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Volumn 23, Issue 7, 2012, Pages 822-828

High-fat diets rich in soy or fish oil distinctly alter hypothalamic insulin signaling in rats

Author keywords

Food intake; High fat feeding; Hypothalamus; Insulin hypophagia; Insulin signaling; Obesity; Polyunsaturated fatty acids

Indexed keywords

CORTICOSTERONE; FISH OIL; INSULIN; INSULIN RECEPTOR SUBSTRATE 1; LEPTIN; LIPID; PROTEIN KINASE B; SOYBEAN OIL;

EID: 84862337042     PISSN: 09552863     EISSN: 18734847     Source Type: Journal    
DOI: 10.1016/j.jnutbio.2011.04.006     Document Type: Article
Times cited : (27)

References (49)
  • 1
    • 34248393099 scopus 로고    scopus 로고
    • High-fat diets: modeling the metabolic disorders of human obesity in rodents
    • Buettner R., Scholmerich J., Bollheimer L.C. High-fat diets: modeling the metabolic disorders of human obesity in rodents. Obesity 2007, 5:798-808.
    • (2007) Obesity , vol.5 , pp. 798-808
    • Buettner, R.1    Scholmerich, J.2    Bollheimer, L.C.3
  • 2
    • 46449123205 scopus 로고    scopus 로고
    • The importance of the omega-6/omega-3 fatty acid ratio in cardiovascular disease and other chronic diseases
    • Simopoulos A.P. The importance of the omega-6/omega-3 fatty acid ratio in cardiovascular disease and other chronic diseases. Exp Biol Med 2008, 233:674-688.
    • (2008) Exp Biol Med , vol.233 , pp. 674-688
    • Simopoulos, A.P.1
  • 3
    • 33646099323 scopus 로고    scopus 로고
    • Temporal changes in dietary fats: role of n-6 polyunsaturated fatty acids in excessive adipose tissue development and relationship to obesity
    • Ailhaud G., Massiera F., Weill P., Legrand P., Alessandri J.M., Guesnet P. Temporal changes in dietary fats: role of n-6 polyunsaturated fatty acids in excessive adipose tissue development and relationship to obesity. Prog Lipid Res 2006, 45:203-236.
    • (2006) Prog Lipid Res , vol.45 , pp. 203-236
    • Ailhaud, G.1    Massiera, F.2    Weill, P.3    Legrand, P.4    Alessandri, J.M.5    Guesnet, P.6
  • 4
    • 74949141013 scopus 로고    scopus 로고
    • Leptin receptor polymorphisms interact with polyunsaturated fatty acids to augment risk of insulin resistance and metabolic syndrome in adults
    • Phillips C.M., Goumidi L., Bertrais S., Field M.R., Ordovas J.M., Cupples L.A., et al. Leptin receptor polymorphisms interact with polyunsaturated fatty acids to augment risk of insulin resistance and metabolic syndrome in adults. J Nutr 2010, 140:238-244.
    • (2010) J Nutr , vol.140 , pp. 238-244
    • Phillips, C.M.1    Goumidi, L.2    Bertrais, S.3    Field, M.R.4    Ordovas, J.M.5    Cupples, L.A.6
  • 5
    • 36849077566 scopus 로고    scopus 로고
    • Treatment for 2 mo with n3 polyunsaturated fatty acids reduces adiposity and some atherogenic factors but does not improve insulin sensitivity in women with type 2 diabetes: a randomized controlled study
    • Kabir M., Skurnik G., Naour N., Pechtner V., Meugnier E., Rome S., et al. Treatment for 2 mo with n3 polyunsaturated fatty acids reduces adiposity and some atherogenic factors but does not improve insulin sensitivity in women with type 2 diabetes: a randomized controlled study. Am J Clin Nutr 2007, 86:1670-1679.
