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Volumn 9, Issue 7, 2012, Pages 805-822

Micelle-like nanoassemblies based on polymer-drug conjugates as an emerging platform for drug delivery

Author keywords

amphiphilic polymer drug conjugates; drug delivery; micelle like nanoassemblies; micelles; targeting mechanisms

Indexed keywords

ALBUMIN; CARBOXYL GROUP; CERTOLIZUMAB PEGOL; COUMARIN; DOCETAXEL; DOXORUBICIN; DRUG CARRIER; FOLATE BINDING PROTEIN; HEPARIN; HERMES ANTIGEN; HYALURONIC ACID; HYDROXYL GROUP; MACROGOL; MICELLE LIKE NANOASSEMBLY; NANOMATERIAL; PACLITAXEL; PACLITAXEL POLIGLUMEX; PEGADEMASE; PEGVISOMANT; POLOXAMER; POLYCAPROLACTONE; POLYGLUTAMIC ACID; POLYLACTIDE; POLYMER; RECOMBINANT GRANULOCYTE COLONY STIMULATING FACTOR; UNCLASSIFIED DRUG; ZINOSTATIN;

EID: 84862728843     PISSN: 17425247     EISSN: 17447593     Source Type: Journal    
DOI: 10.1517/17425247.2012.689284     Document Type: Review
Times cited : (43)

References (116)
  • 1
    • 14644439267 scopus 로고    scopus 로고
    • Cancer nanotechnology: Opportunities and challenges
    • DOI 10.1038/nrc1566
    • Ferrari M. Cancer nanotechnology: opportunities and challenges. Nat Rev Cancer 2005;5(3):161-71 (Pubitemid 40314948)
    • (2005) Nature Reviews Cancer , vol.5 , Issue.3 , pp. 161-171
    • Ferrari, M.1
  • 2
    • 77953525110 scopus 로고    scopus 로고
    • Nanotechnology and nanomedicine: Going small means aiming big
    • Teli MK, Mutalik S, Rajanikant GK. Nanotechnology and nanomedicine: going small means aiming big. Curr Pharm Des 2010;16(16):1882-92
    • (2010) Curr Pharm Des , vol.16 , Issue.16 , pp. 1882-1892
    • Teli, M.K.1    Mutalik, S.2    Rajanikant, G.K.3
  • 3
    • 77957995667 scopus 로고    scopus 로고
    • From nanotechnology to nanomedicine: Applications to cancer research
    • Seigneuric R, Markey L, Nuyten DS, et al. From nanotechnology to nanomedicine: applications to cancer research. Curr Mol Med 2010;10(7):640-52
    • (2010) Curr Mol Med , vol.10 , Issue.7 , pp. 640-652
    • Seigneuric, R.1    Markey, L.2    Nuyten, D.S.3
  • 4
    • 52949140576 scopus 로고    scopus 로고
    • Nanotechnology for nanomedicine and delivery of drugs
    • Venugopal J, Prabhakaran MP, Low S, et al. Nanotechnology for nanomedicine and delivery of drugs. Curr Pharm Des 2008;14(22):2184-200
    • (2008) Curr Pharm Des , vol.14 , Issue.22 , pp. 2184-2200
    • Venugopal, J.1    Prabhakaran, M.P.2    Low, S.3
  • 5
    • 29544448116 scopus 로고    scopus 로고
    • Polymer conjugates: Nanosized medicines for treating cancer
    • DOI 10.1016/j.tibtech.2005.11.006, PII S0167779905003021
    • Vicent MJ, Duncan R. Polymer conjugates: nanosized medicines for treating cancer. Trends Biotechnol 2006;24(1):39-47 (Pubitemid 43017749)
    • (2006) Trends in Biotechnology , vol.24 , Issue.1 , pp. 39-47
    • Vicent, M.J.1    Duncan, R.2
  • 6
    • 33745703563 scopus 로고    scopus 로고
    • Polymer therapeutics: Concepts and applications
    • DOI 10.1002/anie.200502113
    • Haag R, Kratz F. Polymer therapeutics: concepts and applications. Angew Chem Int Ed Engl 2006;45(8):1198-215 A review on the current status of polymer therapeutics. (Pubitemid 44097641)
    • (2006) Angewandte Chemie - International Edition , vol.45 , Issue.8 , pp. 1198-1215
    • Haag, R.1    Kratz, F.2
  • 7
    • 0016622773 scopus 로고
    • Structure and properties of pharmacologically active polymers
    • Landmark publication introducing the concept of polymeric prodrug
    • Ringsdorf H. Structure and properties of pharmacologically active polymers. J Polym Sci Polym Symp 1975;51:135-53 Landmark publication introducing the concept of polymeric prodrug.
    • (1975) J Polym Sci Polym Symp , vol.51 , pp. 135-153
    • Ringsdorf, H.1
  • 8
    • 0018801628 scopus 로고
    • Some properties of polyethylene glycol: Phenylalanine ammonia-lyase adducts
    • Wieder KJ, Palczuk NC, van Es T, Davis FF. Some properties of polyethylene glycol: phenylalanine ammonia-lyase adducts. J Biol Chem 1979;254(24):12579-87
    • (1979) J Biol Chem , vol.254 , Issue.24 , pp. 12579-12587
    • Wieder, K.J.1    Palczuk, N.C.2    Van Es, T.3    Davis, F.F.4
  • 9
    • 0037124546 scopus 로고    scopus 로고
    • The origin of pegnology
    • DOI 10.1016/S0169-409X(02)00021-2, PII S0169409X02000212
    • Davis FF. The origin of pegnology. Adv Drug Deliv Rev 2002;54(4):457-8 Commentary on protein PEGylation. (Pubitemid 34615542)
    • (2002) Advanced Drug Delivery Reviews , vol.54 , Issue.4 , pp. 457-458
    • Davis, F.F.1
  • 12
    • 0346551010 scopus 로고
    • Polymer conjugates with anticancer activity
    • Putnam D, Kopecek J. Polymer conjugates with anticancer activity. Adv Polym Sci 1995;122:55-123
    • (1995) Adv Polym Sci , vol.122 , pp. 55-123
    • Putnam, D.1    Kopecek, J.2
  • 13
    • 0002405110 scopus 로고
    • Soluble synthetic polymers as potential drug carriers
    • Duncan R, Kopecek J. Soluble synthetic polymers as potential drug carriers. Adv Polym Sci 1984;57:51-101
    • (1984) Adv Polym Sci , vol.57 , pp. 51-101
    • Duncan, R.1    Kopecek, J.2
  • 14
    • 0026757191 scopus 로고
    • Drug-polymer conjugates: Potential for improved chemotherapy
    • Duncan R. Drug-polymer conjugates: potential for improved chemotherapy. Anticancer Drugs 1992;3(3):175-210
    • (1992) Anticancer Drugs , vol.3 , Issue.3 , pp. 175-210
    • Duncan, R.1
  • 15
    • 0038387390 scopus 로고    scopus 로고
    • The dawning era of polymer therapeutics
    • DOI 10.1038/nrd1088
    • Duncan R. The dawning era of polymer therapeutics. Nat Rev Drug Discov 2003;2(5):347-60 (Pubitemid 37361705)
    • (2003) Nature Reviews Drug Discovery , vol.2 , Issue.5 , pp. 347-360
    • Duncan, R.1
  • 16
    • 0041664881 scopus 로고    scopus 로고
    • Polymer-protein and polymer-drug conjugates in cancer therapy
    • Thanou M, Duncan R. Polymer--protein and polymer--drug conjugates in cancer therapy. Curr Opin Investig Drugs 2003;4(6):701-9 (Pubitemid 36916711)
    • (2003) Current Opinion in Investigational Drugs , vol.4 , Issue.6 , pp. 701-709
    • Thanou, M.1    Duncan, R.2
  • 17
    • 45849137147 scopus 로고    scopus 로고
    • Polymer conjugates as therapeutics: Future trends, challenges and opportunities
    • DOI 10.1517/17425247.5.5.593
    • Vicent MJ, Dieudonne L, Carbajo RJ, Pineda-Lucena A. Polymer conjugates as therapeutics: future trends, challenges and opportunities. Expert Opin Drug Deliv 2008;5(5):593-614 (Pubitemid 351888105)
    • (2008) Expert Opinion on Drug Delivery , vol.5 , Issue.5 , pp. 593-614
    • Vicent, M.J.1    Dieudonne, L.2    Carbajo, R.J.3    Pineda-Lucena, A.4
  • 18
    • 38449087619 scopus 로고    scopus 로고
    • Polymer-drug conjugates: Current status and future trends
    • DOI 10.2741/2882
    • Greco F, Vicent MJ. Polymer--drug conjugates: current status and future trends. Front Biosci 2008;13:2744-56 (Pubitemid 351611606)
    • (2008) Frontiers in Bioscience , vol.13 , Issue.7 , pp. 2744-2756
    • Greco, F.1    Vicent, M.J.2
  • 19
    • 0001079515 scopus 로고
    • Solution properties of drug carriers based on poly[N-(2-hydroxypropyl) methacrylamide] containing biodegradable bonds
    • First polymer assembly drug carrier based on HPMA-drug conjugates
    • Ulbrich K, Konak C, Tuzar Z, Kopecek J. Solution properties of drug carriers based on poly[N-(2-hydroxypropyl)methacrylamide] containing biodegradable bonds. Makromol Chem 1987;188(6):1261-72 First polymer assembly drug carrier based on HPMA-drug conjugates.
