RNase MC2: A new Momordica charantia ribonuclease that induces apoptosis in breast cancer cells associated with activation of MAPKs and induction of caspase pathways

Apoptosis

Volumn 17, Issue 4, 2012, Pages 377-387

  Fang, Evandro Fei ^a   Zhang, Chris Zhi Yi ^b   Fong, Wing Ping ^c   Ng, Tzi Bun ^a,c  

^a Prince of Wales Hospital   (Hong Kong)

^b SUN YAT SEN UNIVERSITY CANCER CENTER   (China)

^c CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Breast cancer; Caspase pathway; Momordica charantia; Ribonuclease; Therapy

Indexed keywords

CASPASE; CASPASE 7; CASPASE 8; CASPASE 9; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; MOMORDICA CHARANTIA EXTRACT; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; RIBONUCLEASE; RIBONUCLEASE MC2; TRANSFER RNA; UNCLASSIFIED DRUG; URIDINE;

APOPTOSIS; ARTICLE; BREAST CANCER; CANCER CELL; CELL STRAIN MCF 7; CHROMATIN CONDENSATION; CONTROLLED STUDY; CYTOTOXICITY; DNA FRAGMENTATION; DRUG ANALYSIS; DRUG PURIFICATION; HUMAN; HUMAN CELL; MOMORDICA CHARANTIA; NONHUMAN; PRIORITY JOURNAL; RNA CLEAVAGE; SIGNAL TRANSDUCTION;

AMINO ACID SEQUENCE; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; BREAST NEOPLASMS; CASPASE 7; CASPASE 8; CASPASE 9; CASPASES; CELL LINE, TUMOR; FEMALE; HUMANS; MITOGEN-ACTIVATED PROTEIN KINASES; MOLECULAR SEQUENCE DATA; MOMORDICA CHARANTIA; PROTO-ONCOGENE PROTEINS C-AKT; RIBONUCLEASES; SEEDS; SEQUENCE ALIGNMENT;

MOMORDICA CHARANTIA;

EID: 84862504382     PISSN: 13608185     EISSN: 1573675X     Source Type: Journal    
DOI: 10.1007/s10495-011-0684-z     Document Type: Article

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