    • (2007) Am J Clin Nutr , vol.86 , pp. 1670-1679
    • Kabir, M.1    Skurnik, G.2    Naour, N.3    Pechtner, V.4    Meugnier, E.5    Rome, S.6
  • 6
    • 12544260664 scopus 로고    scopus 로고
    • Omega-3 PUFA of marine origin limit diet-induced obesity in mice by reducing cellularity of adipose tissue
    • Ruzickova J., Rossmeisl M., Prazak T., Flachs P., Sponarova J., Veck M., et al. Omega-3 PUFA of marine origin limit diet-induced obesity in mice by reducing cellularity of adipose tissue. Lipids 2004, 39:1177-1185.
    • (2004) Lipids , vol.39 , pp. 1177-1185
    • Ruzickova, J.1    Rossmeisl, M.2    Prazak, T.3    Flachs, P.4    Sponarova, J.5    Veck, M.6
  • 7
    • 77955502543 scopus 로고    scopus 로고
    • The role of inflammation and macrophage accumulation in the development of obesity-induced type 2 diabetes mellitus and the possible therapeutic effects of long-chain n-3 PUFA
    • Oliver E., McGillicuddy F., Phillips C., Toomey S., Roche H.M., et al. The role of inflammation and macrophage accumulation in the development of obesity-induced type 2 diabetes mellitus and the possible therapeutic effects of long-chain n-3 PUFA. Proc Nutr Soc 2010, 69:232-243.
    • (2010) Proc Nutr Soc , vol.69 , pp. 232-243
    • Oliver, E.1    McGillicuddy, F.2    Phillips, C.3    Toomey, S.4    Roche, H.M.5
  • 8
    • 0034809208 scopus 로고    scopus 로고
    • Polyunsaturated fatty acid-rich diets: effect on adipose tissue metabolism in rats
    • Gaíva M.H., Couto R.C., Oyama L.M., Couto G.E., Silveira V.L., Ribeiro E.B., et al. Polyunsaturated fatty acid-rich diets: effect on adipose tissue metabolism in rats. Br J Nutr 2001, 86:371-377.
    • (2001) Br J Nutr , vol.86 , pp. 371-377
    • Gaíva, M.H.1    Couto, R.C.2    Oyama, L.M.3    Couto, G.E.4    Silveira, V.L.5    Ribeiro, E.B.6
  • 9
    • 34047258183 scopus 로고    scopus 로고
    • Various dietary fats differentially change the gene expression of neuropeptides involved in body weight regulation in rats
    • Dziedzic B., Szemraj J., Bartkowiak J., Walczewska A. Various dietary fats differentially change the gene expression of neuropeptides involved in body weight regulation in rats. J Neuroendocrinol 2007, 19:364-373.
    • (2007) J Neuroendocrinol , vol.19 , pp. 364-373
    • Dziedzic, B.1    Szemraj, J.2    Bartkowiak, J.3    Walczewska, A.4
  • 10
    • 42249107130 scopus 로고    scopus 로고
    • Brain insulin, energy and glucose homeostasis; genes, environment and metabolic pathologies
    • Gerozissis K. Brain insulin, energy and glucose homeostasis; genes, environment and metabolic pathologies. Eur J Pharmacol 2008, 585:38-49.
    • (2008) Eur J Pharmacol , vol.585 , pp. 38-49
    • Gerozissis, K.1
  • 12
    • 69649095976 scopus 로고    scopus 로고
    • Studying the central control of food intake and obesity in rats
    • Ribeiro E.B. Studying the central control of food intake and obesity in rats. Rev Nutr 2009, 22(1):163-171.
    • (2009) Rev Nutr , vol.22 , Issue.1 , pp. 163-171
    • Ribeiro, E.B.1
  • 13
    • 67649428436 scopus 로고    scopus 로고
    • Hypothalamic serotonin in the control of food intake: physiological interactions and effect of obesity
    • Nova Science Publishers, New York, T.P. Starks (Ed.)
