Optimization of a new non-viral vector for transfection: Eudragit nanoparticles for the delivery of a DnA Plasmid

Technology in Cancer Research and Treatment

Volumn 8, Issue 6, 2009, Pages 433-444

  Gargouri, M ^a   Sapin, A ^a   Bouali, S ^a,b   Becuwe, P ^a   Merlin, J L ^a,b   Maincent, P ^a  

^a UNIVERSITÉ DE LORRAINE   (France)

^b CENTRE ALEXIS VAUTRIN   (France)

Author keywords

Gene therapy and delivery; Nanoparticles

Indexed keywords

DNA; EUDRAGIT; GREEN FLUORESCENT PROTEIN; LIPOFECTAMINE; NANOPARTICLE; POLYACRYLIC ACID;

ADSORPTION; ARTICLE; CELL STRAIN MCF 7; CELL TYPE; CONTROLLED STUDY; DRUG SYNTHESIS; EMULSION; FLOW CYTOMETRY; GENE EXPRESSION; GENE TARGETING; HUMAN; HUMAN CELL; MITOCHONDRION; NITROBLUE TETRAZOLIUM TEST; NONVIRAL GENE DELIVERY SYSTEM; NONVIRAL GENE THERAPY; PARTICLE SIZE; REPORTER GENE; TRANSGENE; ZETA POTENTIAL;

EID: 74049124294     PISSN: 15330346     EISSN: None     Source Type: Journal    
DOI: 10.1177/153303460900800605     Document Type: Article

References (47)

