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Volumn 23, Issue 8, 2012, Pages 816-823

Inhibition of CD44 gene expression in human skin models, using self-delivery short interfering RNA administered by dissolvable microneedle arrays

Author keywords

[No Author keywords available]

Indexed keywords

HERMES ANTIGEN; MESSENGER RNA; SELF DELIVERY SMALL INTERFERING RNA; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

EID: 84862326954     PISSN: 10430342     EISSN: 15577422     Source Type: Journal    
DOI: 10.1089/hum.2011.211     Document Type: Article
Times cited : (39)

References (43)
  • 1
    • 0025282411 scopus 로고
    • CD44 is the principal cell surface receptor for hyaluronate
    • Aruffo, A., Stamenkovic, I., Melnick, M., et al. (1990). CD44 is the principal cell surface receptor for hyaluronate. Cell 61, 1303-1313.
    • (1990) Cell , vol.61 , pp. 1303-1313
    • Aruffo, A.1    Stamenkovic, I.2    Melnick, M.3
  • 2
    • 80052627990 scopus 로고    scopus 로고
    • Current progress of siRNA/shRNA therapeutics in clinical trials
    • Burnett, J.C., Rossi, J.J., and Tiemann, K. (2011). Current progress of siRNA/shRNA therapeutics in clinical trials. Bio-technol. J. 6, 1130-1146.
    • (2011) Bio-technol. J. , vol.6 , pp. 1130-1146
    • Burnett, J.C.1    Rossi, J.J.2    Tiemann, K.3
  • 3
    • 0035809198 scopus 로고    scopus 로고
    • An inducible mouse model for epidermolysis bullosa simplex: Implications for gene therapy
    • Cao, T., Longley, M.A., Wang, X.J., and Roop, D.R. (2001). An inducible mouse model for epidermolysis bullosa simplex: implications for gene therapy. J. Cell Biol. 152, 651-656.
    • (2001) J. Cell Biol. , vol.152 , pp. 651-656
    • Cao, T.1    Longley, M.A.2    Wang, X.J.3    Roop, D.R.4
  • 4
    • 32944461597 scopus 로고    scopus 로고
    • Mouse models in preclinical studies for pachyonychia congenita
    • Chen, J., and Roop, D.R. (2005). Mouse models in preclinical studies for pachyonychia congenita. J. Investig. Dermatol. Symp. Proc. 10, 37-46.
    • (2005) J. Investig. Dermatol. Symp. Proc. , vol.10 , pp. 37-46
    • Chen, J.1    Roop, D.R.2
  • 5
    • 78651314500 scopus 로고    scopus 로고
    • Potential clinical applications of siRNA technique: Benefits and limitations
    • Chen, S.H., and Zhaori, G. (2011). Potential clinical applications of siRNA technique: benefits and limitations. Eur. J. Clin. Invest. 41, 221-232.
    • (2011) Eur. J. Clin. Invest. , vol.41 , pp. 221-232
    • Chen, S.H.1    Zhaori, G.2
  • 6
    • 33845648163 scopus 로고    scopus 로고
    • Microneedles and other physical methods for overcoming the stratum corneum barrier for cutaneous gene therapy
    • Coulman, S., Allender, C., and Birchall, J. (2006). Microneedles and other physical methods for overcoming the stratum corneum barrier for cutaneous gene therapy. Crit. Rev. Ther. Drug Carrier Syst. 23, 205-258.
    • (2006) Crit. Rev. Ther. Drug Carrier Syst. , vol.23 , pp. 205-258
    • Coulman, S.1    Allender, C.2    Birchall, J.3
  • 7
    • 50149101511 scopus 로고    scopus 로고
    • Therapeutic RNAi targeting PCSK9 acutely lowers plasma cholesterol in rodents and LDL cholesterol in nonhuman primates
    • Frank-Kamenetsky, M., Grefhorst, A., Anderson, N.N., et al. (2008). Therapeutic RNAi targeting PCSK9 acutely lowers plasma cholesterol in rodents and LDL cholesterol in nonhuman primates. Proc. Natl. Acad. Sci. U.S.A. 105, 11915-11920.
