The astroglial-derived S100β protein stimulates the expression of nitric oxide synthase in rodent macrophages through p38 MAP kinase activation

Life Sciences

Volumn 78, Issue 23, 2006, Pages 2707-2715

  Esposito, Giuseppe ^a   De Filippis, Daniele ^a   Cirillo, Carla ^b   Sarnelli, Giovanni ^b   Cuomo, Rosario ^b   Iuvone, Teresa ^a  

^a UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^b Faculty of Medicine   (Italy)

Author keywords

iNOS protein; Macrophages; Oxidative stress; p38 MAP kinase; S100 ; TNF

Indexed keywords

3 (4 METHYLPHENYLSULFONYL) 2 PROPENENITRILE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; CALCIUM BINDING PROTEIN; HYDROGEN PEROXIDE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; MITOGEN ACTIVATED PROTEIN KINASE P38; MITOGEN ACTIVATED PROTEIN KINASE P38 INHIBITOR; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE INHIBITOR; PROTEIN INHIBITOR; PROTEIN S100B; S METHYLPSEUDOTHIOUREA; THIOUREA DERIVATIVE; TOSYLLYSYL CHLOROMETHYL KETONE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; AUTOANTIGEN; BIOLOGICAL MARKER; DRUG DERIVATIVE; ENZYME INHIBITOR; MESSENGER RNA; NERVE GROWTH FACTOR; NOS2 PROTEIN, RAT; PROTEIN S 100; S 100 CALCIUM BINDING PROTEIN BETA SUBUNIT; S METHYLISOTHIOPSEUDOURONIUM; S-100 CALCIUM-BINDING PROTEIN BETA SUBUNIT; S-METHYLISOTHIOPSEUDOURONIUM;

ANIMAL CELL; ARTICLE; CELL MEMBRANE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME KINETICS; FUNCTIONAL PROTEOMICS; IMMUNOBIOLOGY; IMMUNOCHEMISTRY; IN VITRO STUDY; INFLAMMATION; LIPID PEROXIDATION; MACROGLIA; MACROPHAGE FUNCTION; MOUSE; NONHUMAN; OXIDATIVE STRESS; PERITONEUM MACROPHAGE; PHARMACOLOGICAL BLOCKING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SYNTHESIS; RAT; RODENT; SIGNAL TRANSDUCTION; ANIMAL; ASTROCYTE; BIOSYNTHESIS; DOSE RESPONSE; DRUG ANTAGONISM; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; METABOLISM;

ANIMALIA; RODENTIA;

ANIMALS; ASTROCYTES; AUTOANTIGENS; BIOLOGICAL MARKERS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; ISOTHIURONIUM; LIPID PEROXIDATION; MACROPHAGES, PERITONEAL; MICE; NERVE GROWTH FACTORS; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; OXIDATIVE STRESS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; RATS; RNA, MESSENGER; S100 PROTEINS;

EID: 33646071538     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lfs.2005.10.023     Document Type: Article

References (38)

