메뉴 건너뛰기




Volumn 61, Issue 2, 2012, Pages 133-140

GABA transporters mediate glycine release from cerebellum nerve endings: Roles of Ca2+channels, mitochondrial Na+/Ca2+ exchangers, vesicular GABA/glycine transporters and anion channels

Author keywords

Anion channels; Ca2+ signaling; GABA transporters; Glycine release; Mouse cerebellum; Na+ Ca2+ exchangers

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR BLOCKING AGENT; 4 AMINOBUTYRIC ACID B RECEPTOR BLOCKING AGENT; 4 AMINOBUTYRIC ACID CARRIER; 7 CHLORO 5 (2 CHLOROPHENYL) 1,5 DIHYDRO 4,1 BENZOTHIAZEPIN 2(3H) ONE; ANION CHANNEL; BAFILOMYCIN; CALCIUM CHANNEL; GLYCINE; GLYCINE TRANSPORTER 1; GLYCINE TRANSPORTER 2; NIFLUMIC ACID; OMEGA CONOTOXIN; SODIUM CALCIUM EXCHANGE PROTEIN; VESICULAR INHIBITORY AMINO ACID TRANSPORTER;

EID: 84862776143     PISSN: 01970186     EISSN: 18729754     Source Type: Journal    
DOI: 10.1016/j.neuint.2012.05.005     Document Type: Article
Times cited : (16)

References (64)
  • 1
    • 0026536556 scopus 로고
    • 2+-independent release of neurotransmitters
    • 2+-independent release of neurotransmitters J. Neurochem. 58 1992 395 405
    • (1992) J. Neurochem. , vol.58 , pp. 395-405
    • Adam-Vizi, V.1
  • 3
    • 19544382900 scopus 로고    scopus 로고
    • Glycine transporters: Crucial roles of pharmacological interest revealed by gene deletion
    • C. Aragón, and B. López-Corcuera Glycine transporters: crucial roles of pharmacological interest revealed by gene deletion Trends Pharmacol. Sci. 26 2005 283 286
    • (2005) Trends Pharmacol. Sci. , vol.26 , pp. 283-286
    • Aragón, C.1    López-Corcuera, B.2
  • 5
    • 0027376769 scopus 로고
    • Nonvesicular release of neurotransmitter
    • D. Attwell, B. Barbour, and M. Szatkowski Nonvesicular release of neurotransmitter Neuron 11 1993 401 407
    • (1993) Neuron , vol.11 , pp. 401-407
    • Attwell, D.1    Barbour, B.2    Szatkowski, M.3
  • 6
    • 0035206590 scopus 로고    scopus 로고
    • N[3-(4′-fluorophenyl)-3-(4′-phenylphenoxy)propyl] sarcosine (NFPS) is a selective persistent inhibitor of glycine transport
    • K.R. Aubrey, and R.J. Vandenberg N[3-(4′-fluorophenyl)-3-(4′- phenylphenoxy)propyl] sarcosine (NFPS) is a selective persistent inhibitor of glycine transport Br. J. Pharmacol. 134 2001 1429 1436
    • (2001) Br. J. Pharmacol. , vol.134 , pp. 1429-1436
    • Aubrey, K.R.1    Vandenberg, R.J.2
  • 8
    • 0032127595 scopus 로고    scopus 로고
    • Neuronal calcium signaling
    • M.J. Berridge Neuronal calcium signaling Neuron 21 1998 13 26
    • (1998) Neuron , vol.21 , pp. 13-26
    • Berridge, M.J.1
  • 9
    • 0027097784 scopus 로고
    • Structure and function of inhibitory glycine receptors
    • H. Betz Structure and function of inhibitory glycine receptors Q. Rev. Biophys. 25 1992 381 394
    • (1992) Q. Rev. Biophys. , vol.25 , pp. 381-394
    • Betz, H.1
  • 13
  • 14
    • 0025948834 scopus 로고
    • GABA: An excitatory transmitter in early postnatal life
    • E. Cherubini, J.L. Gaiarsa, and Y. Ben-Ari GABA: an excitatory transmitter in early postnatal life Trends Neurosci. 14 1991 515 519
    • (1991) Trends Neurosci. , vol.14 , pp. 515-519
    • Cherubini, E.1    Gaiarsa, J.L.2    Ben-Ari, Y.3
  • 20
    • 77952421764 scopus 로고    scopus 로고
    • Neurotransmitter transporters expressed in glial cells as regulators of synapse function