    • Ribeiro E.B., Telles M.M., Oyama L.M., Silveira V.L., Nascimento C.M.O. Hypothalamic serotonin in the control of food intake: physiological interactions and effect of obesity. Focus on Nutrition Research 2006, 121-148. Nova Science Publishers, New York. T.P. Starks (Ed.).
    • (2006) Focus on Nutrition Research , pp. 121-148
    • Ribeiro, E.B.1    Telles, M.M.2    Oyama, L.M.3    Silveira, V.L.4    Nascimento, C.M.O.5
  • 14
    • 0032828888 scopus 로고    scopus 로고
    • Influence of dietary fats on c-Fos-like immunoreactivity in mouse hypothalamus
    • Wang H., Storlien L.H., Huang X.F. Influence of dietary fats on c-Fos-like immunoreactivity in mouse hypothalamus. Brain Res 1999, 843:184-192.
    • (1999) Brain Res , vol.843 , pp. 184-192
    • Wang, H.1    Storlien, L.H.2    Huang, X.F.3
  • 15
    • 0036088134 scopus 로고    scopus 로고
    • Effects of dietary fat types on body fatness, leptin, and ARC leptin receptor, NPY, and AgRP mRNA expression
    • Wang H., Storlien L.H., Huang X.F. Effects of dietary fat types on body fatness, leptin, and ARC leptin receptor, NPY, and AgRP mRNA expression. Am J Physiol 2002, 282:E1352-E1359.
    • (2002) Am J Physiol , vol.282
    • Wang, H.1    Storlien, L.H.2    Huang, X.F.3
  • 16
    • 70849118314 scopus 로고    scopus 로고
    • Prolonged consumption of soy or fish-oil enriched diets differentially affects the pattern of hypothalamic neuronal activation induced by refeeding in rats
    • Watanabe R.L.H., Andrade I.S., Zemdegs J.C.S., Albuquerque1 K.T., Nascimento C.M.O., Oyama L.M., et al. Prolonged consumption of soy or fish-oil enriched diets differentially affects the pattern of hypothalamic neuronal activation induced by refeeding in rats. Nutr Neurosci 2009, 12:242-248.
    • (2009) Nutr Neurosci , vol.12 , pp. 242-248
    • Watanabe, R.L.H.1    Andrade, I.S.2    Zemdegs, J.C.S.3    Albuquerque, K.T.4    Nascimento, C.M.O.5    Oyama, L.M.6
  • 18
    • 33244464562 scopus 로고    scopus 로고
    • Critical nodes in signalling pathways: insights into insulin action
    • Taniguchi C.M., Emanuelli B., Kahn C.R. Critical nodes in signalling pathways: insights into insulin action. Nat Rev Mol Cell Biol 2006, 7:85-96.
    • (2006) Nat Rev Mol Cell Biol , vol.7 , pp. 85-96
    • Taniguchi, C.M.1    Emanuelli, B.2    Kahn, C.R.3
  • 20
    • 33745413014 scopus 로고    scopus 로고
    • Intake of trans fatty acid rich hydrogenated fat during pregnancy and lactation inhibits the hypophagic effect of central insulin in the adult offspring
    • Albuquerque K.T., Sardinha F.L., Telles M.M., Watanabe R.L., Nascimento C.M., Tavares do Carmo M.G., et al. Intake of trans fatty acid rich hydrogenated fat during pregnancy and lactation inhibits the hypophagic effect of central insulin in the adult offspring. Nutrition 2006, 22:820-829.
    • (2006) Nutrition , vol.22 , pp. 820-829
    • Albuquerque, K.T.1    Sardinha, F.L.2    Telles, M.M.3    Watanabe, R.L.4    Nascimento, C.M.5    Tavares do Carmo, M.G.6
  • 21
    • 33750631389 scopus 로고    scopus 로고
    • Gender difference in the effect of intrauterine malnutrition on the central anorexigenic action of insulin in adult rats
    • Sardinha F.L.C., Telles M.M., Albuquerque K.T., Oyama L.M., Guimarães P.A.M.P., Santos O.F.P., et al. Gender difference in the effect of intrauterine malnutrition on the central anorexigenic action of insulin in adult rats. Nutrition 2006, 22:1152-1161.
