Claudin 14 knockout mice, a model for autosomal recessive deafness DFNB29, are deaf due to cochlear hair cell degeneration

Human Molecular Genetics

Volumn 12, Issue 16, 2003, Pages 2049-2061

  Ben Yosef, Tamar ^a   Belyantseva, Inna A ^a   Saunders, Thomas L ^b   Hughes, Elizabeth D ^b   Kawamoto, Kohei ^b,g   Van Itallie, Christina M ^c   Beyer, Lisa A ^b   Halsey, Kärin ^b   Gardner, Donald J ^d   Wilcox, Edward R ^a   Rasmussen, Julia ^e   Anderson, James M ^e   Dolan, David F ^b   Forge, Andrew ^f   Raphael, Yehoash ^b   Camper, Sally A ^b   Friedman, Thomas B ^a  

^a NATIONAL INSTITUTE ON DEAFNESS AND OTHER COMMUNICATION DISORDERS   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^d NATIONAL INSTITUTES OF HEALTH   (United States)

^e UNIVERSITY OF NORTH CAROLINA   (United States)

^f UNIVERSITY COLLEGE LONDON   (United Kingdom)

^g KANSAI MEDICAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BETA GALACTOSIDASE; CATION; CLAUDIN; CLAUDIN 14; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; AUTOSOMAL RECESSIVE DISORDER; CELL DEGENERATION; CELL MEMBRANE PERMEABILITY; CELL STRAIN; CELL SURFACE; COCHLEA; COCHLEA POTENTIAL; CONTROLLED STUDY; DATA ANALYSIS; ELECTRIC RESISTANCE; ENZYME ACTIVITY; EPITHELIUM CELL; EXTERNAL EAR; FEMALE; GENE CASSETTE; GENE DELETION; GENE EXPRESSION; GENE TARGETING; HAIR CELL; HEARING IMPAIRMENT; HETEROZYGOSITY; IMMUNOLOCALIZATION; INNER EAR; KIDNEY COLLECTING TUBULE; KNOCKOUT MOUSE; LIVER; MALE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; NULL ALLELE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN FUNCTION; REVIEW; TIGHT JUNCTION; WILD TYPE;

ANIMALS; ANIMALS, NEWBORN; CELL MEMBRANE PERMEABILITY; COCHLEA; DEAFNESS; EAR, INNER; FEMALE; HAIR CELLS; MALE; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NERVE DEGENERATION; ORGAN OF CORTI; SEQUENCE DELETION; TIGHT JUNCTIONS;

ANIMALIA;

EID: 10744222330     PISSN: 09646906     EISSN: None     Source Type: Journal    
DOI: 10.1093/hmg/ddg210     Document Type: Review

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