Mapping of disulfide bonds within the amino-terminal extracellular domain of the inhibitory glycine receptor

Journal of Biological Chemistry

Volumn 284, Issue 52, 2009, Pages 36128-36136

  Vogel, Nicolas ^a   Kluck, Christoph J ^a   Melzer, Nima ^a   Schwarzinger, Stephan ^b   Breitinger, Ulrike ^a   Seeber, Silke ^a   Becker, Cord Michael ^a,c  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^b UNIVERSITY OF BAYREUTH   (Germany)

^c NONE   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

293 CELLS; CHLORIDE CHANNELS; CLOSE PROXIMITY; CYSTEINE RESIDUES; DISULFIDE BOND FORMATION; DISULFIDE BONDS; EXTRACELLULAR DOMAINS; GLYCINE RECEPTOR; HUMAN EMBRYONIC KIDNEYS; IN-VITRO; IN-VIVO; INTRACELLULAR RETENTION; LYSINE RESIDUES; MATRIX-ASSISTED LASER DESORPTION IONIZATION; NICOTINIC ACETYLCHOLINE RECEPTORS (NACHR); OXIDATIVE CONDITIONS; PROTEIN MATURATION; REFOLDING; SPECIFIC BONDS; TIME OF FLIGHT MASS SPECTROMETRY;

AMINO ACIDS; CHEMICAL BONDS; CHEMICAL MODIFICATION; CHLORINE COMPOUNDS; CIRCULAR DICHROISM SPECTROSCOPY; CRYSTAL STRUCTURE; DESORPTION; DICHROISM; ELECTROCHEMICAL SENSORS; ELECTROCHROMIC DEVICES; ENZYME ACTIVITY; MASS SPECTROMETERS; MASS SPECTROMETRY; POLYACRYLATES;

REDUCTION;

CYSTEINE; GLYCINE RECEPTOR; GLYCINE RECEPTOR ALPHA 1; LYSINE; NICOTINIC RECEPTOR; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; CHEMICAL MODIFICATION; CIRCULAR DICHROISM; CONTROLLED STUDY; CRYSTAL STRUCTURE; DISULFIDE BOND; HETEROLOGOUS EXPRESSION; HUMAN; HUMAN CELL; IN VITRO STUDY; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; OXIDATION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN PROCESSING;

ANIMALS; CELL LINE; CHLORIDE CHANNELS; DISULFIDES; HUMANS; MICE; MODELS, MOLECULAR; PEPTIDE MAPPING; PROTEIN FOLDING; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, GLYCINE; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION;

STRYCHNOS TOXIFERA;

EID: 73649093785     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.043448     Document Type: Article

References (29)

1. Betz, H., and Laube, B. (2006) J. Neurochem. 97, 1600-1610
2. Breitinger, H. G., and Becker, C. M. (2002) ChemBioChem 3, 1042-1052
3. Becker, C. M., Hoch, W., and Betz, H. (1988) EMBO J. 7, 3717-3726
4. Grudzinska, J., Schemm, R., Haeger, S., Nicke, A., Schmalzing, G., Betz, H., and Laube, B. (2005) Neuron 45, 727-739
5. Bocquet, N., Prado de Carvalho, L., Cartaud, J., Neyton, J., Le Poupon, C., Taly, A., Grutter, T., Changeux, J. P., and Corringer, P. J. (2007) Nature 445, 116-119
6. Brejc, K., van Dijk, W. J., Klaassen, R. V., Schuurmans, M., van Der Oost, J., Smit, A. B., and Sixma, T. K. (2001) Nature 411, 269-276
7. Dellisanti, C. D., Yao, Y., Stroud, J. C., Wang, Z. Z., and Chen, L. (2007) Nat. Neurosci. 10, 953-962
8. Unwin, N. (2005) J. Mol. Biol. 346, 967-989
9. Gay, E. A., and Yakel, J. L. (2007) J. Physiol. 584, 727-733
10. Bocquet, N., Nury, H., Baaden, M., Le Poupon, C., Changeux, J. P., Delarue, M., and Corringer, P. J. (2009) Nature 457, 111-114
11. Rojas, L., Zuazaga, C., and Steinacker, A. (1991) Brain Res. 551, 10-15
12. Sumikawa, K., and Gehle, V. M. (1992) J. Biol. Chem. 267, 6286-6290
13. Kao, P. N., and Karlin, A. (1986) J. Biol. Chem. 261, 8085-8088
14. Rajendra, S., Vandenberg, R. J., Pierce, K. D., Cunningham, A. M., French, P. W., Barry, P. H., and Schofield, P. R. (1995) EMBO J. 14, 2987-2998
15. Breitinger, U., Breitinger, H. G., Bauer, F., Fahmy, K., Glockenhammer, D., and Becker, C. M. (2004) J. Biol. Chem. 279, 1627-1636
16. The UniProt Consortium (2008) Nucleic Acids Res. 36, D190-D195
17. Larkin, M. A., Blackshields, G., Brown, N. P., Chenna, R., McGettigan, P. A., McWilliam, H., Valentin, F., Wallace, I. M., Wilm, A., Lopez, R., Thompson, J. D., Gibson, T. J., and Higgins, D. G. (2007) Bioinformatics 23, 2947-2948
18. Arnold, K., Bordoli, L., Kopp, J., and Schwede, T. (2006) Bioinformatics 22, 195-201
19. Whitmore, L., and Wallace, B. A. (2008) Biopolymers 89, 392-400
20. Whitmore, L., and Wallace, B. A. (2004) Nucleic Acids Res. 32, W668-W673
21. Lees, J. G., Miles, A. J., Wien, F., and Wallace, B. A. (2006) Bioinformatics 22, 1955-1962
22. Oertel, J., Villmann, C., Kettenmann, H., Kirchhoff, F., and Becker, C. M. (2007) J. Biol. Chem. 282, 2798-2807
23. Legendre, P., Muller, E., Badiu, C. I., Meier, J., Vannier, C., and Triller, A. (2002) Mol. Pharmacol. 62, 817-827
24. Grenningloh, G., Rienitz, A., Schmitt, B., Methfessel, C., Zensen, M., Beyreuther, K., Gundelfinger, E. D., and Betz, H. (1987) Nature 328, 215-220
25. Becker, C. M. (1992) in Handbook of Experimental Pharmacology (Herken, H., and Hucho, F., eds) pp. 539-575, Springer, Heidelberg
26. Liu, Z., Ramanoudjame, G., Liu, D., Fox, R. O., Jayaraman, V., Kurnikova, M., and Cascio, M. (2008) Biochemistry 47, 9803-9810
27. Ruiz-Gómez, A., Vaello, M. L., Valdivieso, F., and Mayor, F., Jr. (1991) J. Biol. Chem. 266, 559-566
28. Pan, Z. H., Bähring, R., Grantyn, R., and Lipton, S. A. (1995) J. Neurosci. 15, 1384-1391
29. Thio, L. L., and Zhang, H. X. (2006) Neuroscience 139, 1315-1327