    • (2006) Nutrition , vol.22 , pp. 1152-1161
    • Sardinha, F.L.C.1    Telles, M.M.2    Albuquerque, K.T.3    Oyama, L.M.4    Guimarães, P.A.M.P.5    Santos, O.F.P.6
  • 22
    • 24944438230 scopus 로고    scopus 로고
    • Consumption of a fat-rich diet activates a proinflammatory response and induces insulin resistance in the hypothalamus
    • De Souza C.T., Araujo E.P., Bordin S., Ashimine R., Zollner R.L., Boschero A.C., et al. Consumption of a fat-rich diet activates a proinflammatory response and induces insulin resistance in the hypothalamus. Endocrinology 2005, 146:4192-4199.
    • (2005) Endocrinology , vol.146 , pp. 4192-4199
    • De Souza, C.T.1    Araujo, E.P.2    Bordin, S.3    Ashimine, R.4    Zollner, R.L.5    Boschero, A.C.6
  • 23
    • 52949096557 scopus 로고    scopus 로고
    • Hypothalamic IKKβ/NF-κB and ER stress link overnutrition to energy imbalance and obesity
    • Zhang X., Zhang G., Zhang H., Karin M., Bai H., Cai D. Hypothalamic IKKβ/NF-κB and ER stress link overnutrition to energy imbalance and obesity. Cell 2008, 135:61-73.
    • (2008) Cell , vol.135 , pp. 61-73
    • Zhang, X.1    Zhang, G.2    Zhang, H.3    Karin, M.4    Bai, H.5    Cai, D.6
  • 24
    • 66149118129 scopus 로고    scopus 로고
    • Hypothalamic proinflammatory lipid accumulation, inflammation, and insulin resistance in rats fed a high-fat diet
    • Posey K.A., Clegg D.J., Printz R.L., Byun J., Morton G.J., Vivekanandan-Giri A., et al. Hypothalamic proinflammatory lipid accumulation, inflammation, and insulin resistance in rats fed a high-fat diet. Am J Physiol Endocrinol Metab 2009, 296:1003-1012.
    • (2009) Am J Physiol Endocrinol Metab , vol.296 , pp. 1003-1012
    • Posey, K.A.1    Clegg, D.J.2    Printz, R.L.3    Byun, J.4    Morton, G.J.5    Vivekanandan-Giri, A.6
  • 25
    • 0015348189 scopus 로고
    • Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge
    • Friedewald T., Levy R.I., Frederickson D.S. Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin Chem 1972, 18:499-502.
    • (1972) Clin Chem , vol.18 , pp. 499-502
    • Friedewald, T.1    Levy, R.I.2    Frederickson, D.S.3
  • 26
    • 0021813187 scopus 로고
    • Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man
    • Matthews D.R., Hosker J.P., Rudenski A.S., Naylor B.A., Treacher D.F., Turner R.C. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 1985, 28:412-419.
    • (1985) Diabetologia , vol.28 , pp. 412-419
    • Matthews, D.R.1    Hosker, J.P.2    Rudenski, A.S.3    Naylor, B.A.4    Treacher, D.F.5    Turner, R.C.6
  • 28
    • 0016660889 scopus 로고
    • The cerebral ventricles as the avenue for the dipsogenic action of intracranial angiotensin
    • Johnson A.K., Epstein A.N. The cerebral ventricles as the avenue for the dipsogenic action of intracranial angiotensin. Brain Res 1975, 86:399-418.
