-
1
-
-
79952193925
-
-
WHO Available from
-
World malaria report, 2010, WHO.Available from: http://www.who.int/ malaria/world-malaria-report-2010/en/ index.html
-
(2010)
World Malaria Report
-
-
-
2
-
-
70350778454
-
New medicines to improve control and contribute to the eradication of malaria
-
Wells TNC, Alonso PL, Gutteridge WE.New medicines to improve control and contribute to the eradication of malaria.Nat Drug Discov Rev 2009;8:879-91
-
(2009)
Nat. Drug Discov. Rev.
, Issue.8
, pp. 879-891
-
-
Wells, T.N.C.1
Alonso, P.L.2
Gutteridge, W.E.3
-
3
-
-
84862276011
-
-
Available from
-
Available from: http://www.reuters.com/ article/2011/01/14/us-malaria- vaccinegsk- idUSTRE70D25L20110114
-
-
-
-
5
-
-
84862298503
-
-
Available from 6.Available from
-
Available from: http://www.mmv.org/ research-development/science- portfolio 6.Available from: 2010
-
(2010)
-
-
-
6
-
-
48249095940
-
In silico activity profiling reveals the mechanism of action of antimalarials discovered in a high-throughput screen
-
Plouffe D, Brinker A, McNamara C, et al.In silico activity profiling reveals the mechanism of action of antimalarials discovered in a high-throughput screen.Proc Natl Acad Sci USA 2008;105:9059-64
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 9059-9064
-
-
Plouffe, D.1
Brinker, A.2
McNamara, C.3
-
7
-
-
77952718950
-
Chemical genetics of Plasmodium falciparum
-
Guiguemd WA, Shelat AA, Bouck D., et al.Chemical genetics of Plasmodium falciparum.Nature 2010;465:311-15
-
(2010)
Nature
, vol.465
, pp. 311-315
-
-
Guiguemd, W.A.1
Shelat, A.A.2
Bouck, D.3
-
8
-
-
77952704258
-
Thousands of chemical starting points for antimalarial lead identification
-
Gamo F-J, Sanz LM, Vidal J., et al.Thousands of chemical starting points for antimalarial lead identification.Nature 2010;465:305-10
-
(2010)
Nature
, vol.465
, pp. 305-310
-
-
Gamo, F.-J.1
Sanz, L.M.2
Vidal, J.3
-
10
-
-
33947594387
-
Recent advances in antimalarial compounds and their patents
-
Mital A.Recent advances in antimalarial compounds and their patents.Curr Med Chem 2007;14:759-73
-
(2007)
Curr. Med. Chem.
, vol.14
, pp. 759-773
-
-
Mital, A.1
-
11
-
-
58149119593
-
A review of antiparasitic patents 1988- 2008
-
Monzote L.A review of antiparasitic patents (1988 - 2008).Recent Pat Antiinfect Drug Discov 2008;3:177-91
-
(2008)
Recent Pat Antiinfect. Drug Discov.
, Issue.3
, pp. 177-191
-
-
Monzote, L.1
-
13
-
-
67849084837
-
-
Seven Indian patents published in English in 2010 - 2011 were not readily obtainable and hence excluded from this review 15.The Searete patents were excluded from this analysis 16.Muraleedharan KM Avery MA.Progress in the development of peroxide-based anti-parasitic agents
-
Seven Indian patents published in English in 2010 - 2011 were not readily obtainable and hence excluded from this review 15.The Searete patents were excluded from this analysis 16.Muraleedharan KM, Avery MA.Progress in the development of peroxide-based anti-parasitic agents.Drug Discov Today 2009;14:793-803
-
(2009)
Drug Discov Today
, Issue.14
, pp. 793-803
-
-
-
15
-
-
79251599335
-
Plasmodium sensitivity to artemisinins: Magic bullets hit elusive targets
-
Ding XC, Beck H-P, Raso G.Plasmodium sensitivity to artemisinins: magic bullets hit elusive targets.Trends in Parasit 2011;27:73-81
-
(2011)
Trends in Parasit
, vol.27
, pp. 73-81
-
-
Ding, X.C.1
Beck, H.-P.2
Raso, G.3
-
19
-
-
79952533967
-
Synthesis in vitro antimalarial and cytotoxicity of artemisinin- aminoquinoline hybrids
-
Lombard MC, N'Da DN, Breytenbach JC, et al.Synthesis, in vitro antimalarial and cytotoxicity of artemisinin-aminoquinoline hybrids.Bioorg Med Chem Lett 2011;21:1683-6
-
(2011)
Bioorg Med. Chem. Lett.