    • (1987) Makromol Chem , vol.188 , Issue.6 , pp. 1261-1272
    • Ulbrich, K.1    Konak, C.2    Tuzar, Z.3    Kopecek, J.4
  • 20
    • 78651279520 scopus 로고    scopus 로고
    • Polymeric micelles in anticancer therapy: Targeting, imaging and triggered release
    • Oerlemans C, Bult W, Bos M, et al. Polymeric micelles in anticancer therapy: targeting, imaging and triggered release. Pharm Res 2010;27(12):2569-89
    • (2010) Pharm Res , vol.27 , Issue.12 , pp. 2569-2589
    • Oerlemans, C.1    Bult, W.2    Bos, M.3
  • 21
    • 26944452043 scopus 로고    scopus 로고
    • PEGylation, successful approach to drug delivery
    • DOI 10.1016/S1359-6446(05)03575-0, PII S1359644605035750
    • Veronese FM, Pasut G. PEGylation, successful approach to drug delivery. Drug Discov Today 2005;10(21):1451-8 (Pubitemid 41483874)
    • (2005) Drug Discovery Today , vol.10 , Issue.21 , pp. 1451-1458
    • Veronese, F.M.1    Pasut, G.2
  • 22
    • 70349988803 scopus 로고    scopus 로고
    • PEG conjugates in clinical development or use as anticancer agents: An overview
    • Review describing PEG conjugates of proteins or low molecular weight drugs in clinical development
    • Pasut G, Veronese FM. PEG conjugates in clinical development or use as anticancer agents: an overview. Adv Drug Deliv Rev 2009;61(13):1177-88 Review describing PEG conjugates of proteins or low molecular weight drugs in clinical development.
    • (2009) Adv Drug Deliv Rev , vol.61 , Issue.13 , pp. 1177-1188
    • Pasut, G.1    Veronese, F.M.2
  • 23
    • 35348906219 scopus 로고    scopus 로고
    • MMPs-specific PEGylated peptide-DOX conjugate micelles that can contain free doxorubicin
    • DOI 10.1016/j.ejpb.2007.03.023, PII S0939641107001142
    • Lee GY, Park K, Kim SY, Byun Y. MMPs-specific PEGylated peptide-DOX conjugate micelles that can contain free doxorubicin. Eur J Pharm Biopharm 2007;67(3):646-54 (Pubitemid 47576605)
    • (2007) European Journal of Pharmaceutics and Biopharmaceutics , vol.67 , Issue.3 , pp. 646-654
    • Lee, G.Y.1    Park, K.2    Kim, S.Y.3    Byun, Y.4
  • 24
    • 79951884831 scopus 로고    scopus 로고
    • Multifunctional synthetic poly(L-glutamic acid)-based cancer therapeutic and imaging agents
    • Melancon MP, Li C. Multifunctional synthetic poly(L-glutamic acid)-based cancer therapeutic and imaging agents. Mol imaging 2011;10(1):28-42
    • (2011) Mol Imaging , vol.10 , Issue.1 , pp. 28-42
    • Melancon, M.P.1    Li, C.2
  • 25
    • 0035816202 scopus 로고    scopus 로고
    • Water-soluble poly-(L-glutamic acid)-Gly-camptothecin conjugates enhance camptothecin stability and efficacy in vivo
    • DOI 10.1016/S0168-3659(01)00323-6, PII S0168365901003236
    • Singer JW, Bhatt R, Tulinsky J, et al. Water-soluble poly-(L-glutamic acid)-Gly-camptothecin conjugates enhance camptothecin stability and efficacy in vivo. J Control Release 2001;74(1-3):243-7 (Pubitemid 32727627)
    • (2001) Journal of Controlled Release , vol.74 , Issue.1-3 , pp. 243-247
    • Singer, J.W.1    Bhatt, R.2    Tulinsky, J.3    Buhler, K.R.4    Heasley, E.5    Klein, P.6    De Vries, P.7
  • 26
    • 12744269417 scopus 로고    scopus 로고
    • CT-2103: A novel macromolecular taxane with potential advantages compared with conventional taxanes
    • Langer CJ. CT-2103: a novel macromolecular taxane with potential advantages compared with conventional taxanes. Clin Lung Cancer 2004;6(Suppl 2):S85-8
    • (2004) Clin Lung Cancer , vol.6 , Issue.SUPPL. 2
    • Langer, C.J.1
  • 27
    • 34247629652 scopus 로고    scopus 로고
    • Paclitaxel poliglumex (PPX, CT-2103): Macromolecular medicine for advanced non-small-cell lung cancer
    • DOI 10.1586/14737140.7.4.415
    • Bonomi P. Paclitaxel poliglumex (PPX, CT-2103): macromolecular medicine for advanced non-small-cell lung cancer. Expert Rev Anticancer Ther 2007;7(4):415-22 (Pubitemid 46681797)
    • (2007) Expert Review of Anticancer Therapy , vol.7 , Issue.4 , pp. 415-422
    • Bonomi, P.1
  • 28
    • 33745886796 scopus 로고    scopus 로고
    • Pioneer: A phase III randomized trial of paclitaxel poliglumex versus paclitaxel in chemotherapy-naive women with advanced-stage non-small-cell lung cancer and performance status of 2
    • Albain KS, Belani CP, Bonomi P, et al. Pioneer: a phase III randomized trial of paclitaxel poliglumex versus paclitaxel in chemotherapy-naive women with advanced-stage non-small-cell lung cancer and performance status of 2. Clin Lung Cancer 2006;7(6):417-19 (Pubitemid 44043553)
    • (2006) Clinical Lung Cancer , vol.7 , Issue.6 , pp. 417-419
    • Albain, K.S.1    Belani, C.P.2    Bonomi, P.3    O'Byrne, K.J.4    Schiller, J.H.5    Socinski, M.6
  • 30
    • 42749091133 scopus 로고    scopus 로고
    • Polymer-drug conjugates: Recent development in clinical oncology
    • Li C, Wallace S. Polymer-drug conjugates: recent development in clinical oncology. Adv Drug Deliv Rev 2008;60(8):886-98
    • (2008) Adv Drug Deliv Rev , vol.60 , Issue.8 , pp. 886-898
    • Li, C.1    Wallace, S.2
  • 31
    • 33745819580 scopus 로고    scopus 로고
    • Preparation and characterization of folic acid linked poly(L-glutamate) nanoparticles for cancer targeting
    • Lee YK. Preparation and characterization of folic acid linked poly(L-glutamate) nanoparticles for cancer targeting. Macromol Res 2006;14(3):387-93
    • (2006) Macromol Res , vol.14 , Issue.3 , pp. 387-393
    • Lee, Y.K.1
  • 32
    • 77649190943 scopus 로고    scopus 로고
    • Preclinical efficacy studies of a novel nanoparticle-based formulation of paclitaxel that out-performs Abraxane
    • Feng ZL, Zhao G, Yu L, et al. Preclinical efficacy studies of a novel nanoparticle-based formulation of paclitaxel that out-performs Abraxane. Cancer Chemother Pharmacol 2010;65(5):923-30
    • (2010) Cancer Chemother Pharmacol , vol.65 , Issue.5 , pp. 923-930
    • Feng, Z.L.1    Zhao, G.2    Yu, L.3
  • 33
    • 75549085440 scopus 로고    scopus 로고
    • Pharmacokinetics and tissue distribution of PGG-paclitaxel, a novel macromolecular formulation of paclitaxel, in nu/nu mice bearing NCI-460 lung cancer xenografts
    • Wang XH, Zhao G, Van S, et al. Pharmacokinetics and tissue distribution of PGG-paclitaxel, a novel macromolecular formulation of paclitaxel, in nu/nu mice bearing NCI-460 lung cancer xenografts. Cancer Chemother Pharmacol 2010;65(3):515-26
    • (2010) Cancer Chemother Pharmacol , vol.65 , Issue.3 , pp. 515-526
    • Wang, X.H.1    Zhao, G.2    Van, S.3
  • 34
    • 84858260797 scopus 로고    scopus 로고
    • Physicochemical properties and biocompatibility of a polymer-paclitaxel conjugate for cancer treatment