    • (1975) Brain Res , vol.86 , pp. 399-418
    • Johnson, A.K.1    Epstein, A.N.2
  • 30
    • 33748423509 scopus 로고    scopus 로고
    • Distribution of insulin receptor substrate-2 in brain areas involved in energy homeostasis
    • Pardini A.W., Nguyen H.T., Figlewicz D.P., Baskin D.G., Williams D.L., Kim F., et al. Distribution of insulin receptor substrate-2 in brain areas involved in energy homeostasis. Brain Res 2006, 1112:169-178.
    • (2006) Brain Res , vol.1112 , pp. 169-178
    • Pardini, A.W.1    Nguyen, H.T.2    Figlewicz, D.P.3    Baskin, D.G.4    Williams, D.L.5    Kim, F.6
  • 31
    • 0032853976 scopus 로고    scopus 로고
    • Discrete expression of insulin receptor substrate-4 mRNA in adult rat brain
    • Numan S., Russell D.S. Discrete expression of insulin receptor substrate-4 mRNA in adult rat brain. Mol Brain Res 1999, 72:97-102.
    • (1999) Mol Brain Res , vol.72 , pp. 97-102
    • Numan, S.1    Russell, D.S.2
  • 32
    • 0033956283 scopus 로고    scopus 로고
    • Mice lacking insulin receptor substrate 4 exhibit mild defects in growth, reproduction, and glucose homeostasis
    • Fantin V.R., Wang Q., Lienhard G.E., Keller S.R. Mice lacking insulin receptor substrate 4 exhibit mild defects in growth, reproduction, and glucose homeostasis. Am J Physiol 2000, 278:127-133.
    • (2000) Am J Physiol , vol.278 , pp. 127-133
    • Fantin, V.R.1    Wang, Q.2    Lienhard, G.E.3    Keller, S.R.4
  • 33
    • 58549118766 scopus 로고    scopus 로고
    • Identification and characterization of an insulin receptor substrate 4-interacting protein in rat brain: implications for longevity
    • Chiba T., Inoue D., Mizuno A., Komatsu T., Fujita S., Kubota H., et al. Identification and characterization of an insulin receptor substrate 4-interacting protein in rat brain: implications for longevity. Neurobiol Aging 2009, 30:474-482.
    • (2009) Neurobiol Aging , vol.30 , pp. 474-482
    • Chiba, T.1    Inoue, D.2    Mizuno, A.3    Komatsu, T.4    Fujita, S.5    Kubota, H.6
  • 34
    • 16844370268 scopus 로고    scopus 로고
    • Regulation of insulin signalling by hyperinsulinaemia: role of IRS-1/2 serine phosphorylation and the mTOR/p70 S6K pathway
    • Ueno M., Carvalheira J.B.C., Tambascia R.C., Bezerra R.M.N., Amaral M.E., Carneiro E.M., et al. Regulation of insulin signalling by hyperinsulinaemia: role of IRS-1/2 serine phosphorylation and the mTOR/p70 S6K pathway. Diabetologia 2005, 48:506-518.
    • (2005) Diabetologia , vol.48 , pp. 506-518
    • Ueno, M.1    Carvalheira, J.B.C.2    Tambascia, R.C.3    Bezerra, R.M.N.4    Amaral, M.E.5    Carneiro, E.M.6
  • 35
    • 33644886769 scopus 로고    scopus 로고
    • Nutrients suppress phosphatidylinositol 3-Kinase/Akt signaling via raptor-dependent mTOR-mediated insulin receptor substrate 1 phosphorylation
    • Tzatsos A., Kandror K.V. Nutrients suppress phosphatidylinositol 3-Kinase/Akt signaling via raptor-dependent mTOR-mediated insulin receptor substrate 1 phosphorylation. Mol Cell Biol 2006, 26:63-76.
