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Volumn 6, Issue SUPPL. 2, 2004, Pages

CT-2103: A novel macromolecular taxane with potential advantages compared with conventional taxanes

Author keywords

Apoptosis; Macromolecular drug conjugate; Mitotic arrest; Neuropathy; Paclitaxel

Indexed keywords

ANTINEOPLASTIC AGENT; CARBOPLATIN; DOCETAXEL; GLYCOPROTEIN P; PACLITAXEL; PACLITAXEL POLIGLUMEX; PLATINUM; POLYMER; TAXANE DERIVATIVE; UNCLASSIFIED DRUG;

EID: 12744269417     PISSN: 15257304     EISSN: None     Source Type: Journal    
DOI: 10.3816/CLC.2004.s.020     Document Type: Article
Times cited : (35)

References (23)
  • 1
    • 0033840307 scopus 로고    scopus 로고
    • Chemotherapy of advanced non small cell lung cancer in the elderly: An update
    • Gridelli C. Chemotherapy of advanced non small cell lung cancer in the elderly: an update. Crit Rev Oncol Hematol 2000; 35:219-225.
    • (2000) Crit. Rev. Oncol. Hematol. , vol.35 , pp. 219-225
    • Gridelli, C.1
  • 2
    • 0037106514 scopus 로고    scopus 로고
    • Chemotherapy for advanced non-small-cell lung cancer: Who, what, when, why?
    • Bunn PA Jr. Chemotherapy for advanced non-small-cell lung cancer: who, what, when, why? J Clin Oncol 2002; 20:23S-33S.
    • (2002) J. Clin. Oncol. , vol.20
    • Bunn Jr., P.A.1
  • 3
    • 0028708677 scopus 로고
    • Taxol (paclitaxel): Mechanisms of action
    • Horwitz SB. Taxol (paclitaxel): mechanisms of action. Ann Oncol 1994; 5 (suppl 6):S3-S6.
    • (1994) Ann. Oncol. , vol.5 , Issue.SUPPL. 6
    • Horwitz, S.B.1
  • 4
    • 0037619168 scopus 로고    scopus 로고
    • Poly-(L)-glucamic acid-paclitaxel (CT-2103) [XYOTAX], a biodegradable polymeric drug conjugate: Characterization, preclinical pharmacology, and preliminary clinical data
    • Singer JW, Baker B, De Vries P, et al. Poly-(L)-glucamic acid-paclitaxel (CT-2103) [XYOTAX], a biodegradable polymeric drug conjugate: characterization, preclinical pharmacology, and preliminary clinical data. Adv Exp Med Biol 2003; 519:81-99.
    • (2003) Adv. Exp. Med. Biol. , vol.519 , pp. 81-99
    • Singer, J.W.1    Baker, B.2    De Vries, P.3
  • 5
    • 0038387390 scopus 로고    scopus 로고
    • The dawning era of polymer therapeutics
    • Duncan R. The dawning era of polymer therapeutics. Nat Rev Drug Discov 2003; 2:347-360.
    • (2003) Nat. Rev. Drug Discov. , vol.2 , pp. 347-360
    • Duncan, R.1
  • 6
    • 0034880214 scopus 로고    scopus 로고
    • The drawbacks and advantages of vehicle selection for drug formulation
    • Gelderblom H, Verweij J, Nooter K, et al. the drawbacks and advantages of vehicle selection for drug formulation. Eur J Cancer 2001; 37:1590-1598.
    • (2001) Eur. J. Cancer , vol.37 , pp. 1590-1598
    • Gelderblom, H.1    Verweij, J.2    Nooter, K.3
  • 8
    • 0242288519 scopus 로고    scopus 로고
    • Macromolecular therapeutics: Advantages and prospects with special emphasis on solid tumour targeting
    • Greish K, Fang J, Inutsuka T, et al. Macromolecular therapeutics: advantages and prospects with special emphasis on solid tumour targeting. Clin Pharmacokinet 2003; 42:1089-1105.
    • (2003) Clin. Pharmacokinet. , vol.42 , pp. 1089-1105
    • Greish, K.1    Fang, J.2    Inutsuka, T.3
  • 9
    • 0022858683 scopus 로고