    • Yang DB, Van S, Liu J, et al. Physicochemical properties and biocompatibility of a polymer-paclitaxel conjugate for cancer treatment. Int J Nanomed 2011;6:2557-66
    • (2011) Int J Nanomed , vol.6 , pp. 2557-2566
    • Yang, D.B.1    Van, S.2    Liu, J.3
  • 35
    • 79251519910 scopus 로고    scopus 로고
    • Synthesis, characterization, and biological evaluation of poly(Lgamma-glutamyl-glutamine)-paclitaxel nanoconjugate
    • Van S, Das SK, Wang XH, et al. Synthesis, characterization, and biological evaluation of poly(Lgamma-glutamyl-glutamine)-paclitaxel nanoconjugate. Int J Nanomed 2010;5:825-37
    • (2010) Int J Nanomed , vol.5 , pp. 825-837
    • Van, S.1    Das, S.K.2    Wang, X.H.3
  • 36
    • 18844423259 scopus 로고    scopus 로고
    • Hyaluronic acid: A unique topical vehicle for the localized delivery of drugs to the skin
    • DOI 10.1111/j.1468-3083.2004.01180.x
    • Brown MB, Jones SA. Hyaluronic acid: a unique topical vehicle for the localized delivery of drugs to the skin. J Eur Acad Dermatol Venereol 2005;19(3):308-18 (Pubitemid 40691707)
    • (2005) Journal of the European Academy of Dermatology and Venereology , vol.19 , Issue.3 , pp. 308-318
    • Brown, M.B.1    Jones, S.A.2
  • 37
    • 70849114663 scopus 로고    scopus 로고
    • Target specific and long-acting delivery of protein, peptide, and nucleotide therapeutics using hyaluronic acid derivatives
    • Oh EJ, Park K, Kim KS, et al. Target specific and long-acting delivery of protein, peptide, and nucleotide therapeutics using hyaluronic acid derivatives. J Control Release 2010;141(1):2-12
    • (2010) J Control Release , vol.141 , Issue.1 , pp. 2-12
    • Oh, E.J.1    Park, K.2    Kim, K.S.3
  • 38
    • 79955063673 scopus 로고    scopus 로고
    • Hyaluronan-CD44 interactions as potential targets for cancer therapy
    • Misra S, Heldin P, Hascall VC, et al. Hyaluronan-CD44 interactions as potential targets for cancer therapy. FEBS J 2011;278(9):1429-43
    • (2011) FEBS J , vol.278 , Issue.9 , pp. 1429-1443
    • Misra, S.1    Heldin, P.2    Hascall, V.C.3
  • 39
    • 0027513932 scopus 로고
    • Identification of two hyaluronan-binding domains in the hyaluronan receptor RHAMM
    • Yang B, Zhang L, Turley EA. Identification of two hyaluronan-binding domains in the hyaluronan receptor RHAMM. J Biol Chem 1993;268(12):8617-23 (Pubitemid 23118644)
    • (1993) Journal of Biological Chemistry , vol.268 , Issue.12 , pp. 8617-8623
    • Yang, B.1    Zhang, L.2    Turley, E.A.3
  • 40
    • 80055068206 scopus 로고    scopus 로고
    • Role of receptor for hyaluronic acid-mediated motility (RHAMM) in low molecular weight hyaluronan (LMWHA)-mediated fibrosarcoma cell adhesion
    • Kouvidi K, Berdiaki A, Nikitovic D, et al. Role of receptor for hyaluronic acid-mediated motility (RHAMM) in low molecular weight hyaluronan (LMWHA)-mediated fibrosarcoma cell adhesion. J Biol Chem 2011;286(44):38509-20
    • (2011) J Biol Chem , vol.286 , Issue.44 , pp. 38509-38520
    • Kouvidi, K.1    Berdiaki, A.2    Nikitovic, D.3
  • 41
    • 79955831504 scopus 로고    scopus 로고
    • Hyaluronan: From biomimetic to industrial business strategy
    • Murano E, Perin D, Khan R, Bergamin M. Hyaluronan: from biomimetic to industrial business strategy. Nat Prod Commun 2011;6(4):555-72
    • (2011) Nat Prod Commun , vol.6 , Issue.4 , pp. 555-572
    • Murano, E.1    Perin, D.2    Khan, R.3    Bergamin, M.4
  • 42
    • 77952684602 scopus 로고    scopus 로고
    • Nanostructured hyaluronic acid-based materials for active delivery to cancer
    • Ossipov DA. Nanostructured hyaluronic acid-based materials for active delivery to cancer. Expert Opin Drug Deliv 2010;7(6):681-703
    • (2010) Expert Opin Drug Deliv , vol.7 , Issue.6 , pp. 681-703
    • Ossipov, D.A.1
  • 43
    • 45749088187 scopus 로고    scopus 로고
    • Hyaluronic acid-paclitaxel conjugate micelles: Synthesis, characterization, and antitumor activity
    • DOI 10.1021/bc8000485
    • Lee H, Lee K, Park TG. Hyaluronic acid-paclitaxel conjugate micelles: synthesis, characterization, and antitumor activity. Bioconjug Chem 2008;19(6):1319-25 (Pubitemid 351874956)
    • (2008) Bioconjugate Chemistry , vol.19 , Issue.6 , pp. 1319-1325
    • Lee, H.1    Lee, K.2    Tae, G.P.3
  • 44
    • 0033635310 scopus 로고    scopus 로고
    • Heparin and heparan sulfate: Biosynthesis, structure and function
    • Sasisekharan R, Venkataraman G. Heparin and heparan sulfate: biosynthesis, structure and function. Curr Opin Chem Biol 2000;4(6):626-31
    • (2000) Curr Opin Chem Biol , vol.4 , Issue.6 , pp. 626-631
    • Sasisekharan, R.1    Venkataraman, G.2
  • 45
    • 0035984272 scopus 로고    scopus 로고
    • Heparin and heparan sulfate: Structure and function
    • DOI 10.1039/b100916h
    • Rabenstein DL. Heparin and heparan sulfate: structure and function. Nat Prod Rep 2002;19(3):312-31 (Pubitemid 34656777)
    • (2002) Natural Product Reports , vol.19 , Issue.3 , pp. 312-331
    • Rabenstein, D.L.1
  • 46
    • 0015853889 scopus 로고
    • Anticoagulant action of heparin
    • Damus PS, Hicks M, Rosenberg RD. Anticoagulant action of heparin. Nature 1973;246(5432):355-7
    • (1973) Nature , vol.246 , Issue.5432 , pp. 355-357
    • Damus, P.S.1    Hicks, M.2    Rosenberg, R.D.3
  • 47
    • 77955482977 scopus 로고    scopus 로고
    • Antimetastatic activities of heparins and modified heparins. Experimental evidence
    • Borsig L. Antimetastatic activities of heparins and modified heparins. Experimental evidence. Thromb Res 2010;125(Suppl 2):S66-71
    • (2010) Thromb Res , vol.125 , Issue.SUPPL. 2
    • Borsig, L.1
  • 48
    • 77958161326 scopus 로고    scopus 로고
    • Heparin as an inhibitor of cancer progression
    • Borsig L. Heparin as an inhibitor of cancer progression. Prog Mol Biol Transl Sci 2010;93:335-49
    • (2010) Prog Mol Biol Transl Sci , vol.93 , pp. 335-349
    • Borsig, L.1
  • 49
    • 48549084196 scopus 로고    scopus 로고
    • The activities of heparan sulfate and its analogue heparin are dictated by biosynthesis, sequence, and conformation
    • Skidmore MA, Guimond SE, Rudd TR, et al. The activities of heparan sulfate and its analogue heparin are dictated by biosynthesis, sequence, and conformation. Connect Tissue Res 2008;49(3):140-4
    • (2008) Connect Tissue Res , vol.49 , Issue.3 , pp. 140-144
    • Skidmore, M.A.1    Guimond, S.E.2    Rudd, T.R.3
  • 50
    • 72449141425 scopus 로고    scopus 로고
    • Heparin-paclitaxel conjugates as drug delivery system: Synthesis, self-assembly property, drug release, and antitumor activity
    • Wang Y, Xin DC, Liu KJ, et al. Heparin-paclitaxel conjugates as drug delivery system: synthesis, self-assembly property, drug release, and antitumor activity. Bioconjug Chem 2009;20(12):2214-21
