Cationic nanomicelles for delivery of plasmids encoding interleukin-4 and interleukin-10 for prevention of autoimmune diabetes in mice

Pharmaceutical Research

Volumn 29, Issue 3, 2012, Pages 883-897

  Mandke, Rhishikesh ^a   Singh, Jagdish ^a  

^a NORTH DAKOTA STATE UNIVERSITY   (United States)

Author keywords

Chitosan; Diabetes; Gene delivery; Interleukin; Nanomicelles

Indexed keywords

CHITOSAN; GAMMA INTERFERON; GLUCOSE; INTERLEUKIN 10; INTERLEUKIN 4; N ACYL LOW MOLECULAR WEIGHT CHITOSAN; NAKED DNA; PLASMID DNA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; CATION; DRUG DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOIMMUNE DISEASE; BIOCOMPATIBILITY; CATIONIC NANOMICELLE; CONTROLLED STUDY; DIABETES MELLITUS; DRUG POTENTIATION; GENETIC TRANSFECTION; GLUCOSE BLOOD LEVEL; IN VIVO STUDY; INSULITIS; INTERMETHOD COMPARISON; MALE; MOUSE; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; PANCREAS ISLET; PLASMID; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; STREPTOZOCIN DIABETES; ANIMAL; BAGG ALBINO MOUSE; BLOOD; CHEMISTRY; GENETICS; INSULIN DEPENDENT DIABETES MELLITUS; METABOLISM; MICELLE; PANCREAS; PATHOLOGY;

ANIMALS; BLOOD GLUCOSE; CATIONS; CHITOSAN; DIABETES MELLITUS, TYPE 1; INTERFERON-GAMMA; INTERLEUKIN-10; INTERLEUKIN-4; MALE; MICE; MICE, INBRED BALB C; MICELLES; PANCREAS; PLASMIDS; TRANSFECTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84862312159     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-011-0616-1     Document Type: Article

References (41)

