Transgene expression and local tissue distribution of naked and polymer-condensed plasmid DNA after intradermal administration in mice

Journal of Controlled Release

Volumn 159, Issue 2, 2012, Pages 232-239

  Palumbo, R Noelle ^a   Zhong, Xiao ^a   Panus, David ^a   Han, Wenqing ^a   Ji, Weihang ^a   Wang, Chun ^a  

^a University of Minnesota   (United States)

Author keywords

Biodistribution; DNA vaccines; PEGylation; Polyplexes

Indexed keywords

ANIMAL IMAGING; ANTIGEN PRESENTING CELLS; BIODISTRIBUTIONS; CATIONIC POLYMERS; COLOCALIZATION; DENDRITIC CELLS; DERMAL FIBROBLASTS; DETECTION LIMITS; DNA VACCINATION; DNA VACCINE; IMMUNE RESPONSE; IN-VIVO; LYMPH NODE; NAKED PLASMID; PEGYLATION; PLASMID DNA; POLYMER STRUCTURE; POLYPLEXES; TIME POINTS; TISSUE DISTRIBUTIONS; TRANSGENE EXPRESSION;

BIOMOLECULES; CELL CULTURE; DNA; MAMMALS; TISSUE; VACCINES;

POLYMERS;

DNA VACCINE; LUCIFERASE; NAKED DNA; PLASMID DNA; POLYETHYLENEIMINE; POLYMER;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DENDRITIC CELL; DNA TRANSFECTION; FLUORESCENCE; GENE EXPRESSION; IN VIVO STUDY; MACROPHAGE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SKIN FIBROBLAST; TISSUE DISTRIBUTION; TRANSGENE;

ACRYLIC RESINS; ANIMALS; CATIONS; DNA; DRUG CARRIERS; DRUG STABILITY; GENE EXPRESSION; INJECTIONS, INTRADERMAL; LUCIFERASES; MALE; METHACRYLATES; MICE; MICE, INBRED C57BL; MICROSCOPY, CONFOCAL; MICROSCOPY, FLUORESCENCE; MOLECULAR STRUCTURE; PLASMIDS; POLYETHYLENE GLYCOLS; POLYETHYLENEIMINE; POLYMERS; SKIN; TISSUE DISTRIBUTION; TRANSGENES; VACCINES, DNA;

EID: 84862785818     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2012.01.012     Document Type: Article

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