    • (2009) Bioconjug Chem , vol.20 , Issue.12 , pp. 2214-2221
    • Wang, Y.1    Xin, D.C.2    Liu, K.J.3
  • 51
    • 84855813140 scopus 로고    scopus 로고
    • Albumin-based nanoparticles as potential controlled release drug delivery systems
    • Elzoghby AO, Samy WM, Elgindy NA. Albumin-based nanoparticles as potential controlled release drug delivery systems. J Control Release 2012;157(2):168-82
    • (2012) J Control Release , vol.157 , Issue.2 , pp. 168-182
    • Elzoghby, A.O.1    Samy, W.M.2    Elgindy, N.A.3
  • 52
    • 56949084877 scopus 로고    scopus 로고
    • Albumin as a drug carrier: Design of prodrugs, drug conjugates and nanoparticles
    • Kratz F. Albumin as a drug carrier: design of prodrugs, drug conjugates and nanoparticles. J Control Release 2008;132(3):171-83
    • (2008) J Control Release , vol.132 , Issue.3 , pp. 171-183
    • Kratz, F.1
  • 53
    • 66149129222 scopus 로고    scopus 로고
    • Albumin-bound formulation of paclitaxel (Abraxane ABI-007) in the treatment of breast cancer
    • Review discribing the clinical studies of Abraxane® in the treatment of breast cancer
    • Miele E, Spinelli GP, Miele E, et al. Albumin-bound formulation of paclitaxel (Abraxane ABI-007) in the treatment of breast cancer. Int J Nanomed 2009;4:99-105 Review discribing the clinical studies of Abraxane® in the treatment of breast cancer.
    • (2009) Int J Nanomed , vol.4 , pp. 99-105
    • Miele, E.1    Spinelli, G.P.2    Miele, E.3
  • 54
    • 68249129865 scopus 로고    scopus 로고
    • Docetaxel-albumin conjugates: Preparation, in vitro evaluation and biodistribution studies
    • Esmaeili F, Dinarvand R, Ghahremani MH, et al. Docetaxel-albumin conjugates: preparation, in vitro evaluation and biodistribution studies. J Pharm Sci 2009;98(8):2718-30
    • (2009) J Pharm Sci , vol.98 , Issue.8 , pp. 2718-2730
    • Esmaeili, F.1    Dinarvand, R.2    Ghahremani, M.H.3
  • 55
    • 33747723416 scopus 로고    scopus 로고
    • Biodegradability and biodegradation of poly(lactide)
    • DOI 10.1007/s00253-006-0488-1
    • Tokiwa Y, Calabia BP. Biodegradability and biodegradation of poly(lactide). Appl Microbiol Biotechnol 2006;72(2):244-51 (Pubitemid 44273047)
    • (2006) Applied Microbiology and Biotechnology , vol.72 , Issue.2 , pp. 244-251
    • Tokiwa, Y.1    Calabia, B.P.2
  • 56
    • 3342970514 scopus 로고    scopus 로고
    • Biodegradation of poly(L-lactide)
    • DOI 10.1023/B:BILE.0000025927.31028.e3
    • Tokiwa Y, Jarerat A. Biodegradation of poly(L-lactide). Biotechnol Lett 2004;26(10):771-7 (Pubitemid 38982853)
    • (2004) Biotechnology Letters , vol.26 , Issue.10 , pp. 771-777
    • Tokiwa, Y.1    Jarerat, A.2
  • 57
    • 79955417361 scopus 로고    scopus 로고
    • From lactic acid to poly(lactic acid) (PLA): Characterization and analysis of PLA and its precursors
    • Inkinen S, Hakkarainen M, Albertsson AC, Sodergard A. From lactic acid to poly(lactic acid) (PLA): characterization and analysis of PLA and its precursors. Biomacromolecules 2011;12(3):523-32
    • (2011) Biomacromolecules , vol.12 , Issue.3 , pp. 523-532
    • Inkinen, S.1    Hakkarainen, M.2    Albertsson, A.C.3    Sodergard, A.4
  • 58
    • 9644266802 scopus 로고    scopus 로고
    • Synthesis and characterization of the paclitaxel/MPEG-PLA block copolymer conjugate
    • DOI 10.1016/j.biomaterials.2004.06.024, PII S0142961204005630
    • Zhang X, Li Y, Chen X, et al. Synthesis and characterization of the paclitaxel/ MPEG-PLA block copolymer conjugate. Biomaterials 2005;26(14):2121-8 (Pubitemid 39575355)
    • (2005) Biomaterials , vol.26 , Issue.14 , pp. 2121-2128
    • Zhang, X.1    Li, Y.2    Chen, X.3    Wang, X.4    Xu, X.5    Liang, Q.6    Hu, J.7    Jing, X.8
  • 59
    • 74749085098 scopus 로고    scopus 로고
    • Comparative study of paclitaxel physically encapsulated in and chemically conjugated with PEG-PLA
    • Xu X, Zhang X, Wang X, et al. Comparative study of paclitaxel physically encapsulated in and chemically conjugated with PEG-PLA. Polym Adv Technol 2009;20(11):843-8
    • (2009) Polym Adv Technol , vol.20 , Issue.11 , pp. 843-848
    • Xu, X.1    Zhang, X.2    Wang, X.3
  • 60
    • 84861210107 scopus 로고    scopus 로고
    • Experimental study on biodegradable polymer-paclitaxel conjugate micelles for chemotherapy of C6 glioma
    • Wang Z, Hu X, Yue J, Jing XB. Experimental study on biodegradable polymer-paclitaxel conjugate micelles for chemotherapy of C6 glioma. J Control Release 2011;152(Suppl 1):e41-2
    • (2011) J Control Release , vol.152 , Issue.SUPPL. 1
    • Wang, Z.1    Hu, X.2    Yue, J.3    Jing, X.B.4
  • 61
    • 0035966546 scopus 로고    scopus 로고
    • Biodegradable polymeric micelles composed of doxorubicin conjugated PLGA-PEG block copolymer
    • DOI 10.1016/S0168-3659(00)00340-0, PII S0168365900003400
    • Yoo HS, Park TG. Biodegradable polymeric micelles composed of doxorubicin conjugated PLGA-PEG block copolymer. J Control Release 2001;70(1-2):63-70 (Pubitemid 32144793)
    • (2001) Journal of Controlled Release , vol.70 , Issue.1-2 , pp. 63-70
    • Yoo, H.S.1    Park, T.G.2
  • 62
    • 1842638560 scopus 로고    scopus 로고
    • Folate receptor targeted biodegradable polymeric doxorubicin micelles
    • DOI 10.1016/j.jconrel.2004.02.003, PII S0168365904000811
    • Yoo HS, Park TG. Folate receptor targeted biodegradable polymeric doxorubicin micelles. J Control Release 2004;96(2):273-83 (Pubitemid 38481509)
    • (2004) Journal of Controlled Release , vol.96 , Issue.2 , pp. 273-283
    • Yoo, H.S.1    Park, T.G.2
  • 63
    • 77956541489 scopus 로고    scopus 로고
    • Improved therapeutic effect of DOX-PLGA-PEG micelles decorated with bivalent fragment HAb18 F(ab′)(2) for hepatocellular carcinoma
    • Jin C, Qian NS, Zhao W, et al. Improved therapeutic effect of DOX-PLGA-PEG micelles decorated with bivalent fragment HAb18 F(ab′)(2) for hepatocellular carcinoma. Biomacromolecules 2010;11(9):2422-31
    • (2010) Biomacromolecules , vol.11 , Issue.9 , pp. 2422-2431
    • Jin, C.1    Qian, N.S.2    Zhao, W.3
  • 64
    • 84861207054 scopus 로고    scopus 로고
    • Preparation and characterization of targeted DOX-PLGA-PEG micelles decorated with bivalent fragment HAb18 F(ab′)2 for treatment of hepatocellular carcinoma
    • Jin C, Yang WQ, Bai L, et al. Preparation and characterization of targeted DOX-PLGA-PEG micelles decorated with bivalent fragment HAb18 F(ab′)2 for treatment of hepatocellular carcinoma. J Control Release 2011;152(Suppl 1):e14-15
    • (2011) J Control Release , vol.152 , Issue.SUPPL. 1
