Myoglobin-Induced Apoptosis: Two Pathways Related to Endoplasmic Reticulum Stress

Therapeutic Apheresis and Dialysis

Volumn 16, Issue 3, 2012, Pages 272-280

  Zhou, Jianhui ^a   Kong, Deyang ^a,b   Zhang, Xu ^a,c   Wang, Yuanda ^a   Feng, Zhe ^a   Zhang, Xueguang ^a   Zhang, Li ^a   Wang, Yan ^d   Xie, Yuansheng ^a   Chen, Xiangmei ^a  

^a CHINESE PLA GENERAL HOSPITAL   (China)

^b THE FIRST AFFILIATED HOSPITAL OF HARBIN MEDICAL UNIVERSITY   (China)

^c DALIAN MEDICAL UNIVERSITY   (China)

^d HEBEI MEDICAL UNIVERSITY   (China)

Author keywords

Acute kidney injury; Apoptosis; Myoglobin; Rhabdomyolysis

Indexed keywords

2 AMINOETHOXYDIPHENYLBORANE; 3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; BETA ACTIN; CASPASE 3; CASPASE 4; CASPASE 9; CYTOCHROME C; METMYOGLOBIN; MYOGLOBIN;

ACUTE KIDNEY FAILURE; APOPTOSIS; ARTICLE; CELL DAMAGE; CELL VIABILITY; ENDOPLASMIC RETICULUM STRESS; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; HUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RHABDOMYOLYSIS;

ACUTE KIDNEY INJURY; APOPTOSIS; BLOTTING, WESTERN; CASPASES; CELL SURVIVAL; CELLS, CULTURED; ENDOPLASMIC RETICULUM STRESS; FLOW CYTOMETRY; HUMANS; LACTOSE; MICROSCOPY, FLUORESCENCE; MYOGLOBIN; SIGNAL TRANSDUCTION; TETRAZOLIUM SALTS; THIAZOLES;

EID: 84862787959     PISSN: 17449979     EISSN: 17449987     Source Type: Journal    
DOI: 10.1111/j.1744-9987.2011.01057.x     Document Type: Article

References (46)

