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Pyrrole and Its Derivatives, Eds.: K.C. Majumdar, S.K. Chattopadhyay, Wiley-VCH, Weinheim, Chap.6-, 2011.
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Pyrrole and Its Derivatives, M. Dipakranjan, S. Brateen, K. D. Bidyut, Heterocycles in Natural Product Synthesis (Eds.: K.C. Majumdar, S.K. Chattopadhyay, Wiley-VCH, Weinheim, Chap.6, pp.187-220, 2011.
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Dipakranjan, M.1
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6
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84862728751
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Most of these methods allow the synthesis of 2,3,4 substitution: see, for example
-
Most of these methods allow the synthesis of 2, 3, 4 substitution: see, for example
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77955863073
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For a "one pot" synthesis 2-carboxy-5-substituted pyrroles, see e.g.
-
For a "one pot" synthesis 2-carboxy-5-substituted pyrroles, see e.g.: R. Robles-Machín, A. López-Pérez, M. González-Esguevillas, J. Adrio, J. C. Carretero, Chem. Eur. J. 2010, 16, 9864.
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11
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79960178492
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For synthesis of 2.4-pyrroles under Rh catalysis and 70°C, see
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For synthesis of 2.4-pyrroles under Rh catalysis and 70°C, see: B. Chattopadhyay, V. Gevorgyan, Org. Lett. 2011, 13, 3746.
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Chattopadhyay, B.1
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12
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84862728747
-
-
There are few reported methods for the synthesis of 2,4-pyrroles, in addition, they used expensive or toxic metals. With lanthanides, see:
-
There are few reported methods for the synthesis of 2, 4-pyrroles, in addition, they used expensive or toxic metals. With lanthanides, see:
-
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13
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0033521103
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H. Shiraishi, T. Nishitani, T. Nishihara, S. Sakaguchi, Y. Ishii, Tetrahedron 1999, 55, 13957;
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Ishii, Y.5
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14
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0030900506
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With tin, it was obtained mixture of regioisomers, see
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With tin, it was obtained mixture of regioisomers, see: M. Yasuda, J. Morimoto, I. Shibata, A. Baba, Tetrahedron Lett. 1997, 38, 3265;
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Baba, A.4
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15
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0000530604
-
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3(DME) provided limited scope and poor yield: see
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3(DME) provided limited scope and poor yield: see: E. J. Roskamp, P. S. Dragovich, J. B. Hartung Jr., S. F. Pedersen, J. Org. Chem. 1989, 54, 4736.
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19
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84862749318
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See for example
-
See for example
-
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20
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13344282738
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A. Tafi, T. Anastassopoulou, M. Botta, F. Corelli, S. Massa, M. Artico, R. Costi, R. DiSanto, R. Ragno, J. Med. Chem. 1996, 39, 1227;
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M. Botta, F. Corelli, F. Manetti, C. Mugnaini, A. Tafi, Pure Appl. Chem. 2001, 73, 1477;
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A. Tafi, R. Costi, M. Botta, R. DiSanto, F. Corelli, S. Massa, A. Ciacci, F. Manetti, M. Artico, J. Med. Chem. 2002, 45, 2720;
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23
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R. DiSanto, A. Tafi, R. Costi, M. Botta, M. Artico, F. Corelli, M. Forte, F. Caporuscio, L. Angiolella, A. T. Palamara, J. Med. Chem. 2005, 48, 5140.
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25
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84862728745
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For selected reviews on organocatalysis, see:
-
For selected reviews on organocatalysis, see:
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26
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6044269452
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P. I. Dalko, L. Moisan, Angew. Chem. 2004, 116, 5248; Angew. Chem. Int. Ed. 2004, 43, 5138;
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32
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84862747712
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For recent examples, see for example
-
For recent examples, see for example
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33
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79955905485
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For a detailed mechanism in the addition of aldehydes to nitroalkenes, see
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For a detailed mechanism in the addition of aldehydes to nitroalkenes, see: K. Patora-Komisarskaa, M. Benohouda, H. Ishikawaa, D. Seebach, Y. Hayashi, Helv. Chim. Acta 2011, 94, 719.
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47
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84862728748
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In the final crude mixture it was obtained different non-identified byproducts which justified the lower isolated yield of compound 5a.
-
In the final crude mixture it was obtained different non-identified byproducts which justified the lower isolated yield of compound 5a.
-
-
-
-
48
-
-
84862749317
-
-
Deprotection of a pyrrole with the tert-butyl group can be achieved by using acid medium, see reference5a.
-
Deprotection of a pyrrole with the tert-butyl group can be achieved by using acid medium, see reference5a.
-
-
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49
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84862752062
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For the deprotection of allyl-pyrroles, see: K. Ogasawara, T. Taniguchi, PCT Int. Appl., 9924381, 1999.
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For the deprotection of allyl-pyrroles, see: K. Ogasawara, T. Taniguchi, PCT Int. Appl., 9924381, 1999.
-
-
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50
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84862747710
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For a general review, see:
-
For a general review, see:
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51
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See following reference and references cited in there
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See following reference and references cited in there: P. D′Arrigo, D. Arosio, L. Cerioli, D. Moscatelli, S. Servi, F. Viani, D. Tessaro, Tetrahedron: Asymmetry 2011, 22, 851.
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54
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0005888816
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This mechanism was described before, see
-
This mechanism was described before, see: F. Benedetti, F. Berti, P. Nitti, G. Pitacco, E. Valentin, Gazz. Chim. Ital. 1990, 120, 25.
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55
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84862747711
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For a definition and classification of a one-pot reaction, see:
-
For a definition and classification of a one-pot reaction, see:
-
-
-
|