    • Jin, C.1    Yang, W.Q.2    Bai, L.3
  • 65
    • 77952208384 scopus 로고    scopus 로고
    • Poly(ethylene glycol)-b-poly(epsilon-caprolactone) micelles containing chemically conjugated and physically entrapped docetaxel: Synthesis, characterization, and the influence of the drug on micelle morphology
    • Mikhail AS, Allen C. Poly(ethylene glycol)-b-poly(epsilon-caprolactone) micelles containing chemically conjugated and physically entrapped docetaxel: synthesis, characterization, and the influence of the drug on micelle morphology. Biomacromolecules 2010;11(5):1273-80
    • (2010) Biomacromolecules , vol.11 , Issue.5 , pp. 1273-1280
    • Mikhail, A.S.1    Allen, C.2
  • 66
    • 0020796811 scopus 로고
    • On the application of fourier transform infrared spectroscopy to the elucidation of specific interactions in miscible polyester-poly(vinyl chloride) blends
    • Varnell DF, Moskala EJ, Painter PC, Coleman MM. On the application of fourier transform infrared spectroscopy to the elucidation of specific interactions in miscible polyester-poly(vinyl chloride) blends. Polym Eng Sci 1983;23(12):658-62
    • (1983) Polym Eng Sci , vol.23 , Issue.12 , pp. 658-662
    • Varnell, D.F.1    Moskala, E.J.2    Painter, P.C.3    Coleman, M.M.4
  • 67
    • 0027492164 scopus 로고
    • Determination of protein secondary structure by Fourier transform infrared spectroscopy: A critical assessment
    • DOI 10.1021/bi00053a001
    • Surewicz WK, Mantsch HH, Chapman D. Determination of protein secondary structure by fourier transform infrared spectroscopy: a critical assessment. Biochemistry 1993;32(2):389-94 (Pubitemid 23034873)
    • (1993) Biochemistry , vol.32 , Issue.2 , pp. 389-394
    • Surewicz, W.K.1    Mantsch, H.H.2    Chapman, D.3
  • 68
    • 77953001848 scopus 로고    scopus 로고
    • Application of spectroscopic methods for structural analysis of chitin and chitosan
    • Kumirska J, Czerwicka M, Kaczynski Z, et al. Application of spectroscopic methods for structural analysis of chitin and chitosan. Mar drugs 2010;8(5):1567-636
    • (2010) Mar Drugs , vol.8 , Issue.5 , pp. 1567-1636
    • Kumirska, J.1    Czerwicka, M.2    Kaczynski, Z.3
  • 69
    • 77956011455 scopus 로고    scopus 로고
    • Nanomicelle with long-term circulation and enhanced stability of camptothecin based on mPEGylated alpha,-poly (L-aspartic acid)-camptothecin conjugate
    • Zhang WL, Huang J, Fan NQ, et al. Nanomicelle with long-term circulation and enhanced stability of camptothecin based on mPEGylated alpha,-poly (L-aspartic acid)-camptothecin conjugate. Colloids Surf B Biointerfaces 2010;81(1):297-303
    • (2010) Colloids Surf B Biointerfaces , vol.81 , Issue.1 , pp. 297-303
    • Zhang, W.L.1    Huang, J.2    Fan, N.Q.3
  • 70
    • 79958788003 scopus 로고    scopus 로고
    • Polymeric micelles with water-insoluble drug as hydrophobic moiety for drug delivery
    • Li GL, Liu JY, Pang Y, et al. Polymeric micelles with water-insoluble drug as hydrophobic moiety for drug delivery. Biomacromolecules 2011;12(6):2016-26
    • (2011) Biomacromolecules , vol.12 , Issue.6 , pp. 2016-2026
    • Li, G.L.1    Liu, J.Y.2    Pang, Y.3
  • 71
    • 0027876078 scopus 로고
    • Critical micellization phenomena in block polyelectrolyte solutions
    • Astafieva I, Zhong XF, Eisenberg A. Critical micellization phenomena in block polyelectrolyte solutions. Macromolecules 1993;26(26):7339-52
    • (1993) Macromolecules , vol.26 , Issue.26 , pp. 7339-7352
    • Astafieva, I.1    Zhong, X.F.2    Eisenberg, A.3
  • 72
    • 0035387946 scopus 로고    scopus 로고
    • Salt effect on critical micelle concentrations of nonionic surfactants, N-acyl-N-methylglucamides (MEGA-n)
    • DOI 10.1006/jcis.2001.7503
    • Miyagishi S, Okada K, Asakawa T. Salt effect on critical micelle concentrations of nonionic surfactants, N-Acyl-N-methylglucamides (MEGA-n). J Colloid Interface Sci 2001;238(1):91-5 (Pubitemid 32896795)
    • (2001) Journal of Colloid and Interface Science , vol.238 , Issue.1 , pp. 91-95
    • Miyagishi, S.1    Okada, K.2    Asakawa, T.3
  • 73
    • 84856552388 scopus 로고    scopus 로고
    • A model for monomer and micellar concentrations in surfactant solutions: Application to conductivity, NMR, diffusion, and surface tension data
    • Al-Soufi W, Pineiro L, Novo M. A model for monomer and micellar concentrations in surfactant solutions: application to conductivity, NMR, diffusion, and surface tension data. J Colloid Interface Sci 2012;370(1):102-10
    • (2012) J Colloid Interface Sci , vol.370 , Issue.1 , pp. 102-110
    • Al-Soufi, W.1    Pineiro, L.2    Novo, M.3
  • 74
    • 80052939857 scopus 로고    scopus 로고
    • Aggregation behavior and interaction of an amphiphilic drug imipramine hydrochloride with cationic surfactant cetyltrimethylammonium bromide: Light scattering studies
    • Alam MS, Ghosh G, Mandal AB, Kabir ud D. Aggregation behavior and interaction of an amphiphilic drug imipramine hydrochloride with cationic surfactant cetyltrimethylammonium bromide: light scattering studies. Colloids Surf B Biointerfaces 2011;88(2):779-84
    • (2011) Colloids Surf B Biointerfaces , vol.88 , Issue.2 , pp. 779-784
    • Alam, M.S.1    Ghosh, G.2    Mandal, A.B.3    Kabir Ud, D.4
  • 75
    • 0025384405 scopus 로고
    • Fluorescence probe techniques used to study micelle formation in water-soluble block copolymers
    • Zhao CL, Winnik MA, Riess G, Croucher MD. Fluorescence probe techniques used to study micelle formation in water-soluble block copolymers. Langmuir 1990;6(2):514-16 (Pubitemid 20663816)
    • (1990) Langmuir , vol.6 , Issue.2 , pp. 514-516
    • Zhao C.-Le1    Winnik, M.A.2    Riess, G.3    Croucher, M.D.4
  • 76
    • 81355147508 scopus 로고    scopus 로고
    • The effects of polymeric nanostructure shape on drug delivery
    • Venkataraman S, Hedrick JL, Ong ZY, et al. The effects of polymeric nanostructure shape on drug delivery. Adv Drug Deliv Rev 2011;63(14-15):1228-46
    • (2011) Adv Drug Deliv Rev , vol.63 , Issue.14-15 , pp. 1228-1246
    • Venkataraman, S.1    Hedrick, J.L.2    Ong, Z.Y.3
  • 77
    • 78649810957 scopus 로고    scopus 로고
    • Advances in polymeric micelles for drug delivery and tumor targeting
    • Exhaustive review describing the progress regarding the targeting mechanisms of anticancer drugs to the tumor site using polymeric micelles
    • Kedar U, Phutane P, Shidhaye S, Kadam V. Advances in polymeric micelles for drug delivery and tumor targeting. Nanomedicine 2010;6(6):714-29 Exhaustive review describing the progress regarding the targeting mechanisms of anticancer drugs to the tumor site using polymeric micelles.
