메뉴 건너뛰기




Volumn 25, Issue 6, 2012, Pages 1176-1191

Erratum: Potential of the NBP method for the study of alkylation mechanisms: NBP as a DNA-model (Chemical Research in Toxicology (2012) 25:6 (1176-1191) DOI: 10.1021/tx300065v);Potential of the NBP method for the study of alkylation mechanisms: NBP as a DNA-model

Author keywords

[No Author keywords available]

Indexed keywords

ALKYLATING AGENT; BENZENEDIAZONIUM; CARCINOGEN; DIAZONIUM COMPOUND; DIETHYLNITROSAMINE; DNA; EPOXIDE; GUANINE; NUCLEOPHILE 4 (4 NITROBENZYL)PYRIDINE; PYRIDINE DERIVATIVE; UNCLASSIFIED DRUG;

EID: 84862528075     PISSN: 0893228X     EISSN: 15205010     Source Type: Journal    
DOI: 10.1021/tx300317d     Document Type: Erratum
Times cited : (23)

References (220)
  • 1
    • 0000785768 scopus 로고
    • Carcinogenesis by Alkylating Agents
    • (Searle, C. E. Ed.) pp, American Chemical Society, Washington, DC
    • Lawley, P. (1976) Carcinogenesis by Alkylating Agents, in Chemical Carcinogens (Searle, C. E., Ed.) pp 83-244, American Chemical Society, Washington, DC.
    • (1976) Chemical Carcinogens , pp. 83-244
    • Lawley, P.1
  • 2
    • 72749086094 scopus 로고    scopus 로고
    • An overview of chemical processes that damage cellular DNA: Spontaneous hydrolysis, alkylation, and reactions with radicals
    • Gates, K. S. (2009) An overview of chemical processes that damage cellular DNA: spontaneous hydrolysis, alkylation, and reactions with radicals Chem. Res. Toxicol. 22, 1747-1760
    • (2009) Chem. Res. Toxicol. , vol.22 , pp. 1747-1760
    • Gates, K.S.1
  • 3
    • 33947479787 scopus 로고
    • Use of g-(4-nitrobenzyl)pyridine as analytical reagent for ethylenimines and alkylating agents
    • Epstein, J., Rosenthal, R. W., and Ess, R. J. (1955) Use of g-(4-nitrobenzyl)pyridine as analytical reagent for ethylenimines and alkylating agents Anal. Chem. 27, 1435-1439
    • (1955) Anal. Chem. , vol.27 , pp. 1435-1439
    • Epstein, J.1    Rosenthal, R.W.2    Ess, R.J.3
  • 4
    • 0026498487 scopus 로고
    • Use of 4-(nitrobenzyl)pyridine (4-NBP) to test mutagenic potential of slow-reacting epoxides, their corresponding olefins, and other alkylating-agents
    • Kim, J. H. and Thomas, J. J. (1992) Use of 4-(nitrobenzyl)pyridine (4-NBP) to test mutagenic potential of slow-reacting epoxides, their corresponding olefins, and other alkylating-agents Bull. Environ. Contam. Toxicol. 49, 879-885
    • (1992) Bull. Environ. Contam. Toxicol. , vol.49 , pp. 879-885
    • Kim, J.H.1    Thomas, J.J.2
  • 16
    • 0001216149 scopus 로고    scopus 로고
    • Covalent Modification of DNA by Natural Products
    • (Kool, E. T. Ed.), Pergamon, New York
    • Gates, K. S. (1999) Covalent Modification of DNA by Natural Products, in Comprehensive Natural Products Chemistry (Kool, E. T., Ed.) pp 491-552, Pergamon, New York.
    • (1999) Comprehensive Natural Products Chemistry , pp. 491-552
    • Gates, K.S.1
  • 17
    • 0036628558 scopus 로고    scopus 로고
    • Mechanisms of in situ activation for DNA-targeting antitumor agents
    • DOI 10.1021/cr010046q
    • Wolkenberg, S. E. and Boger, D. L. (2002) Mechanisms of in situ activation for DNA-targeting antitumor agents Chem. Rev. 102, 2477-2495 (Pubitemid 35377633)
    • (2002) Chemical Reviews , vol.102 , Issue.7 , pp. 2477-2495
    • Wolkenberg, S.E.1    Boger, D.L.2
  • 18
    • 0036519363 scopus 로고    scopus 로고
    • DNA and its associated processes as targets for cancer therapy
    • Hurley, L. H. (2002) DNA and its associated processes as targets for cancer therapy Nat. Rev. Cancer 2, 188-200 (Pubitemid 37328788)
    • (2002) Nature Reviews Cancer , vol.2 , Issue.3 , pp. 188-200
    • Hurley, L.H.1
  • 20
    • 84862516982 scopus 로고
    • Ueber die Beziehungen des doppelt gebundenen Kohlenstoffs zum Stickstoff, Sauerstoff und Schwefel
    • Decker, H. (1905) Ueber die Beziehungen des doppelt gebundenen Kohlenstoffs zum Stickstoff, Sauerstoff und Schwefel Ber. Dtsch. Chem. Ges. 38, 2493-2511
    • (1905) Ber. Dtsch. Chem. Ges. , vol.38 , pp. 2493-2511
    • Decker, H.1
  • 23
    • 0001120151 scopus 로고
    • A study of comparative chemical and biological activities of alkylating agents
    • Bardos, T. J., Datta-Gupta, N., Hebborn, P., and Triggle, D. J. (1965) A study of comparative chemical and biological activities of alkylating agents J. Med. Chem. 8, 167-174
    • (1965) J. Med. Chem. , vol.8 , pp. 167-174
    • Bardos, T.J.1    Datta-Gupta, N.2    Hebborn, P.3    Triggle, D.J.4
  • 24
    • 0025232478 scopus 로고
    • DNA-directed alkylating agents. 1. Structure-activity relationships for acridine-linked aniline mustards: Consequences of varying the reactivity of the mustard
    • Gourdie, T. A., Valu, K. K., Gravatt, G. L., Boritzki, T. J., Baguley, B. C., Wakelin, L. P. G, Wilson, W. R., Woodgate, P. D., and Denny, W. A. (1990) DNA-directed alkylating agents. 1. Structure-activity relationships for acridine-linked aniline mustards: consequences of varying the reactivity of the mustard J. Med. Chem. 33, 1177-1186 (Pubitemid 20115421)
    • (1990) Journal of Medicinal Chemistry , vol.33 , Issue.4 , pp. 1177-1186
    • Gourdie, T.A.1    Valu, K.K.2    Gravatt, G.L.3    Boritzki, T.J.4    Baguley, B.C.5    Wakelin, L.P.G.6    Wilson, W.R.7    Woodgate, P.D.8    Denny, W.A.9
  • 25
    • 0001627927 scopus 로고
    • Synthesis, molecular symmetry, and chemical-reactivity of C-aryl-substituted phosphoraziridines
    • Perlman, M. E. and Bardos, T. J. (1988) Synthesis, molecular symmetry, and chemical-reactivity of C-aryl-substituted phosphoraziridines J. Org. Chem. 53, 1761-1767
    • (1988) J. Org. Chem. , vol.53 , pp. 1761-1767
    • Perlman, M.E.1    Bardos, T.J.2
  • 26
    • 0015577981 scopus 로고
    • Epoxy derivatives of aromatic polycyclic-hydrocarbons: Preparation and metabolism of epoxides related to 7,12-dimethylbenz[alpha]anthracene
    • Sims, P. (1973) Epoxy derivatives of aromatic polycyclic-hydrocarbons: preparation and metabolism of epoxides related to 7,12-dimethylbenz[alpha] anthracene Biochem. J. 131, 405-413
    • (1973) Biochem. J. , vol.131 , pp. 405-413
    • Sims, P.1
  • 27
    • 0015807148 scopus 로고
    • Some properties of "k-region" epoxides of polycyclic aromatic hydrocarbons
    • Swaisland, A. J., Grover, P. L., and Sims, P. (1973) Some properties of "K-region" epoxides of polycyclic aromatic hydrocarbons Biochem. Pharmacol. 22, 1547-1556
    • (1973) Biochem. Pharmacol. , vol.22 , pp. 1547-1556
    • Swaisland, A.J.1    Grover, P.L.2    Sims, P.3
  • 29
    • 0028989071 scopus 로고
    • Application of 15N nuclear magnetic resonance spectroscopy to the determination of the stability of aryl nitrogen mustards
    • Wilman, D. E. V., Palmer, B. D., and Denny, W. A. (1995) Application of 15N nuclear magnetic resonance spectroscopy to the determination of the stability of aryl nitrogen mustards J. Med. Chem. 38, 2256-2258
    • (1995) J. Med. Chem. , vol.38 , pp. 2256-2258
    • Wilman, D.E.V.1    Palmer, B.D.2    Denny, W.A.3
  • 30
    • 0345412531 scopus 로고    scopus 로고
    • Synthesis of a Prodrug Designed to Release Multiple Inhibitors of the Epidermal Growth Factor Receptor Tyrosine Kinase and an Alkylating Agent: A Novel Tumor Targeting Concept
    • DOI 10.1021/jm030423m
    • Banerjee, R., Rachid, Z., McNamee, J., and Jean-Claude, B. J. (2003) Synthesis of a prodrug designed to release multiple inhibitors of the epidermal growth factor receptor tyrosine kinase and an alkylating agent: A novel tumor targeting concept J. Med. Chem. 46, 5546-5551 (Pubitemid 37490384)
    • (2003) Journal of Medicinal Chemistry , vol.46 , Issue.25 , pp. 5546-5551
    • Banerjee, R.1    Rachid, Z.2    McNamee, J.3    Jean-Claude, B.J.4
  • 32
    • 0020595342 scopus 로고
    • 6 : 7-alkylguanine ratio in DNA with carcinogenic potency in rodents
    • Bartsch, H., Terracini, B., Malaveille, C., Tomatis, L., Wahrendorf, J., Brun, G., and Dodet, B. (1983) Quantitative comparison of carcinogenicity, mutagenicity and electrophilicity of 10 direct-acting alkylating agents and of the initial O6: 7-alkylguanine ratio in DNA with carcinogenic potency in rodents Mutat. Res.-Fundam. Mol. Mech. Mutag. 110, 181-219 (Pubitemid 13036839)
    • (1983) Mutation Research , vol.110 , Issue.2 , pp. 181-219
    • Bartsch, H.1    Terracini, B.2    Malaveille, C.3
  • 33
    • 0023690015 scopus 로고
    • A quantitative structure activity relationship for the acute toxicity of some epoxy compounds to the guppy
    • Deneer, J. W., Sinnige, T. L., Seinen, W., and Hermens, J. L. M. (1988) A quantitative structure activity relationship for the acute toxicity of some epoxy compounds to the guppy Aquat. Toxicol. 13, 195-204
    • (1988) Aquat. Toxicol. , vol.13 , pp. 195-204
    • Deneer, J.W.1    Sinnige, T.L.2    Seinen, W.3    Hermens, J.L.M.4
  • 34
    • 0028071579 scopus 로고
    • Reaction kinetics of alkyl epoxides with DNA and other nucleophiles
    • DOI 10.1016/0009-2797(94)90085-X
    • Hemminki, A., Vayrynen, T., and Hemminki, K. (1994) Reaction-kinetics of alkyl epoxides with DNA and other nucleophiles Chem.-Biol. Interact. 93, 51-58 (Pubitemid 24259423)
    • (1994) Chemico-Biological Interactions , vol.93 , Issue.1 , pp. 51-58
    • Hemminki, A.1    Vayrynen, T.2    Hemminki, K.3
  • 35
    • 0019378930 scopus 로고
    • Reactions of β-propiolactone, β-butyrolactone and γ-butyrolactone with nucleic-acids
    • Hemminki, K. (1981) Reactions of β-propiolactone, β-butyrolactone and γ-butyrolactone with nucleic-acids Chem.-Biol. Interact. 34, 323-331
    • (1981) Chem.-Biol. Interact. , vol.34 , pp. 323-331
    • Hemminki, K.1
  • 36
    • 0018405966 scopus 로고
    • Correlation of mutagenicity and 4-(p-nitrobenzyl)-pyridine alkylation by epoxides
    • DOI 10.1016/0378-4274(79)90082-1
    • Hemminki, K. and Falck, K. (1979) Correlation of mutagenicity and 4-(p -nitrobenzyl)-pyridine alkylation by epoxides Toxicol. Lett. 4, 103-106 (Pubitemid 9230859)
    • (1979) Toxicology Letters , vol.4 , Issue.2 , pp. 103-106
    • Hemminki, K.1    Falck, K.2
  • 38
    • 0020078748 scopus 로고
    • Mutagenic and alkylating activities of 3-methyl-1-phenyltriazenes and their possible role as carcinogenic metabolites of the parent dimethyl compounds
    • Malaveille, C., Brun, G., Kolar, G., and Bartsch, H. (1982) Mutagenic and alkylating activities of 3-methyl-1-phenyltriazenes and their possible role as carcinogenic metabolites of the parent dimethyl compounds Cancer Res. 42, 1446-1453 (Pubitemid 12148789)
    • (1982) Cancer Research , vol.42 , Issue.4 , pp. 1446-1453
    • Malaveille, C.1    Brun, G.2    Kolar, G.3    Bartsch, H.4
  • 39
    • 0018091566 scopus 로고
    • Synthesis of diethylstilbestrol metabolites. -Hydroxy-dienestrol and derivatives
    • DOI 10.1016/0040-4020(78)87007-0
    • Metzler, M. (1978) Synthesis of diethylstilbestrol metabolites-omega- hydroxy-dienestrol and derivatives Tetrahedron 34, 3113-3117 (Pubitemid 9035337)
    • (1978) Tetrahedron , vol.34 , Issue.20 , pp. 3113-3117
    • Metzler, M.1
  • 40
    • 0005911131 scopus 로고