    • (2008) Proc. Natl. Acad. Sci. U.S.A. , vol.105 , pp. 11915-11920
    • Frank-Kamenetsky, M.1    Grefhorst, A.2    Anderson, N.N.3
  • 9
    • 55249125056 scopus 로고    scopus 로고
    • Effect of microneedle design on pain in human volunteers
    • Gill, H.S., Denson, D.D., Burris, B.A., and Prausnitz, M.R. (2008). Effect of microneedle design on pain in human volunteers. Clin. J. Pain 24, 585-594.
    • (2008) Clin. J. Pain , vol.24 , pp. 585-594
    • Gill, H.S.1    Denson, D.D.2    Burris, B.A.3    Prausnitz, M.R.4
  • 10
    • 38349039515 scopus 로고    scopus 로고
    • In vivo reflectance-mode confocal microscopy in clinical dermatology and cosmetology
    • Gonzalez, S., and Gilaberte-Calzada, Y. (2008). In vivo reflectance-mode confocal microscopy in clinical dermatology and cosmetology. Int. J. Cosmet. Sci. 30, 1-17.
    • (2008) Int. J. Cosmet. Sci. , vol.30 , pp. 1-17
    • Gonzalez, S.1    Gilaberte-Calzada, Y.2
  • 11
    • 69249229546 scopus 로고    scopus 로고
    • SiRNA silencing of keratinocyte-specific GFP expression in a transgenic mouse skin model
    • Gonzalez-Gonzalez, E., Ra, H., Hickerson, R.P., et al. (2009). siRNA silencing of keratinocyte-specific GFP expression in a transgenic mouse skin model. Gene Ther. 16, 963-972.
    • (2009) Gene Ther , vol.16 , pp. 963-972
    • Gonzalez-Gonzalez, E.1    Ra, H.2    Hickerson, R.P.3
  • 12
    • 77956263271 scopus 로고    scopus 로고
    • Silencing of reporter gene expression in skin using siRNAs and expression of plasmid DNA delivered by a soluble protrusion array device (PAD)
    • Gonzalez-Gonzalez, E., Speaker, T.J., Hickerson, R.P., et al. (2010b). Silencing of reporter gene expression in skin using siRNAs and expression of plasmid DNA delivered by a soluble protrusion array device (PAD). Mol. Ther. 18, 1667-1674.
    • (2010) Mol. Ther. , vol.18 , pp. 1667-1674
    • Gonzalez-Gonzalez, E.1    Speaker, T.J.2    Hickerson, R.P.3
  • 13
    • 84859741493 scopus 로고    scopus 로고
    • Visualization of plasmid delivery to keratinocytes in mouse and human epidermis
    • Gonzalez-Gonzalez, E., Kim, Y.C., Speaker, T.J., et al. (2011). Visualization of plasmid delivery to keratinocytes in mouse and human epidermis. Sci. Rep. 1, 158.
    • (2011) Sci. Rep. , vol.1 , pp. 158
    • Gonzalez-Gonzalez, E.1    Kim, Y.C.2    Speaker, T.J.3
  • 14
    • 83655191975 scopus 로고    scopus 로고
    • Small interfering RNA targeting focal adhesion kinase prevents cardiac dysfunction in endotoxemia
    • Guido, M.C., Clemente, C.F., Moretti, A.I., et al. (2011). Small interfering RNA targeting focal adhesion kinase prevents cardiac dysfunction in endotoxemia. Shock 37, 77-84.
    • (2011) Shock , vol.37 , pp. 77-84
    • Guido, M.C.1    Clemente, C.F.2    Moretti, A.I.3
  • 15
    • 0026715219 scopus 로고
    • Identification and characterization of a cell surface proteoglycan on keratinocytes
    • Haggerty, J.G., Bretton, R.H., and Milstone, L.M. (1992). Identification and characterization of a cell surface proteoglycan on keratinocytes. J. Invest. Dermatol. 99, 374-380.
    • (1992) J. Invest. Dermatol. , vol.99 , pp. 374-380
    • Haggerty, J.G.1    Bretton, R.H.2    Milstone, L.M.3
  • 16
    • 39149111247 scopus 로고    scopus 로고
    • Single-nucleotide specific siRNA targeting in a dominant-negative skin model
    • Hickerson, R.P., Smith, F.J., Reeves, R.E., et al. (2008). Single-nucleotide specific siRNA targeting in a dominant-negative skin model. J. Invest. Dermatol. 128, 594-605.