    • A new concept for macromolecular therapeutics in cancer chemotherapy: Mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs
    • Matsumura Y, Maeda H. A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs. Cancer Res 1986; 46:6387-6392.
    • (1986) Cancer Res. , vol.46 , pp. 6387-6392
    • Matsumura, Y.1    Maeda, H.2
  • 10
    • 0038387390 scopus 로고    scopus 로고
    • The dawning era of polymer therapeutics
    • Duncan R. The dawning era of polymer therapeutics. Nat Rev Drug Discov 2003; 2:347-360.
    • (2003) Nat. Rev. Drug Discov. , vol.2 , pp. 347-360
    • Duncan, R.1
  • 11
    • 0038264340 scopus 로고    scopus 로고
    • Membrane dynamics and the biogenesis of lysosomes
    • Luzio JP, Poupon V, Lindsay MR, et al. Membrane dynamics and the biogenesis of lysosomes. Mol Membr Biol 2003; 20:141-154.
    • (2003) Mol. Membr. Biol. , vol.20 , pp. 141-154
    • Luzio, J.P.1    Poupon, V.2    Lindsay, M.R.3
  • 12
    • 0036224915 scopus 로고    scopus 로고
    • Inhibitors of multidrug resistance to antitumor agents (MDR)
    • Avendano C, Menendez JC. Inhibitors of multidrug resistance to antitumor agents (MDR). Curr Med Chem 2002; 9:159-193.
    • (2002) Curr. Med. Chem. , vol.9 , pp. 159-193
    • Avendano, C.1    Menendez, J.C.2
  • 13
    • 0142156106 scopus 로고    scopus 로고
    • Comparing the relationship of Taxol-based chemotherapy response with P-glycoprotein and lung resistance-related protein expression in non-small cell lung cancer
    • Chico JF, Liang JA, Hsu WH, et al. Comparing the relationship of Taxol-based chemotherapy response with P-glycoprotein and lung resistance-related protein expression in non-small cell lung cancer. Lung 2003; 181:267-273.
    • (2003) Lung , vol.181 , pp. 267-273
    • Chico, J.F.1    Liang, J.A.2    Hsu, W.H.3
  • 14
    • 0036903656 scopus 로고    scopus 로고
    • Relationship between chemotherapy response of small cell lung cancer and P-glycoprotein or multidrug resistance-related protein expression
    • Hsia TC, Lin CC, Wang JJ, et al. Relationship between chemotherapy response of small cell lung cancer and P-glycoprotein or multidrug resistance-related protein expression. Lung 2002; 180:173-179.
    • (2002) Lung , vol.180 , pp. 173-179
    • Hsia, T.C.1    Lin, C.C.2    Wang, J.J.3
  • 16
    • 12744274140 scopus 로고    scopus 로고
    • Xyotax™ (paclitaxel poliglumex; CT-2103). Pharmacokinetic evidence for an enhanced permeability and retention effect
    • (Abstract #385)
    • Bernareggi A, Oldham F, Barone C. Xyotax™ (paclitaxel poliglumex; CT-2103). Pharmacokinetic evidence for an enhanced permeability and retention effect. Ann Oncol 2004; 15(suppl 3): iii103 (Abstract #385).
    • (2004) Ann. Oncol. , vol.15 , Issue.SUPPL. 3
    • Bernareggi, A.1    Oldham, F.2    Barone, C.3
  • 17
    • 3542997131 scopus 로고    scopus 로고
    • Phase 2 study of first line chemotherapy using CT-2103 (XYOTAX) in patients with non-small cell lung cancer who are > 69 years of age or who have performance status (PS) = 2
    • (Abstract #806)
    • Bodkin D, Neubauer M, Bolton MG. Phase 2 study of first line chemotherapy using CT-2103 (XYOTAX) in patients with non-small cell lung cancer who are > 69 years of age or who have performance status (PS) = 2. Eur J Cancer 2003; 1 (suppl):S242 (Abstract #806).
