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Volumn 128, Issue 3, 2008, Pages 594-605

Single-nucleotide-specific siRNA targeting in a dominant-negative skin model

Author keywords

[No Author keywords available]

Indexed keywords

ENHANCED GREEN FLUORESCENT PROTEIN; FIREFLY LUCIFERASE; NUCLEOTIDE; SMALL INTERFERING RNA;

EID: 39149111247     PISSN: 0022202X     EISSN: 15231747     Source Type: Journal    
DOI: 10.1038/sj.jid.5701060     Document Type: Article
Times cited : (103)

References (54)
  • 1
    • 0026345962 scopus 로고
    • Epidermolysis bullosa simplex: Evidence in two families for keratin gene abnormalities
    • Bonifas JM, Rothman AL, Epstein EH Jr (1991) Epidermolysis bullosa simplex: evidence in two families for keratin gene abnormalities. Science 254:1202-5
    • (1991) Science , vol.254 , pp. 1202-1205
    • Bonifas, J.M.1    Rothman, A.L.2    Epstein Jr, E.H.3
  • 4
    • 0036726313 scopus 로고    scopus 로고
    • Stable suppression of tumorigenicity by virus-mediated RNA interference
    • Brummelkamp TR, Bernards R, Agami R (2002) Stable suppression of tumorigenicity by virus-mediated RNA interference. Cancer Cell 2: 243-7
    • (2002) Cancer Cell , vol.2 , pp. 243-247
    • Brummelkamp, T.R.1    Bernards, R.2    Agami, R.3
  • 5
    • 0035809198 scopus 로고    scopus 로고
    • An inducible mouse model for epidermolysis bullosa simplex: Implications for gene therapy
    • Cao T, Longley MA, Wang XJ, Roop DR (2001) An inducible mouse model for epidermolysis bullosa simplex: implications for gene therapy. J Cell Biol 152:651-6
    • (2001) J Cell Biol , vol.152 , pp. 651-656
    • Cao, T.1    Longley, M.A.2    Wang, X.J.3    Roop, D.R.4
  • 6
    • 22144494662 scopus 로고    scopus 로고
    • Molecular imaging using labeled donor tissues reveals patterns of engraftment, rejection, and survival in transplantation
    • Cao YA, Bachmann MH, Beilhack A, Yang Y, Tanaka M, Swijnenburg RJ et al. (2005a) Molecular imaging using labeled donor tissues reveals patterns of engraftment, rejection, and survival in transplantation. Transplantation 80:134-9
    • (2005) Transplantation , vol.80 , pp. 134-139
    • Cao, Y.A.1    Bachmann, M.H.2    Beilhack, A.3    Yang, Y.4    Tanaka, M.5    Swijnenburg, R.J.6
  • 7
    • 22144494662 scopus 로고    scopus 로고
    • Molecular imaging using labeled donor tissues reveals patterns of engraftment, rejection, and survival in transplantation
    • Cao YA, Bachmann MH, Beilhack A, Yang Y, Tanaka M, Swijnenburg RJ et al. (2005b) Molecular imaging using labeled donor tissues reveals patterns of engraftment, rejection, and survival in transplantation. Transplantation 80:134-9
    • (2005) Transplantation , vol.80 , pp. 134-139
    • Cao, Y.A.1    Bachmann, M.H.2    Beilhack, A.3    Yang, Y.4    Tanaka, M.5    Swijnenburg, R.J.6
  • 8
    • 0041331496 scopus 로고    scopus 로고
    • siRNA function in RNAi: A chemical modification analysis
    • Chiu YL, Rana TM (2003) siRNA function in RNAi: a chemical modification analysis. RNA 9:1034-48
    • (2003) RNA , vol.9 , pp. 1034-1048
    • Chiu, Y.L.1    Rana, T.M.2
  • 9
    • 0025861772 scopus 로고
    • Point mutations in human keratin 14 genes of epidermolysis bullosa simplex patients: Genetic and functional analyses
    • Coulombe PA, Hutton ME, Letai A, Hebert A, Paller AS, Fuchs E (1991) Point mutations in human keratin 14 genes of epidermolysis bullosa simplex patients: genetic and functional analyses. Cell 66: 1301-11
    • (1991) Cell , vol.66 , pp. 1301-1311
    • Coulombe, P.A.1    Hutton, M.E.2    Letai, A.3    Hebert, A.4    Paller, A.S.5    Fuchs, E.6