1. Adami C., Sorci G., Blasi E., Agneletti A.L., Bistoni F., and Donato R. S100B expression in and effects on microglia. Glia 33 2 (2001) 131-142
2. Adami C., Bianchi R., Pula G., and Donato R. S100B-stimulated NO production by BV-2 microglia is independent of RAGE transducing activity but dependent on RAGE extracellular domain. Biochimica et Biophysica Acta 6;1742 1-3 (2004) 169-177
3. Azmitia E.C., Dolan K., and Whitaker-Azmitia P.M. S-100B but not NGF, EGF, insulin or calmodulin is a CNS serotonergic growth factor. Brain Research 21;516 2 (1990) 354-356
4. Barger, S.W., Wolchok, S.R., Van Eldik, L.J., Submitted for publicaton. Disulfide-linked S100 beta dimers and signal transduction. Biochimica et Biophysica Acta. 1160(1):105-12.
5. Bogdan C. Nitric oxide and the immune response. Nature Immunology 2 10 (2001) 907-916
6. Bhattacharyya A., Oppenheim R.W., Prevette D., Moore B.W., Brackenbury R., and Ratner N. S100 is present in developing chicken neurons and Schwann cells and promotes motor neuron survival in vivo. Journal of Neurobiology 23 4 (1992) 451-466
7. Carnuccio R., Di Rosa M., Ialenti A., Iuvone T., and Sautebin L. Selective inhibition by vasocortin of histamine release induced by dextran and concanavalin-A from rat peritoneal cells. British Journal of Pharmacology 98 1 (1989) 32-34
8. Di Rosa M., Radomski M., Carnuccio R., and Moncada S. Glucocorticoids inhibit the induction of nitric oxide synthase in macrophages. Biochemical and Biophysical Research Communications 172 (1990) 1246-1252
9. Geppert T.D., Whitehurst C.E., Thompson P., and Beutler B. Lipopolysaccharide signals activation of tumor necrosis factor biosynthesis through the ras/raf-1/MEK/MAPK pathway. Molecular Medicine 1 (1994) 93-103
10. Griscavage J.M., Wilk S., and Ignarro L.J. Serine and cysteine proteinase inhibitors prevent nitric oxide production by activated macrophages by interfering with transcription of the inducible NO synthase gene. Biochemical Biophysic Research Communication 215 (1995) 721-729
11. Fano G., Mariggio M.A., Angelella P., Nicoletti I., Antonica A., Fulle S., and Calissano P. The S-100 protein causes an increase of intracellular calcium and death of PC12 cells. Neuroscience 3 4 (1993) 919-925
12. Griffin W.S., Stanley L.C., Ling C., White L., MacLeod V., Perrot L.J., White III C.L., and Araoz C. Brain interleukin 1 and S-100 immunoreactivity are elevated in Down syndrome and Alzheimer disease. Proceedings of the National Academy of Sciences of the United States of America 86 19 (1989) 7611-7615
13. Griffin W.S., Sheng J.G., McKenzie J.E., Royston M.C., Gentleman S.M., Brumback R.A., Cork L.C., Del Bigio M.R., Roberts G.W., and Mrak R.E. Life-long overexpression of S100beta in Down's syndrome: implications for Alzheimer pathogenesis. Neurobiology of Aging 19 5 (1998) 401-405
14. Hibbs Jr. J.B., Taintor R.R., Vavrin Z., and Rachlin E.M. Nitric oxide: a cytotoxic activated macrophage effector molecule. Biochemical and Biophysical Research Communications 157 1 (1988) 87-94
15. Hsieh H.L., Schafer B.W., Weigle B., and Heizmann C.W. S100 protein translocation in response to extracellular S100 is mediated by receptor for advanced glycation endproducts in human endothelial cells. Biochemical and Biophysical Research Communications 9;316 3 (2004) 949-959
16. Hu J., and Van Eldik L.J. Glial-derived proteins activate cultured astrocytes and enhance beta amyloid-induced glial activation. Brain Research 842 (1999) 46-54
17. Hu J., Ferreira A., and Van Eldik L.J. S100beta induces neuronal cell death through nitric oxide release from astrocytes. Journal of Neurochemistry 69 6 (1997) 2294-2301
18. Huttunen H.J., Kuja-Panula J., Sorci G., Agneletti A.L., Donato R., and Rauvala H. Coregulation of neurite outgrowth and cell survival by amphoterin and S100 proteins through receptor for advanced glycation end products (RAGE) activation. The Journal of Biological Chemistry 275 51 (2000) 40096-40105
19. Ianaro A., Ialenti A., Maffia P., Sautebin L., Rombolà L., Carnuccio R., Iuvone T., D'Acquisto F., and Di Rosa M. Anti-inflammatory activity of macrolide antibiotics. The Journal of Pharmacology and Experimental Therapeutics 292 (2000) 156-163