    • V. Eulenburg, and J. Gomeza Neurotransmitter transporters expressed in glial cells as regulators of synapse function Brain Res. Rev. 63 2010 103 112
    • (2010) Brain Res. Rev. , vol.63 , pp. 103-112
    • Eulenburg, V.1    Gomeza, J.2
  • 22
    • 0026572466 scopus 로고
    • Mobilization of dantrolene-sensitive intracellular calcium pools is involved in the cytotoxicity induced by quisqualate and N-methyl-d-aspartate but not by 2-amino-3-(3-hydroxy-5-methylisoxazol-4-yl)propionate and kainate in cultured cerebral cortical neurons
    • A. Frandsen, and A. Schousboe Mobilization of dantrolene-sensitive intracellular calcium pools is involved in the cytotoxicity induced by quisqualate and N-methyl-d-aspartate but not by 2-amino-3-(3-hydroxy-5- methylisoxazol-4-yl)propionate and kainate in cultured cerebral cortical neurons Proc. Natl. Acad. Sci. USA 89 1992 2590 2594
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 2590-2594
    • Frandsen, A.1    Schousboe, A.2
  • 23
    • 0242544067 scopus 로고    scopus 로고
    • Deletion of the mouse glycine transporter 2 results in a hyperekplexia phenotype and postnatal lethality
    • J. Gomeza, K. Ohno, S. Hülsmann, W. Armsen, V. Eulenburg, D.W. Richter, B. Laube, and H. Betz Deletion of the mouse glycine transporter 2 results in a hyperekplexia phenotype and postnatal lethality Neuron 40 2003 797 806
    • (2003) Neuron , vol.40 , pp. 797-806
    • Gomeza, J.1    Ohno, K.2    Hülsmann, S.3    Armsen, W.4    Eulenburg, V.5    Richter, D.W.6    Laube, B.7    Betz, H.8
  • 26
    • 84855853459 scopus 로고    scopus 로고
    • 3H]glycine release from chicken retina by the glycine transporter type-1 (GlyT-1) inhibitors NFPS and Org-24461
    • 3H]glycine release from chicken retina by the glycine transporter type-1 (GlyT-1) inhibitors NFPS and Org-24461 Exp. Eye Res. 94 2012 6 12
    • (2012) Exp. Eye Res. , vol.94 , pp. 6-12
    • Harsing, Jr.L.G.1    Albert, M.2    Matyus, P.3    Szenasi, G.4
  • 27
    • 0034972570 scopus 로고    scopus 로고
    • Pharmacological assessment of the role of the glycine transporter GlyT-1 in mediating high-affinity glycine uptake by rat cerebral cortex and cerebellum synaptosomes
    • H.J. Herdon, F.M. Godfrey, A.M. Brown, S. Coulton, J.R. Evans, and W.J. Cairns Pharmacological assessment of the role of the glycine transporter GlyT-1 in mediating high-affinity glycine uptake by rat cerebral cortex and cerebellum synaptosomes Neuropharmacology 41 2001 88 96
    • (2001) Neuropharmacology , vol.41 , pp. 88-96
    • Herdon, H.J.1    Godfrey, F.M.2    Brown, A.M.3    Coulton, S.4    Evans, J.R.5    Cairns, W.J.6
  • 31
    • 84856158805 scopus 로고    scopus 로고
    • Localization and function of GABA transporters GAT-1 and GAT-3 in the basal ganglia
    • X.T. Jin, A. Galvan, T. Wichmann, and Y. Smith Localization and function of GABA transporters GAT-1 and GAT-3 in the basal ganglia Front. Syst. Neurosci. 5 2011 art 63
    • (2011) Front. Syst. Neurosci. , vol.5 , pp. 63
    • Jin, X.T.1    Galvan, A.2    Wichmann, T.3    Smith, Y.4
  • 32
    • 0023091647 scopus 로고
    • Glycine potentiates the NMDA response in cultured mouse brain neurons
    • J.W. Johnson, and P. Ascher Glycine potentiates the NMDA response in cultured mouse brain neurons Nature 325 1987 529 531
    • (1987) Nature , vol.325 , pp. 529-531