  • 10
    • 0038606999 scopus 로고    scopus 로고
    • Structural variations and stabilising modifications of synthetic siRNAs in mammalian cells
    • Czauderna F, Fechtner M, Dames S, Aygun H, Klippel A, Pronk GJ et al. (2003) Structural variations and stabilising modifications of synthetic siRNAs in mammalian cells. Nucleic Acids Res 31:2705-16
    • (2003) Nucleic Acids Res , vol.31 , pp. 2705-2716
    • Czauderna, F.1    Fechtner, M.2    Dames, S.3    Aygun, H.4    Klippel, A.5    Pronk, G.J.6
  • 12
    • 0242379146 scopus 로고    scopus 로고
    • Selective silencing by RNAi of a dominant allele that causes amyotrophic lateral sclerosis
    • Ding H, Schwarz DS, Keene A, Affar el B, Fenton L, Xia X et al. (2003) Selective silencing by RNAi of a dominant allele that causes amyotrophic lateral sclerosis. Aging Cell 2:209-17
    • (2003) Aging Cell , vol.2 , pp. 209-217
    • Ding, H.1    Schwarz, D.S.2    Keene, A.3    Affar el, B.4    Fenton, L.5    Xia, X.6
  • 13
    • 0035015174 scopus 로고    scopus 로고
    • Analysis of the aphthovirus 2A/2B polyprotein 'cleavage' mechanism indicates not a proteolytic reaction, but a novel translational effect: A putative ribosomal 'skip'
    • Donnelly ML, Luke G, Mehrotra A, Li X, Hughes LE, Gani D et al. (2001) Analysis of the aphthovirus 2A/2B polyprotein 'cleavage' mechanism indicates not a proteolytic reaction, but a novel translational effect: a putative ribosomal 'skip'. J Gen Virol 82:1013-25
    • (2001) J Gen Virol , vol.82 , pp. 1013-1025
    • Donnelly, M.L.1    Luke, G.2    Mehrotra, A.3    Li, X.4    Hughes, L.E.5    Gani, D.6
  • 14
    • 15044358407 scopus 로고    scopus 로고
    • A systematic analysis of the silencing effects of an active siRNA at all single-nucleotide mismatched target sites
    • Du Q, Thonberg H, Wang J, Wahlestedt C, Liang Z (2005) A systematic analysis of the silencing effects of an active siRNA at all single-nucleotide mismatched target sites. Nucleic Acids Res 33:1671-7
    • (2005) Nucleic Acids Res , vol.33 , pp. 1671-1677
    • Du, Q.1    Thonberg, H.2    Wang, J.3    Wahlestedt, C.4    Liang, Z.5
  • 15
    • 33746228119 scopus 로고    scopus 로고
    • Knocking down disease with siRNAs
    • Dykxhoorn DM, Lieberman J (2006) Knocking down disease with siRNAs. Cell 126:231-5
    • (2006) Cell , vol.126 , pp. 231-235
    • Dykxhoorn, D.M.1    Lieberman, J.2
  • 16
    • 33645148088 scopus 로고    scopus 로고
    • The silent treatment: SiRNAs as small molecule drugs
    • Dykxhoorn DM, Palliser D, Lieberman J (2006a) The silent treatment: siRNAs as small molecule drugs. Gene Therapy 13:541-52
    • (2006) Gene Therapy , vol.13 , pp. 541-552
    • Dykxhoorn, D.M.1    Palliser, D.2    Lieberman, J.3
  • 17
    • 33645826719 scopus 로고    scopus 로고
    • Determinants of specific RNA interference-mediated silencing of human betaglobin alleles differing by a single nucleotide polymorphism
    • Dykxhoorn DM, Schlehuber LD, London IM, Lieberman J (2006b) Determinants of specific RNA interference-mediated silencing of human betaglobin alleles differing by a single nucleotide polymorphism. Proc Natl Acad Sci USA 103:5953-8
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 5953-5958
    • Dykxhoorn, D.M.1    Schlehuber, L.D.2    London, I.M.3    Lieberman, J.4
  • 18
    • 0035803583 scopus 로고    scopus 로고
    • Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysate
    • Elbashir SM, Martinez J, Patkaniowska A, Lendeckel W, Tuschl T (2001) Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysate. EMBO J 20:6877-88