    • (2008) J. Invest. Dermatol. , vol.128 , pp. 594-605
    • Hickerson, R.P.1    Smith, F.J.2    Reeves, R.E.3
  • 17
    • 79954976090 scopus 로고    scopus 로고
    • Use of self-delivery siRNAs to inhibit gene expression in an organotypic pachyonychia congenita model
    • Hickerson, R.P., Flores, M.A., Leake, D., et al. (2011a). Use of self-delivery siRNAs to inhibit gene expression in an organotypic pachyonychia congenita model. J. Invest. Dermatol. 131, 1037-1044.
    • (2011) J. Invest. Dermatol. , vol.131 , pp. 1037-1044
    • Hickerson, R.P.1    Flores, M.A.2    Leake, D.3
  • 18
    • 79954616664 scopus 로고    scopus 로고
    • Development of quantitative molecular clinical end points for siRNA clinical trials
    • Hickerson, R.P., Leachman, S.A., Pho, L.N., et al. (2011b). Development of quantitative molecular clinical end points for siRNA clinical trials. J. Invest. Dermatol. 131, 1029-1036.
    • (2011) J. Invest. Dermatol. , vol.131 , pp. 1029-1036
    • Hickerson, R.P.1    Leachman, S.A.2    Pho, L.N.3
  • 19
    • 80053156423 scopus 로고    scopus 로고
    • Delivery of siRNA and other macromolecules into skin and cells using a peptide enhancer
    • Hsu, T., and Mitragotri, S. (2011). Delivery of siRNA and other macromolecules into skin and cells using a peptide enhancer. Proc. Natl. Acad. Sci. U.S.A. 108, 15816-15821.
    • (2011) Proc. Natl. Acad. Sci. U.S.A. , vol.108 , pp. 15816-15821
    • Hsu, T.1    Mitragotri, S.2
  • 20
    • 80052997997 scopus 로고    scopus 로고
    • SiRNA targeting EGFR effectively prevents posterior capsular opacification after cataract surgery
    • Huang, W.R., Fan, X.X., and Tang, X. (2011). SiRNA targeting EGFR effectively prevents posterior capsular opacification after cataract surgery. Mol. Vis. 17, 2349-2355.
    • (2011) Mol. Vis. , vol.17 , pp. 2349-2355
    • Huang, W.R.1    Fan, X.X.2    Tang, X.3
  • 21
    • 70349755570 scopus 로고    scopus 로고
    • Achieving successful delivery of nucleic acids to skin: 6th Annual Meeting of the International Pachyonychia Congenita Consortium
    • Kaspar, R.L., McLean, W.H., and Schwartz, M.E. (2009). Achieving successful delivery of nucleic acids to skin: 6th Annual Meeting of the International Pachyonychia Congenita Consortium. J. Invest. Dermatol. 129, 2085-2087.
    • (2009) J. Invest. Dermatol. , vol.129 , pp. 2085-2087
    • Kaspar, R.L.1    McLean, W.H.2    Schwartz, M.E.3
  • 22
    • 79954599490 scopus 로고    scopus 로고
    • Toward a treatment for pachyonychia congenita: Report on the 7th Annual International Pachyonychia Con-genita Consortium meeting
    • Kaspar, R.L., Leachman, S.A., McLean, W.H., and Schwartz, M.E. (2011). Toward a treatment for pachyonychia congenita: Report on the 7th Annual International Pachyonychia Con-genita Consortium meeting. J. Invest. Dermatol. 131, 1011-1014.
    • (2011) J. Invest. Dermatol. , vol.131 , pp. 1011-1014
    • Kaspar, R.L.1    Leachman, S.A.2    McLean, W.H.3    Schwartz, M.E.4
  • 23
    • 0036308695 scopus 로고    scopus 로고
    • Cutaneous gene transfer for skin and systemic diseases
    • Khavari, P.A., Rollman, O., and Vahlquist, A. (2002). Cutaneous gene transfer for skin and systemic diseases. J. Intern. Med. 252, 1-10.
    • (2002) J. Intern. Med. , vol.252 , pp. 1-10
    • Khavari, P.A.1    Rollman, O.2    Vahlquist, A.3
  • 24
    • 0027012889 scopus 로고
    • The core protein of epican, a heparan sulfate proteoglycan on keratinocytes, is an alternative form of CD44
    • Kugelman, L.C., Ganguly, S., Haggerty, J.G., et al. (1992). The core protein of epican, a heparan sulfate proteoglycan on keratinocytes, is an alternative form of CD44. J. Invest. Der-matol. 99, 886-891.
