-
1
-
-
0037021402
-
Antimalarial chemotherapeutic peroxides: Artemisinin, yingzhaosu a and related compounds
-
Borstnik K., Paik I., Shapiro T.A., Posner G.H. Antimalarial chemotherapeutic peroxides: artemisinin, yingzhaosu A and related compounds. Int. J. Parasitol. 32:2002;1661-1667
-
(2002)
Int. J. Parasitol.
, vol.32
, pp. 1661-1667
-
-
Borstnik, K.1
Paik, I.2
Shapiro, T.A.3
Posner, G.H.4
-
2
-
-
0028072380
-
In vitro test on Philippine isolates of Plasmodium falciparum against four standard antimalarials and four qingahaosu derivatives
-
Bustos M.D., Gay F., Diquet B. In vitro test on Philippine isolates of Plasmodium falciparum against four standard antimalarials and four qingahaosu derivatives. Bull. World Health Organ. 72:1994;729-735
-
(1994)
Bull. World Health Organ.
, vol.72
, pp. 729-735
-
-
Bustos, M.D.1
Gay, F.2
Diquet, B.3
-
3
-
-
0037435053
-
Orally active, antimalarial, anticancer, artemisinin-derived trioxane dimers with high stability and efficacy
-
Posner G.H., Paik I.H., Sur S., McRiner A.J., Bortnik K., Xie S., et al. Orally active, antimalarial, anticancer, artemisinin-derived trioxane dimers with high stability and efficacy. J. Med. Chem. 46:2003;1060-1065
-
(2003)
J. Med. Chem.
, vol.46
, pp. 1060-1065
-
-
Posner, G.H.1
Paik, I.H.2
Sur, S.3
McRiner, A.J.4
Bortnik, K.5
Xie, S.6
-
4
-
-
0027267309
-
Cytotoxicity of artemisinin-related endoperoxides to Ehrlich ascites tumor cells
-
Woerdenbag H.J., Moskal T.A., Pras N., Malingre T.M., el-Feraly F.S., Kampinga H.H., et al. Cytotoxicity of artemisinin-related endoperoxides to Ehrlich ascites tumor cells. J. Nat. Prod. 56:1993;849-856
-
(1993)
J. Nat. Prod.
, vol.56
, pp. 849-856
-
-
Woerdenbag, H.J.1
Moskal, T.A.2
Pras, N.3
Malingre, T.M.4
El-Feraly, F.S.5
Kampinga, H.H.6
-
5
-
-
0029986996
-
Detection of apoptosis in KG-la leukemic cells treated with investigational drugs
-
Efferth T., Riicker G., Falkenberg M., Manns D., Olbrich A., Fabry U., et al. Detection of apoptosis in KG-la leukemic cells treated with investigational drugs. Arzneimittelforschung. 46:1996;196-200
-
(1996)
Arzneimittelforschung
, vol.46
, pp. 196-200
-
-
Efferth, T.1
Riicker, G.2
Falkenberg, M.3
Manns, D.4
Olbrich, A.5
Fabry, U.6
-
6
-
-
0035315838
-
The antimalarial artesunate is also active against cancer
-
Efferth T., Dustan H., Sauerbrey A., Miyachi H., Chitambar C.R. The antimalarial artesunate is also active against cancer. Int. J. Oncol. 18:2001;767-773
-
(2001)
Int. J. Oncol.
, vol.18
, pp. 767-773
-
-
Efferth, T.1
Dustan, H.2
Sauerbrey, A.3
Miyachi, H.4
Chitambar, C.R.5
-
7
-
-
0042844638
-
Molecular modes of action of artesunate in tumor cell lines
-
Efferth T., Sauerbrey A., Olbrich A., Gebhart E., Rauch P., Weber H.O., et al. Molecular modes of action of artesunate in tumor cell lines. Mol. Pharmacol. 64:2003;382-394
-
(2003)
Mol. Pharmacol.