    • (2001) EMBO J , vol.20 , pp. 6877-6888
    • Elbashir, S.M.1    Martinez, J.2    Patkaniowska, A.3    Lendeckel, W.4    Tuschl, T.5
  • 20
    • 33750616005 scopus 로고    scopus 로고
    • Gene therapy progress and prospects: The skin - easily accessible, but still far away
    • Hengge UR (2006) Gene therapy progress and prospects: the skin - easily accessible, but still far away. Gene Therapy 13:1555-63
    • (2006) Gene Therapy , vol.13 , pp. 1555-1563
    • Hengge, U.R.1
  • 21
    • 0029053818 scopus 로고
    • Cytokine gene expression in epidermis with biological effects following injection of naked DNA
    • Hengge UR, Chan EF, Foster RA, Walker PS, Vogel JC (1995) Cytokine gene expression in epidermis with biological effects following injection of naked DNA. Nat Genet 10:161-6
    • (1995) Nat Genet , vol.10 , pp. 161-166
    • Hengge, U.R.1    Chan, E.F.2    Foster, R.A.3    Walker, P.S.4    Vogel, J.C.5
  • 22
    • 0029993919 scopus 로고    scopus 로고
    • Expression of naked DNA in human, pig, and mouse skin
    • Hengge UR, Walker PS, Vogel JC (1996) Expression of naked DNA in human, pig, and mouse skin. J Clin Invest 97:2911-6
    • (1996) J Clin Invest , vol.97 , pp. 2911-2916
    • Hengge, U.R.1    Walker, P.S.2    Vogel, J.C.3
  • 23
    • 0032965997 scopus 로고    scopus 로고
    • Human keratin diseases: The increasing spectrum of disease and subtlety of the phenotype-genotype correlation
    • Irvine AD, McLean WHI (1999) Human keratin diseases: the increasing spectrum of disease and subtlety of the phenotype-genotype correlation. Br J Dermatol 140:815-28
    • (1999) Br J Dermatol , vol.140 , pp. 815-828
    • Irvine, A.D.1    McLean, W.H.I.2
  • 24
    • 0036308695 scopus 로고    scopus 로고
    • Cutaneous gene transfer for skin and systemic diseases
    • Khavari PA, Rollman O, Vahlquist A (2002) Cutaneous gene transfer for skin and systemic diseases. J Intern Med 252:1-10
    • (2002) J Intern Med , vol.252 , pp. 1-10
    • Khavari, P.A.1    Rollman, O.2    Vahlquist, A.3
  • 26
    • 0026545645 scopus 로고
    • A mutation in the conserved helix termination peptide of keratin 5 in hereditary skin blistering
    • Lane EB, Rugg EL, Navsaria H, Leigh IM, Heagerty AH, Ishida-Yamamoto A., et al. (1992) A mutation in the conserved helix termination peptide of keratin 5 in hereditary skin blistering. Nature 356:244-6
    • (1992) Nature , vol.356 , pp. 244-246
    • Lane, E.B.1    Rugg, E.L.2    Navsaria, H.3    Leigh, I.M.4    Heagerty, A.H.5    Ishida-Yamamoto, A.6
  • 30
    • 0032903219 scopus 로고    scopus 로고
    • Identification of sporadic mutations in the helix initiation motif of keratin 6 in two pachyonychia congenita patients: Further evidence for a mutational hot spot
    • Lin MT, Levy ML, Bowden PE, Magro C, Baden L, Baden HP et al. (1999) Identification of sporadic mutations in the helix initiation motif of keratin 6 in two pachyonychia congenita patients: further evidence for a mutational hot spot. Exp Dermatol 8:115-9
    • (1999) Exp Dermatol , vol.8 , pp. 115-119
    • Lin, M.T.1    Levy, M.L.2    Bowden, P.E.3    Magro, C.4    Baden, L.5    Baden, H.P.6
  • 33
    • 32944463063 scopus 로고    scopus 로고
    • Insights into genotype-phenotype correlation in pachyonychia congenita from the human intermediate filament mutation database
    • McLean WHI, Smith FJD, Cassidy AJ (2005) Insights into genotype-phenotype correlation in pachyonychia congenita from the human intermediate filament mutation database. J Investig Dermatol Symp Proc 10:31-6
    • (2005) J Investig Dermatol Symp Proc , vol.10 , pp. 31-36
