Claudin 18 is a novel negative regulator of bone resorption and osteoclast differentiation

Journal of Bone and Mineral Research

Volumn 27, Issue 7, 2012, Pages 1553-1565

  Linares, Gabriel R ^a,b   Brommage, Robert ^c   Powell, David R ^c   Xing, Weirong ^a,b   Chen, Shin Tai ^a,b   Alshbool, Fatima Z ^a,b   Lau, K H William ^a,b   Wergedal, Jon E ^a,b   Mohan, Subburaman ^a,b  

^a Jerry L Pettis Memorial VA Medical Center   (United States)

^b LOMA LINDA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c LEXICON PHARMACEUTICALS INC   (United States)

Author keywords

Claudin 18; Osteoclasts; Resorption; Tight junctions; Zonula occludens

Indexed keywords

ACID PHOSPHATASE TARTRATE RESISTANT ISOENZYME; BIOLOGICAL MARKER; CALCIUM; CLAUDIN 18; COLONY STIMULATING FACTOR 1; HISTONE H3; MEMBRANE PROTEIN; MESSENGER RNA; OSTEOCLAST DIFFERENTIATION FACTOR; PDZ PROTEIN; PHOSPHATASE; PROTEIN ZO2; TARTRATE RESISTANT ACID PHOSPHATASE 5B; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE DENSITY; BONE MARROW CELL; BONE MINERAL; CALCIUM DEFICIENCY; CELL DIFFERENTIATION; CONTROLLED STUDY; CORTICAL BONE; FEMALE; FEMUR; GENE EXPRESSION; IN VITRO STUDY; MACROPHAGE; MALE; MORPHOMETRICS; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OSSIFICATION; OSTEOCLAST; OSTEOLYSIS; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN FAMILY; PROTEIN MOTIF; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; THICKNESS; TIGHT JUNCTION; TRABECULAR BONE; VERTEBRA; WILD TYPE;

ANIMALS; BONE MARROW CELLS; BONE RESORPTION; CELL DIFFERENTIATION; CELL PROLIFERATION; CLAUDINS; FEMALE; GENOTYPE; MEMBRANE PROTEINS; MICE; MICE, TRANSGENIC; OSTEOCLASTS; RANK LIGAND; TIGHT JUNCTIONS;

EID: 84862495965     PISSN: 08840431     EISSN: 15234681     Source Type: Journal    
DOI: 10.1002/jbmr.1600     Document Type: Article

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