    • Johnson, J.W.1    Ascher, P.2
  • 33
    • 0032540919 scopus 로고    scopus 로고
    • Corelease of two fast neurotransmitters at a central synapse
    • P. Jonas, J. Bischofberger, and J. Sandkühler Corelease of two fast neurotransmitters at a central synapse Science 281 1998 419 424
    • (1998) Science , vol.281 , pp. 419-424
    • Jonas, P.1    Bischofberger, J.2    Sandkühler, J.3
  • 34
    • 0023831030 scopus 로고
    • Gamma-aminobutyric acid transport in reconstituted preparations from rat brain: Coupled sodium and chloride fluxes
    • S. Keynan, and B.I. Kanner Gamma-aminobutyric acid transport in reconstituted preparations from rat brain: coupled sodium and chloride fluxes Biochemistry 27 1988 12 17
    • (1988) Biochemistry , vol.27 , pp. 12-17
    • Keynan, S.1    Kanner, B.I.2
  • 35
    • 0037112230 scopus 로고    scopus 로고
    • GABA becomes exciting
    • R. Kohling GABA becomes exciting Science 298 2002 1350 1351
    • (2002) Science , vol.298 , pp. 1350-1351
    • Kohling, R.1
  • 38
    • 0034973097 scopus 로고    scopus 로고
    • The glycinergic inhibitory synapse
    • P. Legendre The glycinergic inhibitory synapse Cell. Mol. Life Sci. 58 2001 760 793
    • (2001) Cell. Mol. Life Sci. , vol.58 , pp. 760-793
    • Legendre, P.1
  • 39
    • 0027428320 scopus 로고
    • Carrier-mediated release of neurotransmitters
    • G. Levi, and M. Raiteri Carrier-mediated release of neurotransmitters Trends Neurosci. 16 1993 415 419
    • (1993) Trends Neurosci. , vol.16 , pp. 415-419
    • Levi, G.1    Raiteri, M.2
  • 41
    • 76749145072 scopus 로고    scopus 로고
    • Neuronal and non-neuronal GABA transporters as targets for antiepileptic drugs
    • K.K. Madsen, H.S. White, and A. Schousboe Neuronal and non-neuronal GABA transporters as targets for antiepileptic drugs Pharmacol. Ther. 125 2010 394 401
    • (2010) Pharmacol. Ther. , vol.125 , pp. 394-401
    • Madsen, K.K.1    White, H.S.2    Schousboe, A.3
  • 42
    • 36849085955 scopus 로고    scopus 로고
    • Mechanisms of glutamate release from astrocytes
    • E.B. Malarkey, and V. Parpura Mechanisms of glutamate release from astrocytes Neurochem. Int. 52 2008 142 154
    • (2008) Neurochem. Int. , vol.52 , pp. 142-154
    • Malarkey, E.B.1    Parpura, V.2
  • 44
    • 77949737571 scopus 로고    scopus 로고
    • In vitro activation of GAT1 transporters expressed in spinal cord gliosomes stimulates glutamate release that is abnormally elevated in the SOD1/G93A(+) mouse model of amyotrophic lateral sclerosis
    • M. Milanese, S. Zappettini, E. Jacchetti, T. Bonifacino, C. Cervetto, C. Usai, and G. Bonanno In vitro activation of GAT1 transporters expressed in spinal cord gliosomes stimulates glutamate release that is abnormally elevated in the SOD1/G93A(+) mouse model of amyotrophic lateral sclerosis J. Neurochem. 113 2010 489 501
    • (2010) J. Neurochem. , vol.113 , pp. 489-501
    • Milanese, M.1    Zappettini, S.2    Jacchetti, E.3    Bonifacino, T.4    Cervetto, C.5    Usai, C.6    Bonanno, G.7
  • 45
    • 84155160658 scopus 로고    scopus 로고
    • The stressed synapse: The impact of stress and glucocorticoids on glutamate transmission
    • M. Popoli, Z. Yan, B.S. McEwen, and G. Sanacora The stressed synapse: the impact of stress and glucocorticoids on glutamate transmission Nat. Rev. 13 2012 22 37
    • (2012) Nat. Rev. , vol.13 , pp. 22-37