1. Bordelon H, Biris AS, Sabliov CM, Todd Monroe W. Characterization of plasmid DNA location within Chitosan/PLGA/pDNA Nanoparticle complexes designed for gene delivery. J Nanomaterials. 2011;2011:1-9.
2. Niidome T, Huang L. Gene therapy progress and prospects: Nonviral vectors. Gene Ther. 2002;9(24):1647-52.
3. Tros de Ilarduya C, Sun Y,Düzgüneş N.Gene delivery by lipoplexes and polyplexes. Eur J Pharm Sci. 2010;40(3):159-70.
4. Koh JJ, Ko KS, Lee M, Han S, Park JS, Kim SW. Degradable polymeric carrier for the delivery of IL-10 plasmid DNA to prevent autoimmune insulitis of NOD mice. Gene Ther. 2000;7 (24):2099-104.
5. Lim YB, Han SO, Kong HU, Lee Y, Park JS, Jeong B, et al. Biodegradable polyester, poly[alpha-(4-aminobutyl)-L-glycolic acid], as a non-toxic gene carrier. Pharm Res. 2000;17(7):811-6.
6. Wightman L,Kircheis R, Rössler V, Carotta S, Ruzicka R, Kursa M, et al. Different behavior of branched and linear polyethylenimine for gene delivery in vitro and in vivo. J Gene Med. 2001;3(4):362-72.
7. Dauty E, Remy JS, Blessing T, Behr JP. Dimerizable cationic detergents with a low cmc condense plasmid DNA into nanometric particles and transfect cells in culture. J Am Chem Soc. 2001;123(38):9227-34.
8. Prud'homme GJ, Chang Y. Prevention of autoimmune diabetes by intramuscular gene therapy with a nonviral vector encoding an interferon-gamma receptor/IgG1 fusion protein. Gene Ther. 1999;6(5):771-7.
9. Piccirillo CA, Chang Y, Prud'homme GJ. TGF-beta1 somatic gene therapy prevents autoimmune disease in nonobese diabetic mice. J Immunol. 1998;161(8):3950-6.
10. Nitta Y, Tashiro F, Tokui M, Shimada A, Takei I, Tabayashi K, et al. Systemic delivery of interleukin 10 by intramuscular injection of expression plasmid DNA prevents autoimmune diabetes in nonobese diabetic mice. Hum Gene Ther. 1998;9(12):1701-7.
11. Park L, Lee E, Lee S, Lim M, Hong H, Shin G, et al. TGFbeta plasmid construction and delivery for the prevention of type 1 diabetes. Ann N Y Acad Sci. 2008;1150:177-82.
12. Lee M, Park H, Youn J, Oh ET, Ko K, Kim S, et al. Interleukin-10 plasmid construction and delivery for the prevention of type 1 diabetes. Ann N Y Acad Sci. 2006;1079:313-9.
13. Cameron MJ, Arreaza GA, Zucker P, Chensue SW, Strieter RM, Chakrabarti S, et al. IL-4 prevents insulitis and insulin-dependent diabetes mellitus in nonobese diabetic mice by potentiation of regulatory T helper-2 cell function. J Immunol. 1997;159(10):4686-92.
14. Cameron MJ, Strathdee CA, Holmes KD, Arreaza GA, Dekaban GA, Delovitch TL. Biolistic-mediated interleukin 4 gene transfer prevents the onset of type 1 diabetes. Hum Gene Ther. 2000;11(12):1647-56.
15. Cameron MJ, Arreaza GA, Waldhauser L, Gauldie J, Delovitch TL. Immunotherapy of spontaneous type 1 diabetes in nonobese diabetic mice by systemic interleukin-4 treatment employing adenovirus vector-mediated gene transfer. Gene Ther. 2000;7(21):1840-6.
16. Faust A, Rothe H, Schade U, Lampeter E, Kolb H. Primary nonfunction of islet grafts in autoimmune diabetic nonobese diabetic mice is prevented by treatment with interleukin-4 and interleukin-10. Transplantation. 1996;62(5):648-52.
17. Wolff JA, Budker V. The mechanism of naked DNA uptake and expression. Adv Genet. 2005;54:3-20.
18. Roy K, Wang D, Hedley ML, Barman SP. Gene delivery with in-situ crosslinking polymer networks generates long-term systemic protein expression. Mol Ther. 2003;7(3):401-8.
19. Ko KS, Lee M, Koh JJ, Kim SW. Combined administration of plasmids encoding IL-4 and IL-10 prevents the development of autoimmune diabetes in nonobese diabetic mice. Mol Ther. 2001;4(4):313-6.
20. Lee M, Ko KS, Oh S, Kim SW. Prevention of autoimmune insulitis by delivery of a chimeric plasmid encoding interleukin-4 and interleukin-10. J Control Release. 2003;88(2):333-42.
21. Richard-Fiardo P, Payen E, Chèvre R, Zuber J, Letrou-Bonneval E, Beuzard Y, et al. Therapy of anemia in kidney failure, using plasmid encoding erythropoietin. Hum Gene Ther. 2008;19(4):331-42.
22. Jeon HJ, Oh TK, Kim OH, Kim ST. Delivery of factor VIII gene into skeletal muscle cells using lentiviral vector. Yonsei Med J. 2010;51(1):52-7.
23. Kormann MSD, Hasenpusch G, Aneja MK, Nica G, Flemmer AW, Herber-Jonat S, et al. Expression of therapeutic proteins after delivery of chemically modified mRNA in mice. Nat Biotechnol. 2011;29(2):154-7.
24. Marshall DJ, Leiden JM. Recent advances in skeletal-muscle-based gene therapy. Curr Opin Genet Dev. 1998;8(3):360-5.
25. Blau HM, Springer ML. Muscle-mediated gene therapy. N Engl J Med. 1995;333(23):1554-6.
26. Kessler PD, Podsakoff GM, Chen X, McQuiston SA, Colosi PC, Matelis LA, et al. Gene delivery to skeletal muscle results in sustained expression and systemic delivery of a therapeutic protein. Proc Natl Acad Sci U S A. 1996;93(24):14082-7.
27. Mandke R, Singh J. Effect of acyl chain length and unsaturation on physicochemical properties and transfection efficiency of N-acyl substituted low molecular weight chitosan. J Pharm. Sci. In press.
28. Kawasaki E, Abiru N, Eguchi K. Prevention of type 1 diabetes: from the view point of beta cell damage. Diabetes Res Clin Pract. 2004;66 Suppl 1:S27-32.
29. Biolegend. Mouse ELISA MaxTM Deluxe Set Technical Data Sheet, available at www.Biolegend.com. 2011
30. Basarkar A, Singh J. Poly (lactide-co-glycolide)-polymethacrylate nanoparticles for intramuscular delivery of plasmid encoding interleukin-10 to prevent autoimmune diabetes in mice. Pharm Res. 2009;26(1):72-81.
31. Leong KW, Mao HQ, Truong-Le VL, Roy K, Walsh SM, August JT. DNA-polycation nanospheres as non-viral gene delivery vehicles. J Control Release. 1998;53(1-3):183-93.
32. Yudovin-Farber I, Eliyahu H, Domb AJ. Synthesis of cationic polysaccharides and use for in vitro transfection. Cold Spring Harb. Protoc. 2011;2011(1):pdb.prot5553.
33. Gargouri M, Sapin A, Bouli S, Becuwe P, Merlin JL, Maincent P. Optimization of a new non-viral vector for transfection: Eudragit nanoparticles for the delivery of a DNA plasmid. Technol Cancer Res Treat. 2009;8(6):433-44.
34. Cohen JL, Schubert S, Wich PR, Cui L, Cohen JA, Mynar JL, et al. Acid-degradable cationic dextran particles for the delivery of siRNA Therapeutics. Bioconjug Chem. 2011;22(6):1056-65.
35. Behr J-P. The proton sponge: a trick to enter cells the viruses did not exploit. Chimia. 1997;51(1-2):34-6.
36. Chernajovsky Y, Gould DJ, Podhajcer OL. Gene therapy for autoimmune diseases: quo vadis? Nat Rev Immunol. 2004;4(10):800-11.
37. Li L, Yi Z, Tisch R, Wang B. Immunotherapy of type 1 diabetes. Arch Immunol Ther Exp. 2008;56:227-36.
38. Wu KK, Huan Y. Streptozotocin-induced diabetic models in mice and rats. Curr. Protoc. Pharmacol. 2008;40:5.47.1-5.47.14.
39. Schmidt RE, Dorsey DA, Beaudet LN, Frederick KE, Parvin CA, Plurad SB, et al. Non-obese diabetic mice rapidly develop dramatic sympathetic neuritic dystrophy. Am J Pathol. 2003;163(5):2077-91.
40. Lee M-J, Cho S-S, You J-R, Lee Y, Kang B-D, Choi JS, et al. Intraperitoneal gene delivery mediated by a novel cationic liposome in a peritoneal disseminated ovarian cancer model. Gene Ther. 2002;9(13):859-66.
41. DevendraD, Eisenbarth GS. 17. Immunologic endocrine disorders. J Allergy Clin Immunol. 2003;111(2 Suppl):S624-36.