1. Bosch X, Poch E, Grau JM. Rhabdomyolysis and acute kidney injury. N Engl J Med 2009;361:62-72.
2. Riedl SJ, Salvesen GS. The apoptosome: signalling platform of cell death. Nat Rev Mol Cell Biol 2007;8:405-13.
3. Price PM, Safirstein RL, Megyesi J. The cell cycle and acute kidney injury. Kidney Int 2009;76:604-13.
4. Hotchkiss RS, Strasser A, McDunn JE, Swanson PE. Cell death. N Engl J Med 2009;361:1570-83.
5. Jin QH, Zhao B, Zhang XJ. Cytochrome c release and endoplasmic reticulum stress are involved in caspase-dependent apoptosis induced by G418. Cell Mol Life Sci 2004;61:1816-25.
6. Li Z, Zhang T, Dai H etal. Endoplasmic reticulum stress is involved in myocardial apoptosis of streptozocin-induced diabetic rats. J Endocrinol 2008;196:565-72.
7. Zager RA, Burkhart K. Myoglobin toxicity in proximal human kidney cells: roles of Fe, Ca2+, H2O2, and terminal mitochondrial electron transport. Kidney Int 1997;51:728-38.
8. Zager RA, Foerder CA. Effects of inorganic iron and myoglobin on in vitro proximal tubular lipid peroxidation and cytotoxicity. J Clin Invest 1992;89:989-95.
9. Iwata M, Zager RA. Myoglobin inhibits proliferation of cultured human proximal tubular (HK-2) cells. Kidney Int 1996;50:796-804.
10. Valentovic MA, Minigh J. Pyruvate attenuates myoglobin in vitro toxicity. Toxicol Sci 2003;74:345-51.
11. Minigh JL, Valentovic MA. Characterization of myoglobin toxicity in renal cortical slices from Fischer 344 rats. Toxicology 2003;184:113-23.
12. Lorz C, Benito-Martin A, Justo P etal. Modulation of renal tubular cell survival: where is the evidence. Curr Med Chem 2006;13:449-54.
13. Green DR, Kroemer G. Pharmacological manipulation of cell death: clinical applications in sight. J Clin Invest 2005;115:2610-17.
14. Ellis HM, Horvitz HR. Genetic control of programmed cell death in the nematode C. elegans. Cell 1986;44:817-29.
15. Thornberry NA, Lazebnik Y. Caspases: enemies within. Science 1998;281:1312-16.
16. Danial NN, Korsmeyer SJ. Cell death: critical control points. Cell 2004;116:205-19.
17. Li P, Nijhawan D, Budihardjo I etal. Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade. Cell 1997;91:479-89.
18. Szegezdi E, Logue SE, Gorman AM, Samali A. Mediators of endoplasmic reticulum stress-induced apoptosis. EMBO Rep 2006;7:880-5.
19. Groenendyk J, Michalak M. Endoplasmic reticulum quality control and apoptosis. Acta Biochim Pol 2005;52:381-95.
20. Schroder M, Kaufman RJ. The mammalian unfolded protein response. Annu Rev Biochem 2005;74:739-89.
21. Nakagawa T, Zhu H, Morishima N etal. Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta. Nature 2000;403:98-103.
22. Yoneda T, Imaizumi K, Oono K etal. Activation of caspase-12, an endoplastic reticulum (ER) resident caspase, through tumor necrosis factor receptor-associated factor 2-dependent mechanism in response to the ER stress. J Biol Chem 2001;276:13935-40.
23. Larner SF, Hayes RL, Wang KK. Unfolded protein response after neurotrauma. J Neurotrauma 2006;23:807-29.
24. Nakagawa T, Yuan J. Cross-talk between two cysteine protease families. Activation of caspase-12 by calpain in apoptosis. J Cell Biol 2000;150:887-94.
25. Saleh M, Vaillancourt JP, Graham RK etal. Differential modulation of endotoxin responsiveness by human caspase-12 polymorphisms. Nature 2004;429:75-9.
26. Matsuzaki S, Hiratsuka T, Kuwahara R, Katayama T, Tohyama M. Caspase-4 is partially cleaved by calpain via the impairment of Ca2+ homeostasis under the ER stress. Neurochem Int 2010;56:352-6.
27. Kim SJ, Zhang Z, Hitomi E, Lee YC, Mukherjee AB. Endoplasmic reticulum stress-induced caspase-4 activation mediates apoptosis and neurodegeneration in INCL. Hum Mol Genet 2006;15:1826-34.
28. Hitomi J, Katayama T, Eguchi Y etal. Involvement of caspase-4 in endoplasmic reticulum stress-induced apoptosis and Abeta-induced cell death. J Cell Biol 2004;165:347-56.
29. Rao RV, Ellerby HM, Bredesen DE. Coupling endoplasmic reticulum stress to the cell death program. Cell Death Differ 2004;11:372-80.
30. Baumgartner HK, Gerasimenko JV, Thorne C etal. Caspase-8-mediated apoptosis induced by oxidative stress is independent of the intrinsic pathway and dependent on cathepsins. Am J Physiol Gastrointest Liver Physiol 2007;293:G296-307.
31. Gerasimenko JV, Gerasimenko OV, Palejwala A, Tepikin AV, Petersen OH, Watson AJ. Menadione-induced apoptosis: roles of cytosolic Ca(2+) elevations and the mitochondrial permeability transition pore. J Cell Sci 2002;115(Pt 3): 485-97.
32. Riedl SJ, Shi Y. Molecular mechanisms of caspase regulation during apoptosis. Nat Rev Mol Cell Biol 2004;5:897-907.
33. Basu A, Castle VP, Bouziane M, Bhalla K, Haldar S. Crosstalk between extrinsic and intrinsic cell death pathways in pancreatic cancer: synergistic action of estrogen metabolite and ligands of death receptor family. Cancer Res 2006;66:4309-18.
34. Li H, Zhu H, Xu CJ, Yuan J. Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis. Cell 1998;94:491-501.
35. Di SF, Ferraro E, Tufi R, Achsel T, Piacentini M, Cecconi F. Endoplasmic reticulum stress induces apoptosis by an apoptosome-dependent but caspase 12-independent mechanism. J Biol Chem 2006;281:2693-700.
36. Obeng EA, Boise LH. Caspase-12 and caspase-4 are not required for caspase-dependent endoplasmic reticulum stress-induced apoptosis. J Biol Chem 2005;280:29578-87.
37. Masud A, Mohapatra A, Lakhani SA, Ferrandino A, Hakem R, Flavell RA. Endoplasmic reticulum stress-induced death of mouse embryonic fibroblasts requires the intrinsic pathway of apoptosis. J Biol Chem 2007;282:14132-9.
38. Morishima N, Nakanishi K, Takenouchi H, Shibata T, Yasuhiko Y. An endoplasmic reticulum stress-specific caspase cascade in apoptosis. Cytochrome c-independent activation of caspase-9 by caspase-12. J Biol Chem 2002;277:34287-94.
39. Sanz AB, Santamaria B, Ruiz-Ortega M, Egido J, Ortiz A. Mechanisms of renal apoptosis in health and disease. J Am Soc Nephrol 2008;19:1634-42.
40. Campanella M, Pinton P, Rizzuto R. Mitochondrial Ca2+ homeostasis in health and disease. Biol Res 2004;37:653-60.
41. Orrenius S, Zhivotovsky B, Nicotera P. Regulation of cell death: the calcium-apoptosis link. Nat Rev Mol Cell Biol 2003;4:552-65.
42. Kroemer G, Reed JC. Mitochondrial control of cell death. Nat Med 2000;6:513-19.
43. Martinou JC, Desagher S, Antonsson B. Cytochrome c release from mitochondria: all or nothing. Nat Cell Biol 2000;2:E41-3.
44. Van Coppenolle F, Vanden AF, Slomianny C etal. Ribosome-translocon complex mediates calcium leakage from endoplasmic reticulum stores. J Cell Sci 2004;117(Pt 18): 4135-42.
45. Lomax RB, Camello C, Van Coppenolle F, Petersen OH, Tepikin AV. Basal and physiological Ca(2+) leak from the endoplasmic reticulum of pancreatic acinar cells. Second messenger-activated channels and translocons. J Biol Chem 2002;277:26479-85.
46. Berridge MJ, Lipp P, Bootman MD. The versatility and universality of calcium signalling. Nat Rev Mol Cell Biol 2000;1:11-21.