Synthesis, self-assembly in water, and cytotoxicity of MPEG-block-PLLA/DX conjugates

Journal of Biomedical Materials Research - Part A

Volumn 88, Issue 1, 2009, Pages 238-245

  Xie, Zhigang ^a,b   Lu, Tiancheng ^a,b   Chen, Xuesi ^a   Zheng, Yonghui ^a   Jing, Xiabin ^a  

^a CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY   (China)

^b UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

Author keywords

Antitumor; Conjugate; MPEG PLLA

Indexed keywords

COLLOIDS; CONTROLLED DRUG DELIVERY; COPOLYMERIZATION; DRUG INTERACTIONS; DRUG PRODUCTS; ETHYLENE; ETHYLENE GLYCOL; GLYCOLS; NUCLEAR MAGNETIC RESONANCE; ORGANIC POLYMERS; POLYETHYLENE GLYCOLS; POLYETHYLENE OXIDES; POLYMERS;

ANTINEOPLASTIC DRUGS; ANTITUMOR; ANTITUMOR ACTIVITIES; AQUEOUS SOLUTIONS; CANCER CELLS; CONJUGATE; DISPLACEMENT METHODS; DOCETAXEL; DRUG CONTENTS; MPEG-PLLA; MTT ASSAYS; POLIES (LLACTIDE); POLY(ETHYLENE GLYCOL); SELF-ASSEMBLY; SIDE EFFECTS; SIZE AND SIZE DISTRIBUTIONS; SUCCINIC ANHYDRIDES;

MOTION PICTURE EXPERTS GROUP STANDARDS;

COPOLYMER; DOCETAXEL; MACROGOL; MONOMETHOXYPOLY(ETHOXYLENE GLYCOL) BLOCK POLY(LACTIDE) DOCETAXEL CONJUGATE; POLYLACTIDE; SUCCINIC ANHYDRIDE; UNCLASSIFIED DRUG; WATER;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; DRUG CONJUGATION; DRUG FORMULATION; DRUG STRUCTURE; DRUG SYNTHESIS; HELA CELL; HUMAN; HUMAN CELL; LIGHT SCATTERING; MOLECULAR WEIGHT; PARTICLE SIZE; PROTON NUCLEAR MAGNETIC RESONANCE; TRANSMISSION ELECTRON MICROSCOPY;

ANTINEOPLASTIC AGENTS; DRUG SCREENING ASSAYS, ANTITUMOR; HELA CELLS; HUMANS; LACTATES; MICELLES; MOLECULAR STRUCTURE; MOLECULAR WEIGHT; POLYETHYLENE GLYCOLS; POLYMERS; TAXOIDS; WATER;

EID: 57449109348     PISSN: 15493296     EISSN: 15524965     Source Type: Journal    
DOI: 10.1002/jbm.a.31861     Document Type: Article

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