Distinct properties of glycine receptor β+/α- interface: Unambiguously characterizing heteromeric interface reconstituted in homomeric protein

Journal of Biological Chemistry

Volumn 287, Issue 25, 2012, Pages 21244-21252

  Shan, Qiang ^a,b   Han, Lu ^b   Lynch, Joseph W ^b  

^a UNIVERSITY OF SYDNEY   (Australia)

^b UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CONFORMATIONAL CHANGE; DRUG DESIGN; EXTRACELLULAR; FUNCTIONAL INFORMATION; FUNCTIONAL PROPERTIES; GENERAL METHODOLOGIES; GLYCINE RECEPTOR; HIGH SENSITIVITY; PROTEIN INTERFACES; STRUCTURAL COMPONENT; SUBUNIT INTERFACES; VOLTAGE CLAMP;

PROTEINS;

AMINO ACIDS;

CHIMERIC PROTEIN; GLYCINE; GLYCINE RECEPTOR; GLYCINE RECEPTOR ALPHA; GLYCINE RECEPTOR BETA; TAURINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CHANNEL GATING; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; FEMALE; FLUOROMETRY; HOMOLOGOUS RECOMBINATION; MOLECULAR INTERACTION; MUTATIONAL ANALYSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; RESIDUE ANALYSIS; SENSITIVITY ANALYSIS; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS; VOLTAGE CLAMP;

ANIMALS; GLYCINE; HEK293 CELLS; HUMANS; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, QUATERNARY; RECEPTORS, GLYCINE; STRUCTURE-ACTIVITY RELATIONSHIP; XENOPUS LAEVIS;

EID: 84862291650     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.337741     Document Type: Article

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