Artesunate induces G0/G1 cell cycle arrest and iron-mediated mitochondrial apoptosis in A431 human epidermoid carcinoma cells

Anti-Cancer Drugs

Volumn 23, Issue 6, 2012, Pages 606-613

  Jiang, Zhongyong ^a   Chai, Jin ^b   Chuang, Henry Hon Fung ^d   Li, Shifeng ^c   Wang, Tianran ^a   Cheng, Yi ^a   Chen, Wensheng ^b   Zhou, Deshan ^c  

^a CHENGDU MILITARY GENERAL HOSPITAL   (China)

^b THIRD MILITARY MEDICAL UNIVERSITY   (China)

^c CAPITAL MEDICAL UNIVERSITY   (China)

^d HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Hong Kong)

Author keywords

A431 cells; apoptosis; artesunate; cell cycle; skin carcinoma

Indexed keywords

ARTESUNATE; BROXURIDINE; CYCLIN A1; CYCLIN B; CYCLIN D1; CYCLIN DEPENDENT KINASE 2; CYCLIN DEPENDENT KINASE 4; CYCLIN DEPENDENT KINASE 6; LIPOCORTIN 5; PROPIDIUM IODIDE; PROTEIN P21; PROTEIN P27;

APOPTOSIS; ARTICLE; CANCER CELL; CANCER INHIBITION; CELL CYCLE ARREST; CONTROLLED STUDY; DNA SYNTHESIS; DOWN REGULATION; HUMAN; HUMAN CELL; IRON DEFICIENCY; IRON OVERLOAD; KERATINOCYTE; MITOCHONDRION; PRIORITY JOURNAL; SQUAMOUS CELL CARCINOMA; STAINING; UPREGULATION; WESTERN BLOTTING;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; ARTEMISININS; CARCINOMA, SQUAMOUS CELL; CASPASE 3; CELL CYCLE CHECKPOINTS; CELL CYCLE PROTEINS; CELL LINE, TUMOR; CELL PROLIFERATION; G0 PHASE; G1 PHASE CELL CYCLE CHECKPOINTS; HUMANS; IRON; KERATINOCYTES; MITOCHONDRIA;

EID: 84862780354     PISSN: 09594973     EISSN: 14735741     Source Type: Journal    
DOI: 10.1097/CAD.0b013e328350e8ac     Document Type: Article

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