    • (2010) Nanomedicine , vol.6 , Issue.6 , pp. 714-729
    • Kedar, U.1    Phutane, P.2    Shidhaye, S.3    Kadam, V.4
  • 78
    • 79957691069 scopus 로고    scopus 로고
    • Physical and chemical stability of drug nanoparticles
    • Review describing the stability of drug nanoparticles dispersed in the liquid medium
    • Wu LB, Zhang J, Watanabe W. Physical and chemical stability of drug nanoparticles. Adv Drug Deliv Rev 2011;63(6):456-69 Review describing the stability of drug nanoparticles dispersed in the liquid medium.
    • (2011) Adv Drug Deliv Rev , vol.63 , Issue.6 , pp. 456-469
    • Wu, L.B.1    Zhang, J.2    Watanabe, W.3
  • 79
    • 0022858683 scopus 로고
    • A new concept for macromolecular therapeutics in cancer chemotherapy: Mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs
    • Matsumura Y, Maeda H. A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs. Cancer Res 1986;46(12 Pt 1):6387-92 One of the initial reviews introducing the EPR effect as a passive targeting strategy for macromolecular drugs. (Pubitemid 17221789)
    • (1986) Cancer Research , vol.46 , Issue.12 I , pp. 6387-6392
    • Matsumura, Y.1    Maeda, H.2
  • 80
    • 0028346185 scopus 로고
    • Enhanced tumor accumulation and prolonged circulation times of micelle-forming poly (ethylene oxide-aspartate) block copolymer-adriamycin conjugates
    • Kwon G, Suwa S, Yokoyama M, et al. Enhanced tumor accumulation and prolonged circulation times of micelle-forming poly (ethylene oxide-aspartate) block copolymer-adriamycin conjugates. J Control Release 1994;29(1-2):17-23
    • (1994) J Control Release , vol.29 , Issue.1-2 , pp. 17-23
    • Kwon, G.1    Suwa, S.2    Yokoyama, M.3
  • 81
    • 33747762229 scopus 로고    scopus 로고
    • Exploiting the enhanced permeability and retention effect for tumor targeting
    • DOI 10.1016/j.drudis.2006.07.005, PII S1359644606002716
    • Lyer AK, Khaled G, Fang J, Maeda H. Exploiting the enhanced permeability and retention effect for tumor targeting. Drug Discov Today 2006;11(17-18):812- 18 (Pubitemid 44280021)
    • (2006) Drug Discovery Today , vol.11 , Issue.17-18 , pp. 812-818
    • Iyer, A.K.1    Khaled, G.2    Fang, J.3    Maeda, H.4
  • 82
    • 79953054576 scopus 로고    scopus 로고
    • The EPR effect: Unique features of tumor blood vessels for drug delivery, factors involved, and limitations and augmentation of the effect
    • Fang J, Nakamura H, Maeda H. The EPR effect: unique features of tumor blood vessels for drug delivery, factors involved, and limitations and augmentation of the effect. Adv Drug Deliv Rev 2011;63(3):136-51
    • (2011) Adv Drug Deliv Rev , vol.63 , Issue.3 , pp. 136-151
    • Fang, J.1    Nakamura, H.2    Maeda, H.3
  • 83
    • 79953048071 scopus 로고    scopus 로고
    • Tumor delivery of macromolecular drugs based on the EPR effect
    • Torchilin V. Tumor delivery of macromolecular drugs based on the EPR effect. Adv Drug Deliv Rev 2011;63(3):131-5
    • (2011) Adv Drug Deliv Rev , vol.63 , Issue.3 , pp. 131-135
    • Torchilin, V.1
  • 84
    • 70349386390 scopus 로고    scopus 로고
    • Biodegradable amphiphilic polymer-drug conjugate micelles
    • Excellent review describing the biodegradable amphiphilic polymer--drug conjugate micelles
    • Hu XL, Jing XB. Biodegradable amphiphilic polymer-drug conjugate micelles. Expert Opin Drug Deliv 2009;6(10):1079-90 Excellent review describing the biodegradable amphiphilic polymer--drug conjugate micelles.