, vol.64
, pp. 382-394
-
-
Efferth, T.1
Sauerbrey, A.2
Olbrich, A.3
Gebhart, E.4
Rauch, P.5
Weber, H.O.6
-
8
-
-
0036238927
-
Antiviral activity of artesunate towards wild-type, recombinant and ganciclovir-resistant human cytomegaloviruses
-
Efferth T., Marschall M., Wang X., Huong S.-M., Hauber I., Olbrich A., et al. Antiviral activity of artesunate towards wild-type, recombinant and ganciclovir-resistant human cytomegaloviruses. J. Mol. Med. 80:2002;223-224
-
(2002)
J. Mol. Med.
, vol.80
, pp. 223-224
-
-
Efferth, T.1
Marschall, M.2
Wang, X.3
Huong, S.-M.4
Hauber, I.5
Olbrich, A.6
-
9
-
-
0034813570
-
Artemisinin and its derivatives: An important new class of antimalarial agents
-
Balint G.A. Artemisinin and its derivatives: an important new class of antimalarial agents. Pharmacol. Ther. 90:2001;261-265
-
(2001)
Pharmacol. Ther.
, vol.90
, pp. 261-265
-
-
Balint, G.A.1
-
10
-
-
0006899513
-
Safety of artemisinin and its derivatives. A review of published and unpublished clinical trials
-
Ribeiro I.R., Olliaro P. Safety of artemisinin and its derivatives. A review of published and unpublished clinical trials. Med. Trop. (Mars). 58:1998;50-53
-
(1998)
Med. Trop. (Mars)
, vol.58
, pp. 50-53
-
-
Ribeiro, I.R.1
Olliaro, P.2
-
11
-
-
0027197112
-
Iron-dependent free radical generation from the antimalarial agent artemisinin (qinghaosu)
-
Meshnick S.R., Yang Y.Z., Lima V., Kuypers F., Kamchonwongpaisan S., Yuthavong Y. Iron-dependent free radical generation from the antimalarial agent artemisinin (qinghaosu). Antimicrob. Agents Chemother. 37:1993;1108-1114
-
(1993)
Antimicrob. Agents Chemother.
, vol.37
, pp. 1108-1114
-
-
Meshnick, S.R.1
Yang, Y.Z.2
Lima, V.3
Kuypers, F.4
Kamchonwongpaisan, S.5
Yuthavong, Y.6
-
12
-
-
0026746574
-
A region specifically oxygen-18 labeled 1,2,4-trioxane: A simple chemical model system to probe the mechanism(s) for the antimalarial activity of artemisinin (qinhaosu)
-
Posner G.H., Oh C.H. A region specifically oxygen-18 labeled 1, 2, 4-trioxane: a simple chemical model system to probe the mechanism(s) for the antimalarial activity of artemisinin (qinhaosu). J. Am. Chem. Soc. 114:1992;8328-8329
-
(1992)
J. Am. Chem. Soc.
, vol.114
, pp. 8328-8329
-
-
Posner, G.H.1
Oh, C.H.2
-
13
-
-
0028305219
-
Mechanism-based design, synthesis, and in vitro antimalarial testing of new 4-methylated trioxanes structurally related to artemisinin: The importance of a carbon-centered radical for antimalarial activity
-
Posner G.H., Oh C.H., Wang D., Gerena L., Milhous W.K., Meshnick S.R., et al. Mechanism-based design, synthesis, and in vitro antimalarial testing of new 4-methylated trioxanes structurally related to artemisinin: the importance of a carbon-centered radical for antimalarial activity. J. Med. Chem. 37:1994;1256-1258
-
(1994)
J. Med. Chem.
, vol.37
, pp. 1256-1258
-
-
Posner, G.H.1
Oh, C.H.2
Wang, D.3
Gerena, L.4
Milhous, W.K.5
Meshnick, S.R.6
-
14
-
-
0023622465
-
The antimalarial action on Plasmodium falciparum of qinghaosu and artesunate in combination with agents which modulate oxidant stress
-
Krungkrai S.R., Yuthavong Y. The antimalarial action on Plasmodium falciparum of qinghaosu and artesunate in combination with agents which modulate oxidant stress. Trans. R. Soc. Trop. Med. Hyg. 81:1987;710-714
-
(1987)
Trans. R. Soc. Trop. Med. Hyg.