    • Comparison of the alkylation of nicotinamide and 4-(p-nitrobenzyl) pyridine for the determination of aliphatic epoxides
    • Nelis, H. J. C. F., Airy, S. C., and Sinsheimer, J. E. (1982) Comparison of the alkylation of nicotinamide and 4-(p-nitrobenzyl)pyridine for the determination of aliphatic epoxides Anal. Chem. 54, 213-216
    • (1982) Anal. Chem. , vol.54 , pp. 213-216
    • Nelis, H.J.C.F.1    Airy, S.C.2    Sinsheimer, J.E.3
  • 41
    • 0022342172 scopus 로고
    • Olefin oxygenation and N-dealkylation by dopamine beta-monooxygenase: Catalysis and mechanism-based inhibition
    • DOI 10.1021/bi00342a021
    • Padgette, S. R., Wimalasena, K., Herman, H. H., Sirimanne, S. R., and May, S. W. (1985) Olefin oxygenation and N-dealkylation by dopamine beta-monooxygenase: catalysis and mechanism-based inhibition Biochemistry 24, 5826-5839 (Pubitemid 16203021)
    • (1985) Biochemistry , vol.24 , Issue.21 , pp. 5826-5839
    • Padgette, S.R.1    Wimalasena, K.2    Herman, H.H.3
  • 42
    • 0018763188 scopus 로고
    • Metabolic and mutagenicity studies on DDT and 15 derivatives. Detection of 1,1-bis(p-chlorophenyl)-2,2-dichloroethane and 1,1-bis(p-chlorophenyl)-2,2,2- trichloroethyl acetate (kelthane acetate) as mutagens in Salmonella typhimurium and of 1,1-bis(p-chlorophenyl) ethylene oxide, a likely metabolite, as an alkylating agent
    • DOI 10.1016/0009-2797(79)90043-7
    • Planche, G., Croisy, A., Malaveille, C., Tomatis, L., and Bartsch, H. (1979) Metabolic and mutagenicity studies on DDT and 15 derivatives. Detection of 1.1-bis(p -chlorophenyl)-2,2-dichloroethane and bis(p -chlorophenyl)-2,2,2- trichloroethyl acetate (kelthane acetate) as mutagens in Salmonella typhimurium and of 1.1-bis(p -chlorophenyl) ethylene oxide, a likely metabolite, as an alkylating agent Chem.-Biol. Interact. 25, 157-175 (Pubitemid 9199353)
    • (1979) Chemico-Biological Interactions , vol.25 , Issue.2-3 , pp. 157-175
    • Planche, G.1    Croisy, A.2    Malaveille, C.3
  • 43
    • 0020003087 scopus 로고
    • 2 in deoxyguanosine by dehydroretronecine, a carcinogenic metabolite of the pyrrolizidine alkaloid monocrotaline
    • Robertson, K. A. (1982) Alkylation of N-2 in deoxyguanosine by dehydroretronecine, a carcinogenic metabolite of the pyrrolizidine alkaloid monocrotaline Cancer Res. 42, 8-14 (Pubitemid 12207238)
    • (1982) Cancer Research , vol.42 , Issue.1 , pp. 8-14
    • Robertson, K.A.1
  • 44
    • 0022443238 scopus 로고
    • Mutagenicity of para-substituted alpha-methylstyrene oxide derivatives with Salmonella
    • Rosman, L. B., Beylin, V. G., Gaddamidi, V., Hooberman, B. H., and Sinsheimer, J. E. (1986) Mutagenicity of para -substituted α-methylstyrene oxide derivatives with Salmonella Mutat. Res. 171, 63-70 (Pubitemid 16051624)
    • (1986) Mutation Research , vol.171 , Issue.2-3 , pp. 63-70
    • Rosman, L.B.1    Beylin, V.G.2    Gaddamidi, V.3
  • 45
    • 0024446913 scopus 로고
    • Mutagenicity of oxaspiro compounds with Salmonella
    • Sinsheimer, J. E., Chakraborty, P. K., Messerly, E. A., and Gaddamidi, V. (1989) Mutagenicity of oxaspiro compounds with Salmonella Mutat. Res.-Genet. Toxicol. Environ. Mutag. 224, 171-175 (Pubitemid 19248948)
    • (1989) Mutation Research , vol.224 , Issue.2 , pp. 171-175
    • Sinsheimer, J.E.1    Chakraborty, P.K.2    Messerly, E.A.3    Gaddamidi, V.4
  • 46
    • 0028930987 scopus 로고
    • Enhancement of bacterial mutagenicity of bifunctional alkylating agents by expression of mammalian glutathione S-transferase
    • Thier, R., Muller, M., Taylor, J. B., Pemble, S. E., Ketterer, B., and Guengerich, F. P. (1995) Enhancement of bacterial mutagenicity of bifunctional alkylating agents by expression of mammalian glutathione S-transferase Chem. Res. Toxicol. 8, 465-472
    • (1995) Chem. Res. Toxicol. , vol.8 , pp. 465-472
    • Thier, R.1    Muller, M.2    Taylor, J.B.3    Pemble, S.E.4    Ketterer, B.5    Guengerich, F.P.6
  • 48
    • 0019465770 scopus 로고
    • Alkylating properties and genetic activity of 4-vinylcyclohexene metabolites and structurally related epoxides
    • Turchi, G., Bonatti, S., Citti, L., Gervasi, P. G., Abbondandolo, A., and Presciuttini, S. (1981) Alkylating properties and genetic-activity of 4-vinylcyclohexene metabolites and structurally related epoxides Mutat. Res. 83, 419-430 (Pubitemid 11060938)
    • (1981) Mutation Research , vol.83 , Issue.3 , pp. 419-430
    • Turchi, G.1    Bonatti, S.2    Citti, L.3
  • 49
    • 12344302575 scopus 로고
    • Five new methods for the spectrophotometric determination of alkylating agents including some extremely sensitive autocatalytic methods. Application to air pollution
    • Sawicki, E., Bender, D. F., Houser, T. R., Wilson, R. M., and Meeker, J. E. (1963) Five new methods for the spectrophotometric determination of alkylating agents including some extremely sensitive autocatalytic methods. Application to air pollution Anal. Chem. 35, 1479-1486
    • (1963) Anal. Chem. , vol.35 , pp. 1479-1486
    • Sawicki, E.1    Bender, D.F.2    Houser, T.R.3    Wilson, R.M.4    Meeker, J.E.5
  • 50
    • 49749202433 scopus 로고
    • The effect of glucose pretreatment on the anti-tumour action of Mannitol Myleran
    • Connors, T. A., Elson, L. A., and Leese, C. L. (1964) The effect of glucose pretreatment on the anti-tumour action of Mannitol Myleran Biochem. Pharmacol. 13, 963-968
    • (1964) Biochem. Pharmacol. , vol.13 , pp. 963-968
    • Connors, T.A.1    Elson, L.A.2    Leese, C.L.3
  • 51
    • 0018861257 scopus 로고
    • Mutagenic potential of allyl and allylic compounds. Structure-activity relationship as determined by alkylating and direct in vitro mutagenic properties
    • DOI 10.1016/0006-2952(80)90161-6
    • Eder, E., Neudecker, T., Lutz, D., and Henschler, D. (1980) Mutagenic potential of allyl and allylic compounds: Structure-activity relationship as determined by alkylating and direct in vitro mutagenic properties Biochem. Pharmacol. 29, 993-998 (Pubitemid 10129871)
    • (1980) Biochemical Pharmacology , vol.29 , Issue.7 , pp. 993-998
    • Eder, E.1    Neudecker, T.2    Lutz, D.3    Henschler, D.4
  • 52
    • 0018822559 scopus 로고
    • Structure-activity relationship in halogen and alkyl substituted allyl and allylic compounds: Correlation of alkylating and mutagenic properties
    • DOI 10.1016/0006-2952(80)90075-1
    • Neudecker, T., Lutz, D., Eder, E., and Henschler, D. (1980) Structure-activity relationship in halogen and alkyl substituted allyl and allylic compounds: Correlation of alkylating and mutagenic properties Biochem. Pharmacol. 29, 2611-2617 (Pubitemid 10060018)
    • (1980) Biochemical Pharmacology , vol.29 , Issue.19 , pp. 2611-2617
    • Neudecker, T.1    Lutz, D.2    Eder, E.3    Henschler, D.4
  • 53
    • 0019431920 scopus 로고
    • In vivo investigation of some metabolic changes of 3-[bis-(2-chloroethyl) -carbohydrazide]-2,2,5,5-tetramethylpyroline-1-oxyl by the NBP-reaction and ESR method
    • DOI 10.1016/0006-2952(81)90056-3
    • Raïkova, E., Grueva, D., and Golovinsky, E. (1981) In vivo investigation of some metabolic changes of 3-[bis-(2-chlorethyl)-carbohydrazide] -2,2,5,5-tetramethylpyroline-1-oxyl by the NBP-reaction and ESR method Biochem. Pharmacol. 30, 289-291 (Pubitemid 11142605)
    • (1981) Biochemical Pharmacology , vol.30 , Issue.4 , pp. 289-291
    • Raikova, E.1    Grueva, D.2    Golovinsky, E.3
  • 54
    • 0020057065 scopus 로고
    • Correlation of alkylating and mutagenic activities of allyl and allylic compounds: Standard alkylation test vs. kinetic investigation
    • DOI 10.1016/0009-2797(82)90060-6
    • Eder, E., Neudecker, T., Lutz, D., and Henschler, D. (1982) Correlation of akylating and mtagenic activities of allyl and allylic compounds: Standard alkylation test vs kinetic investigation Chem.-Biol. Interact. 38, 303-315 (Pubitemid 12171344)
    • (1982) Chemico-Biological Interactions , vol.38 , Issue.3 , pp. 303-315
    • Eder, E.1    Neudecker, T.2    Lutz, D.3    Henschler, D.4
  • 55
    • 0021255529 scopus 로고
    • Lack of mutagenicity to S. typhimurium of neopentyl bromide and pentaerythrityl tetrachloride: Relation to chemical structure
    • Ashby, J., Callander, R. D., and Gilman, D. (1984) Lack of mutagenicity to S. typhimurium of neopentyl bromide and pentaerythrityl tetrachloride: relation to chemical structure Mutat. Res. Lett. 140, 71-74 (Pubitemid 14084876)
    • (1984) Mutation Research , vol.140 , Issue.2-3 , pp. 71-74
    • Ashby, J.1    Callander, R.D.2    Gilman, D.3
  • 56
    • 0021069138 scopus 로고
    • Rat liver microsomal transformation of ethene to oxirane in vitro
    • Schmiedel, G., Filser, J. G., and Bolt, H. M. (1983) Rat liver microsomal transformation of ethene to oxirane in vitro Toxicol. Lett. 19, 293-297 (Pubitemid 14208529)
    • (1983) Toxicology Letters , vol.19 , Issue.3 , pp. 293-297
    • Schmiedel, G.1    Filser, J.G.2    Bolt, H.M.3
  • 57
    • 0023221593 scopus 로고
    • 1,2-dibromo compounds. Their mutagenicity in Salmonella strains differing in glutathione content and their alkylating potential
    • DOI 10.1016/0006-2952(87)90246-2
    • Zoetemelk, C. E. M., Mohn, G. R., Vandergen, A., and Breimer, D. D. (1987) 1,2-Dibromo compounds: Their mutagenicity in Salmonella strains differing in glutathione content and their alkylating potential Biochem. Pharmacol. 36, 1829-1835 (Pubitemid 17084466)
    • (1987) Biochemical Pharmacology , vol.36 , Issue.11 , pp. 1829-1835
    • Zoetemelk, C.E.M.1    Mohn, G.R.2    Van Der Gen, A.3    Breimer, D.D.4
  • 58
    • 0015368917 scopus 로고
    • Modification of the alkylating ability of cyclophosphamide by fresh plasma
    • Hill, B. T. and Harrap, K. R. (1972) Modification of the alkylating ability of cyclophosphamide by fresh plasma Chem.-Biol. Interact. 5, 117-125
    • (1972) Chem.-Biol. Interact. , vol.5 , pp. 117-125
    • Hill, B.T.1    Harrap, K.R.2
  • 59
    • 0037384478 scopus 로고    scopus 로고
    • Alkylating reactivity and herbicidal activity of chloroacetamides
    • DOI 10.1002/ps.634
    • Jablonkai, I. (2003) Alkylating reactivity and herbicidal activity of chloroacetamides Pest Manage. Sci. 59, 443-450 (Pubitemid 36402286)
    • (2003) Pest Management Science , vol.59 , Issue.4 , pp. 443-450
    • Jablonkai, I.1
  • 60
    • 0018719155 scopus 로고
    • Pharmacokinetics of cyclophosphamide and alkylating activity in man after intravenous and oral administration
    • Juma, F. D., Rogers, H. J., and Trounce, J. R. (1979) Pharmacokinetics of cyclophosphamide and alkylating activity in man after intravenous and oral-administration Br. J. Clin. Pharmacol. 8, 209-217 (Pubitemid 10226248)
    • (1979) British Journal of Clinical Pharmacology , vol.8 , Issue.3 , pp. 209-217
    • Juma, F.D.1    Rogers, H.J.2    Trounce, J.R.3
  • 61
    • 0018950814 scopus 로고
    • The pharmacokinetics of cyclophosphamide, phosphoramide mustard and nor-nitrogen mustard studied by gas chromatography in patients receiving cyclophosphamide therapy
    • Juma, F. D., Rogers, H. J., and Trounce, J. R. (1980) The pharmacokinetics of cyclophosphamide, phosphoramide mustard and nor-nitrogen mustard studied by gas-chromatography in patients receiving cyclophosphamide therapy Br. J. Clin. Pharmacol. 10, 327-335 (Pubitemid 10004471)
