Oligonucleosome DNA fragmentation of caspase 3 deficient MCF-7 cells in palmitate-induced apoptosis

Nucleosides, Nucleotides and Nucleic Acids

Volumn 23, Issue 6-7, 2004, Pages 831-836

  Semenov, D V ^a   Aronov, P A ^a   Kuligina, E V ^a   Potapenko, M O ^a   Richter, V A ^a  

^a INSTITUTE OF CHEMICAL BIOLOGY AND FUNDAMENTAL MEDICINE   (Russian Federation)

Author keywords

Apoptosis; Caspase 3; Caspase 7; Caspase activated DNAse; DNA fragmentation; MCF 7

Indexed keywords

CASPASE 3; CASPASE 7; CASPASE 9; DEOXYRIBONUCLEASE; DNA FRAGMENT; PACLITAXEL; PALMITIC ACID; STAUROSPORINE;

APOPTOSIS; CATALYSIS; CELL FREE SYSTEM; CELL STRAIN MCF 7; CONFERENCE PAPER; ENZYME ACTIVATION; ENZYME DEFICIENCY; ENZYME INDUCTION; HUMAN; HUMAN CELL; MAMMAL CELL; MICROSOME; NUCLEOSOME; OLIGONUCLEOSOME; POLYACRYLAMIDE GEL ELECTROPHORESIS;

ANIMALS; APOPTOSIS; CASPASE 3; CASPASES; CELL LINE, TUMOR; CHO CELLS; CRICETINAE; ELECTROPHORESIS, POLYACRYLAMIDE GEL; HUMANS; PALMITIC ACID; POLYMERASE CHAIN REACTION; TUMOR NECROSIS FACTOR-ALPHA;

MAMMALIA; MINK CELL FOCUS-FORMING VIRUS;

EID: 7644240644     PISSN: 15257770     EISSN: None     Source Type: Journal    
DOI: 10.1081/NCN-200026024     Document Type: Conference Paper

References (11)

1. Cryns, V.; Yuan, J. Proteases to die for. Genes Dev. 1998, 12, 1551-1570.
2. Cohen, G.M. Caspases: the executioners of apoptosis. Biochem J. 1997, 326, 1-16.
3. Janicke, R.U.; Sprengart, M.L.; Wati, M.R.; Porter, A.G. Caspase-3 is required for DNA fragmentation and morphological changes associated with apoptosis. J. Biol. Chem. 1998, 273, 9357-9360.
4. McGee, M.M.; Hyland, E.; Campiani, G.; Ramunno, A.; Nacci, V.; Zisterer, D.M. Caspase-3 is not essential for DNA fragmentation in MCF-7 cells during apoptosis induced by the pyrrolo-1,5-benzoxazepine, PBOX-6. FEBS Lett. 2002, 515, 66-70.
5. Mooney, L.M.; Al-Sakkaf, K.A.; Brown, B.L.; Dobson, P.R. Apoptotic mechanisms in T47D and MCF-7 human breast cancer cells. Br. J. Cancer 2002, 87, 909-917.
6. Kottke, T.J.; Blajeski, A.L.; Meng, X.W.; Svingen, P.A.; Ruchaud, S.; Mesner, P.W., Jr.; Boerner, S.A.; Samejima, K.; Henriquez, N.V.; Chilcote, T.J.; Lord, J.; Salmon, M.; Earnshaw, W.C.; Kaufmann, S.H. Lack of correlation between caspase activation and caspase activity assays in paclitaxel-treated MCF-7 breast cancer cells. J. Biol. Chem. 2002, 277, 804-815.
7. de Pablo, M.A.; Susin, S.A.; Jacotot, E.; Larochette, N.; Costantini, P.; Ravagnan, L.; Zamzami, N.; Kroemer, G. Palmitate induces apoptosis via a direct effect on mitochondria. Apoptosis 1999, 4, 81-87.
8. Kaufmann, S.H.; Mesner, P.W., Jr.; Samejima, K.; Tone, S.; Earnshaw, W.C. Detection of DNA cleavage in apoptotic cells. Methods Enzymol. 2000, 322, 3-15.
9. Rickwood, D.; Messent, A.; Patel, D.; Hinton, R.H.; Mullock, B.M. Isolation of subcellular fragments. In Subcellular Fractionation-A Practical Approach; Graham, J.M., Rickwood, D., Eds.; Oxford University Press: Oxford, UK, 1997; 75-76.
10. Chang, H.Y.; Yang, X. Proteases for cell suicide: functions and regulation of caspases. Microbiol. Mol. Biol. Rev. 2000, 64, 821-846.
11. Chandler, J.M.; Cohen, G.M.; MacFarlane, M. Different subcellular distribution of caspase-3 and caspase-7 following Fas-induced apoptosis in mouse liver. J. Biol. Chem. 1998, 273, 10815-10818.