Lonicera japonica THUNB. protects 6-hydroxydopamine-induced neurotoxicity by inhibiting activation of MAPKs, PI3K/Akt, and NF-κB in SH-SY5Y cells

Food and Chemical Toxicology

Volumn 50, Issue 3-4, 2012, Pages 797-807

  Kwon, Seung Hwan ^a   Hong, Sa Ik ^a   Jung, Yang Hee ^a   Kim, Min Jung ^a   Kim, Sun Yeou ^b   Kim, Hyoung Chun ^c   Lee, Seok Yong ^a   Jang, Choon Gon ^a  

^a Sungkyunkwan University   (South Korea)

^b Kyung Hee University   (South Korea)

^c Kangwon National University   (South Korea)

Author keywords

Lonicera japonica THUNB.; Mitogen activated protein kinase; Neurotoxicity; Nuclear factor B; Parkinson's disease; Phosphoinositide 3 kinase Akt

Indexed keywords

CASPASE 3; CASPASE 9; CATALASE; GLUTATHIONE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LACTATE DEHYDROGENASE; LONICERA JAPONICA EXTRACT; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 13; MITOGEN ACTIVATED PROTEIN KINASE 9; MITOGEN ACTIVATED PROTEIN KINASE P38; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE 1; SUPEROXIDE DISMUTASE;

ANTIOXIDANT ACTIVITY; ARTICLE; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA FRAGMENTATION; DOWN REGULATION; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME RELEASE; FLOWER; HUMAN; HUMAN CELL; IN VITRO STUDY; MITOCHONDRIAL MEMBRANE POTENTIAL; NEUROBLASTOMA CELL; NEUROPROTECTION; NEUROTOXICITY; OXIDATIVE STRESS; PROTEIN CLEAVAGE; PROTEIN PHOSPHORYLATION;

BLOTTING, WESTERN; CELL LINE, TUMOR; ENZYME ACTIVATION; HUMANS; IN SITU NICK-END LABELING; LONICERA; MITOGEN-ACTIVATED PROTEIN KINASES; NF-KAPPA B; OXIDOPAMINE; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT; PROTO-ONCOGENE PROTEINS C-BCL-2; REACTIVE OXYGEN SPECIES;

LONICERA JAPONICA;

EID: 84862780536     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2011.12.026     Document Type: Article

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