    • (1980) British Journal of Clinical Pharmacology , vol.10 , Issue.4 , pp. 327-335
    • Juma, F.D.1    Rogers, H.J.2    Trounce, J.R.3
  • 64
    • 0019463663 scopus 로고
    • On interactions of cytostatic benzylidine hydrazines with SH-groups
    • DOI 10.1016/0009-2797(81)90146-0
    • Braun, R., Dittmar, W., Hefter, B., and Weber, K. (1981) On interactions of cytostatic benzylidine hydrazines with SH-groups Chem.-Biol. Interact. 35, 229-239 (Pubitemid 11096275)
    • (1981) Chemico-Biological Interactions , vol.35 , Issue.2 , pp. 229-239
    • Braun, R.1    Dittmar, W.2    Hefter, E.3    Weber, K.4
  • 66
    • 0035705912 scopus 로고    scopus 로고
    • Synthesis, antimicrobial, and alkylating properties of 3-phosphonic derivatives of chromone
    • DOI 10.1002/1521-4184(200112)334:12<381::AID-ARDP381>3.0.CO;2-0
    • Budzisz, E., Nawrot, E., and Malecka, M. (2001) Synthesis, antimicrobial, and alkylating properties of 3-phosphonic derivatives of chromone Arch. Pharm. 334, 381-387 (Pubitemid 34118730)
    • (2001) Archiv der Pharmazie , vol.334 , Issue.12 , pp. 381-387
    • Budzisz, E.1    Nawrot, E.2    Malecka, M.3
  • 67
    • 0022005652 scopus 로고
    • Mutagenic and alkylating activities of organophosphate impurities of commercial malathion
    • Imamura, T. and Talcott, R. E. (1985) Mutagenic and alkylating activities of organophosphate impurities of commercial malathion Mutat. Res.-Genet. Toxicol. Environ. Mutag. 155, 1-6 (Pubitemid 15170961)
    • (1985) Mutation Research , vol.155 , Issue.1-2 , pp. 1-6
    • Imamura, T.1    Talcott, R.E.2
  • 68
    • 60149102595 scopus 로고    scopus 로고
    • Cytotoxic activity and chemical reactivity of cis-platinum(II) and trans-palladium(II) complexes with diethyl (pyridinylmethyl)phosphates
    • Kalinowska-Lis, U., Szmigiero, L., Studzian, K., and Ochocki, J. (2009) Cytotoxic activity and chemical reactivity of cis-platinum(II) and trans-palladium(II) complexes with diethyl (pyridinylmethyl)phosphates Eur. J. Med. Chem. 44, 660-664
    • (2009) Eur. J. Med. Chem. , vol.44 , pp. 660-664
    • Kalinowska-Lis, U.1    Szmigiero, L.2    Studzian, K.3    Ochocki, J.4
  • 69
    • 0019482615 scopus 로고
    • Chemically reactive estrogens: Synthesis and estrogen receptor interactions of hexestrol ether derivatives and 4-substituted deoxyhexestrol derivatives bearing alkylating functions
    • DOI 10.1021/jm00136a013
    • Katzenellenbogen, J. A., McGorrin, R. J., Tatee, T., Kempton, R. J., Carlson, K. E., and Kinder, D. H. (1981) Chemically reactive estrogens: synthesis and estrogen receptor interactions of hexestrol ether derivatives and 4-substituted deoxyhexestrol derivatives bearing alkylating functions J. Med. Chem. 24, 435-450 (Pubitemid 11151649)
    • (1981) Journal of Medicinal Chemistry , vol.24 , Issue.4 , pp. 435-450
    • Katzenellenbogen, J.A.1    McGorrin, R.J.2    Tatee, T.3
  • 70
    • 33750594445 scopus 로고    scopus 로고
    • In vivo antitumor, in vitro antibacterial activity and alkylating properties of phosphorohydrazine derivatives of coumarin and chromone
    • DOI 10.1016/j.ejmech.2006.06.004, PII S0223523406002285
    • Nawrot-Modranka, J., Nawrot, E., and Graczyk, J. (2006) In vivo antitumor, in vitro antibacterial activity and alkylating properties of phosphorohydrazine derivatives of coumarin and chromone Eur. J. Med. Chem. 41, 1301-1309 (Pubitemid 44679719)
    • (2006) European Journal of Medicinal Chemistry , vol.41 , Issue.11 , pp. 1301-1309
    • Nawrot-Modranka, J.1    Nawrot, E.2    Graczyk, J.3
  • 72
    • 0014102286 scopus 로고
    • Alterations of some macromolecular and biochemical properties of calf thymus DNA caused by dual antagonists and nitrogen mustard
    • Chmielewicz, Z. F., Fiel, R. J., Bardos, T. J., and Ambrus, J. L. (1967) Alterations of some macromolecular and biochemical properties of calf thymus DNA caused by dual antagonists and nitrogen mustard Cancer Res. 27, 1248-1257
    • (1967) Cancer Res. , vol.27 , pp. 1248-1257
    • Chmielewicz, Z.F.1    Fiel, R.J.2    Bardos, T.J.3    Ambrus, J.L.4
  • 73
    • 33947480040 scopus 로고
    • Colorimetric estimation of nitrogen mustards in aqueous media. Hydrolytic behavior of bis-(β-chloroethyl)amine, nor HN2
    • Friedman, O. M. and Boger, E. (1961) Colorimetric estimation of nitrogen mustards in aqueous media. Hydrolytic behavior of bis-(β-chloroethyl)amine, nor HN2 Anal. Chem. 33, 906-910
    • (1961) Anal. Chem. , vol.33 , pp. 906-910
    • Friedman, O.M.1    Boger, E.2
  • 74
    • 50549171256 scopus 로고
    • Dosage des agents alcoylants dans les milieux biologiques Méthode utilisant la réaction colorée avec la γ-(nitro-4-benzyl)- pyridine en milieu alcalin
    • Truhaut, R., Delacoux, E., Brule, G., and Bohuon, C. (1963) Dosage des agents alcoylants dans les milieux biologiques Méthode utilisant la réaction colorée avec la γ-(nitro-4-benzyl)-pyridine en milieu alcalin Clin. Chim. Acta 8, 235-245
    • (1963) Clin. Chim. Acta , vol.8 , pp. 235-245
    • Truhaut, R.1    Delacoux, E.2    Brule, G.3    Bohuon, C.4
  • 75
    • 0019847596 scopus 로고
    • Alkylating angiotensin II analogues: Synthesis, analysis, and biological activity of angiotensin II analogues containing the nitrogen mustard melphalan in position 8
    • Hsieh, K. H. and Marshall, G. R. (1981) Alkylating angiotensin-II analogs: synthesis, analysis, and biological-activity of angiotensin II analogs containing the nitrogen-mustard melphalan in position-8 J. Med. Chem. 24, 1304-1310 (Pubitemid 12209060)
    • (1981) Journal of Medicinal Chemistry , vol.24 , Issue.11 , pp. 1304-1310
    • Hsieh, K.1    Marshall, G.R.2
  • 76
    • 0019809921 scopus 로고
    • Metabolic activation and cytotoxicity of cyclophosphamide in primary cultures of postnatal rat hepatocytes
    • DOI 10.1016/0006-2952(81)90522-0
    • Acosta, D. and Mitchell, D. B. (1981) Metabolic-activation and cyto-toxicity of cyclophosphamide in primary cultures of postnatal rat hepatocytes Biochem. Pharmacol. 30, 3225-3230 (Pubitemid 12193746)
    • (1981) Biochemical Pharmacology , vol.30 , Issue.23 , pp. 3225-3230
    • Acosta, D.1    Mitchell, D.B.2
  • 77
    • 0019438649 scopus 로고
    • Quantitative-determination of carcinogens and mutagens as alkylating-agents following chemical activation
    • Archer, M. C. and Eng, V. W. S. (1981) Quantitative-determination of carcinogens and mutagens as alkylating-agents following chemical activation Chem.-Biol. Interact. 33, 207-214
    • (1981) Chem.-Biol. Interact. , vol.33 , pp. 207-214
    • Archer, M.C.1    Eng, V.W.S.2
  • 78
    • 0028609968 scopus 로고
    • Clinical pharmacokinetics of cyclophosphamide and metabolites with and without SR-2508
    • Chan, K. K., Hong, P. S., Tutsch, K., and Trump, D. L. (1994) Clinical pharmacokinetics of cyclophosphamide and metabolites with and without SR-2508 Cancer Res. 54, 6421-6429
    • (1994) Cancer Res. , vol.54 , pp. 6421-6429
    • Chan, K.K.1    Hong, P.S.2    Tutsch, K.3    Trump, D.L.4
  • 79
    • 0026767519 scopus 로고
    • Reductive metabolism of diaziquone (AZQ) in the S9 fraction of MCF-7 cells: II. Enhancement of the alkylating activity of AZQ by NAD(P)H: Quinone-acceptor oxidoreductase (DT-diaphorase)
    • Fisher, G. R., Donis, J., and Gutiérrez, P. L. (1992) Reductive metabolism of diaziquone (AZQ) in the S9 fraction of MCF-7 cells: II. Enhancement of the alkylating activity of AZQ by NAD(P)H: quinone-acceptor oxidoreductase (DT-diaphorase) Biochem. Pharmacol. 44, 1625-1635
    • (1992) Biochem. Pharmacol. , vol.44 , pp. 1625-1635
    • Fisher, G.R.1    Donis, J.2    Gutiérrez, P.L.3
  • 80
    • 0019442713 scopus 로고
    • Role of aldehyde dehydrogenase in the metabolism-dependent biological activity of cyclophosphamide
    • Hipkens, J. H., Struck, R. F., and Gurtoo, H. L. (1981) Role of aldehyde dehydrogenase in the metabolism-dependent biological activity of cyclophosphamide Cancer Res. 41, 3571-3583 (Pubitemid 11063640)
    • (1981) Cancer Research , vol.41 , Issue.9 , pp. 3571-3583
    • Hipkens, J.H.1    Struck, R.F.2    Gurtoo, H.L.3
  • 81
    • 0017681673 scopus 로고
    • Alkylation of (4 nitrobenzyl)pyridine by four N diazoacetyl derivatives of amino acids. Lack of fine correlation with the unscheduled DNA synthesis induced in mouse cells 'in vitro'
    • DOI 10.1016/S0031-6989(77)80092-1
    • Parodi, S., Picca, M., Bolognesi, C., Cavanna, M., Carlo, P., Finollo, R., and Brambilla, G. (1977) Alkylation of [gamma]-(4-nitrobenzyl)pyridine by four N-diazoacetyl derivatives of amino acids. Lack of fine correlation with the unscheduled DNA synthesis induced in mouse cells "in vitro" Pharmacol. Res. Commun. 9, 621-631 (Pubitemid 8154965)
    • (1977) Pharmacological Research Communications , vol.9 , Issue.7 , pp. 621-631
    • Parodi, S.1    Picca, M.2    Bolognesi, C.3
  • 82
    • 31344473418 scopus 로고    scopus 로고
    • Evaluation of fluorenhymustine as a rationally designed novel anticancer agent
    • Samanta, S., Pain, A., Ghosh, M., Dutta, S., and Sanyal, U. (2005) Evaluation of fluorenhymustine as a rationally designed novel anticancer agent Exp. Oncol. 27, 279-285 (Pubitemid 43139358)
    • (2005) Experimental Oncology , vol.27 , Issue.4 , pp. 279-285
    • Samanta, S.1    Pain, A.2    Ghosh, M.3    Dutta, S.4    Sanyal, U.5
  • 83
    • 0021037669 scopus 로고
    • The hydrolysis and alkylation activities of S-(2-haloethyl)-L-cysteine analogs - evidence for extended half-life
    • Schasteen, C. S. and Reed, D. J. (1983) The hydrolysis and alkylation activities of S-(2-haloethyl)-L-cysteine analogs: evidence for extended half-life Toxicol. Appl. Pharmacol. 70, 423-432 (Pubitemid 14226981)
    • (1983) Toxicology and Applied Pharmacology , vol.70 , Issue.3 , pp. 423-432
    • Schasteen, C.S.1    Reed, D.J.2
  • 84
    • 0021932117 scopus 로고
    • Mutagenic and chemotherapeutic activity in L1210 leukemia of several monofunctional alkylating agents
    • Schmid, F. A., Otter, G. M., and Mehta, B. M. (1985) Mutagenic and chemotherapeutic activity in L1210 leukemia of several monofunctional alkylating-agents Cancer Res. 45, 40-44 (Pubitemid 15196927)
    • (1985) Cancer Research , vol.45 , Issue.1 , pp. 40-44
    • Schmid, F.A.1    Otter, G.M.2    Mehta, B.M.3
  • 85
    • 0022466393 scopus 로고
    • 1,2-Bis(arylsulfonyl)hydrazines. 2. The influence of arylsulfonyl and aralkylsulfonyl substituents on antitumor and alkylating activity
    • Shyam, K., Cosby, L. A., and Sartorelli, A. C. (1986) 1,2-Bis(arylsulfonyl)hydrazines. 2. The influence of arenesulfonyl and aralkylsulfonyl substituents on antitumor and alkylating activity J. Med. Chem. 29, 1323-1325 (Pubitemid 16059076)
    • (1986) Journal of Medicinal Chemistry , vol.29 , Issue.7 , pp. 1323-1325
    • Shyam, K.1    Furubayashi, R.2    Hrubiec, R.T.3
  • 87
    • 0014062292 scopus 로고
    • Alkylating activity of 1,3-bis(2-chloroethyl)-1-nitrosourea and related compounds