1. Roques, C., Fattal, E.Fromes, Y. Comparison of toxicity and transfection efficiency of amphiphilic block copolymers and polycationic polymers in striated muscles. J Gene Med 11, 240-249 (2009).
2. Yiu, H. H., McBain, S. C., Lethbridge, Z. A., Lees, M. R.Dobson, J. Preparation and characterization of polyethylenimine-coated Fe(3) O(4)-MCM-48 nanocomposite particles as a novel agent for magnet-assisted transfection. J Biomed Mater Res A, (2009).
3. Kay, M. A., Glorioso, J. C., Naldini, L. Viral vectors for gene therapy: the art of turning infectious agents into vehicles of therapeutics. Nat Med 7, 33-40 (2001).
4. Thomas, C. E., Ehrhardt, A., Kay, M. A. Progress and problems with the use of viral vectors for gene therapy. Nat Rev Genet 4, 346-358 (2003).
5. Leong, K. W., Mao, H. Q., Truong-Le, V. L., Roy, K., Walsh, S. M., August, J. T. DNA-polycation nanospheres as non-viral gene delivery vehicles. J Control Release 53, 183-193 (1998).
6. Masotti, A., Mossa, G., Cametti, C., Ortaggi, G., Bianco, A., Grosso, N. D., Malizia, D., Esposito, C. Comparison of different commercially available cationic liposome-DNA lipoplexes: Parameters influencing toxicity and transfection efficiency. Colloids Surf B Biointerfaces 68, 136-144 (2008).
7. Higashi, T., Khalil, I. A., Maiti, K. K., Lee, W. S., Akita, H., Harashima, H., Chung, S. K. Novel lipidated sorbitol-based molecular transporters for non-viral gene delivery. J Control Release 136, 140-147 (2009).
8. Yingyongnarongkul, B. E., Radchatawedchakoon, W., Krajarng, A., Watanapokasin, R., Suksamrarn, A. High transfection efficiency and low toxicity cationic lipids with aminoglycerol-diamine conjugate. Bioorg Med Chem 17, 176-188 (2009).
9. Li, L., Nie, Y., Ye, D., Cai, G. An easy protocol for on-chip transfection of COS-7 cells with a cationic lipid-based reagent. lab Chip 9, 2230-2233 (2009).
10. Wu, H., Ramachandran, C., Bielinska, A. U., Kingzett, K., Sun, R., Weiner, N. D.Roessler, B. J. Topical transfection using plasmid DNA in a water-in-oil nanoemulsion. Int J Pharm 221, 23-34 (2001).
11. Wang, Y., Wang, L. S., Goh, S. H.Yang, Y. Y. Synthesis and characterization of cationic micelles self-assembled from a biodegradable copolymer for gene delivery. Biomacromolecules 8, 1028-1037 (2007).
12. Zhang, X. Q., Intra, J.Salem, A. K. Comparative study of poly (lactic-co-glycolic acid)-poly ethyleneimine-plasmid DNA micro-particles prepared using double emulsion methods. J Microencapsul 25, 1-12 (2008).
13. Green, J. J., Zhou, B. Y., Mitalipova, M. M., Beard, C., Langer, R., Jaenisch, R.Anderson, D. G. Nanoparticles for gene transfer to human embryonic stem cell colonies. Nano lett 8, 3126-3130 (2008).
14. Yang, F., Green, J. J., Dinio, T., Keung, L., Cho, S. W., Park, H., Langer, R., Anderson, D. G. Gene delivery to human adult and embryonic cell-derived stem cells using biodegradable nanoparticulate polymeric vectors. Gene Ther 16, 533-546 (2009).
15. De Smedt, S. C., Demeester, J., Hennink, W. E. Cationic polymer based gene delivery systems. Pharm Res 17, 113-26 (2000).
16. Park, T. G., Jeong, J. H., Kim, S. W. Current status of polymeric gene delivery systems. Adv Drug Deliv Rev 58, 467-486 (2006).
17. Gebhart, C. L., Kabanov, A. V. Perspectives on Polymeric Gene Delivery. J Bioact and Compat Pol 18, 147-166 (2003).
18. Lee, M., Kim, S. W. Polyethylene glycol-conjugated copolymers for plasmid DNA delivery. Pharm Res 22, 1-10 (2005).
19. Mansouri, S., Lavigne, P., Corsi, K., Benderdour, M., Beaumont, E.Fernandes, J. C. Chitosan-DNA nanoparticles as non-viral vectors in gene therapy: strategies to improve transfection efficacy. eur J Pharm Biopharm 57, 1-8 (2004).
20. Kichler, A. Gene transfer with modified polyethylenimines. J Gene Med 6 Suppl 1, S3-10 (2004).
21. Vicennati, P., Giuliano, A., Ortaggi, G., Masotti, A. Polyethylenimine in medicinal chemistry. Curr Med Chem 15, 2826-2839 (2008).
22. Merlin, J. L., N'Doye, A., Bouriez, T., Dolivet, G. Polyethylenimine Derivatives as Potent Nonviral Vectors for Gene Transfer. Drug News Perspect 15, 445-451 (2002).
23. Ndoye, A., Dolivet, G., Hogset, A., Leroux, A., Fifre, A., Erbacher, P., Berg, K., Behr, J. P., Guillemin, F.Merlin, J. L. Eradication of p53-mutated head and neck squamous cell carcinoma xenografts using nonviral p53 gene therapy and photochemical internalization. Mol Ther 13, 1156-1162 (2006).
24. Christiaens, B., Dubruel, P., Grooten, J., Goethals, M., Vandekerck-hove, J., Schacht, E., Rosseneu, M. Enhancement of polymethacrylate-mediated gene delivery by Penetratin. eur J Pharm Sci 24, 525-537 (2005).
