The anti-fibrotic effect of betulinic acid is mediated through the inhibition of NF-κB nuclear protein translocation

Chemico-Biological Interactions

Volumn 195, Issue 3, 2012, Pages 215-223

  Wan, Ying ^a   Wu, Yan Ling ^a   Lian, Li Hua ^a   Xie, Wen Xue ^a   Li, Xin ^a   Ouyang, Bing Qing ^a   Bai, Ting ^a   Li, Qian ^a   Yang, Ning ^a   Nan, Ji Xing ^a  

^a YANBIAN UNIVERSITY   (China)

Author keywords

Betulinic acid; Hepatic fibrosis; Thioacetamide

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; BETULIC ACID; CASPASE 3; CASPASE 8; COLLAGEN TYPE 1; COLLAGENASE 3; HYDROXYPROLINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MYELOID DIFFERENTIATION FACTOR 88; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIFIBROSIS ACTIVITY; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; DRUG ACTIVITY; DRUG EFFICACY; DRUG MECHANISM; DRUG STRUCTURE; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; LIVER FIBROSIS; LIVER PROTECTION; MALE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN TRANSPORT; RAT; SIGNAL TRANSDUCTION; WISTAR RAT;

ACTINS; ANIMALS; BLOTTING, WESTERN; CELL LINE; CELL SURVIVAL; HYDROXYPROLINE; IMMUNOHISTOCHEMISTRY; LIVER CIRRHOSIS; LIVER CIRRHOSIS, EXPERIMENTAL; MALE; MATRIX METALLOPROTEINASE 13; MYELOID DIFFERENTIATION FACTOR 88; NF-KAPPA B; PROTEIN TRANSPORT; RANDOM ALLOCATION; RATS; RATS, WISTAR; THIOACETAMIDE; TISSUE INHIBITOR OF METALLOPROTEINASE-1; TOLL-LIKE RECEPTOR 4; TRITERPENES;

BETULA; BETULACEAE; RATTUS NORVEGICUS;

EID: 84862781991     PISSN: 00092797     EISSN: 18727786     Source Type: Journal    
DOI: 10.1016/j.cbi.2012.01.002     Document Type: Article

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