physiol Heart Circ Physiol 296 2009 H428 H434
49. D.E. Sullivan, M. Ferris, D. Pociask, and A.R. Brody The latent form of TGFbeta(1) is induced by TNFalpha through an ERK specific pathway and is activated by asbestos-derived reactive oxygen species in vitro and in vivo J Immunotoxicol 5 2008 145 149 (Pubitemid 351882416)
50. O.M. Tepper, R.D. Galiano, J.M. Capla, C. Kalka, P.J. Gagne, and G.R. Jacobowitz Human endothelial progenitor cells from type II diabetics exhibit impaired proliferation, adhesion, and incorporation into vascular structures Circulation 106 2002 2781 2786 (Pubitemid 35396976)
51. F. Ulloa-Montoya, B.L. Kidder, K.A. Pauwelyn, L.G. Chase, A. Luttun, and A. Crabbe Comparative transcriptome analysis of embryonic and adult stem cells with extended and limited differentiation capacity Genome Biol 8 2007 R163
52. F. Vinals, and J. Pouyssegur Transforming growth factor beta1 (TGF-beta1) promotes endothelial cell survival during in vitro angiogenesis via an autocrine mechanism implicating TGF-alpha signaling Mol Cell Biol 21 2001 7218 7230 (Pubitemid 32953476)
53. M. Wang, W. Zhang, P. Crisostomo, T. Markel, K.K. Meldrum, and X.Y. Fu STAT3 mediates bone marrow mesenchymal stem cell VEGF production J Mol Cell Cardiol 42 2007 1009 1015 (Pubitemid 46829204)
54. B.R. Weil, A.M. Abarbanell, J.L. Herrmann, Y. Wang, and D.R. Meldrum High glucose concentration in cell culture medium does not acutely affect human mesenchymal stem cell growth factor production or proliferation Am J Physiol Regul Integr Comp Physiol 296 2009 R1735 R1743
55. A.T. Wierenga, J.J. Schuringa, B.J. Eggen, W. Kruijer, and E. Vellenga Downregulation of IL-6-induced STAT3 tyrosine phosphorylation by TGF-beta1 is mediated by caspase-dependent and -independent processes Leukemia 16 2002 675 682 (Pubitemid 34449750)
56. A.R. Williams, and J.M. Hare Mesenchymal stem cells: biology, pathophysiology, translational findings, and therapeutic implications for cardiac disease Circ Res 109 2011 923 940
57. A.A. Worster, A.J. Nixon, B.D. Brower-Toland, and J. Williams Effect of transforming growth factor beta1 on chondrogenic differentiation of cultured equine mesenchymal stem cells Am J Vet Res 61 2000 1003 1010
58. D. Wu, F. Peng, B. Zhang, A.J. Ingram, D.J. Kelly, and R.E. Gilbert PKC-beta1 mediates glucose-induced Akt activation and TGF-beta1 upregulation in mesangial cells J Am Soc Nephrol 20 2009 554 566
59. J.H. Yu, K.H. Kim, and H. Kim SOCS 3 and PPAR-gamma ligands inhibit the expression of IL-6 and TGF-beta1 by regulating JAK2/STAT3 signaling in pancreas Int J Biochem Cell Biol 40 2008 677 688 (Pubitemid 351297741)