    • McLean, W.H.I.1    Smith, F.J.D.2    Cassidy, A.J.3
  • 35
    • 20044396377 scopus 로고    scopus 로고
    • Activity of stabilized short interfering RNA in a mouse model of hepatitis B virus replication
    • Morrissey DV, Blanchard K, Shaw L, Jensen K, Lockridge JA, Dickinson B et al. (2005) Activity of stabilized short interfering RNA in a mouse model of hepatitis B virus replication. Hepatology 41:1349-56
    • (2005) Hepatology , vol.41 , pp. 1349-1356
    • Morrissey, D.V.1    Blanchard, K.2    Shaw, L.3    Jensen, K.4    Lockridge, J.A.5    Dickinson, B.6
  • 36
    • 6344273968 scopus 로고    scopus 로고
    • Intermediate filament proteins and their associated diseases
    • Omary MB, Coulombe PA, McLean WH (2004) Intermediate filament proteins and their associated diseases. N Engl J Med 351:2087-100
    • (2004) N Engl J Med , vol.351 , pp. 2087-2100
    • Omary, M.B.1    Coulombe, P.A.2    McLean, W.H.3
  • 37
    • 0035503934 scopus 로고    scopus 로고
    • Reduction in dermal fibrosis in the tight-skin (Tsk) mouse after local application of halofuginone
    • Pines M, Domb A, Ohana M, Inbar J, Genina O, Alexiev R et al. (2001) Reduction in dermal fibrosis in the tight-skin (Tsk) mouse after local application of halofuginone. Biochem Pharmacol 62:1221-7
    • (2001) Biochem Pharmacol , vol.62 , pp. 1221-1227
    • Pines, M.1    Domb, A.2    Ohana, M.3    Inbar, J.4    Genina, O.5    Alexiev, R.6
  • 38
    • 33646201069 scopus 로고    scopus 로고
    • Electroporation-enhanced nonviral gene transfer for the prevention or treatment of immunological, endocrine and neoplastic diseases
    • Prud'homme GJ, Glinka Y, Khan AS, Draghia-Akli R (2006) Electroporation-enhanced nonviral gene transfer for the prevention or treatment of immunological, endocrine and neoplastic diseases. Curr Gene Ther 6:243-73
    • (2006) Curr Gene Ther , vol.6 , pp. 243-273
    • Prud'homme, G.J.1    Glinka, Y.2    Khan, A.S.3    Draghia-Akli, R.4
  • 39
    • 0036413572 scopus 로고    scopus 로고
    • Direct injection of naked DNA and cytokine transgene expression: Implications for keratinocyte gene therapy
    • Sawamura D, Akiyama M, Shimizu H (2002) Direct injection of naked DNA and cytokine transgene expression: implications for keratinocyte gene therapy. Clin Exp Dermatol 27:480-4
    • (2002) Clin Exp Dermatol , vol.27 , pp. 480-484
    • Sawamura, D.1    Akiyama, M.2    Shimizu, H.3
  • 41
    • 11144267737 scopus 로고    scopus 로고
    • Improved monomeric red, orange and yellow fluorescent proteins derived from Discosoma sp. red fluorescent protein
    • Shaner NC, Campbell RE, Steinbach PA, Giepmans BN, Palmer AE, Tsien RY (2004) Improved monomeric red, orange and yellow fluorescent proteins derived from Discosoma sp. red fluorescent protein. Nat Biotechnol 22:1567-72
    • (2004) Nat Biotechnol , vol.22 , pp. 1567-1572
    • Shaner, N.C.1    Campbell, R.E.2    Steinbach, P.A.3    Giepmans, B.N.4    Palmer, A.E.5    Tsien, R.Y.6
  • 43
    • 0038326541 scopus 로고    scopus 로고
    • The molecular genetics of keratin disorders
    • Smith F (2003) The molecular genetics of keratin disorders. Am J Clin Dermatol 4:347-64
    • (2003) Am J Clin Dermatol , vol.4 , pp. 347-364
    • Smith, F.1
  • 46
    • 0344286480 scopus 로고    scopus 로고
    • A mutation detection strategy for the human keratin 6A gene and novel missense mutations in two cases of pachyonychia congenita type 1
    • Smith FJD, McKenna KE, Irvine AD, Bingham EA, Coleman CM, Uitto J et al. (1999) A mutation detection strategy for the human keratin 6A gene and novel missense mutations in two cases of pachyonychia congenita type 1. Exp Dermatol 8:109-14