    • Wheeler, G. P. and Chumley, S. (1967) Alkylating activity of 1,3-bis(2-chloroethyl)-1-nitrosourea and related compounds J. Med. Chem. 10, 259-261
    • (1967) J. Med. Chem. , vol.10 , pp. 259-261
    • Wheeler, G.P.1    Chumley, S.2
  • 88
    • 0022640856 scopus 로고
    • Circumvention of deficient activation in mitomycin C-resistant human colonic carcinoma cells by the mitomycin C analogue BMY25282
    • Chakrabarty, S., Danels, Y. J., Long, B. H., Willson, J. K. V., and Brattain, M. G. (1986) Circumvention of deficient activation in mitomycin C-resistant human colonic-carcinoma cells by the mitomycin-C analog Bmy25282 Cancer Res. 46, 3456-3458 (Pubitemid 16096890)
    • (1986) Cancer Research , vol.46 , Issue.7 , pp. 3456-3458
    • Chakrabarty, S.1    Danels, Y.J.2    Long, B.H.3
  • 89
    • 0022408368 scopus 로고
    • Effects of glutathione and ethylxanthate on mitomycin C activation by isolated rat hepatic or EMT6 mouse mammary tumor nuclei
    • Kennedy, K. A., Mimnaugh, E. G., Trush, M. A., and Sinha, B. K. (1985) Effects of glutathione and ethylxanthate on mitomycin-C activation by isolated rat hepatic or EMT6 mouse mammary-tumor nuclei Cancer Res. 45, 4071-4076 (Pubitemid 16224852)
    • (1985) Cancer Research , vol.45 , Issue.9 , pp. 4071-4076
    • Kennedy, K.A.1    Mimnaugh, E.G.2    Trush, M.A.3    Sinha, B.K.4
  • 90
  • 91
    • 0026032132 scopus 로고
    • Studies on the mechanism of resistance to mitomycin-C and porfiromycin in a human cell strain derived from a cancer-prone individual
    • Marshall, R. S., Paterson, M. C., and Rauth, A. M. (1991) Studies on the mechanism of resistance to mitomycin-C and porfiromycin in a human cell strain derived from a cancer-prone individual Biochem. Pharmacol. 41, 1351-1360
    • (1991) Biochem. Pharmacol. , vol.41 , pp. 1351-1360
    • Marshall, R.S.1    Paterson, M.C.2    Rauth, A.M.3
  • 92
    • 0026662198 scopus 로고
    • Uroepithelial and nephrotubula toxicity in patients receiving ifosfamide/mesna: Measurement of urinary N -acetyl-β-D-glucosaminidase and β-2-microglobulin
    • Lewis, L. D., Burton, L. C., Harper, P. G., and Rogers, H. J. (1992) Uroepithelial and nephrotubula toxicity in patients receiving ifosfamide/mesna: Measurement of urinary N -acetyl-β-D-glucosaminidase and β-2-microglobulin Eur. J. Cancer 28, 1976-1981
    • (1992) Eur. J. Cancer , vol.28 , pp. 1976-1981
    • Lewis, L.D.1    Burton, L.C.2    Harper, P.G.3    Rogers, H.J.4
  • 93
    • 0025123984 scopus 로고
    • Fractionated ifosfamide therapy produces a time-dependent increase in ifosfamide metabolism
    • Lewis, L. D., Fitzgerald, D. L., Harper, P. G., and Rogers, H. J. (1990) Fractionated ifosfamide therapy produces a time-dependent increase in ifosfamide metabolism Br. J. Clin. Pharmacol. 30, 725-732 (Pubitemid 20377602)
    • (1990) British Journal of Clinical Pharmacology , vol.30 , Issue.5 , pp. 725-732
    • Lewis, L.D.1    Fitzgerald, D.L.2    Harper, P.G.3    Rogers, H.J.4
  • 95
    • 0345020361 scopus 로고    scopus 로고
    • Comparative pharmacokinetics of oral and intravenous ifosfamide/mesna/ methylene blue therapy
    • Aeschlimann, C., Kupfer, A., Schefer, H., and Cerny, T. (1998) Comparative pharmacokinetics of oral and intravenous ifosfamide/mesna methylene blue therapy Drug Metab. Dispos. 26, 883-890 (Pubitemid 28452055)
    • (1998) Drug Metabolism and Disposition , vol.26 , Issue.9 , pp. 883-890
    • Aeschlimann, C.1    Kupfer, A.2    Schefer, H.3    Cerny, T.4
  • 97
    • 0018975132 scopus 로고
    • Modification of the 4-(p-nitrobenzyl) pyridine assay for measurement of melphalan and mechlorethamine in plasma
    • DOI 10.1016/0160-5402(80)90034-0
    • Skibba, J. L. and Collins, F. G. (1980) Modification of the 4-(para-nitrobenzyl) pyridine assay for measurement of melphalan and mechlorethamine in plasma J. Pharmacol. Methods 4, 155-163 (Pubitemid 10046778)
    • (1980) Journal of Pharmacological Methods , vol.4 , Issue.2 , pp. 155-163
    • Skibba, J.L.1    Collins, F.G.2
  • 98
    • 0023236184 scopus 로고
    • Linear free energy relationships and cytotoxicities of para-substituted 2-haloethyl aryl selenides and bis(2-chloroethyl) selenides
    • DOI 10.1021/jm00387a003
    • Kang, S. I. and Spears, C. P. (1987) Linear free energy relationships and cytotoxicities of para-substituted 2-haloethyl aryl selenides and bis(2-chloroethyl) selenides J. Med. Chem. 30, 597-602 (Pubitemid 17065190)
    • (1987) Journal of Medicinal Chemistry , vol.30 , Issue.4 , pp. 597-602
    • Kang, S.-I.1    Spears, C.P.2
  • 100
    • 0021268884 scopus 로고
    • Studies on chemical carcinogens and mutagens. XXV. Chemoselectivity of alkyl sulfonates toward 4-(p-nitrobenzyl)pyridine (NBP) in phosphate buffer
    • Ninomiya, S., Kohda, K., and Kawazoe, Y. (1984) Studies on chemical carcinogens and mutagens. XXV. Chemoselectivity of alkyl sulfonates toward 4-(p -Nitrobenzyl)-pyridine (NBP) in phosphate buffer Chem. Pharm. Bull. 32, 1326-1332 (Pubitemid 14101049)
    • (1984) Chemical and Pharmaceutical Bulletin , vol.32 , Issue.4 , pp. 1326-1332
    • Ninomiya, S.I.1    Kohda, K.2    Kawazoe, Y.3
  • 101
    • 0020469456 scopus 로고
    • Studies on chemical carcinogens. XXIII. A simple method for characterization of the alkylating ability of compounds by using 4-(p-Nitrobenzyl)pyridine
    • Kawazoe, Y., Tamura, N., and Yoshimura, T. (1982) Studies on chemical carcinogens. XXIII. A simple method for characterization of the alkylating ability of compounds by using 4-(p -Nitrobenzyl)-pyridine Chem. Pharm. Bull. 30, 2077-2086 (Pubitemid 13231883)
    • (1982) Chemical and Pharmaceutical Bulletin , vol.30 , Issue.6 , pp. 2077-2086
    • Kawazoe, Y.1    Tamura, N.2    Yoshimura, T.3
  • 102
    • 0021792249 scopus 로고
    • Evidence for the mode of antischistosomal action of hycanthone
    • Cioli, D., Picamattoccia, L., Rosenberg, S., and Archer, S. (1985) Evidence for the mode of antischistosomal action of hycanthone Life Sci. 37, 161-167 (Pubitemid 15060121)
    • (1985) Life Sciences , vol.37 , Issue.2 , pp. 161-167
    • Cioli, D.1    Pica-Mattoccia, L.2    Rosenberg, S.3    Archer, S.4
  • 103
    • 0021181405 scopus 로고
    • Effects of pH and temperature on the stability and decomposition of N,N'N''-triethylenethiophosphoramide in urine and buffer
    • Cohen, B. E., Egorin, M. J., Nayar, M. S. B., and Gutiérrez, P. L. (1984) Effects of pH and temperature on the stability and decomposition of N,N′N″-triethylenethiophosphoramide in urine and buffer Cancer Res. 44, 4312-4316 (Pubitemid 14008741)
    • (1984) Cancer Research , vol.44 , Issue.10 , pp. 4312-4316
    • Cohen, B.E.1    Egorin, M.J.2    Nayar, M.S.B.3    Gutierrez, P.L.4
  • 104
    • 0025350560 scopus 로고
    • 14C]thiotepa: Labeling of phosphatidylethanolamine
    • Egorin, M. J. and Snyder, S. W. (1990) Characterization of non-exchangeable radioactivity in L1210 cells incubated with [C-14] Thiotepa-Labeling of phosphatidylethanolamine Cancer Res. 50, 4044-4049 (Pubitemid 20225628)
    • (1990) Cancer Research , vol.50 , Issue.13 , pp. 4044-4049
    • Egorin, M.J.1    Snyder, S.W.2
  • 105
    • 0024467068 scopus 로고
    • Cellular transport and accumulation of thiotepa in murine, human, and avian cells
    • Egorin, M. J., Snyder, S. W., Pan, S.-s., and Daly, C. (1989) Cellular transport and accumulation of thiotepa in murine, human, and avian cells Cancer Res. 49, 5611-5617 (Pubitemid 19256440)
    • (1989) Cancer Research , vol.49 , Issue.20 , pp. 5611-5617
    • Egorin, M.J.1    Snyder, S.W.2    Pan, S.3    Daly, C.4
  • 106
    • 0017723984 scopus 로고
    • Synthesis and biological action of two glucocorticoid alkylating agents
    • DOI 10.1021/jm00219a005
    • El Masry, A. H., Braun, V. C., Nielsen, C. J., and Pratt, W. B. (1977) Synthesis and biological action of two gluco corticoid alkylating agents J. Med. Chem. 20, 1134-1139 (Pubitemid 8170470)
    • (1977) Journal of Medicinal Chemistry , vol.20 , Issue.9 , pp. 1134-1139
    • El Masry, A.H.1    Braun, V.C.2    Nielsen, C.J.3    Pratt, W.B.4
  • 107
    • 0019451593 scopus 로고
    • Macrocyclic trichothecene toxins produced by a strain of Stachybotrys atra from Hungary
    • Harrach, B., Mirocha, C. J., Pathre, S. V., and Palyusik, M. (1981) Macrocyclic trichothecene toxins produced by a strain of Stachybotrys-Atra from Hungary Appl. Environ. Microbiol. 41, 1428-1432 (Pubitemid 11041083)
    • (1981) Applied and Environmental Microbiology , vol.41 , Issue.6 , pp. 1428-1432
    • Harrach, B.1    Mirocha, C.J.2    Pathre, S.V.3    Palyusik, M.4
  • 108
    • 0033579601 scopus 로고    scopus 로고
    • Monitoring the solid-phase synthesis of depsides and depsipeptides. A color test for hydroxyl groups linked to a resin
    • Kuisle, O., Lolo, M., Quiñoá, E., and Riguera, R. (1999) Monitoring the solid-phase synthesis of depsides and depsipeptides. A color test for hydroxyl groups linked to a resin Tetrahedron 55, 14807-14812
    • (1999) Tetrahedron , vol.55 , pp. 14807-14812
    • Kuisle, O.1    Lolo, M.2    Quiñoá, E.3    Riguera, R.4
  • 110
    • 0015607955 scopus 로고
    • Evidence for an aldehyde possessing alkylating activity as primary metabolite of cyclophosphamide
    • Sladek, N. E. (1973) Evidence for an aldehyde possessing alkylating activity as primary metabolite of cyclophosphamide Cancer Res. 33, 651-658
    • (1973) Cancer Res. , vol.33 , pp. 651-658
    • Sladek, N.E.1
  • 111
    • 0023262622 scopus 로고
    • Plasma pharmacokinetics of cyclophosphamide and its cytotoxic metabolites after intravenous versus oral administration in a randomized, crossover trial
    • Struck, R. F., Alberts, D. S., Horne, K., Phillips, J. G., Peng, Y.-M., and Roe, D. J. (1987) Plasma pharmacokinetics of cyclophosphamide and its cytotoxic metabolites after intravenous versus oral administration in a randomized, crossover trial Cancer Res. 47, 2723-2726 (Pubitemid 17083165)
    • (1987) Cancer Research , vol.47 , Issue.10 , pp. 2723-2726
    • Struck, R.F.1    Alberts, D.S.2    Horne, K.3
  • 112
    • 0018797652 scopus 로고
    • Spectrodensitometric determination of trichothecene mycotoxins with 4-(p -nitrobenzyl)pyridine on silica-gel thin-layer chromatograms
    • Takitani, S., Asabe, Y., Kato, T., Suzuki, M., and Ueno, Y. (1979) Spectrodensitometric determination of trichothecene mycotoxins with 4-(p -nitrobenzyl)pyridine on silica-gel thin-layer chromatograms J. Chromatogr. 172, 335-342
    • (1979) J. Chromatogr. , vol.172 , pp. 335-342
    • Takitani, S.1    Asabe, Y.2    Kato, T.3    Suzuki, M.4    Ueno, Y.5
  • 113
    • 84996374193 scopus 로고
    • Simultaneous determination of organophosphorus pesticides by thin-layer chromatography
    • Tsunoda, N. (1986) Simultaneous determination of organophosphorus pesticides by thin-layer chromatography Jpn. J. Toxicol. Environ. Health 32, 447-454
    • (1986) Jpn. J. Toxicol. Environ. Health , vol.32 , pp. 447-454
    • Tsunoda, N.1
  • 114
    • 24844466133 scopus 로고
    • Determination of bis-(beta-chloroethyl) amines and related compounds with 8-quinolinol
    • Trams, E. G. (1958) Determination of bis-(beta-chloroethyl) amines and related compounds with 8-quinolinol Anal. Chem. 30, 256-259