    • (2009) Expert Opin Drug Deliv , vol.6 , Issue.10 , pp. 1079-1090
    • Hu, X.L.1    Jing, X.B.2
  • 85
    • 66149116471 scopus 로고    scopus 로고
    • Ligand-based targeted therapy for cancer tissue
    • Das M, Mohanty C, Sahoo SK. Ligand-based targeted therapy for cancer tissue. Expert Opin Drug Deliv 2009;6(3):285-304
    • (2009) Expert Opin Drug Deliv , vol.6 , Issue.3 , pp. 285-304
    • Das, M.1    Mohanty, C.2    Sahoo, S.K.3
  • 87
    • 55849099605 scopus 로고    scopus 로고
    • Active targeting schemes for nanoparticle systems in cancer therapeutics
    • Byrne JD, Betancourt T, Brannon-Peppas L. Active targeting schemes for nanoparticle systems in cancer therapeutics. Adv Drug Deliv Rev 2008;60(15):1615-26
    • (2008) Adv Drug Deliv Rev , vol.60 , Issue.15 , pp. 1615-1626
    • Byrne, J.D.1    Betancourt, T.2    Brannon-Peppas, L.3
  • 88
    • 27944455140 scopus 로고    scopus 로고
    • Folate receptor-mediated drug targeting: From therapeutics to diagnostics
    • DOI 10.1002/jps.20457
    • Hilgenbrink AR, Low PS. Folate receptor-mediated drug targeting: from therapeutics to diagnostics. J Pharm Sci 2005;94(10):2135-46 (Pubitemid 41665275)
    • (2005) Journal of Pharmaceutical Sciences , vol.94 , Issue.10 , pp. 2135-2146
    • Hilgenbrink, A.R.1    Low, P.S.2
  • 89
    • 79954629518 scopus 로고    scopus 로고
    • Novel folated and non-folated pullulan bioconjugates for anticancer drug delivery
    • Scomparin A, Salmaso S, Bersani S, et al. Novel folated and non-folated pullulan bioconjugates for anticancer drug delivery. Eur J Pharm Sci 2011;42(5):547-58
    • (2011) Eur J Pharm Sci , vol.42 , Issue.5 , pp. 547-558
    • Scomparin, A.1    Salmaso, S.2    Bersani, S.3
  • 90
    • 0037130252 scopus 로고    scopus 로고
    • Doxorubicin-conjugated biodegradable polymeric micelles having acid-cleavable linkages
    • DOI 10.1016/S0168-3659(02)00088-3, PII S0168365902000883
    • Yoo HS, Lee EA, Park TG. Doxorubicin-conjugated biodegradable polymeric micelles having acid-cleavable linkages. J Control Release 2002;82(1):17-27 (Pubitemid 34775044)
    • (2002) Journal of Controlled Release , vol.82 , Issue.1 , pp. 17-27
    • Yoo, H.S.1    Lee, E.A.2    Park, T.G.3
  • 91
    • 70349979533 scopus 로고    scopus 로고
    • Polymer therapeutics: Clinical applications and challenges for development
    • Vicent MJ, Ringsdorf H, Duncan R. Polymer therapeutics: clinical applications and challenges for development. Adv Drug Deliv Rev 2009;61(13):1117-20
    • (2009) Adv Drug Deliv Rev , vol.61 , Issue.13 , pp. 1117-1120
    • Vicent, M.J.1    Ringsdorf, H.2    Duncan, R.3
  • 92
    • 79960942844 scopus 로고    scopus 로고
    • Polymer therapeutics as nanomedicines: New perspectives
    • Duncan R. Polymer therapeutics as nanomedicines: new perspectives. Curr Opin Biotechnol 2011;22(4):492-501
    • (2011) Curr Opin Biotechnol , vol.22 , Issue.4 , pp. 492-501
    • Duncan, R.1
  • 93
    • 34547797860 scopus 로고    scopus 로고
    • Anticancer polymeric nanomedicines
    • DOI 10.1080/15583720701455079, PII 781099696
    • Tong R, Cheng JJ. Anticancer polymeric nanomedicines. Polym Rev 2007;47(3):345-81 (Pubitemid 47240845)
    • (2007) Polymer Reviews , vol.47 , Issue.3 , pp. 345-381
    • Tong, R.1    Cheng, J.2
  • 94
    • 77956073874 scopus 로고    scopus 로고
    • Polymer--drug conjugates for novel molecular targets
    • Sanchis J, Canal F, Lucas R, Vicent MJ. Polymer--drug conjugates for novel molecular targets. Nanomedicine 2010;5(6):915-35
    • (2010) Nanomedicine , vol.5 , Issue.6 , pp. 915-935
    • Sanchis, J.1    Canal, F.2    Lucas, R.3    Vicent, M.J.4
  • 95
    • 79251478025 scopus 로고    scopus 로고
    • Novel free paclitaxel-loaded poly(L-gamma-glutamylglutamine)-paclitaxel nanoparticles
    • Yang DB, Van S, Jiang XG, Yu L. Novel free paclitaxel-loaded poly(L-gamma-glutamylglutamine)-paclitaxel nanoparticles. Int J Nanomed 2011;6:85-91
    • (2011) Int J Nanomed , vol.6 , pp. 85-91
    • Yang, D.B.1    Van, S.2    Jiang, X.G.3    Yu, L.4
  • 96
    • 84862737050 scopus 로고    scopus 로고
    • Synthesis, characterization, and in vivo efficacy evaluation of PGG-docetaxel conjugate for potential cancer chemotherapy
    • Yang DB, Van S, Shu YY, et al. Synthesis, characterization, and in vivo efficacy evaluation of PGG-docetaxel conjugate for potential cancer chemotherapy. Int J Nanomed 2012;7:581-9
    • (2012) Int J Nanomed , vol.7 , pp. 581-589
    • Yang, D.B.1    Van, S.2    Shu, Y.Y.3
  • 97
    • 80054807276 scopus 로고    scopus 로고
    • Hyaluronic acid-paclitaxel conjugate inhibits growth of human squamous cell carcinomas of the head and neck via a hyaluronic acid-mediated mechanism
    • Galer CE, Sano D, Ghosh SC, et al. Hyaluronic acid-paclitaxel conjugate inhibits growth of human squamous cell carcinomas of the head and neck via a hyaluronic acid-mediated mechanism. Oral Oncol 2011;47(11):1039-47
    • (2011) Oral Oncol , vol.47 , Issue.11 , pp. 1039-1047
    • Galer, C.E.1    Sano, D.2    Ghosh, S.C.3
  • 98
    • 77949269580 scopus 로고    scopus 로고
    • The use of amino acid linkers in the conjugation of paclitaxel with hyaluronic acid as drug delivery system: Synthesis, self-assembled property, drug release, and in vitro efficiency
    • Xin DC, Wang Y, Xiang JN. The use of amino acid linkers in the conjugation of paclitaxel with hyaluronic acid as drug delivery system: synthesis, self-assembled property, drug release, and in vitro efficiency. Pharm Res 2010;27(2):380-9
    • (2010) Pharm Res , vol.27 , Issue.2 , pp. 380-389
    • Xin, D.C.1    Wang, Y.2    Xiang, J.N.3
  • 99
    • 79955476046 scopus 로고    scopus 로고
    • Conjugation of curcumin onto hyaluronic acid enhances its aqueous solubility and stability
    • Manju S, Sreenivasan K. Conjugation of curcumin onto hyaluronic acid enhances its aqueous solubility and stability. J Colloid Interface Sci 2011;359(1):318-25
    • (2011) J Colloid Interface Sci , vol.359 , Issue.1 , pp. 318-325
    • Manju, S.1    Sreenivasan, K.2
  • 100
    • 61449171880 scopus 로고    scopus 로고
    • Heparin-paclitaxel conjugates using mixed anhydride as intermediate: Synthesis, influence of polymer structure on drug release, anticoagulant activity and in vitro efficiency
    • Wang Y, Xin DC, Liu KJ, Xiang JN. Heparin-paclitaxel conjugates using mixed anhydride as intermediate: synthesis, influence of polymer structure on drug release, anticoagulant activity and in vitro efficiency. Pharm Res 2009;26(4):785-93
    • (2009) Pharm Res , vol.26 , Issue.4 , pp. 785-793
    • Wang, Y.1    Xin, D.C.2    Liu, K.J.3    Xiang, J.N.4
  • 101
    • 0028906044 scopus 로고
    • Studies on the mechanism of action of an MTX-HSA-MoAb conjugate
    • Fitzpatrick JJ, Garnett MC. Studies on the mechanism of action of an MTX-HSA-MoAb conjugate. Anticancer Drug Des 1995;10(1):11-24
    • (1995) Anticancer Drug des , vol.10 , Issue.1 , pp. 11-24
    • Fitzpatrick, J.J.1    Garnett, M.C.2
  • 102
    • 34347354414 scopus 로고    scopus 로고
    • Albumin-binding prodrugs of camptothecin and doxorubicin with an Ala-Leu-Ala-Leu-Linker that are cleaved by cathepsin B: Synthesis and antitumor efficacy