    • (2003) Eur. J. Cancer , vol.1 , Issue.SUPPL.
    • Bodkin, D.1    Neubauer, M.2    Bolton, M.G.3
  • 18
    • 0003275345 scopus 로고    scopus 로고
    • Single-agent (SA) versus combination chemotherapy (CC) in advanced non-small cell lung cancer (NSCLC): A CALGB randomized trial of efficacy, quality of life (QOL), and cost-effectiveness
    • (Abstract #2)
    • Lilenbaum R, Herndon J, List M, et al. Single-agent (SA) versus combination chemotherapy (CC) in advanced non-small cell lung cancer (NSCLC): a CALGB randomized trial of efficacy, quality of life (QOL), and cost-effectiveness. Proc Am Soc Clin Oncol 2002; 21: 1a (Abstract #2).
    • (2002) Proc. Am. Soc. Clin. Oncol. , vol.21
    • Lilenbaum, R.1    Herndon, J.2    List, M.3
  • 19
    • 4043180858 scopus 로고    scopus 로고
    • Phase 1 study of Xyotax (CT-2103) and carboplatin in patients with solid tumors
    • (Abstract #566)
    • Nemunaitis J. Phase 1 study of Xyotax (CT-2103) and carboplatin in patients with solid tumors. Eur J Cancer 2003; 1(suppl):S171 (Abstract #566).
    • (2003) Eur. J. Cancer , vol.1 , Issue.SUPPL.
    • Nemunaitis, J.1
  • 20
    • 0034095853 scopus 로고    scopus 로고
    • Randomized phase III trial of docetaxel versus vinorelbine or ifosfamide in patients with advanced non-small-cell lung cancer previously treated with platinum-containing chemotherapy regimens
    • The TAX 320 Non-Small Cell Lung Cancer Study Group
    • Fossella FV, DeVore R, Kerr RN, et al. Randomized phase III trial of docetaxel versus vinorelbine or ifosfamide in patients with advanced non-small-cell lung cancer previously treated with platinum-containing chemotherapy regimens. The TAX 320 Non-Small Cell Lung Cancer Study Group. J Clin Oncol 2000; 18:2354-2362.
    • (2000) J. Clin. Oncol. , vol.18 , pp. 2354-2362
    • Fossella, F.V.1    DeVore, R.2    Kerr, R.N.3
  • 21
    • 12744278961 scopus 로고    scopus 로고
    • CT-2103 (XYOTAX) in patients with recurrent epithelial ovarian, fallopian tube, or primary peritoneal carcinoma: Results of a phase II study
    • Sabbatini P, Aghajanian C, Dizon D, et al. CT-2103 (XYOTAX) in patients with recurrent epithelial ovarian, fallopian tube, or primary peritoneal carcinoma: results of a phase II study. J Clin Oncol 2004; 22:4523-4531.
    • (2004) J. Clin. Oncol. , vol.22 , pp. 4523-4531
    • Sabbatini, P.1    Aghajanian, C.2    Dizon, D.3
  • 22
    • 3543011323 scopus 로고    scopus 로고
    • Dilemmas in management: The controversial role of chemotherapy in PS 2 advanced NSCLC and the potential role of CT-2103 (Xyotax)
    • Langer CJ. Dilemmas in management: the controversial role of chemotherapy in PS 2 advanced NSCLC and the potential role of CT-2103 (Xyotax). Oncologist 2004; 9:398-405.
    • (2004) Oncologist , vol.9 , pp. 398-405
    • Langer, C.J.1
  • 23
    • 3543000150 scopus 로고    scopus 로고
    • Phase 1 study of CT-2103/cisplatin in solid tumors
    • (Abstract #554)
    • Skubitz K, Kudelka A, Bolton MG. Phase 1 study of CT-2103/cisplatin in solid tumors. Eur J Cancer 2003; 1(suppl :S168 (Abstract #554).
    • (2003) Eur. J. Cancer , vol.1 , Issue.SUPPL.
    • Skubitz, K.1    Kudelka, A.2    Bolton, M.G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.