, vol.81
, pp. 710-714
-
-
Krungkrai, S.R.1
Yuthavong, Y.2
-
15
-
-
0023726412
-
Adriamycin-induced free radical formation in the perfused rat heart: Implications for cardiotoxicity
-
Rajagopalan S., Politi P.M., Sinha B.K., Myers C.E. Adriamycin-induced free radical formation in the perfused rat heart: implications for cardiotoxicity. Cancer Res. 48:1988;4766-4769
-
(1988)
Cancer Res.
, vol.48
, pp. 4766-4769
-
-
Rajagopalan, S.1
Politi, P.M.2
Sinha, B.K.3
Myers, C.E.4
-
16
-
-
0033006172
-
A critical evaluation of the mechanisms of action proposed for the antitumor effects of the anthracycline antibiotics adriamycin and daunorubicin
-
Gewirtz D.A. A critical evaluation of the mechanisms of action proposed for the antitumor effects of the anthracycline antibiotics adriamycin and daunorubicin. Biochem. Pharmacol. 57:1999;727-741
-
(1999)
Biochem. Pharmacol.
, vol.57
, pp. 727-741
-
-
Gewirtz, D.A.1
-
17
-
-
0006946190
-
Neurotoxicity and artemisinin compounds do the observations in animals justify limitation of clinical use?
-
Dayan A.D. Neurotoxicity and artemisinin compounds do the observations in animals justify limitation of clinical use? Med. Trop. (Mars). 58(3 Suppl):1998;32-37
-
(1998)
Med. Trop. (Mars)
, vol.58
, Issue.3 SUPPL.
, pp. 32-37
-
-
Dayan, A.D.1
-
18
-
-
0034088857
-
A gene expression database for the molecular pharmacology of cancer
-
Scherf U., Ross D.T., Waltham M., Smith L.H., Lee J.K., Tanabe L., et al. A gene expression database for the molecular pharmacology of cancer. Nat. Genet. 24:2000;236-244
-
(2000)
Nat. Genet.
, vol.24
, pp. 236-244
-
-
Scherf, U.1
Ross, D.T.2
Waltham, M.3
Smith, L.H.4
Lee, J.K.5
Tanabe, L.6
-
19
-
-
84965822602
-
Feasibility of drug screening with panels of human tumor cell lines using a microculture tetrazolium assay
-
Alley M.C., Scudiero D.A., Monks A., Hursey M.L., Czerwinski M.J., Fine D.L., et al. Feasibility of drug screening with panels of human tumor cell lines using a microculture tetrazolium assay. Cancer Res. 48:1988;589-601
-
(1988)
Cancer Res.
, vol.48
, pp. 589-601
-
-
Alley, M.C.1
Scudiero, D.A.2
Monks, A.3
Hursey, M.L.4
Czerwinski, M.J.5
Fine, D.L.6
-
20
-
-
0025367455
-
Comparison of in vitro anticancer-drug-screening data generated with a tetrazolium assay versus a protein assay against a diverse panel of human tumor cell lines
-
Rubinstein L.V., Shoemaker R.H., Paull K.D., Simon R.M., Tosini S., Skehan P., et al. Comparison of in vitro anticancer-drug-screening data generated with a tetrazolium assay versus a protein assay against a diverse panel of human tumor cell lines. J. Natl. Cancer Inst. 82:1990;1113-1118
-
(1990)
J. Natl. Cancer Inst.
, vol.82
, pp. 1113-1118
-
-
Rubinstein, L.V.1
Shoemaker, R.H.2
Paull, K.D.3
Simon, R.M.4
Tosini, S.5
Skehan, P.6
-
21
-
-
0025066941
-
More powerful procedures for multiple significance testing
-
Hochberg Y., Benjamini Y. More powerful procedures for multiple significance testing. Stat. Med. 9:1990;811-818
-
(1990)
Stat. Med.