    • (1958) Anal. Chem. , vol.30 , pp. 256-259
    • Trams, E.G.1
  • 115
    • 0017281079 scopus 로고
    • Degradation products of phoxim (Bay-77488) on stored wheat
    • Mason, W. A. and Meloan, C. E. (1976) Degradation products of phoxim (Bay-77488) on stored wheat J. Agric. Food Chem. 24, 299-304
    • (1976) J. Agric. Food Chem. , vol.24 , pp. 299-304
    • Mason, W.A.1    Meloan, C.E.2
  • 116
    • 33747885449 scopus 로고    scopus 로고
    • A screening system for the directed evolution of epoxygenases: Importance of position 184 in P450 BM3 for stereoselective styrene epoxidation
    • DOI 10.1002/anie.200600255
    • Tee, K. L. and Schwaneberg, U. (2006) A screening system for the directed evolution of epoxygenases: Importance of position 184 in P450 BM3 for stereoselective styrene epoxidation Angew. Chem., Int. Ed. 45, 5380-5383 (Pubitemid 44289383)
    • (2006) Angewandte Chemie - International Edition , vol.45 , Issue.32 , pp. 5380-5383
    • Tee, K.L.1    Schwaneberg, U.2
  • 117
    • 0042330460 scopus 로고    scopus 로고
    • Spectrophotometric assay for epoxide hydrolase activity toward any epoxide
    • DOI 10.1016/S0003-2697(03)00399-3
    • Doderer, K., Lutz-Wahl, S., Hauer, B., and Schmid, R. D. (2003) Spectrophotometric assay for epoxide hydrolase activity toward any epoxide Anal. Biochem. 321, 131-134 (Pubitemid 37083273)
    • (2003) Analytical Biochemistry , vol.321 , Issue.1 , pp. 131-134
    • Doderer, K.1    Lutz-Wahl, S.2    Hauer, B.3    Schmid, R.D.4
  • 118
    • 0033522895 scopus 로고    scopus 로고
    • A colorimetric assay suitable for screening epoxide hydrolase activity
    • DOI 10.1016/S0003-2670(99)00216-0, PII S0003267099002160
    • Zocher, F., Enzelberger, M. M., Bornscheuer, U. T., Hauer, B., and Schmid, R. D. (1999) A colorimetric assay suitable for screening epoxide hydrolase activity Anal. Chim. Acta 391, 345-351 (Pubitemid 29299353)
    • (1999) Analytica Chimica Acta , vol.391 , Issue.3 , pp. 345-351
    • Zocher, F.1    Enzelberger, M.M.2    Bornscheuer, U.T.3    Hauer, B.4    Schmid, R.D.5
  • 119
    • 0024588943 scopus 로고
    • The dependence of the mutagenicity of methanesulphonic acid esters in S. typhimurium TA100 on the alkylation mechanism
    • DOI 10.1016/0009-2797(89)90098-7
    • Eder, E. and Kutt, W. (1989) The dependence of the mutagenicity of methanesulfonic acid-esters in S-typhimurium TA100 on the alkylation mechanism Chem.-Biol. Interact 69, 45-59 (Pubitemid 19038489)
    • (1989) Chemico-Biological Interactions , vol.69 , Issue.1 , pp. 45-59
    • Eder, E.1    Kutt, W.2
  • 120
    • 33746352770 scopus 로고    scopus 로고
    • Autoxidative activation of the nematocide 1,3-dichloropropene to highly genotoxic and mutagenic derivatives: Consideration of genotoxic/carcinogenic mechanisms
    • DOI 10.1021/tx060074+
    • Eder, E., Espinosa-González, J., Mayer, A., Reichenberger, K., and Boerth, D. (2006) Autoxidative activation of the nematocide 1,3-dichloropropene to highly genotoxic and mutagenic derivatives: Consideration of genotoxic/carcinogenic mechanisms Chem. Res. Toxicol. 19, 952-959 (Pubitemid 44109658)
    • (2006) Chemical Research in Toxicology , vol.19 , Issue.7 , pp. 952-959
    • Eder, E.1    Espinosa-Gonzalez, J.2    Mayer, A.3    Reichenberger, K.4    Boerth, D.5
  • 121
    • 33750711383 scopus 로고    scopus 로고
    • In vitro induction of micronuclei by monofunctional methanesulphonic acid esters. Possible role of alkylation mechanisms
    • DOI 10.1016/j.cbi.2006.08.020, PII S0009279706002316
    • Eder, E., Kutt, W., and Deininger, C. (2006) In vitro induction of micronuclei by monofunctional methanesulphonic acid esters: Possible role of alkylation mechanisms Chem.-Biol. Interact. 164, 76-84 (Pubitemid 44709713)
    • (2006) Chemico-Biological Interactions , vol.164 , Issue.1-2 , pp. 76-84
    • Eder, E.1    Kutt, W.2    Deininger, C.3
  • 122
    • 84981879181 scopus 로고
    • Carcinogenic epoxides, lactones, and halo-ethers and their mode of action
    • Van Duuren, B. L. (1969) Carcinogenic epoxides, lactones, and halo-ethers and their mode of action Ann. N.Y. Acad. Sci. 163, 633-650
    • (1969) Ann. N.Y. Acad. Sci. , vol.163 , pp. 633-650
    • Van Duuren, B.L.1
  • 123
    • 0016441048 scopus 로고
    • Isolation and identification of products from alkylation of nucleic-acids-ethyl-purines and isopropyl-purines
    • Lawley, P. D., Orr, D. J., and Jarman, M. (1975) Isolation and identification of products from alkylation of nucleic-acids-ethyl-purines and isopropyl-purines Biochem. J. 145, 73-84
    • (1975) Biochem. J. , vol.145 , pp. 73-84
    • Lawley, P.D.1    Orr, D.J.2    Jarman, M.3
  • 124
    • 33847800887 scopus 로고
    • Hard soft acids bases (HSAB) principle in organic chemistry
    • Ho, T. L. (1975) Hard soft acids bases (HSAB) principle in organic chemistry Chem. Rev. 75, 1-20
    • (1975) Chem. Rev. , vol.75 , pp. 1-20
    • Ho, T.L.1
  • 126
    • 77955144553 scopus 로고    scopus 로고
    • Nucleophilicity and site selectivity of commonly used arenes and heteroarenes
    • Pratihar, S. and Roy, S. (2010) Nucleophilicity and site selectivity of commonly used arenes and heteroarenes J. Org. Chem. 75, 4957-4963
    • (2010) J. Org. Chem. , vol.75 , pp. 4957-4963
    • Pratihar, S.1    Roy, S.2
  • 128
    • 0000003828 scopus 로고
    • Quantitative correlation of relative rates. Comparison of hydroxide ion with other nucleophilic reagents toward alkyl halides, esters, epoxides and acyl halides
    • Swain, C. G. and Scott, C. B. (1953) Quantitative correlation of relative rates. Comparison of hydroxide ion with other nucleophilic reagents toward alkyl halides, esters, epoxides and acyl halides J. Am. Chem. Soc. 75, 141-147
    • (1953) J. Am. Chem. Soc. , vol.75 , pp. 141-147
    • Swain, C.G.1    Scott, C.B.2
  • 129
    • 33947090643 scopus 로고
    • Nucleophilic reactivities toward cations
    • Ritchie, C. D. (1972) Nucleophilic reactivities toward cations Acc. Chem. Res. 5, 348-354
    • (1972) Acc. Chem. Res. , vol.5 , pp. 348-354
    • Ritchie, C.D.1
  • 130
    • 0001013344 scopus 로고
    • Cation-anion combination reactions. XIII. Correlation of the reactions of nucleophiles with esters
    • Ritchie, C. D. (1975) Cation-anion combination reactions. XIII. Correlation of the reactions of nucleophiles with esters J. Am. Chem. Soc. 97, 1170-1179
    • (1975) J. Am. Chem. Soc. , vol.97 , pp. 1170-1179
    • Ritchie, C.D.1
  • 131
    • 33749141140 scopus 로고
    • Scales of nucleophilicity and electrophilicity: A system for ordering polar organic and organometallic reactions
    • Mayr, H. and Patz, M. (1994) Scales of nucleophilicity and electrophilicity: a system for ordering polar organic and organometallic reactions Angew. Chem., Int. Ed. 33, 938-957 (Pubitemid 24987579)
    • (1994) Angewandte Chemie (International Edition in English) , vol.33 , Issue.9 , pp. 938-957
    • Mayr, H.1    Patz, M.2
  • 132
    • 0014733394 scopus 로고
    • Methylation of deoxyribonucleic acid in cultured mammalian cells by N-methyl-N′-nitro-N-nitrosoguanidine - Influence of cellular thiol concentrations on extent of methylation and 6-oxygen atom of guanine as a site of methylation
    • Lawley, P. D. and Thatcher, C. J. (1970) Methylation of deoxyribonucleic acid in cultured mammalian cells by N-methyl-N′-nitro-N-nitrosoguanidine- influence of cellular thiol concentrations on extent of methylation and 6-oxygen atom of guanine as a site of methylation Biochem. J. 116, 693
    • (1970) Biochem. J. , vol.116 , pp. 693
    • Lawley, P.D.1    Thatcher, C.J.2
  • 133
    • 0017816766 scopus 로고
    • Alkylation of deoxyribonucleic acid by carcinogens dimethyl sulphate, ethyl methanesulphonate,N-ethyl-N-nitrosurea and N-methyl-N-nitrosurea. Relative reactivity of the phosphodiester site thymidylyl(3'-5')thymidine
    • Swenson, D. H. and Lawley, P. D. (1978) Alkylation of deoxyribonucleic-acid by carcinogens dimethyl sulfate, ethyl methanesulfonate, N-ethyl-N-nitrosourea and N-methyl-N-nitrosourea-relative reactivity of phosphodiester site thymidylyl(3′-5′)thymidine Biochem. J. 171, 575-587 (Pubitemid 8348731)
    • (1978) Biochemical Journal , vol.171 , Issue.3 , pp. 575-587
    • Swenson, D.H.1    Lawley, P.D.2
  • 135
    • 0028301897 scopus 로고
    • A violation of the Swain-Scott principle, and not S(N)1 versus S(N)2 reaction mechanisms, explains why carcinogenic alkylating agents can form different proportions of adducts at oxygen versus nitrogen in DNA
    • Loechler, E. L. (1994) A violation of the Swain-Scott principle, and not SN1 versus SN2 reaction mechanisms, explains why carcinogenic alkylating agents can form different proportions of adducts at oxygen versus nitrogen in DNA Chem. Res. Toxicol. 7, 277-280 (Pubitemid 24150084)
    • (1994) Chemical Research in Toxicology , vol.7 , Issue.3 , pp. 277-280
    • Loechler, E.L.1
  • 136
    • 0025288239 scopus 로고
    • Distribution of methyl and ethyl adducts following alkylation with monofunctional alkylating agents
    • Beranek, D. T. (1990) Distribution of methyl and ethyl adducts following alkylation with monofunctional alkylating agents Mutat. Res.-Fundam. Mol. Mech. Mutag. 231, 11-30 (Pubitemid 20195889)
    • (1990) Mutation Research , vol.231 , Issue.1 , pp. 11-30
    • Beranek, D.T.1
  • 137
    • 0025266025 scopus 로고
    • Nitrosation of aspartic-acid, aspartame, and glycine ethylester: Alkylation of 4-(p -nitrobenzyl)pyridine (NBP) in vitro and binding to DNA in the rat
    • Meier, I., Shephard, S. E., and Lutz, W. K. (1990) Nitrosation of aspartic-acid, aspartame, and glycine ethylester: alkylation of 4-(p -nitrobenzyl)pyridine (NBP) in vitro and binding to DNA in the rat Mutat. Res. 238, 193-201
    • (1990) Mutat. Res. , vol.238 , pp. 193-201
    • Meier, I.1    Shephard, S.E.2    Lutz, W.K.3
  • 138
    • 0025809979 scopus 로고
    • Theoretical structure-activity study of mutagenic allyl chlorides
    • Boerth, D. W., Eder, E., Rasul, G., and Morais, J. (1991) Theoretical structure-activity study of mutagenic allyl chlorides Chem. Res. Toxicol. 4, 368-372
    • (1991) Chem. Res. Toxicol. , vol.4 , pp. 368-372
    • Boerth, D.W.1    Eder, E.2    Rasul, G.3    Morais, J.4
  • 139
    • 0039110778 scopus 로고
    • Development of a monitoring tape for phosgene in air
    • Nakano, N., Yamamoto, A., Kobayashi, Y., and Nagashima, K. (1995) Development of a monitoring tape for phosgene in air Talanta 42, 641-645
    • (1995) Talanta , vol.42 , pp. 641-645
    • Nakano, N.1    Yamamoto, A.2    Kobayashi, Y.3    Nagashima, K.4
  • 140
    • 0028832014 scopus 로고
    • Fluorescent d(CGCGAATTCGCG): Characterization of major groove polarity and study of minor groove interactions through a major groove semantophore conjugate
    • Barawkar, D. A. and Ganesh, K. N. (1995) Fluorescent d(CGCGAATTCGCG): characterization of major groove polarity and study of minor groove interactions through a major groove semantophore conjugate Nucleic Acids Res. 23, 159-164
    • (1995) Nucleic Acids Res. , vol.23 , pp. 159-164