    • (2006) Mol Cell Biol , vol.26 , pp. 63-76
    • Tzatsos, A.1    Kandror, K.V.2
  • 36
    • 48749105887 scopus 로고    scopus 로고
    • Activation of hypothalamic S6 kinase mediates diet-induced hepatic insulin resistance in rats
    • Ono H., Pocai A., Wang Y., Sakoda H., Asano T., Backer J.M., et al. Activation of hypothalamic S6 kinase mediates diet-induced hepatic insulin resistance in rats. J Clin Invest 2008, 118:2959-2968.
    • (2008) J Clin Invest , vol.118 , pp. 2959-2968
    • Ono, H.1    Pocai, A.2    Wang, Y.3    Sakoda, H.4    Asano, T.5    Backer, J.M.6
  • 38
    • 72449128492 scopus 로고    scopus 로고
    • Hypothalamic inflammation and energy homeostasis: resolving the paradox
    • Thaler J.P., Choi S.J., Schwartz M.W., Wisse B.E. Hypothalamic inflammation and energy homeostasis: resolving the paradox. Front Neuroendocrinol 2010, 31:79-84.
    • (2010) Front Neuroendocrinol , vol.31 , pp. 79-84
    • Thaler, J.P.1    Choi, S.J.2    Schwartz, M.W.3    Wisse, B.E.4
  • 39
    • 84862324322 scopus 로고    scopus 로고
    • Long-term consumption of high-fat diets enriched with soy or fish oils affects hypothalamic insulin signaling in male rats (abstract)
    • Pimentel G.D., Dornellas A.P.S., Boldarine V.T., Rosa Neto J.C., Lira F.S., Cunha C.A., et al. Long-term consumption of high-fat diets enriched with soy or fish oils affects hypothalamic insulin signaling in male rats (abstract). Obesity Rev 2010, 11:152.
    • (2010) Obesity Rev , vol.11 , pp. 152
    • Pimentel, G.D.1    Dornellas, A.P.S.2    Boldarine, V.T.3    Rosa Neto, J.C.4    Lira, F.S.5    Cunha, C.A.6
  • 40
    • 1842484296 scopus 로고    scopus 로고
    • AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus
    • Minokoshi Y., Alquir T., Furukawa N., Kim Y.B., Lee A., Xue B., et al. AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus. Nature 2004, 428:569-574.
    • (2004) Nature , vol.428 , pp. 569-574
    • Minokoshi, Y.1    Alquir, T.2    Furukawa, N.3    Kim, Y.B.4    Lee, A.5    Xue, B.6
  • 41
    • 33745224043 scopus 로고    scopus 로고
    • Diet-induced obesity alters AMP kinase activity in hypothalamus and skeletal muscle
    • Martin T.L., Alquier T., Asakura K., Furukawa N., Preitner F., Kahn B.B. Diet-induced obesity alters AMP kinase activity in hypothalamus and skeletal muscle. J Biol Chem 2006, 281:18933-18941.
    • (2006) J Biol Chem , vol.281 , pp. 18933-18941
    • Martin, T.L.1    Alquier, T.2    Asakura, K.3    Furukawa, N.4    Preitner, F.5    Kahn, B.B.6
  • 42
    • 77955474312 scopus 로고    scopus 로고
    • Reduced fasting-induced activation of hypothalamic arcuate neurons is associated with hyperleptinemia and increased leptin sensitivity in obese mice
    • Becskei C., Lutz T.A., Riediger T. Reduced fasting-induced activation of hypothalamic arcuate neurons is associated with hyperleptinemia and increased leptin sensitivity in obese mice. Am J Physiol Regul Integr Comp Physiol 2010, 299:632-641.
    • (2010) Am J Physiol Regul Integr Comp Physiol , vol.299 , pp. 632-641
    • Becskei, C.1    Lutz, T.A.2    Riediger, T.3
  • 43
    • 77953351533 scopus 로고    scopus 로고
    • Associations between obesity and serum lipid-soluble micronutrients among premenopausal women
    • Chai W., Conroy S.M., Maskarinec G., Franke A.A., Pagano I.S., Cooney R.V. Associations between obesity and serum lipid-soluble micronutrients among premenopausal women. Nutr Res 2010, 30:227-232.