, vol.9
, pp. 811-818
-
-
Hochberg, Y.1
Benjamini, Y.2
-
22
-
-
0036580893
-
Controlling the rate of Type I error over a large set of statistical tests
-
Keselman H.J., Cribbie R., Holland B. Controlling the rate of Type I error over a large set of statistical tests. Br. J. Math. Stat. Psychol. 55:2002;27-39
-
(2002)
Br. J. Math. Stat. Psychol.
, vol.55
, pp. 27-39
-
-
Keselman, H.J.1
Cribbie, R.2
Holland, B.3
-
23
-
-
0037433040
-
Identifying differentially expressed genes using false discovery rate controlling procedures
-
Reiner A., Yekutieli D., Benjamini Y. Identifying differentially expressed genes using false discovery rate controlling procedures. Bioinformatics. 19:2003;368-375
-
(2003)
Bioinformatics
, vol.19
, pp. 368-375
-
-
Reiner, A.1
Yekutieli, D.2
Benjamini, Y.3
-
24
-
-
0030844372
-
Apoptosis and resistance to daunorubicin in human leukemic cells
-
Efferth T., Fabry U., Osieka R. Apoptosis and resistance to daunorubicin in human leukemic cells. Leukemia. 11:1997;1180-1186
-
(1997)
Leukemia
, vol.11
, pp. 1180-1186
-
-
Efferth, T.1
Fabry, U.2
Osieka, R.3
-
25
-
-
0037194348
-
Protein expression profiles indicative for drug resistance of non-small cell lung cancer
-
Volm M., Koomagi R., Mattern J., Efferth T. Protein expression profiles indicative for drug resistance of non-small cell lung cancer. Br. J. Cancer. 87:2002;251-257
-
(2002)
Br. J. Cancer
, vol.87
, pp. 251-257
-
-
Volm, M.1
Koomagi, R.2
Mattern, J.3
Efferth, T.4
-
26
-
-
0029868179
-
Selective high-performance liquid chromatographic determination of artesunate and alpha- and beta-dihydroartemisinin in patients with falciparum malaria
-
Batty K.T., Davis T.M., Thu L.T., Binh T.Q., Anh T.K., Ilett K.F. Selective high-performance liquid chromatographic determination of artesunate and alpha- and beta-dihydroartemisinin in patients with falciparum malaria. J. Chromatogr. B. Biomed. Appl. 677:1996;345-350
-
(1996)
J. Chromatogr. B. Biomed. Appl.
, vol.677
, pp. 345-350
-
-
Batty, K.T.1
Davis, T.M.2
Thu, L.T.3
Binh, T.Q.4
Anh, T.K.5
Ilett, K.F.6
-
27
-
-
0037021405
-
Artemisinin: Mechanisms of action, resistance and toxicity
-
Meshnick S.R. Artemisinin: mechanisms of action, resistance and toxicity. Int. J. Parasitol. 32:2002;1655-1660
-
(2002)
Int. J. Parasitol.
, vol.32
, pp. 1655-1660
-
-
Meshnick, S.R.1
-
28
-
-
0042888772
-
5-HT3-receptor antagonists in the control of delayed-onset emesis
-
Gridelli C. 5-HT3-receptor antagonists in the control of delayed-onset emesis. Anticancer Res. 23:2003;2773-2782
-
(2003)
Anticancer Res.
, vol.23
, pp. 2773-2782
-
-
Gridelli, C.1
-
29
-
-
0035044440
-
Molecular and cellular mechanisms of cardiotoxicity
-
Kang Y.R. Molecular and cellular mechanisms of cardiotoxicity. Environ. Health Perspect. 109(Suppl 1):2001;27-34
-
(2001)
Environ. Health Perspect.
, vol.109
, Issue.SUPPL. 1
, pp. 27-34
-
-
Kang, Y.R.1
-
30
-
-
0037277191
-
New understanding in cardiotoxicity
-
Kang Y.R. New understanding in cardiotoxicity. Curr. Opin. Drug Discov. Dev. 6:2003;110-116
-
(2003)
Curr. Opin. Drug Discov. Dev.
, vol.6
, pp. 110-116
-
-
Kang, Y.R.1
|