Genotoxicity profiles of common alkyl halides and esters with alkylating activity

Mutation Research - Genetic Toxicology and Environmental Mutagenesis

Volumn 633, Issue 2, 2007, Pages 80-94

  Sobol, Z ^a   Engel, M E ^b   Rubitski, E ^b   Ku, W W ^b   Aubrecht, J ^b   Schiestl, R H ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b PFIZER INC   (United States)

Author keywords

Alkyl esters; Alkyl halides; Alkylating agents; CHO cells; Clastogenicity; DEL; Deletion; Genotoxicity; Micronucleus; NBP; S. cerevisiae; Yeast

Indexed keywords

4 (4 NITROBENZYL)PYRIDINE; ALKANE; ALKYLATING AGENT; ARYLSULFONIC ACID DERIVATIVE; BENZENESULFONIC ACID DERIVATIVE; CHLORIDE; CLASTOGEN; DIETHYL SULFATE; DIMETHYL SULFATE; ESTER; HALIDE; MESYLIC ACID ETHYL ESTER; MESYLIC ACID METHYL ESTER; NITROGEN; SULFONIC ACID DERIVATIVE; SULFURIC ACID; TOLUENESULFONIC ACID DERIVATIVE;

ALKYLATION; ANIMAL CELL; ARTICLE; CARCINOGENESIS; CHO CELL; CONTROLLED STUDY; CORRELATION ANALYSIS; DNA STRAND BREAKAGE; GENE DELETION; GENE REARRANGEMENT; GENOTOXICITY; IN VITRO STUDY; MICRONUCLEUS; MICRONUCLEUS TEST; NONHUMAN; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE; SALMONELLA; YEAST;

ALKYLATING AGENTS; ALKYLATION; ANIMALS; CHO CELLS; CRICETINAE; CRICETULUS; DNA DAMAGE; ESTERS; GENE DELETION; MICRONUCLEUS TESTS; MUTAGENICITY TESTS; MUTAGENS; SACCHAROMYCES CEREVISIAE; SULFONIC ACIDS; SULFURIC ACID ESTERS;

SALMONELLA;

EID: 34547733084     PISSN: 13835718     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mrgentox.2007.05.004     Document Type: Article

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