    • Popoli, M.1    Yan, Z.2    McEwen, B.S.3    Sanacora, G.4
  • 46
    • 0030658838 scopus 로고    scopus 로고
    • The glycine transporter GLYT2 is a reliable marker for glycine-immunoreactive neurons
    • I. Poyatos, J. Ponce, C. Aragón, C. Giménez, and F. Zafra The glycine transporter GLYT2 is a reliable marker for glycine-immunoreactive neurons Brain Res. Mol. Brain Res. 49 1997 63 70
    • (1997) Brain Res. Mol. Brain Res. , vol.49 , pp. 63-70
    • Poyatos, I.1    Ponce, J.2    Aragón, C.3    Giménez, C.4    Zafra, F.5
  • 47
    • 0034302965 scopus 로고    scopus 로고
    • Synaptosomes still viable after 25 years of superfusion
    • L. Raiteri, and M. Raiteri Synaptosomes still viable after 25 years of superfusion Neurochem. Res. 25 2000 1265 1274
    • (2000) Neurochem. Res. , vol.25 , pp. 1265-1274
    • Raiteri, L.1    Raiteri, M.2
  • 48
    • 0026699274 scopus 로고
    • GABA and glycine modulate each other's release through heterocarriers sited on the releasing axon terminals of rat central nervous system
    • M. Raiteri, G. Bonanno, and M. Pende GABA and glycine modulate each other's release through heterocarriers sited on the releasing axon terminals of rat central nervous system J. Neurochem. 59 1992 1481 1489
    • (1992) J. Neurochem. , vol.59 , pp. 1481-1489
    • Raiteri, M.1    Bonanno, G.2    Pende, M.3
  • 49
    • 0033961718 scopus 로고    scopus 로고
    • Entrapping of impermeant probes of different size into nonpermeabilized synaptosomes as a method to study presynaptic mechanisms
    • M. Raiteri, R. Sala, A. Fassio, O. Rossetto, and G. Bonanno Entrapping of impermeant probes of different size into nonpermeabilized synaptosomes as a method to study presynaptic mechanisms J. Neurochem. 74 2000 423 431
    • (2000) J. Neurochem. , vol.74 , pp. 423-431
    • Raiteri, M.1    Sala, R.2    Fassio, A.3    Rossetto, O.4    Bonanno, G.5
  • 50
    • 0141676728 scopus 로고    scopus 로고
    • Dynamic equilibrium of neurotransmitter transporters: Not just for reuptake anymore
    • G.B. Richerson, and Y. Wu Dynamic equilibrium of neurotransmitter transporters: not just for reuptake anymore J. Neurophysiol. 90 2003 1363 1374
    • (2003) J. Neurophysiol. , vol.90 , pp. 1363-1374
    • Richerson, G.B.1    Wu, Y.2
  • 51
    • 33644847375 scopus 로고    scopus 로고
    • 2+: Molecular determinants and functional consequences
    • 2+: molecular determinants and functional consequences Physiol. Rev. 86 2006 369 408
    • (2006) Physiol. Rev. , vol.86 , pp. 369-408
    • Rizzuto, R.1    Pozzan, T.2
  • 52
    • 0033757857 scopus 로고    scopus 로고
    • Neuronal and glial glycine transporters have different stoichiometries
    • M.J. Roux, and S. Supplisson Neuronal and glial glycine transporters have different stoichiometries Neuron 25 2000 373 383
    • (2000) Neuron , vol.25 , pp. 373-383
    • Roux, M.J.1    Supplisson, S.2
  • 53
    • 84865731367 scopus 로고    scopus 로고
    • Glutamate and GABA synthesis, release, transport and metabolism as targets for seizure control
    • doi:10.1016/j.neuint.2012.02.013 doi
    • Rowley, N.M., Madsen, K.K., Schousboe, A., White, H.S., 2012. Glutamate and GABA synthesis, release, transport and metabolism as targets for seizure control. Neurochem. Int., doi: http://dx.doi.org/10.1016/j.neuint.2012.02.013.
    • (2012) Neurochem. Int.