    • Barawkar, D.A.1    Ganesh, K.N.2
  • 141
    • 57249089045 scopus 로고    scopus 로고
    • Improving the spectrophotometric determination of the alkylating activity of anticancer agents: A new insight into the mechanism of the NBP method
    • Dierickx, K. M. E., Journé, F., Gerbaux, P., Morandini, R., Kauffmann, J.-M., and Ghanem, G. E. (2009) Improving the spectrophotometric determination of the alkylating activity of anticancer agents: A new insight into the mechanism of the NBP method Talanta 77, 1370-1375
    • (2009) Talanta , vol.77 , pp. 1370-1375
    • Dierickx, K.M.E.1    Journé, F.2    Gerbaux, P.3    Morandini, R.4    Kauffmann, J.-M.5    Ghanem, G.E.6
  • 142
    • 0023893127 scopus 로고
    • Alkylating activity in food products-especially sauerkraut and sour fermented dairy products-after incubation with nitrite under quasi-gastric conditions
    • Groenen, P. J. and Busink, E. (1988) Alkylating activity in food products-especially sauerkraut and sour fermented dairy products-after incubation with nitrite under quasi-gastric conditions Food Chem. Toxicol. 26, 215-225
    • (1988) Food Chem. Toxicol. , vol.26 , pp. 215-225
    • Groenen, P.J.1    Busink, E.2
  • 143
    • 0024571501 scopus 로고
    • Mutagenicity and alkylating activity in the aqueous chlorination products of humic acid and their molecular weight fractions
    • DOI 10.1016/0048-9697(89)90054-5
    • Agarwal, S. C. and Neton, J. (1989) Mutagenicity and alkylating activity of the aqueous chlorination products of humic-acid and their molecular-weight fractions Sci. Total Environ. 79, 69-83 (Pubitemid 19042445)
    • (1989) Science of the Total Environment , vol.79 , Issue.1 , pp. 69-83
    • Agarwal, S.C.1    Neton, J.2
  • 144
    • 0027142945 scopus 로고
    • Determination of dichlorvos, trichlorfon and their metabolites and degradation products in environmental water, drinks and human urine
    • Katagi, M., Tsuchihashi, H., Hanada, S., Jinmori, H., and Otsuki, K. (1993) Determination of dichlorvos, trichlorfon and their metabolites and degradation products in environmental water, drinks and human urine Jpn. J. Toxicol. Environ. Health 39, 459-468 (Pubitemid 24002296)
    • (1993) Japanese Journal of Toxicology and Environmental Health , vol.39 , Issue.5 , pp. 459-468
    • Katagi, M.1    Tsuchihashi, H.2    Hanada, S.3    Jinmori, H.4    Otsuki, K.5
  • 145
    • 0019457242 scopus 로고
    • Worker environment research: Rapid field method for estimation of organophosphorus insecticide residues on citrus foliage and in grove soil
    • DOI 10.1021/jf00104a001
    • Berck, B., Iwata, Y., and Gunther, F. A. (1981) Worker environment research: Rapid field method for estimation of organo-phosphorus insecticide residues on citrus foliage and in grove soil J. Agric. Food Chem. 29, 209-216 (Pubitemid 11088739)
    • (1981) Journal of Agricultural and Food Chemistry , vol.29 , Issue.2 , pp. 209-216
    • Berck, B.1    Iwata, Y.2    Gunther, F.A.3
  • 146
    • 0025355497 scopus 로고
    • Estimation method of residual alkylating agents in water treated with chloring-containing oxidant
    • Tingfa, D., Shiguang, Z., and Mousheng, T. (1990) Estimation method of residual alkylating agents in water treated with chloring-containing oxidant Water, Air, Soil Pollut. 49, 63-67 (Pubitemid 20131832)
    • (1990) Water, Air, and Soil Pollution , vol.49 , Issue.1-2 , pp. 63-67
    • Tingfa, D.1    Shicang, Z.2    Mousheng, T.3
  • 147
    • 49949133342 scopus 로고
    • 4-(P-Nitrobenzyl)-Pyridin als Reagens zur Dunnschichtchromatographischen Bestimmung verschiedener Azaheterozyklen
    • Guth, J. A. and Manner, L. P. (1967) 4-(P-Nitrobenzyl)-Pyridin als Reagens zur Dunnschichtchromatographischen Bestimmung verschiedener Azaheterozyklen J. Chromatogr. 30, 514-521
    • (1967) J. Chromatogr. , vol.30 , pp. 514-521
    • Guth, J.A.1    Manner, L.P.2
  • 148
    • 0018398177 scopus 로고
    • Evaluation of the alkylating activity of nitrosoureas by thin-layer densitometry
    • Asami, M., Nakamura, K.-I., Kawada, K., and Tanaka, M. (1979) Evaluation of the alkylating activity of nitrosoureas by thin-layer densitometry J. Chromatogr. 174, 216-220 (Pubitemid 9235336)
    • (1979) Journal of Chromatography , vol.174 , Issue.1 , pp. 216-220
    • Asami, M.1    Nakamura, K.2    Kawada, K.3    Tanaka, M.4
  • 149
    • 0019825946 scopus 로고
    • In vitro metabolism of acrylonitrile to 2-cyanoethylene oxide, reaction with glutathione, and irreversible binding to proteins and nucleic acids
    • Guengerich, F. P., Geiger, L. E., Hogy, L. L., and Wright, P. L. (1981) In vitro metabolism of acrylonitrile to 2-cyanoethylene oxide, reaction with glutathione, and irreversible binding to proteins and nucleic acids Cancer Res. 41, 4925-4933 (Pubitemid 12196649)
    • (1981) Cancer Research , vol.41 , Issue.12 , pp. 4925-4933
    • Guengerich, F.P.1    Geiger, L.E.2    Hogy, L.L.3    Wright, P.L.4
  • 150
    • 0025291817 scopus 로고
    • Haloalkene oxidation by the soluble methane monooxygenase from Methylosinus trichosporium OB3b: Mechanistic and environmental implications
    • DOI 10.1021/bi00479a013
    • Fox, B. G., Borneman, J. G., Wackett, L. P., and Lipscomb, J. D. (1990) Haloalkene oxidation by the soluble methane monooxygenase from Methylosinus-trichosporium Ob3b-mechanistic and environmental implications Biochemistry 29, 6419-6427 (Pubitemid 20210794)
    • (1990) Biochemistry , vol.29 , Issue.27 , pp. 6419-6427
    • Fox, B.G.1    Borneman, J.G.2    Wackett, L.P.3    Lipscomb, J.D.4
  • 151
    • 0031019508 scopus 로고    scopus 로고
    • Trichloroethylene oxidation by purified toluene 2-monooxygenase: Products, kinetics, and turnover-dependent inactivation
    • Newman, L. M. and Wackett, L. P. (1997) Trichloroethylene oxidation by purified toluene 2-monooxygenase: Products, kinetics, and turnover-dependent inactivation J. Bacteriol. 179, 90-96 (Pubitemid 26428469)
    • (1997) Journal of Bacteriology , vol.179 , Issue.1 , pp. 90-96
    • Newman, L.M.1    Wackett, L.P.2
  • 152
    • 0033736512 scopus 로고    scopus 로고
    • Epoxide formation from diallyl sulfone is associated with CYP2E1 inactivation in murine and human lungs
    • Forkert, P. G., Premdas, P. D., and Bowers, R. J. (2000) Epoxide formation from diallyl sulfone is associated with CYP2E1 inactivation in murine and human lungs Am. J. Respir. Cell Mol. Biol. 23, 687-695
    • (2000) Am. J. Respir. Cell Mol. Biol. , vol.23 , pp. 687-695
    • Forkert, P.G.1    Premdas, P.D.2    Bowers, R.J.3
  • 154
    • 0008308343 scopus 로고
    • New method for determination of alkylating agents in biologic fluids
    • Tan, Y. L. and Cole, D. R. (1965) New method for determination of alkylating agents in biologic fluids Clin. Chem. 11, 58-62
    • (1965) Clin. Chem. , vol.11 , pp. 58-62
    • Tan, Y.L.1    Cole, D.R.2
  • 155
    • 0016437214 scopus 로고
    • Effect of plasma on reaction of cyclophosphamide with 4-(p -nitrobenzyl)pyridine
    • Cox, P. J. and Farmer, P. B. (1975) Effect of plasma on reaction of cyclophosphamide with 4-(p -nitrobenzyl)pyridine Chem.-Biol. Interact. 10, 103-114
    • (1975) Chem.-Biol. Interact. , vol.10 , pp. 103-114
    • Cox, P.J.1    Farmer, P.B.2
  • 156
    • 0019296497 scopus 로고
    • A stable colorimetric assay for cyclophosphamide and its alkylating metabolites based on the alkylation of 4-(4'-nitrobenzyl)-pyridine
    • DOI 10.1016/0024-3205(80)90545-7
    • Christian, R. A., Chaffee, S. K., Hovick, C. J., and Steele, W. J. (1980) A stable colorimetric assay for cyclophosphamide and its alkylating metabolites based on the alkylation of 4-(4′-nitrobenzyl)-pyridine Life Sci. 27, 2595-2599 (Pubitemid 11133878)
    • (1980) Life Sciences , vol.27 , Issue.25-26 , pp. 2595-2599
    • Christian, R.A.1    Chaffee, S.K.2    Hovick, C.J.3    Steele, W.J.4
  • 157
    • 0034664210 scopus 로고    scopus 로고
    • Reductive activation of mitomycin C by neuronal nitric oxide synthase
    • DOI 10.1016/S0006-2952(00)00346-4, PII S0006295200003464
    • Jiang, H. B., Ichikawa, M., Furukawa, A., Tomita, S., and Ichikawa, Y. (2000) Reductive activation of mitomycin C by neuronal nitric oxide synthase Biochem. Pharmacol. 60, 571-579 (Pubitemid 30389624)
    • (2000) Biochemical Pharmacology , vol.60 , Issue.4 , pp. 571-579
    • Jiang, H.-B.1    Ichikawa, M.2    Furukawa, A.3    Tomita, S.4    Ichikawa, Y.5
  • 158
    • 0001261274 scopus 로고
    • The comparative physiological disposition of ThioTEPA and TEPA in the dog
    • Mellett, L. B. and Woods, L. A. (1960) The comparative physiological disposition of ThioTEPA and TEPA in the dog Cancer Res. 20, 524-532
    • (1960) Cancer Res. , vol.20 , pp. 524-532
    • Mellett, L.B.1    Woods, L.A.2
  • 160
    • 0023896579 scopus 로고
    • 1,2-Epoxycycloalkanes: Substrates and inhibitors of microsomal and cytosolic epoxide hydrolases in mouse liver
    • Magdalou, J. and Hammock, B. D. (1988) 1,2-Epoxycycloalkanes: Substrates and inhibitors of microsomal and cytosolic epoxide hydrolases in mouse liver Biochem. Pharmacol. 37, 2717-2722
    • (1988) Biochem. Pharmacol. , vol.37 , pp. 2717-2722
    • Magdalou, J.1    Hammock, B.D.2
  • 161
    • 0030969017 scopus 로고    scopus 로고
    • Primary structure and catalytic mechanism of the epoxide hydrolase from Agrobacterium radiobacter AD1
    • DOI 10.1074/jbc.272.23.14650
    • Rink, R., Fennema, M., Smids, M., Dehmel, U., and Janssen, D. B. (1997) Primary structure and catalytic mechanism of the epoxide hydrolase from Agrobacterium radiobacter AD1 J. Biol. Chem. 272, 14650-14657 (Pubitemid 27251728)
    • (1997) Journal of Biological Chemistry , vol.272 , Issue.23 , pp. 14650-14657
    • Rink, R.1    Fennema, M.2    Smids, M.3    Dehmel, U.4    Janssen, D.B.5
  • 162
    • 0035807748 scopus 로고    scopus 로고
    • A spectrophotometric method to assay epoxide hydrolase activity
    • DOI 10.1016/S0165-022X(01)00162-2, PII S0165022X01001622
    • Bhatnagar, T., Manoj, K. M., and Baratti, J. C. (2001) A spectrophotometric method to assay epoxide hydrolase activity J. Biochem. Biophys. Methods 50, 1-13 (Pubitemid 33070387)
    • (2001) Journal of Biochemical and Biophysical Methods , vol.50 , Issue.1 , pp. 1-13
    • Bhatnagar, T.1    Manoj, K.M.2    Baratti, J.C.3
  • 163
    • 16544392183 scopus 로고    scopus 로고
    • Colorimetric high-throughput assay for alkene epoxidation catalyzed by cytochrome P450 BM-3 variant 139-3
    • Alcalde, M., Farinas, E. T., and Arnold, F. H. (2004) Colorimetric high-throughput assay for alkene epoxidation catalyzed by cytochrome P450 BM-3 variant 139-3 J. Biomol. Screen. 9, 141-146
    • (2004) J. Biomol. Screen. , vol.9 , pp. 141-146
    • Alcalde, M.1    Farinas, E.T.2    Arnold, F.H.3
  • 164
    • 28444455635 scopus 로고    scopus 로고
    • Colorimetric assays for quantitative analysis and screening of epoxide hydrolase activity
    • DOI 10.1007/s10529-005-3904-1
    • Cedrone, F., Bhatnagar, T., and Baratti, J. C. (2005) Colorimetric assays for quantitative analysis and screening of epoxide hydrolase activity Biotechnol. Lett. 27, 1921-1927 (Pubitemid 41740488)