    • (1992) J. Invest. Der-matol. , vol.99 , pp. 886-891
    • Kugelman, L.C.1    Ganguly, S.2    Haggerty, J.G.3
  • 25
    • 82955250900 scopus 로고    scopus 로고
    • Efficient in vivo delivery of siRNA into brain capillary endothelial cells along with endogenous lipoprotein
    • Kuwahara, H., Nishina, K., Yoshida, K., et al. (2011). Efficient in vivo delivery of siRNA into brain capillary endothelial cells along with endogenous lipoprotein. Mol. Ther. 19, 2213-2221.
    • (2011) Mol. Ther. , vol.19 , pp. 2213-2221
    • Kuwahara, H.1    Nishina, K.2    Yoshida, K.3
  • 26
    • 48049103228 scopus 로고    scopus 로고
    • Therapeutic siRNAs for dominant genetic skin disorders including pachyonychia congenita
    • Leachman, S.A., Hickerson, R.P., Hull, P.R., et al. (2008). Therapeutic siRNAs for dominant genetic skin disorders including pachyonychia congenita. J. Dermatol. Sci. 51, 151-157.
    • (2008) J. Dermatol. Sci. , vol.51 , pp. 151-157
    • Leachman, S.A.1    Hickerson, R.P.2    Hull, P.R.3
  • 27
    • 76349084709 scopus 로고    scopus 로고
    • First-in-human mutation-targeted siRNA phase Ib trial of an inherited skin disorder
    • Leachman, S.A., Hickerson, R.P., Schwartz, M.E., et al. (2010). First-in-human mutation-targeted siRNA phase Ib trial of an inherited skin disorder. Mol. Ther. 18, 442-446.
    • (2010) Mol. Ther. , vol.18 , pp. 442-446
    • Leachman, S.A.1    Hickerson, R.P.2    Schwartz, M.E.3
  • 28
    • 84861184577 scopus 로고    scopus 로고
    • Generic and personalized RNAi therapeutics for a dominant-negative epidermal fragility disorder
    • in press
    • Leslie Pedrioli, D.M., Fu, D.J., Gonzalez-Gonzalez, E., et al. (2012). Generic and personalized RNAi therapeutics for a dominant-negative epidermal fragility disorder. J. Invest. Dermatol. (in press).
    • (2012) J. Invest. Dermatol.
    • Leslie Pedrioli, D.M.1    Fu, D.J.2    Gonzalez-Gonzalez, E.3
  • 29
    • 83155181586 scopus 로고    scopus 로고
    • Keratin disorders: From gene to therapy
    • McLean, W.H., and Moore, C.B. (2011). Keratin disorders: From gene to therapy. Hum. Mol. Genet. 20, R189-R197.
    • (2011) Hum. Mol. Genet. , vol.20
    • McLean, W.H.1    Moore, C.B.2
  • 30
    • 0030966842 scopus 로고    scopus 로고
    • CD44: Structure, function, and association with the malignant process
    • Naor, D., Sionov, R.V., and Ish-Shalom, D. (1997). CD44: Structure, function, and association with the malignant process. Adv. Cancer Res. 71, 241-319.
    • (1997) Adv. Cancer Res. , vol.71 , pp. 241-319
    • Naor, D.1    Sionov, R.V.2    Ish-Shalom, D.3
  • 33
    • 1242308254 scopus 로고    scopus 로고
    • Current status and future potential of transdermal drug delivery
    • Prausnit, M.R., Mitragotri, S., and Langer, R. (2004). Current status and future potential of transdermal drug delivery. Nat. Rev. Drug Discov. 3, 115-124.
    • (2004) Nat. Rev. Drug Discov. , vol.3 , pp. 115-124
    • Prausnit, M.R.1    Mitragotri, S.2    Langer, R.3
  • 34
    • 79954586044 scopus 로고    scopus 로고
    • In vivo imaging of human and mouse skin with a handheld dual-axis confocal fluorescence microscope
    • Ra, H., Piyawattanametha, W., Gonzalez-Gonzalez, E., et al. (2011). In vivo imaging of human and mouse skin with a handheld dual-axis confocal fluorescence microscope. J. Invest. Dermatol. 131, 1061-1066.