    • DOI 10.1021/bc0602735
    • Schmid B, Chung DE, Warnecke A, et al. Albumin-binding prodrugs of camptothecin and doxorubicin with an Ala-Leu-Ala-Leu-linker that are cleaved by cathepsin B: synthesis and antitumor efficacy. Bioconjug Chem 2007;18(3):702-16 (Pubitemid 47010789)
    • (2007) Bioconjugate Chemistry , vol.18 , Issue.3 , pp. 702-716
    • Schmid, B.1    Chung, D.-E.2    Warnecke, A.3    Fichtner, I.4    Kratz, F.5
  • 103
    • 77952160665 scopus 로고    scopus 로고
    • In vitro evaluation of a Folate-bovine serum albumin-doxorubicin conjugate
    • Qu XL, Yang C, Zhang J, et al. In vitro evaluation of a Folate-bovine serum albumin-doxorubicin conjugate. J Drug Target 2010;18(5):351-61
    • (2010) J Drug Target , vol.18 , Issue.5 , pp. 351-361
    • Qu, X.L.1    Yang, C.2    Zhang, J.3
  • 104
    • 80053004416 scopus 로고    scopus 로고
    • Targeted albumin-based nanoparticles for delivery of amphipathic drugs
    • Xu R, Fisher M, Juliano RL. Targeted albumin-based nanoparticles for delivery of amphipathic drugs. Bioconjug Chem 2011;22(5):870-8
    • (2011) Bioconjug Chem , vol.22 , Issue.5 , pp. 870-878
    • Xu, R.1    Fisher, M.2    Juliano, R.L.3
  • 105
    • 57449109348 scopus 로고    scopus 로고
    • Synthesis, self-assembly in water, and cytotoxicity of MPEG-block-PLLA/DX conjugates
    • Xie ZG, Lu TC, Chen XS, et al. Synthesis, self-assembly in water, and cytotoxicity of MPEG-block-PLLA/DX conjugates. J Biomed Mater Res A 2009;88(1):238-45
    • (2009) J Biomed Mater Res A , vol.88 , Issue.1 , pp. 238-245
    • Xie, Z.G.1    Lu, T.C.2    Chen, X.S.3
  • 106
    • 56749178274 scopus 로고    scopus 로고
    • A biodegradable diblock copolymer poly (ethylene glycol)-block-poly(L- lactide-co-2-methyl-2-carboxyl-propylene carbonate): Docetaxel and RGD conjugation
    • Xie ZG, Hu XL, Chen XS, et al. A biodegradable diblock copolymer poly (ethylene glycol)-block-poly(L-lactide-co-2-methyl-2-carboxyl-propylene carbonate): docetaxel and RGD conjugation. J Appl Polym Sci 2008;110:2961-70
    • (2008) J Appl Polym Sci , vol.110 , pp. 2961-2970
    • Xie, Z.G.1    Hu, X.L.2    Chen, X.S.3
  • 107
    • 77955563613 scopus 로고    scopus 로고
    • Biodegradable block copolymer-doxorubicin conjugates via different linkages: Preparation, characterization, and in vitro evaluation
    • Hu XL, Liu S, Huang YB, et al. Biodegradable block copolymer-doxorubicin conjugates via different linkages: preparation, characterization, and in vitro evaluation. Biomacromolecules 2010;11(8):2094-102
    • (2010) Biomacromolecules , vol.11 , Issue.8 , pp. 2094-2102
    • Hu, X.L.1    Liu, S.2    Huang, Y.B.3
  • 108
    • 34547214431 scopus 로고    scopus 로고
    • Triblock poly(lactic acid)-b-poly(ethylene glycol)-b-poly(lactic acid)/paclitaxel conjugates: Synthesis, micellization, and cytotoxicity
    • Xie ZG, Lu TC, Chen XS, et al. Triblock poly(lactic acid)-b-poly(ethylene glycol)-b-poly(lactic acid)/paclitaxel conjugates: synthesis, micellization, and cytotoxicity. J Appl Polym Sci 2007;105:2271-9
    • (2007) J Appl Polym Sci , vol.105 , pp. 2271-2279
    • Xie, Z.G.1    Lu, T.C.2    Chen, X.S.3
  • 110
    • 26644464129 scopus 로고    scopus 로고
    • Multifunctional polymeric micelles with folate-mediated cancer cell targeting and pH-triggered drug releasing properties for active intracellular drug delivery
    • DOI 10.1039/b500266d
    • Bae Y, Jang WD, Nishiyama N, et al. Multifunctional polymeric micelles with folate-mediated cancer cell targeting and pH-triggered drug releasing properties for active intracellular drug delivery. Mol Biosyst 2005;1(3):242-50 (Pubitemid 41442434)
    • (2005) Molecular BioSystems , vol.1 , Issue.3 , pp. 242-250
    • Bae, Y.1    Jang, W.-D.2    Nishiyama, N.3    Fukushima, S.4    Kataoka, K.5
  • 111
    • 34547161854 scopus 로고    scopus 로고
    • In vivo antitumor activity of the folate-conjugated pH-sensitive polymeric micelle selectively releasing adriamycin in the intracellular acidic compartments
    • DOI 10.1021/bc060401p
    • Bae Y, Nishiyama N, Kataoka K. In vivo antitumor activity of the folate-conjugated pH-sensitive polymeric micelle selectively releasing adriamycin in the intracellular acidic compartments. Bioconjug Chem 2007;18(4):1131-9 (Pubitemid 47122634)
    • (2007) Bioconjugate Chemistry , vol.18 , Issue.4 , pp. 1131-1139
    • Bae, Y.1    Nishiyama, N.2    Kataoka, K.3
  • 112
    • 34548709201 scopus 로고    scopus 로고
    • Significant enhancement of antitumor activity and bioavailability of intracellular pH-sensitive polymeric micelles by folate conjugation
    • Bae Y, Kataoka K. Significant enhancement of antitumor activity and bioavailability of intracellular pH-sensitive polymeric micelles by folate conjugation. J Control Release 2006;116(2):e49-50
    • (2006) J Control Release , vol.116 , Issue.2
    • Bae, Y.1    Kataoka, K.2
  • 113
    • 70549112065 scopus 로고    scopus 로고
    • Fabrication of nanomicelle with enhanced solubility and stability of camptothecin based on alpha,-poly [(N-carboxybutyl)-L-aspartamide]-camptothecin conjugate
    • Fan NQ, Duan KR, Wang CY, et al. Fabrication of nanomicelle with enhanced solubility and stability of camptothecin based on alpha,-poly [(N-carboxybutyl)-L-aspartamide]-camptothecin conjugate. Colloids Surf B Biointerfaces 2010;75(2):543-9
    • (2010) Colloids Surf B Biointerfaces , vol.75 , Issue.2 , pp. 543-549
    • Fan, N.Q.1    Duan, K.R.2    Wang, C.Y.3
  • 114
    • 13844269029 scopus 로고    scopus 로고
    • Polymeric micellar pH-sensitive drug delivery system for doxorubicin
    • DOI 10.1016/j.jconrel.2004.11.017, PII S0168365904005802
    • Hruby M, Konak C, Ulbrich K. Polymeric micellar pH-sensitive drug delivery system for doxorubicin. J Control Release 2005;103(1):137-48 (Pubitemid 40248568)
    • (2005) Journal of Controlled Release , vol.103 , Issue.1 , pp. 137-148
    • Hruby, M.1    Konak, C.2    Ulbrich, K.3
  • 115
    • 39749152136 scopus 로고    scopus 로고
    • Synthesis, characterization, antitumor activity of pluronic mimicking copolymer micelles conjugated with doxorubicin via acid-cleavable linkage
    • DOI 10.1021/bc700382z
    • Lee Y, Park SY, Mok H, Park TG. Synthesis, characterization, antitumor activity of pluronic mimicking copolymer micelles conjugated with doxorubicin via acid-cleavable linkage. Bioconjug Chem 2008;19(2):525-31 (Pubitemid 351294925)
    • (2008) Bioconjugate Chemistry , vol.19 , Issue.2 , pp. 525-531
    • Lee, Y.1    Sung, Y.P.2    Mok, H.3    Tae, G.P.4
  • 116
    • 80053131602 scopus 로고    scopus 로고
    • Characterization and anti-tumor activity of chemical conjugation of doxorubicin in polymeric micelles (DOX-P) in vitro
    • Zhao YZ, Sun CZ, Lu CT, et al. Characterization and anti-tumor activity of chemical conjugation of doxorubicin in polymeric micelles (DOX-P) in vitro. Cancer Lett 2011;311(2):187-94
    • (2011) Cancer Lett , vol.311 , Issue.2 , pp. 187-194
    • Zhao, Y.Z.1    Sun, C.Z.2    Lu, C.T.3


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