Antifungal agents. 11. N-substituted derivatives of 1-[(aryl)(4-aryl-1H- pyrrol-3-yl)methyl]-1H-imidazole: Synthesis, anti-Candida activity, and QSAR studies

Journal of Medicinal Chemistry

Volumn 48, Issue 16, 2005, Pages 5140-5153

  Di Santo, Roberto ^a   Tafi, Andrea ^b   Costi, Roberta ^a   Botta, Maurizo ^b   Artico, Marino ^a   Corelli, Federico ^b   Forte, Michela ^a   Caporuscio, Fabiana ^a   Angiolella, Letizia ^a   Palamara, Anna Teresa ^a  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

^b UNIVERSITY OF SIENA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

1 [(1H PYRROL 3YL)METHYL] 1H IMIDAZOLE DERIVATIVE; 1 [[4 (4 CHLOROPHENYL) 1 PROPYL 1H PYRROL 3 YL]PHENYLMETHYL] 1H IMIDAZOLE; ANTIFUNGAL AGENT; BIFONAZOLE; COORDINATION COMPOUND; DEMETHYLASE; ENZYME; FLUCONAZOLE; ITRACONAZOLE; MICONAZOLE; PYRROLE DERIVATIVE; UNCLASSIFIED DRUG;

ANTIFUNGAL ACTIVITY; ARTICLE; CANDIDA; CANDIDA ALBICANS; CHEMICAL BOND; CONTROLLED STUDY; DRUG CLASSIFICATION; DRUG DESIGN; DRUG POTENCY; DRUG SYNTHESIS; FUNGAL STRAIN; IC 50; NONHUMAN; PHARMACOPHORE; QUANTITATIVE STRUCTURE ACTIVITY RELATION; STANDARD;

ANTIFUNGAL AGENTS; CANDIDA ALBICANS; IMIDAZOLES; MICROBIAL SENSITIVITY TESTS; MODELS, MOLECULAR; PYRROLES; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 23444446586     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm048997u     Document Type: Article

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