, vol.21
, pp. 1683-1686
-
-
Lombard, M.C.1
N'Da, D.N.2
Breytenbach, J.C.3
-
22
-
-
84862286773
-
-
US.Army Medical Research and Material Command WO144102
-
The U.S.Army Medical Research and Material Command.Pentafluorosulfanyl analogs of mefloquine.WO144102; 2010
-
(2010)
Pentafluorosulfanyl Analogs of Mefloquine
-
-
-
23
-
-
80052809069
-
-
U.S.Army Medical Research and Material Command. WO144101
-
The U.S.Army Medical Research and Material Command.Next generation quinoloine methanols.WO144101; 2010
-
(2010)
Next Generation Quinoloine Methanols
-
-
-
25
-
-
77949285672
-
Anti-Malarial activity of a non-Piperidine library of next generation quinoline methanols
-
Milner E, McCalmont W, Bhonsle J, et al.Anti-malarial activity of a non-piperidine library of next generation quinoline methanols Malaria J.2010;9:51
-
(2010)
Malaria J.
, vol.9
, pp. 51
-
-
Milner, E.1
McCalmont, W.2
Bhonsle, J.3
-
27
-
-
84862298476
-
-
Designmedix Inc Portland State University WO065925
-
Designmedix, Inc., Portland State University.Modified chloroquines with branched moiety.WO065925; 2010
-
(2010)
Modified Chloroquines with Branched Moiety
-
-
-
34
-
-
84862276791
-
-
Board of Regents University of Texas system, Monash University 2,4-Triazolo 1,5- a]pyrimidine derivatives as dihydroorotate dehydrogenase inhibitors and their preparation, pharmaceutical compositions and use in the treatment of malaria.WO041304
-
Board of Regents University of Texas system, Monash University, Medicines for Malaria Venture.1,2,4-Triazolo[1,5- a]pyrimidine derivatives as dihydroorotate dehydrogenase inhibitors and their preparation, pharmaceutical compositions and use in the treatment of malaria.WO041304; 2011
-
(2011)
Medicines for Malaria Venture
, vol.1
-
-
-
40
-
-
84862298482
-
-
CNRS, Technische Universitat Carlowilhelmina Zu Braunchschweig [2,3-b]pyridine and 5 6 7,8- tetrahydrothieno[ 2,3-b]quinoline useful in the treatment of malaria.WO042860
-
CNRS, Technische Universitat Carlowilhelmina Zu Braunchschweig. Preparation of new derivatives of thieno [2,3-b]pyridine and 5,6,7,8- tetrahydrothieno[2,3-b]quinoline useful in the treatment of malaria.WO042860; 2011
-
(2011)
Preparation of new derivatives of thieno
-
-
-
46
-
-
42949139813
-
Synthesis and structure-activity relationships of 4-pyridones as potential antimalarials
-
Yeates CL, Batchelor JF, Capon EC, et al.Synthesis and structure-activity relationships of 4-pyridones as potential antimalarials.J Med Chem 2008;5:2845-52
-
(2008)
J. Med. Chem.
, vol.5
, pp. 2845-2852
-
-
Yeates, C.L.1
Batchelor, J.F.2
Capon, E.C.3
-
48
-
-
84862298487
-
-
Department of Health and Human Services as representative of the United States of America. WO011537
-
Department of Health and Human Services as representative of the United States of America.Inhibitors of the plasmodial surface anion channel as antimalarials.WO011537; 2010
-
(2010)
Inhibitors of the Plasmodial Surface Anion Channel as Antimalarials
-
-
-
58
-
-
79955542813
-
Pharmacokinetics of solithromycin (CEM-101) after single or multiple oral doses and effects of food on single-dose bioavailability in healthy adult subjects
-
Still JG, Schranz J, Degenhardt TP, et al.Pharmacokinetics of solithromycin (CEM-101) after single or multiple oral doses and effects of food on single-dose bioavailability in healthy adult subjects.Antimicrob Agents Chemother 2011;55:1997-2003
-
(2011)
Antimicrob. Agents Chemother.