    • (2011) J. Invest. Dermatol. , vol.131 , pp. 1061-1066
    • Ra, H.1    Piyawattanametha, W.2    Gonzalez-Gonzalez, E.3
  • 35
    • 68149173150 scopus 로고    scopus 로고
    • Phase I/II clinical evaluation of StrataGraft: A consistent, pathogen-free human skin substitute
    • discussion 873-874
    • Schurr, M.J., Foster, K.N., Centanni, J.M., et al. (2009). Phase I/II clinical evaluation of StrataGraft: A consistent, pathogen-free human skin substitute. J. Trauma 66, 866-873; discussion 873-874.
    • (2009) J. Trauma , vol.66 , pp. 866-873
    • Schurr, M.J.1    Foster, K.N.2    Centanni, J.M.3
  • 36
    • 0027065573 scopus 로고
    • Genomic structure of DNA encoding the lymphocyte homing receptor CD44 reveals at least 12 alternatively spliced exons
    • Screaton, G.R., Bell, M.V., Jackson, D.G., et al. (1992). Genomic structure of DNA encoding the lymphocyte homing receptor CD44 reveals at least 12 alternatively spliced exons. Proc. Natl. Acad. Sci. U.S.A. 89, 12160-12164.
    • (1992) Proc. Natl. Acad. Sci. U.S.A. , vol.89 , pp. 12160-12164
    • Screaton, G.R.1    Bell, M.V.2    Jackson, D.G.3
  • 37
    • 78449309070 scopus 로고    scopus 로고
    • Efficient and targeted delivery of siRNA in vivo
    • Shim, M.S., and Kwon, Y.J. (2010). Efficient and targeted delivery of siRNA in vivo. FEBS J. 277, 4814-4827.
    • (2010) FEBS J. , vol.277 , pp. 4814-4827
    • Shim, M.S.1    Kwon, Y.J.2
  • 38
    • 79956022523 scopus 로고    scopus 로고
    • SiRNA-induced liver ApoB knockdown lowers serum LDL-cholesterol in a mouse model with human-like serum lipids
    • Tadin-Strapps, M., Peterson, L.B., Cumiskey, A.M., et al. (2011). siRNA-induced liver ApoB knockdown lowers serum LDL-cholesterol in a mouse model with human-like serum lipids. J. Lipid Res. 52, 1084-1097.
    • (2011) J. Lipid Res. , vol.52 , pp. 1084-1097
    • Tadin-Strapps, M.1    Peterson, L.B.2    Cumiskey, A.M.3
  • 39
  • 40
    • 0026706103 scopus 로고
    • Distribution of hyaluronan and its CD44 receptor in the epithelia of human skin appendages
    • Wang, C., Tammi, M., and Tammi, R. (1992). Distribution of hyaluronan and its CD44 receptor in the epithelia of human skin appendages. Histochemistry 98, 105-112.
    • (1992) Histochemistry , vol.98 , pp. 105-112
    • Wang, C.1    Tammi, M.2    Tammi, R.3
  • 41
    • 0028957613 scopus 로고
    • CD44 expression in normal human skin and skin tumors
    • Yasaka, N., Furue, M., and Tamaki, K. (1995). CD44 expression in normal human skin and skin tumors. J. Dermatol. 22, 88-94.
    • (1995) J. Dermatol. , vol.22 , pp. 88-94
    • Yasaka, N.1    Furue, M.2    Tamaki, K.3
  • 42
    • 0032926881 scopus 로고    scopus 로고
    • Growth and differentiation regulate CD44 expression on human keratino-cytes
    • Zhou, J., Haggerty, J.G., and Milstone, L.M. (1999). Growth and differentiation regulate CD44 expression on human keratino-cytes. In Vitro Cell Dev. Biol. Anim. 35, 228-235.
    • (1999) In Vitro Cell Dev. Biol. Anim. , vol.35 , pp. 228-235
    • Zhou, J.1    Haggerty, J.G.2    Milstone, L.M.3
  • 43
    • 33646185371 scopus 로고    scopus 로고
    • RNAi-mediated gene silencing in non-human primates
    • Zimmermann, T.S., Lee, A.C., Akinc, A., et al. (2006). RNAi-mediated gene silencing in non-human primates. Nature 441, 111-114.
    • (2006) Nature , vol.441 , pp. 111-114
    • Zimmermann, T.S.1    Lee, A.C.2    Akinc, A.3


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