20. Iuvone T., Esposito G., Esposito R., Santamaria R., Di Rosa M., and Izzo A.A. Neuroprotective effect of cannabidiol, a non-psychoactive component from Cannabis sativa, on beta-amyloid-induced toxicity in PC12 cells. Journal of Neurochemistry 89 1 (2004) 134-141
21. Jiang H., Shah S., and Hilt D.C. Organization, sequence, and expression of the murine S100 beta gene. Transcriptional regulation by cell type-specific cis-acting regulatory elements. Journal of Biological Chemistry 268 (1993) 20502-20511
22. Kao S.J., Lei H.C., Kuo C.T., Chang M.S., Chen B.C., Chang Y.C., Chiu W.T., and Lin C.H. Lipoteichoic acid induces nuclear factor-kappaB activation and nitric oxide synthase expression via phosphatidylinositol 3-kinase, Akt, and p38 MAPK in RAW 264.7 macrophages. Immunology 15 3 (2005) 366-374
23. Kligman D., and Marshak D.R. Purification and characterization of a neurite extension factor from bovine brain. Proceedings of the National Academy of Sciences of the United States of America 82 20 (1985) 7136-7139
24. Kim H., Lee H.S., Chang K.T., Ko T.H., Baek K.J., and Kwon N.S. Chloromethyl ketones block induction of nitric oxide synthase in murine macrophages by preventing activation of nuclear factor-kappa B. Journal of Immunology 1;154 9 (1995) 4741-4748
25. Mihara M., and Uchiyama M. Determination of malonaldehyde precursor in tissues by thiobarbituric acid test. Analytical Biochemistry 86 1 (1978) 271-278
26. Moncada S., Palmer R.M.J., and Higgs E.A. Nitric oxide: physiology, pathophysiology and pharmacology. Pharmacological Reviews 43 (1991) 109-142
27. Mosman T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxic assay. Journal Immunological Methods 65 (1983) 53-63
28. Petrova T.V., Hu J., and Van Eldik L.J. Modulation of glial activation by astrocyte-derived protein S100B: differential responses of astrocyte and microglial cultures. Brain Research 853 1 (2000) 74-80
29. Pierce J.W., Schoenleber R., Jesmok G., Best J., Moore S.A., Collins T., and Gerritsen M.E. Novel inhibitors of cytokine-induced IkappaBalpha phosphorylation and endothelial cell adhesion molecule expression show anti-inflammatory effects in vivo. Journal of Biological Chemistry 272 (1997) 21096-21103
30. Shanmugam N., Kim Y.S., Lanting L., and Natarajan R. Regulation of cyclooxygenase-2 expression in monocytes by ligation of the receptor for advanced glycation end products. The Journal of Biological Chemistry 278 37 (2003) 34834-34844
31. Sorci G., Riuzzi F., Agneletti A.L., Marchetti C., and Donato R. S100B inhibits myogenic differentiation and myotube formation in a RAGE-independent manner. Molecular and Cellular Biology 23 14 (2003) 4870-4881
32. Sorci G., Riuzzi F., Agneletti A.L., Marchetti C., and Donato R. S100B causes apoptosis in a myoblast cell line in a RAGE-independent manner. Journal of Cellular Physiology 199 2 (2004) 274-283
33. Togo T., Katsuse O., and Iseki E. Nitric oxide pathways in Alzheimer's disease and other neurodegenerative dementias. Neurological Research 26 5 (2004) 563-566
34. Van Eldik L.J., and Griffin W.S. S100 beta expression in Alzheimer's disease: relation to neuropathology in brain regions. Biochimica et Biophysica Acta 1223 3 (1994) 398-403
35. Van Eldik L.J., Christie-Pope B., Bolin L.M., Shooter E.M., and Whetsell Jr. W.O. Neurotrophic activity of S-100 beta in cultures of dorsal root ganglia from embryonic chick and fetal rat. Brain Research 1;542 2 (1991) 280-285
36. Winningham-Major F., Staecker J.L., Barger S.W., Coats S., and Van Eldik L.J. Neurite extension and neuronal survival activities of recombinant S100 beta proteins that differ in the content and position of cysteine residues. The Journal of Cell Biology 109 6 Pt 1 (1989) 3063-3071
37. Wulczyn F.G., Krappmann D., and Scheidereit C. The NF-kappa B/Rel and I kappa B gene families: mediators of immune response and inflammation. Journal of Molecular Medicine 74 12 (1996) 749-769
38. Zimmer D.B., Cornwall E.H., Landar A., and Song W. The S100 protein family: history, function, and expression. Brain Research Bulletin 37 4 (1995) 417-429