    • (1999) Exp Dermatol , vol.8 , pp. 109-114
    • Smith, F.J.D.1    McKenna, K.E.2    Irvine, A.D.3    Bingham, E.A.4    Coleman, C.M.5    Uitto, J.6
  • 47
    • 0037348329 scopus 로고    scopus 로고
    • RNA interference targeting Fas protects mice from fulminant hepatitis
    • Song E, Lee SK, Wang J, Ince N, Ouyang N, Min J et al. (2003) RNA interference targeting Fas protects mice from fulminant hepatitis. Nat Med 9:347-51
    • (2003) Nat Med , vol.9 , pp. 347-351
    • Song, E.1    Lee, S.K.2    Wang, J.3    Ince, N.4    Ouyang, N.5    Min, J.6
  • 48
    • 9144247189 scopus 로고    scopus 로고
    • Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs
    • Soutschek J, Akinc A, Bramlage B, Charisse K, Constien R, Donoghue M et al. (2004) Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs. Nature 432:173-8
    • (2004) Nature , vol.432 , pp. 173-178
    • Soutschek, J.1    Akinc, A.2    Bramlage, B.3    Charisse, K.4    Constien, R.5    Donoghue, M.6
  • 49
    • 0027730471 scopus 로고
    • Concurrence between the molecular overlap regions in keratin intermediate filaments and the locations of keratin mutations in genodermatoses
    • Steinert PM, Yang JM, Bale SJ, Compton JG (1993) Concurrence between the molecular overlap regions in keratin intermediate filaments and the locations of keratin mutations in genodermatoses. Biochem Biophyl Res Commun 197:840-8
    • (1993) Biochem Biophyl Res Commun , vol.197 , pp. 840-848
    • Steinert, P.M.1    Yang, J.M.2    Bale, S.J.3    Compton, J.G.4
  • 50
    • 23844432445 scopus 로고    scopus 로고
    • Small hairpin RNAs efficiently inhibit hepatitis C IRES-mediated gene expression in human tissue culture cells and a mouse model
    • Wang Q, Contag CH, Ilves H, Johnston BH, Kaspar RL (2005) Small hairpin RNAs efficiently inhibit hepatitis C IRES-mediated gene expression in human tissue culture cells and a mouse model. Mol Ther 12: 562-8
    • (2005) Mol Ther , vol.12 , pp. 562-568
    • Wang, Q.1    Contag, C.H.2    Ilves, H.3    Johnston, B.H.4    Kaspar, R.L.5
  • 51
    • 35348887160 scopus 로고    scopus 로고
    • Delivery and inhibition of reporter genes by small interfering RNAs in a mouse skin model
    • doi:10.1038/sj.jid.5700891
    • Wang Q, Ilves H, Chu P, Contag CH, Leake D, Johnston BH et al. (2007) Delivery and inhibition of reporter genes by small interfering RNAs in a mouse skin model. J Invest Dermatol doi:10.1038/sj.jid.5700891
    • (2007) J Invest Dermatol
    • Wang, Q.1    Ilves, H.2    Chu, P.3    Contag, C.H.4    Leake, D.5    Johnston, B.H.6
  • 53
    • 14844340023 scopus 로고    scopus 로고
    • Dissection of keratin dynamics: Different contributions of the actin and microtubule systems
    • Woll S, Windoffer R, Leube RE (2005) Dissection of keratin dynamics: different contributions of the actin and microtubule systems. Eur J Cell Biol 84:311-28
    • (2005) Eur J Cell Biol , vol.84 , pp. 311-328
    • Woll, S.1    Windoffer, R.2    Leube, R.E.3
  • 54
    • 11144349644 scopus 로고    scopus 로고
    • Overcoming functional redundancy to elicit pachyonychia congenita-like nail lesions in transgenic mice
    • Wong P, Domergue R, Coulombe PA (2005) Overcoming functional redundancy to elicit pachyonychia congenita-like nail lesions in transgenic mice. Mol Cell Biol 25:197-205
    • (2005) Mol Cell Biol , vol.25 , pp. 197-205
    • Wong, P.1    Domergue, R.2    Coulombe, P.A.3


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