    • Rowley, N.M.1    Madsen, K.K.2    Schousboe, A.3    White, H.S.4
  • 54
    • 79951659203 scopus 로고    scopus 로고
    • GABA transport inhibitors and seizure protection: The past and future
    • A. Schousboe, K.K. Madsen, and H.S. White GABA transport inhibitors and seizure protection: the past and future Fut. Med. Chem. 3 2011 183 187
    • (2011) Fut. Med. Chem. , vol.3 , pp. 183-187
    • Schousboe, A.1    Madsen, K.K.2    White, H.S.3
  • 55
    • 33845451608 scopus 로고    scopus 로고
    • Heterogeneity of glycinergic and GABAergic interneurons in the granule cell layer of mouse cerebellum
    • M. Simat, F. Parpan, and J.M. Fritschy Heterogeneity of glycinergic and GABAergic interneurons in the granule cell layer of mouse cerebellum J. Comp. Neurol. 500 2007 71 83
    • (2007) J. Comp. Neurol. , vol.500 , pp. 71-83
    • Simat, M.1    Parpan, F.2    Fritschy, J.M.3
  • 56
    • 0036152759 scopus 로고    scopus 로고
    • Bi-directional transport of GABA in human embryonic kidney (HEK-293) cells stably expressing the rat GABA transporter GAT-1
    • H.H. Sitte, E.A. Singer, and P. Scholze Bi-directional transport of GABA in human embryonic kidney (HEK-293) cells stably expressing the rat GABA transporter GAT-1 Br. J. Pharmacol. 135 2002 93 102
    • (2002) Br. J. Pharmacol. , vol.135 , pp. 93-102
    • Sitte, H.H.1    Singer, E.A.2    Scholze, P.3
  • 57
    • 0029927346 scopus 로고    scopus 로고
    • Colocalization of GABA, glycine, and their receptors at synapses in the rat spinal cord
    • A.J. Todd, C. Watt, R.C. Spike, and W. Sieghart Colocalization of GABA, glycine, and their receptors at synapses in the rat spinal cord J. Neurosci. 16 1996 974 982
    • (1996) J. Neurosci. , vol.16 , pp. 974-982
    • Todd, A.J.1    Watt, C.2    Spike, R.C.3    Sieghart, W.4
  • 58
    • 34547190608 scopus 로고    scopus 로고
    • 2+-exchange of nerve and muscle cells
    • 2+-exchange of nerve and muscle cells Prog. Neurobiol. 82 2007 287 347
    • (2007) Prog. Neurobiol. , vol.82 , pp. 287-347
    • Török, T.L.1
  • 59
    • 0344759194 scopus 로고    scopus 로고
    • Separation of carrier mediated and vesicular release of GABA from rat brain slices
    • E.S. Vizi, and B. Sperlágh Separation of carrier mediated and vesicular release of GABA from rat brain slices Neurochem. Int. 34 1999 407 413
    • (1999) Neurochem. Int. , vol.34 , pp. 407-413
    • Vizi, E.S.1    Sperlágh, B.2
  • 60
    • 0029899405 scopus 로고    scopus 로고
    • + currents in rat cerebellar granule neurones of a membrane-permeable analogue of the calcium chelator BAPTA
    • + currents in rat cerebellar granule neurones of a membrane-permeable analogue of the calcium chelator BAPTA Br. J. Pharmacol. 118 1996 1772 1778
    • (1996) Br. J. Pharmacol. , vol.118 , pp. 1772-1778
    • Watkins, C.S.1    Mathie, A.2
  • 61
    • 22044432899 scopus 로고    scopus 로고
    • Block of TRPC5 channels by 2-aminoethoxydiphenyl borate: A differential, extracellular and voltage-dependent effect
    • S.Z. Xu, F. Zeng, G. Boulay, C. Grimm, C. Harteneck, and D.J. Beech Block of TRPC5 channels by 2-aminoethoxydiphenyl borate: a differential, extracellular and voltage-dependent effect Br. J. Pharmacol. 145 2005 405 414
    • (2005) Br. J. Pharmacol. , vol.145 , pp. 405-414
    • Xu, S.Z.1    Zeng, F.2    Boulay, G.3    Grimm, C.4    Harteneck, C.5    Beech, D.J.6
  • 64
    • 0029014595 scopus 로고
    • Regional distribution and developmental variation of the glycine transporters GLYT1 and GLYT2 in the rat CNS
    • F. Zafra, J. Gomeza, L. Olivares, C. Aragón, and C. Giménez Regional distribution and developmental variation of the glycine transporters GLYT1 and GLYT2 in the rat CNS Eur. J. Neurosci. 7 1995 1342 1352
    • (1995) Eur. J. Neurosci. , vol.7 , pp. 1342-1352
    • Zafra, F.1    Gomeza, J.2    Olivares, L.3    Aragón, C.4    Giménez, C.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.