In vivo notch reactivation in differentiating cochlear hair cells induces sox2 and prox1 expression but does not disrupt hair cell maturation

Developmental Dynamics

Volumn 241, Issue 4, 2012, Pages 684-696

  Liu, Zhiyong ^a,b   Owen, Thomas ^a,c   Fang, Jie ^a   Srinivasan, R Sathish ^a   Zuo, Jian ^a  

^a ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^b UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

^c UNIVERSITY OF BATH   (United Kingdom)

Author keywords

Cochlea; Differentiation; Hair cells; Notch; Prox1; Sox2

Indexed keywords

DYE; IMMUNOGLOBULIN J RECOMBINATION SIGNAL SEQUENCE BINDING PROTEIN; PRESTIN; PROX1 PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR SOX2; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL LINEAGE; CELL MATURATION; CELL REGENERATION; CELL STRUCTURE; COCHLEA; CONTROLLED STUDY; DEVELOPMENTAL STAGE; EMBRYO; GENE INTERACTION; HAIR CELL; HISTOLOGY; IMMUNOFLUORESCENCE; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; WILD TYPE;

ANIMALS; CELL DIFFERENTIATION; CELL LINEAGE; HAIR CELLS, AUDITORY; HOMEODOMAIN PROTEINS; MICE; RECEPTORS, NOTCH; SIGNAL TRANSDUCTION; SOXB1 TRANSCRIPTION FACTORS; TUMOR SUPPRESSOR PROTEINS;

MUS;

EID: 84862777635     PISSN: 10588388     EISSN: 10970177     Source Type: Journal    
DOI: 10.1002/dvdy.23754     Document Type: Article

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