Betulinic acid-induced apoptosis in glioma cells: A sequential requirement for new protein synthesis, formation of reactive oxygen species, and caspase processing

Journal of Pharmacology and Experimental Therapeutics

Volumn 289, Issue 3, 1999, Pages 1306-1312

  Wick, Wolfgang ^a   Grimmel, Cornelia ^a   Wagenknecht, Bettina ^a   Dichgans, Johannes ^a   Weller, Michael ^a,b  

^a UNIVERSITY OF TÜBINGEN   (Germany)

^b UNIVERSITY HOSPITAL TÜBINGEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BETULIC ACID; CASPASE; DNA FRAGMENT; PROTEIN P21; PROTEIN P53; REACTIVE OXYGEN METABOLITE;

APOPTOSIS; ARTICLE; CELL CYCLE; CELL DEATH; CONTROLLED STUDY; CYTOTOXICITY; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME MODIFICATION; GENE EXPRESSION; GLIOMA CELL; HUMAN; HUMAN CELL; MELANOMA; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SYNTHESIS;

ANTIGENS, CD95; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BCL-X PROTEIN; CASPASES; CELL CYCLE; CELL DIVISION; CELL SURVIVAL; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLINS; CYCLOHEXIMIDE; CYSTEINE PROTEINASE INHIBITORS; DNA FRAGMENTATION; ENZYME ACTIVATION; FAS LIGAND PROTEIN; GLIOMA; HUMANS; KINETICS; MEMBRANE GLYCOPROTEINS; OLIGOPEPTIDES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; REACTIVE OXYGEN SPECIES; TRITERPENES; TUMOR CELLS, CULTURED;

EID: 0033023669     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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