    • (2005) Biotechnology Letters , vol.27 , Issue.23-24 , pp. 1921-1927
    • Cedrone, F.1    Bhatnagar, T.2    Baratti, J.C.3
  • 166
    • 33746353988 scopus 로고    scopus 로고
    • Enantioselective epoxide hydrolase activity of a newly isolated microorganism, Sphingomonas echinoides EH-983, from seawater
    • DOI 10.1016/j.molcatb.2006.05.009, PII S1381117706001688
    • Kim, H. S., Lee, O. K., Lee, S. J., Hwang, S., Kim, S. J., Yang, S. H., Park, S., and Lee, E. Y. (2006) Enantioselective epoxide hydrolase activity of a newly isolated microorganism, Sphingomonas echinoides EH-983, from seawater J. Mol. Catal. B 41, 130-135 (Pubitemid 44118815)
    • (2006) Journal of Molecular Catalysis B: Enzymatic , vol.41 , Issue.3-4 , pp. 130-135
    • Kim, H.S.1    Lee, O.K.2    Lee, S.J.3    Hwang, S.4    Kim, S.J.5    Yang, S.-H.6    Park, S.7    Lee, E.Y.8
  • 167
    • 68949092012 scopus 로고    scopus 로고
    • Biochemical characterization and transcriptional analysis of the epoxide hydrolase from white-rot fungus phanerochaete chrysosporium
    • Li, N., Zhang, Y., and Feng, H. (2009) Biochemical characterization and transcriptional analysis of the epoxide hydrolase from white-rot fungus phanerochaete chrysosporium Acta Biochim. Biophys. Sin. 41, 638-647
    • (2009) Acta Biochim. Biophys. Sin. , vol.41 , pp. 638-647
    • Li, N.1    Zhang, Y.2    Feng, H.3
  • 168
    • 79957832908 scopus 로고    scopus 로고
    • Homology modelling and site-directed mutagenesis studies of the epoxide hydrolase from Phanerochaete chrysosporium
    • Zhang, L. F., Wu, J. M., and Feng, H. (2011) Homology modelling and site-directed mutagenesis studies of the epoxide hydrolase from Phanerochaete chrysosporium J. Biochem. 149, 673-684
    • (2011) J. Biochem. , vol.149 , pp. 673-684
    • Zhang, L.F.1    Wu, J.M.2    Feng, H.3
  • 169
    • 79960120334 scopus 로고    scopus 로고
    • Cloning and characterization of an epoxide hydrolase from Cupriavidus metallidurans -CH34
    • Kumar, R., Wani, S. I., Chauhan, N. S., Sharma, R., and Sareen, D. (2011) Cloning and characterization of an epoxide hydrolase from Cupriavidus metallidurans -CH34 Protein Expression Purif. 79, 49-59
    • (2011) Protein Expression Purif. , vol.79 , pp. 49-59
    • Kumar, R.1    Wani, S.I.2    Chauhan, N.S.3    Sharma, R.4    Sareen, D.5
  • 170
    • 31344438135 scopus 로고    scopus 로고
    • Enantioselective epoxidation of terminal alkenes to (R)- and (S)-epoxides by engineered cytochromes P450 BM-3
    • DOI 10.1002/chem.200500584
    • Kubo, T., Peters, M. W., Meinhold, P., and Arnold, F. H. (2006) Enantioselective epoxidation of terminal alkenes to (R)- and (S)-epoxides by engineered cytochromes P450 BM-3 Chemistry 12, 1216-1220 (Pubitemid 43145167)
    • (2006) Chemistry - A European Journal , vol.12 , Issue.4 , pp. 1216-1220
    • Kubo, T.1    Peters, M.W.2    Meinhold, P.3    Arnold, F.H.4
  • 171
    • 79951773298 scopus 로고    scopus 로고
    • Rational design of styrene monooxygenase mutants with altered substrate preference
    • Qaed, A. A., Lin, H., Tang, D. F., and Wu, Z. L. (2011) Rational design of styrene monooxygenase mutants with altered substrate preference Biotechnol. Lett. 33, 611-616
    • (2011) Biotechnol. Lett. , vol.33 , pp. 611-616
    • Qaed, A.A.1    Lin, H.2    Tang, D.F.3    Wu, Z.L.4
  • 172
    • 0020446036 scopus 로고
    • Mutagenic properties of allylic and alpha,beta-unsaturated compounds: Consideration of alkylating mechanisms
    • Eder, E., Henschler, D., and Neudecker, T. (1982) Mutagenic properties of allylic and α,β-unsaturated compounds: consideration of alkylating mechanisms Xenobiotica 12, 831-848 (Pubitemid 13195152)
    • (1982) Xenobiotica , vol.12 , Issue.12 , pp. 831-848
    • Eder, E.1    Henschler, D.2    Neudecker, T.3
  • 173
    • 0019239385 scopus 로고
    • Effect of N-alkyl chain length on the mutagenicity of N-nitrosated 1-naphthyl N-alkylcarbamates
    • DOI 10.1002/em.2860020310
    • Eya, B. K. and Talcott, R. E. (1980) Effect of N-Alkyl chain length on the mutagenicity of N-nitrosated 1-naphthyl N-alkylcarbamates Environ. Mol. Mutagen. 2, 395-404 (Pubitemid 12118162)
    • (1980) Environmental Mutagenesis , vol.2 , Issue.3 , pp. 395-404
    • Eya, B.K.1    Talcott, R.E.2
  • 174
    • 0018636357 scopus 로고
    • Mutagenicity of N-methyl-N'-aryl-N-nitrosoureas and N-methyl-N'-aryl-N'- methyl-N-nitrosoureas in relation to their alkylating activity
    • Yano, K. and Isobe, M. (1979) Mutagenicity of N-methyl-N′-aryl-N- nitrosoureas and N-methyl-N′-aryl-N′-methyl-N-nitrosoureas in relation to their alkylating activity Cancer Res. 39, 5147-5149 (Pubitemid 10163131)
    • (1979) Cancer Research , vol.39 , Issue.12 , pp. 5147-5149
    • Yano, K.1    Isobe, M.2
  • 175
    • 0021363330 scopus 로고
    • Interrelationship between tumorigenicity and the chemical nature of N-methyl-N'-aryl-N-nitrosoureas
    • Yano, K., Katayama, H., and Takemoto, K. (1984) Interrelationship between tumorigenicity and the chemical nature of N-methyl-N′-aryl-N-nitrosoureas Cancer Res. 44, 1027-1030 (Pubitemid 14152786)
    • (1984) Cancer Research , vol.44 , Issue.3 , pp. 1027-1030
    • Yano, K.1    Katayama, H.2    Takemoto, K.3
  • 178
    • 0020059920 scopus 로고
    • Comparison of mutagenicity and chemical-properties of N-methyl-N′-alkyl-N-nitrosoureas
    • Isobe, M. and Yano, K. (1982) Comparison of mutagenicity and chemical-properties of N-methyl-N′-alkyl-N-nitrosoureas Mutat. Res. 93, 57-66
    • (1982) Mutat. Res. , vol.93 , pp. 57-66
    • Isobe, M.1    Yano, K.2
  • 180
    • 0021074139 scopus 로고
    • Induction of unscheduled DNA synthesis in HeLa cells by allylic compounds
    • Schiffmann, D., Eder, E., Neudecker, T., and Henschler, D. (1983) Induction of unscheduled DNA synthesis in HeLa cells by allylic compounds Cancer Lett. 20, 263-269
    • (1983) Cancer Lett. , vol.20 , pp. 263-269
    • Schiffmann, D.1    Eder, E.2    Neudecker, T.3    Henschler, D.4
  • 181
    • 0015986836 scopus 로고
    • Interrelationships of some chemical, physicochemical, and biological activities of several 1-(2-haloethyl)-1-nitrosoureas
    • Wheeler, G. P., Bowdon, B. J., Grimsley, J. A., and Lloyd, H. H. (1974) Interrelationships of some chemical, physicochemical, and biological activities of several 1-(2-haloethyl)-1-nitrosoureas Cancer Res. 34, 194-200
    • (1974) Cancer Res. , vol.34 , pp. 194-200
    • Wheeler, G.P.1    Bowdon, B.J.2    Grimsley, J.A.3    Lloyd, H.H.4
  • 182
    • 0027230974 scopus 로고
    • Mechanistic relationship among mutagenicity, skin sensitization, and skin carcinogenicity
    • Ashby, J., Hilton, J., Dearman, R. J., Callander, R. D., and Kimber, I. (1993) Mechanistic relationship among mutagenicity, skin sensitization, and skin carcinogenicity Environ. Health Perspect. 101, 62-67 (Pubitemid 23197122)
    • (1993) Environmental Health Perspectives , vol.101 , Issue.1 , pp. 62-67
    • Ashby, J.1    Hilton, J.2    Dearman, R.J.3    Callander, R.D.4    Kimber, I.5
  • 183
    • 0027138813 scopus 로고
    • Synthesis and evaluation of 1-acyl-1,2-bis(methylsulfonyl)-2-(2- chloroethyl)hydrazines as antineoplastic agents
    • DOI 10.1021/jm00075a002
    • Shyam, K., Penketh, P. G., Divo, A. A., Loomis, R. H., Rose, W. C., and Sartorelli, A. C. (1993) Synthesis and evaluation of 1-acyl-1,2- bis(methylsulfonyl)-2-(2-chloroethyl)hydrazines as antineoplastic agents J. Med. Chem. 36, 3496-3502 (Pubitemid 24004344)
    • (1993) Journal of Medicinal Chemistry , vol.36 , Issue.23 , pp. 3496-3502
    • Shyam, K.1    Penketh, P.G.2    Divo, A.A.3    Loomis, R.H.4    Rose, W.C.5    Sartorelli, A.C.6
  • 184
    • 0024834420 scopus 로고
    • Characterization of the DNA-DNA cross-linking activity of 3'-(3-cyano-4-morpholinyl)-3'-deaminoadriamycin
    • Jesson, M. I., Johnston, J. B., Robotham, E., and Begleiter, A. (1989) Characterization of the DNA-DNA cross-linking activity of 3′-(3-cyano-4- morpholinyl)-3′-deaminoadriamycin Cancer Res. 49, 7031-7036 (Pubitemid 20016588)
    • (1989) Cancer Research , vol.49 , Issue.24 , pp. 7031-7036
    • Jesson, M.I.1    Johnston, J.B.2    Robotham, E.3    Begleiter, A.4
  • 185
    • 0028451732 scopus 로고
    • Gas-phase ion-molecule reactions: A model for the determination of biologically reactive electrophilic contaminants in the environment
    • Freeman, J. A., Johnson, J. V., Yost, R. A., and Kuehl, D. W. (1994) Gas-phase ion-molecule reactions: a model for the determination of biologically reactive electrophilic contaminants in the environment Anal. Chem. 66, 1902-1910
    • (1994) Anal. Chem. , vol.66 , pp. 1902-1910
    • Freeman, J.A.1    Johnson, J.V.2    Yost, R.A.3    Kuehl, D.W.4
  • 187
    • 0031981046 scopus 로고    scopus 로고
    • Albumin conjugates of the anticancer drug chlorambucil: Synthesis, characterization, and in vitro efficacy
    • DOI 10.1002/(SICI)1521-4184(199802)331:2<47::AID-ARDP47>3.0.CO;2-R
    • Kratz, F., Beyer, U., Roth, T., Schütte, M. T., Unold, A., Fiebig, H. H., and Unger, C. (1998) Albumin conjugates of the anticancer drug chlorambucil: synthesis, characterization, and in vitro efficacy Arch. Pharm. 331, 47-53 (Pubitemid 28164094)
    • (1998) Archiv der Pharmazie , vol.331 , Issue.2 , pp. 47-53
    • Kratz, F.1    Beyer, U.2    Roth, T.3    Schutte, M.T.4    Unold, A.5    Fiebig, H.H.6    Unger, C.7
  • 188
    • 0014861224 scopus 로고
    • Structure and activity in chemical carcinogenesis: Reactivity and carcinogenicity of 7-bromomethylbenz[a]anthracene and 7-bromomethyl-12- methylbenz[a]anthracene
    • Dipple, A. and Slade, T. A. (1970) Structure and activity in chemical carcinogenesis: Reactivity and carcinogenicity of 7-bromomethylbenz[a]anthracene and 7-bromomethyl-12-methylbenz[a]anthracene Eur. J. Cancer 6, 417-423
    • (1970) Eur. J. Cancer , vol.6 , pp. 417-423
    • Dipple, A.1    Slade, T.A.2
  • 189
    • 0013857875 scopus 로고
    • Carcinogenicity of epoxides, lactones, and peroxy compounds. III. biological activity and chemical reactivity
    • Van Duuren, B. L. and Goldschmidt, B. M. (1966) Carcinogenicity of epoxides, lactones, and peroxy compounds. III. biological activity and chemical reactivity J. Med. Chem. 9, 77-79
    • (1966) J. Med. Chem. , vol.9 , pp. 77-79
    • Van Duuren, B.L.1    Goldschmidt, B.M.2
  • 190
    • 0018877345 scopus 로고
    • Determination of reaction rate constants for alkylation of 4-(p-nitrobenzyl) pyridine by different alkylating agents
    • DOI 10.1016/0378-4274(80)90167-8
    • Walles, S. A. S. (1980) Determination of reaction-rate constants for alkylation of 4-(p -nitrobenzyl)pyridine by different alkylating-agents Toxicol. Lett. 5, 161-167 (Pubitemid 10138573)
    • (1980) Toxicology Letters , vol.5 , Issue.2 , pp. 161-167
    • Walles, S.A.S.1
  • 191
    • 0015425134 scopus 로고
    • Epoxy derivatives of aromatic polycyclic hydrocarbons: Synthesis of dibenz[a,c]anthracene 10,11-oxide and its metabolism by rat-liver preparations
    • Sims, P. (1972) Epoxy derivatives of aromatic polycyclic hydrocarbons: synthesis of dibenz[a,c]anthracene 10,11-oxide and its metabolism by rat-liver preparations Biochem. J. 130, 27-35