, vol.55
, pp. 1997-2003
-
-
Still, J.G.1
Schranz, J.2
Degenhardt, T.P.3
-
71
-
-
0038076318
-
A randomised comparison of chloroquine and chloroquine plus ketotifen in the treatment of acute, uncomplicated, P.falciparum in children
-
Sowunmi A.A randomised comparison of chloroquine and chloroquine plus ketotifen in the treatment of acute, uncomplicated, P.falciparum in children.Ann Trop Med Parasitol 2003;97:103-17
-
(2003)
Ann. Trop. Med. Parasitol.
, vol.97
, pp. 103-117
-
-
Sowunmi, A.1
-
75
-
-
78651277080
-
Synthesis and structure-activity relationships of novel benzoxaboroles as a new class of antimalarial agents
-
Zhang Y-K,, Plattner JJ, Freund YR, et al.Synthesis and structure-activity relationships of novel benzoxaboroles as a new class of antimalarial agents.Bioorg Med Chem Lett 2011;21:644-51
-
(2011)
Bioorg Med. Chem. Lett.
, vol.21
, pp. 644-651
-
-
Zhang, Y.-K.1
Plattner, J.J.2
Freund, Y.R.3
-
93
-
-
38349088595
-
TLR7/9 Antagonists as therapeutics for immune-Mediated inflammatory disorders
-
Sun S, Rao NL, Venable J, et al.TLR7/9 Antagonists as therapeutics for immune-mediated inflammatory disorders.Inflamm Allerg Drug Targets 2007;6:223-5
-
(2007)
Inflamm. Allerg. Drug Targets
, vol.6
, pp. 223-225
-
-
Sun, S.1
Rao, N.L.2
Venable, J.3
-
94
-
-
33846911691
-
Malaria hemozoin is immunologically inert but radically enhances innate responses by presenting malaria DNA to toll-like receptor 9
-
Parroche P, Lauw FN, Goutagny N, et al.Malaria hemozoin is immunologically inert but radically enhances innate responses by presenting malaria DNA to toll-like receptor 9.Proc Natl Acad Sci USA 2007;104:1219-24
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 1219-1224
-
-
Parroche, P.1
Lauw, F.N.2
Goutagny, N.3
-
101
-
-
0015379983
-
Antimalarial activity of some 3,5-diamino-as-triazine derivatives
-
Rees RWA, Russell PB, Foell TJ, Bright RE.Antimalarial activity of some 3,5-diamino-as-triazine derivatives.J Med Chem 1972;15:859-61
-
(1972)
J. Med. Chem.
, vol.15
, pp. 859-861
-
-
Rees, R.W.A.1
Russell, P.B.2
Foell, T.J.3
Bright, R.E.4
-
111
-
-
84862278039
-
-
Available from
-
Available from: http://www.gsk.com/ collaborations/our-commitment.htm
-
-
-
-
112
-
-
84862278036
-
-
Available from
-
Available from: http://www.mmv.org/ research-development/ essentialinformation- scientists/target-productprofiles
-
-
-
-
113
-
-
84862278038
-
-
Available from: http://www.mmv.org/ research-development/science- portfolio
-
-
-
-
114
-
-
79959959354
-
The state of the art in anti-malarial drug discovery and development
-
Burrows JN, Chibale K, Wells TNC.The state of the art in anti-malarial drug discovery and development.Curr Top Med Chem 2011;11:1226-54
-
(2011)
Curr. Top. Med. Chem.
, Issue.11
, pp. 1226-1254
-
-
Burrows, J.N.1
Chibale, K.2
Wells, T.N.C.3
-
115
-
-
79952741062
-
Natural products as starting points for future anti-malarial therapies: Going back to our roots
-
Available from
-
Wells TNC.Natural products as starting points for future anti-malarial therapies: going back to our roots? Malaria J 2011;10:S3: Available from: http://www.malariajournal.com/content/pdf/1475- 2875-10-S1-S3.pdf
-
(2011)
Malaria J.
, vol.10
-
-
Wells, T.N.C.1
-
116
-
-
65349148002
-
The African network for drugs and diagnostics innovation
-
Mboya-Okeyo T, Ridley RG, Nwaka S, et al.The African network for drugs and diagnostics innovation.Lancet 2009;373:1507-8
-
Lancet 2009
, Issue.373
, pp. 1507-1508
-
-
Mboya-Okeyo, T.1
Ridley, R.G.2
Nwaka, S.3
|