    • (2010) Nutr Res , vol.30 , pp. 227-232
    • Chai, W.1    Conroy, S.M.2    Maskarinec, G.3    Franke, A.A.4    Pagano, I.S.5    Cooney, R.V.6
  • 44
    • 0037228018 scopus 로고    scopus 로고
    • Interaction between leptin and insulin signaling pathways differentially affects JAK-STAT and PI 3-kinase-mediated signaling in rat liver
    • Carvalheira J.B.C., Ribeiro E.B., Folli F., Velloso L.A., Saad M.J.A. Interaction between leptin and insulin signaling pathways differentially affects JAK-STAT and PI 3-kinase-mediated signaling in rat liver. Biol Chem 2003, 384:151-159.
    • (2003) Biol Chem , vol.384 , pp. 151-159
    • Carvalheira, J.B.C.1    Ribeiro, E.B.2    Folli, F.3    Velloso, L.A.4    Saad, M.J.A.5
  • 45
    • 77950499307 scopus 로고    scopus 로고
    • Effects of atorvastatin and n-3 fatty acid supplementation on VLDL apolipoprotein C-III kinetics in men with abdominal obesity
    • Chan D.C., Nguyen M.N., Watts G.F., Ooi E.M., Barrett P.H. Effects of atorvastatin and n-3 fatty acid supplementation on VLDL apolipoprotein C-III kinetics in men with abdominal obesity. Am J Clin Nutr 2010, 91:900-906.
    • (2010) Am J Clin Nutr , vol.91 , pp. 900-906
    • Chan, D.C.1    Nguyen, M.N.2    Watts, G.F.3    Ooi, E.M.4    Barrett, P.H.5
  • 46
    • 73449142133 scopus 로고    scopus 로고
    • Dietary supplementation of n-3 PUFA reduces weight gain and improves postprandial lipaemia and the associated inflammatory response in the obese JCR:LA-cp rat
    • Hassanali Z., Ametaj B.N., Field C.J., Proctor S.D., Vine D.F. Dietary supplementation of n-3 PUFA reduces weight gain and improves postprandial lipaemia and the associated inflammatory response in the obese JCR:LA-cp rat. Diabetes Obes Metab 2010, 12:139-147.
    • (2010) Diabetes Obes Metab , vol.12 , pp. 139-147
    • Hassanali, Z.1    Ametaj, B.N.2    Field, C.J.3    Proctor, S.D.4    Vine, D.F.5
  • 48
    • 33748513253 scopus 로고    scopus 로고
    • Distinct regulation of IRS proteins in adipose tissue from obese aged and dexamethasone-treated rats
    • Caperuto L.C., Anhê G.F., Amanso A.M., Ribeiro L.M., Medina M.C., Souza L.C., et al. Distinct regulation of IRS proteins in adipose tissue from obese aged and dexamethasone-treated rats. Endocrine 2006, 29:391-398.
    • (2006) Endocrine , vol.29 , pp. 391-398
    • Caperuto, L.C.1    Anhê, G.F.2    Amanso, A.M.3    Ribeiro, L.M.4    Medina, M.C.5    Souza, L.C.6
  • 49
    • 77956165390 scopus 로고    scopus 로고
    • GPR120 is an omega-3 fatty acid receptor mediating potent anti-inflammatory and insulin-sensitizing effects
    • Oh D.Y., Talukdar S., Bae E.J., Imamura T., Morinaga H., Fan W.Q., et al. GPR120 is an omega-3 fatty acid receptor mediating potent anti-inflammatory and insulin-sensitizing effects. Cell 2010, 142:687-698.
    • (2010) Cell , vol.142 , pp. 687-698
    • Oh, D.Y.1    Talukdar, S.2    Bae, E.J.3    Imamura, T.4    Morinaga, H.5    Fan, W.Q.6


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