Biodegradable block copolymer-doxorubicin conjugates via different linkages: Preparation, characterization, and in vitro evaluation

Biomacromolecules

Volumn 11, Issue 8, 2010, Pages 2094-2102

  Hu, Xiuli ^a   Liu, Shi ^a   Huang, Yubin ^a   Chen, Xuesi ^a   Jing, Xiabin ^a  

^a CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ACID-LABILE; BIODEGRADABLE BLOCK COPOLYMERS; CANCER CELLS; CELL APOPTOSIS; CORE SHELL STRUCTURE; DOXORUBICIN; DOXORUBICIN CONJUGATES; DRUG MOLECULES; FLOW-CYTOMETRIC ANALYSIS; FOLIC ACIDS; HYDRAZONES; IN-VITRO; IN-VITRO EVALUATION; LACTIDES; METHOXY; MIXED MICELLES; NANOCARRIERS; OVARIAN CANCER CELLS; PH-DEPENDENT; PH-SENSITIVITY; RELEASE BEHAVIORS; TWO-COMPONENT;

BLOCK COPOLYMERS; CELL CULTURE; CELL DEATH; CONTROLLED DRUG DELIVERY; COPOLYMERIZATION; ETHYLENE; ETHYLENE GLYCOL; FLOW CYTOMETRY; MOTION PICTURE EXPERTS GROUP STANDARDS; ORGANIC ACIDS; ORGANIC POLYMERS; PLASTIC PRODUCTS; POLYETHYLENE GLYCOLS; POLYETHYLENE OXIDES;

MICELLES;

CARBAMIC ACID; COPOLYMER; DOXORUBICIN; FOLIC ACID; HYDRAZONE DERIVATIVE; METHOXYPOLY(ETHYLENE GLYCOL) BLOCK POLY(LACTIDE CO 2,2 DIHYDROXYMETHYLPROPYLENE CARBONATE); NANOCARRIER; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; BIODEGRADABILITY; CANCER CELL; CONJUGATE; DRUG CONJUGATION; DRUG RELEASE; EVALUATION; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IN VITRO STUDY; INTERNALIZATION; MICELLE; MOLECULAR SIZE; PH; PRIORITY JOURNAL;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL LINE, TUMOR; CHROMATOGRAPHY, GEL; DOXORUBICIN; DRUG SCREENING ASSAYS, ANTITUMOR; FLOW CYTOMETRY; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MICROSCOPY, ELECTRON, TRANSMISSION; POLYMERS;

EID: 77955563613     PISSN: 15257797     EISSN: 15264602     Source Type: Journal    
DOI: 10.1021/bm100458n     Document Type: Article

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