25. Panyam, J., Labhasetwar, V. Biodegradable nanoparticles for drug and gene delivery to cells and tissue. Adv Drug Deliv Rev 55, 329-347 (2003).
26. Vasir, J. K.Labhasetwar, V. Biodegradable nanoparticles for cytosolic delivery of therapeutics. Adv Drug Deliv Rev 59, 718-728 (2007).
27. Kneuer, C., Ehrhardt, C., Bakowsky, H., Kumar, M. N., Oberle, V., Lehr, C. M., Hoekstra, D.Bakowsky, U. The influence of physicochemical parameters on the efficacy of non-viral DNA transfection complexes: a comparative study. J Nanosci Nanotechnol 6, 2776-82 (2006).
28. Prabha, S., Zhou, W. Z., Panyam, J., Labhasetwar, V. Size-dependency of nanoparticle-mediated gene transfection: studies with fractionated nanoparticles. Int J Pharm 244, 105-115 (2002).
29. Brannon-Peppas, L., Ghosn, B., Roy, K., Cornetta, K. Encapsulation of nucleic acids and opportunities for cancer treatment. Pharm Res 24, 618-627 (2007).
30. Singh, M., Briones, M., Ott, G., O'Hagan, D. Cationic microparticles: A potent delivery system for DNA vaccines. Proc Natl Acad Sci USA 97, 811-816 (2000).
31. Esposito, E., Sebben, S., Cortesi, R., Menegatti, E., Nastruzzi, C. Preparation and characterization of cationic microspheres for gene delivery. Int J Pharm 189, 29-41 (1999).
32. Basarkar, A., Devineni, D., Palaniappan, R., Singh, J. Preparation, characterization, cytotoxicity and transfection efficiency of poly (DL-lactide-co-glycolide) and poly(DL-lactic acid) cationic nanoparticles for controlled delivery of plasmid DNA. Int J Pharm 343, 247-254 (2007).
33. Kasturi, S. P., Sachaphibulkij, K., Roy, K. Covalent conjugation of polyethyleneimine on biodegradable microparticles for delivery of plasmid DNA vaccines. Biomaterials 26, 6375-6385 (2005).
34. Ando, S., Putnam, D., Pack, D. W., Langer, R. PLGA microspheres containing plasmid DNA: preservation of supercoiled DNA via cry-opreparation and carbohydrate stabilization. J Pharm Sci 88, 126-130 (1999).
35. Prabha, S., Labhasetwar, V. Critical determinants in PLGA/PLA nanoparticle-mediated gene expression. Pharm Res 21, 354-364 (2004).
36. Fessi, H., Piusieux, F., Devissaguet, J. P., Ammoury, N., Benita, S. Nanocapsule formation by interfacial polymer deposition following solvent displacement. Int J Pharm 55, (1989).
37. Bodmeier, R., Chen, H., Tyle, P., Jarosz, P. Spontaneous formation of drug-containing acrylic nanoparticles. J Microencapsul 8, 161-170 (1991).
38. Alex, R., Bodmeier, R. Encapsulation of water-soluble drugs by a modified solvent evaporation method. I. Effect of process and formulation variables on drug entrapment. J Microencapsul 7, 347-355 (1990).
39. Minig, V., Kattan, Z., van Beeumen, J., Brunner, E., Becuwe, P. Identification of DDB2 Protein as a Transcriptional Regulator of Constitutive SOD2 Gene Expression in Human Breast Cancer Cells. J Biol Chem 284, 14165-14176 (2009).
40. Hoffart, V., Ubrich, N., Simonin, C., Babak, V., Vigneron, C., Hoffman, M., Lecompte, T., Maincent, P. Low molecular weight heparin-loaded polymeric nanoparticles: formulation, characterization, and release characteristics. Drug Dev Ind Pharm 28, 1091-1099 (2002).
41. Cortesi, R., Mischiati, C., Borgatti, M., Breda, L., Romanelli, A., Saviano, M., Pedone, C., Gambari, R., Nastruzzi, C. Formulations for natural and peptide nucleic acids based on cationic polymeric submicron particles. AAPS J 6, 10-21 (2004).
42. Kim, J. S., Kim, B. I., Maruyama, A., Akaike, T., Kim, S. W. A new non-viral DNA delivery vector: the terplex system. J Control Release 53, 175-182 (1998).
43. Thomas, M., Klibanov, A. M. Non-viral gene therapy: polycation-mediated DNA delivery. Appl Microbiol Biotechnol 62, 27-34 (2003).
44. Wang, C. C., Lu, J. N., Young, T. H. The alteration of cell membrane charge after cultured on polymer membranes. Biomaterials 28, 625-631 (2007).
45. Cherng, J. Y., van de Wetering, P., Talsma, H., Crommelin, D. J., Hennink, W. E. Effect of size and serum proteins on transfection efficiency of poly ((2-dimethylamino)ethyl methacrylate)-plasmid nanoparticles. Pharm Res 13, 1038-1042 (1996).
46. Fischer, D., Li, Y., Ahlemeyer, B., Krieglstein, J., Kissel, T. In vitro cytotoxicity testing of polycations: influence of polymer structure on cell viability and hemolysis. Biomaterials 24, 1121-1131 (2003).
47. Zhang, S., Zhao, B., Jiang, H., Wang, B., Ma, B. Cationic lipids and polymers mediated vectors for delivery of siRNA. J Control Release 123, 1-10 (2007).