    • (1972) Biochem. J. , vol.130 , pp. 27-35
    • Sims, P.1
  • 193
    • 0017811873 scopus 로고
    • Some properties of vicinal diol-epoxides derived from benz(a)anthracene and benzo(a)pyrene
    • DOI 10.1016/0009-2797(78)90081-9
    • Phillips, D. H., Grover, P. L., and Sims, P. (1978) Some properties of vicinal diol-epoxides derived from benz(a)anthracene and benzo(a)pyrene Chem.-Biol. Interact. 20, 63-75 (Pubitemid 8271570)
    • (1978) Chemico-Biological Interactions , vol.20 , Issue.1 , pp. 63-75
    • Phillips, D.H.1    Grover, P.L.2    Sims, P.3
  • 194
    • 0016852042 scopus 로고
    • Cyclophosphamide, 2,2-dimethylaziridines and other alkylating-agents as inhibitors of serum-cholinesterase
    • Lalka, D. and Bardos, T. J. (1975) Cyclophosphamide, 2,2- dimethylaziridines and other alkylating-agents as inhibitors of serum-cholinesterase Biochem. Pharmacol. 24, 455-462
    • (1975) Biochem. Pharmacol. , vol.24 , pp. 455-462
    • Lalka, D.1    Bardos, T.J.2
  • 195
    • 0023013870 scopus 로고
    • Comparison of the chemical reactivities and antineoplastic activities of alpha,beta-, alpha,beta'-, beta,beta'-, and alpha,alpha'-bis[[[(2-propylamino) carbonyl]oxy]methyl]-substituted pyrroles
    • DOI 10.1021/jm00161a042
    • Anderson, W. K. and Heider, A. R. (1986) Vinylogous carbinolamine tumor inhibitors. 20. comparison of the chemical reactivities and antineoplastic activities of alpha,beta, alpha,beta′, beta,beta′, and alpha,alpha′-bis[[[(2-propylamino)carbonyl]oxy]methyl]-substituted pyrroles J. Med. Chem. 29, 2392-2395 (Pubitemid 17182324)
    • (1986) Journal of Medicinal Chemistry , vol.29 , Issue.11 , pp. 2392-2395
    • Anderson, W.K.1    Heider, A.R.2
  • 198
    • 0023926239 scopus 로고
    • Evidence for an episulfonium ion intermediate in the formation of S-[2-(N7-guanyl)ethyl]glutathione in DNA
    • Peterson, L. A., Harris, T. M., and Guengerich, F. P. (1988) Evidence for an episulfonium ion intermediate in the formation of S-[2-(N7-guanyl)ethyl] glutathione in DNA J. Am. Chem. Soc. 110, 3284-3291
    • (1988) J. Am. Chem. Soc. , vol.110 , pp. 3284-3291
    • Peterson, L.A.1    Harris, T.M.2    Guengerich, F.P.3
  • 201
    • 0001710524 scopus 로고
    • The initial rate method in chemical kinetics: Evaluation and experimental illustration
    • Casado, J., Loýpez-Quintela, M. A., and Lorenzo-Barral, F. M. (1986) The initial rate method in chemical kinetics: Evaluation and experimental illustration J. Chem. Educ. 63, 450
    • (1986) J. Chem. Educ. , vol.63 , pp. 450
    • Casado, J.1    Loýpez-Quintela, M.A.2    Lorenzo-Barral, F.M.3
  • 202
    • 33845282405 scopus 로고
    • Kinetics of alkylation reactions of pyrrolizidine alkaloid pyrroles
    • Karchesy, J. J., Arbogast, B., and Deinzer, M. L. (1987) Kinetics of alkylation reactions of pyrrolizidine alkaloid pyrroles J. Org. Chem. 52, 3867-3872
    • (1987) J. Org. Chem. , vol.52 , pp. 3867-3872
    • Karchesy, J.J.1    Arbogast, B.2    Deinzer, M.L.3
  • 203
    • 0032717143 scopus 로고    scopus 로고
    • The relationship between reactivity of metabolites of pyrrolizidine alkaloids and extrahepatic toxicity
    • Cooper, R. A. and Huxtable, R. J. (1999) The Relationship between Reactivity of Metabolites of Pyrrolizidine Alkaloids and Extrahepatic Toxicity, in Proceedings of the Forty-Second Annual Meeting of the Western Pharmacology Society (Huxtable, R., Ed.) WPS, Reno, NV, pp 13-16. (Pubitemid 29513903)
    • (1999) Proceedings of the Western Pharmacology Society , vol.42 , pp. 13-16
    • Cooper, R.A.1    Huxtable, R.J.2
  • 204
    • 0025215884 scopus 로고
    • Nucleophilic selectivity and reaction kinetics of chloroethylene oxide assessed by the 4-(p-nitrobenzyl)pyridine assay and proton nuclear magnetic resonance spectroscopy
    • Barbin, A., Bereziat, J. C., Croisy, A., Oneill, I. K., and Bartsch, H. (1990) Nucleophilic selectivity and reaction-kinetics of chloroethylene oxide assessed by the 4-(p -nitrobenzyl)pyridine assay and proton nuclear magnetic resonance spectroscopy Chem.-Biol. Interact. 73, 261-277 (Pubitemid 20097190)
    • (1990) Chemico-Biological Interactions , vol.73 , Issue.2-3 , pp. 261-277
    • Barbin, A.1    Bereziat, J.-C.2    Croisy, A.3    O'Neill, I.K.4    Bartsch, H.5
  • 205
    • 0037046575 scopus 로고    scopus 로고
    • Synthesis and in vitro evaluation of quaternary ammonium derivatives of chlorambucil and melphalan, anticancer drugs designed for the chemotherapy of chondrosarcoma
    • DOI 10.1021/jm010926x
    • Giraud, I., Rapp, M., Maurizis, J.-C., and Madelmont, J.-C. (2002) Synthesis and in vitro evaluation of quaternary ammonium derivatives of chlorambucil and melphalan, anticancer drugs designed for the chemotherapy of chondrosarcoma J. Med. Chem. 45, 2116-2119 (Pubitemid 34477724)
    • (2002) Journal of Medicinal Chemistry , vol.45 , Issue.10 , pp. 2116-2119
    • Giraud, I.1    Rapp, M.2    Maurizis, J.-C.3    Madelmont, J.-C.4
  • 206
    • 0023236184 scopus 로고
    • Linear free energy relationships and cytotoxicities of para-substituted 2-haloethyl aryl selenides and bis(2-chloroethyl) selenides
    • DOI 10.1021/jm00387a003
    • Kagn, S. I. and Spears, C. P. (1987) Linear free energy relationships and cytotoxicities of para-substituted 2-haloethyl aryl selenides and bis(2-chloroethyl) selenides J. Med. Chem. 30, 597-602 (Pubitemid 17065190)
    • (1987) Journal of Medicinal Chemistry , vol.30 , Issue.4 , pp. 597-602
    • Kang, S.-I.1    Spears, C.P.2
  • 212
    • 0019519218 scopus 로고
    • Nucleophilic selectivity ratios of model and clinical alkylating agents by 4-(4'-nitrobenzyl)pyridine competition
    • Spears, C. P. (1981) Nucleophilic selectivity ratios of model and clinical alkylating agents by 4-(4′-nitrobenzyl)pyridine competition Mol. Pharmacol. 19, 496-504 (Pubitemid 11117317)
    • (1981) Molecular Pharmacology , vol.19 , Issue.3 , pp. 496-504
    • Spears, C.P.1
  • 213
    • 0036411957 scopus 로고    scopus 로고
    • Mutagenicity of bisphenol A (4,4-isopropylidenediphenol) in vitro: Effects of nitrosylation
    • DOI 10.1002/tcm.10039
    • Schrader, T. J., Langlois, I., Soper, K., and Cherry, W. (2002) Mutagenicity of bisphenol A (4,4′-isopropylidenediphenol) in vitro: Effects of nitrosylation Teratog. Carcinog. Mutagen. 22, 425-441 (Pubitemid 35266453)
    • (2002) Teratogenesis Carcinogenesis and Mutagenesis , vol.22 , Issue.6 , pp. 425-441
    • Schrader, T.J.1    Langlois, I.2    Soper, K.3    Cherry, W.4
  • 214
    • 0026602014 scopus 로고
    • 4-(4-Nitrobenzyl)pyridine tests for alkylating-agents following chemical oxidative activation
    • Thomas, J. J., Kim, J. H., and Mauro, D. M. (1992) 4-(4-Nitrobenzyl) pyridine tests for alkylating-agents following chemical oxidative activation Arch. Environ. Contam. Toxicol. 22, 219-227
    • (1992) Arch. Environ. Contam. Toxicol. , vol.22 , pp. 219-227
    • Thomas, J.J.1    Kim, J.H.2    Mauro, D.M.3
  • 215
    • 0032501069 scopus 로고    scopus 로고
    • Detection of in vivo genotoxicity of haloalkanes and haloalkenes carcinogenic to rodents by the alkaline single cell gel electrophoresis (comet) assay in multiple mouse organs
    • DOI 10.1016/S1383-5718(98)00114-4, PII S1383571898001144
    • Sasaki, Y. F., Saga, A., Akasaka, M., Ishibashi, S., Yoshida, K., Su, Y. Q., Matsusaka, N., and Tsuda, S. (1998) Detection of in vivo genotoxicity of haloalkanes and haloalkenes carcinogenic to rodents by the alkaline single cell gel electrophoresis (comet) assay in multiple mouse organs Mutat. Res., Genet. Toxicol. Environ. Mutagen. 419, 13-20 (Pubitemid 28512967)
    • (1998) Mutation Research - Genetic Toxicology and Environmental Mutagenesis , vol.419 , Issue.1-3 , pp. 13-20
    • Sasaki, Y.F.1    Saga, A.2    Akasaka, M.3    Ishibashi, S.4    Yoshida, K.5    Su, Y.Q.6    Matsusaka, N.7    Tsuda, S.8
  • 216
    • 24044551627 scopus 로고    scopus 로고
    • The in vivo comet assay: Use and status in genotoxicity testing
    • DOI 10.1093/mutage/gei033
    • Brendler-Schwaab, S., Hartmann, A., Pfuhler, S., and Speit, G. (2005) The in vivo comet assay: use and status in genotoxicity testing Mutagenesis 20, 245-254 (Pubitemid 41399464)
    • (2005) Mutagenesis , vol.20 , Issue.4 , pp. 245-254
    • Brendler-Schwaab, S.1    Hartmann, A.2    Pfuhler, S.3    Speit, G.4
  • 217
    • 77951662689 scopus 로고    scopus 로고
    • Dose-response assessment of four genotoxic chemicals in a combined mouse and rat micronucleus (MN) and Comet assay protocol
    • Recio, L., Hobbs, C., Caspary, W., and Witt, K. L. (2010) Dose-response assessment of four genotoxic chemicals in a combined mouse and rat micronucleus (MN) and Comet assay protocol J. Toxicol. Sci. 35, 149-162
    • (2010) J. Toxicol. Sci. , vol.35 , pp. 149-162
    • Recio, L.1    Hobbs, C.2    Caspary, W.3    Witt, K.L.4
  • 218
    • 69049112943 scopus 로고    scopus 로고
    • Acrylonitrile-induced oxidative stress and oxidative DNA damage in male Sprague-Dawley rats
    • Pu, X., Kamendulis, L. M., and Klaunig, J. E. (2009) Acrylonitrile- induced oxidative stress and oxidative DNA damage in male Sprague-Dawley rats Toxicol. Sci. 111, 64-71
    • (2009) Toxicol. Sci. , vol.111 , pp. 64-71
    • Pu, X.1    Kamendulis, L.M.2    Klaunig, J.E.3
  • 219
    • 80155163022 scopus 로고    scopus 로고
    • Assessment of genotoxicity induced by 7,12-dimethylbenz(a)anthracene or diethylnitrosamine in the Pig-a, micronucleus and Comet assays integrated into 28-day repeat dose studies
    • Shi, J., Krsmanovic, L., Bruce, S., Kelly, T., Paranjpe, M., Szabo, K., Arévalo, M., Atta-Safoh, S., Debelie, F., LaForce, M. K., Sly, J., and Springer, S. (2011) Assessment of genotoxicity induced by 7,12-dimethylbenz(a) anthracene or diethylnitrosamine in the Pig-a, micronucleus and Comet assays integrated into 28-day repeat dose studies Environ. Mol. Mutag. 52, 711-720
    • (2011) Environ. Mol. Mutag. , vol.52 , pp. 711-720
    • Shi, J.1    Krsmanovic, L.2    Bruce, S.3    Kelly, T.4    Paranjpe, M.5    Szabo, K.6    Arévalo, M.7    Atta-Safoh, S.8    Debelie, F.9    Laforce, M.K.10    Sly, J.11    Springer, S.12
  • 220
    • 0031869362 scopus 로고    scopus 로고
    • Organ-specific genotoxicity of the potent rodent colon carcinogen 1,2-dimethylhydrazine and three hydrazine derivatives: Difference between intraperitoneal and oral administration
    • DOI 10.1016/S1383-5718(98)00002-3, PII S1383571898000023
    • Sasaki, Y. F., Saga, A., Akasaka, M., Ishibashi, S., Yoshida, K., Su, Y. Q., Matsusaka, N., and Tsuda, S. (1998) Organ-specific genotoxicity of the potent rodent colon carcinogen 1,2-dimethylhydrazine and three hydrazine derivatives: difference between intraperitoneal and oral administration Mutat. Res., Genet. Toxicol. Environ. Mutagen. 415, 1-12 (Pubitemid 28377242)
    • (1998) Mutation Research - Genetic Toxicology and Environmental Mutagenesis , vol.415 , Issue.1-2 , pp. 1-12
    • Sasaki, Y.F.1    Saga, A.2    Akasaka, M.3    Ishibashi, S.4    Yoshida, K.5    Su, Y.Q.6    Matsusaka, N.7    Tsuda, S.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.