Disruption of the folate pathway in zebrafish causes developmental defects

BMC Developmental Biology

Volumn 12, Issue , 2012, Pages

  Lee, Marina S ^a   Bonner, Jenna R ^a,b   Bernard, David J ^a   Sanchez, Erica L ^a,c   Sause, Eric T ^a,d   Prentice, R Reid ^a,e   Burgess, Shawn M ^a   Brody, Lawrence C ^a  

^a NATIONAL HUMAN GENOME RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF WASHINGTON   (United States)

^d NATIONAL CANCER INSTITUTE   (United States)

^e ILLUMINA INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DANIO RERIO;

DIHYDROFOLATE REDUCTASE; FOLIC ACID; FOLIC ACID ANTAGONIST; METHOTREXATE;

ANIMAL; ARTICLE; CELL CYCLE; CELL DIFFERENTIATION; DRUG EFFECT; EMBRYO DEVELOPMENT; HUMAN; METABOLISM; PRENATAL DEVELOPMENT; ZEBRA FISH;

ANIMALS; CELL CYCLE; CELL DIFFERENTIATION; EMBRYONIC DEVELOPMENT; FOLIC ACID; FOLIC ACID ANTAGONISTS; HUMANS; METABOLIC NETWORKS AND PATHWAYS; METHOTREXATE; TETRAHYDROFOLATE DEHYDROGENASE; ZEBRAFISH;

EID: 84862227253     PISSN: None     EISSN: 1471213X     Source Type: Journal    
DOI: 10.1186/1471-213X-12-12     Document Type: Article

References (40)

1. Mutated methylenetetrahydrofolate reductase as a risk factor for spina bifida. van der Put NM, Steegers-Theunissen RP, Frosst P, Trijbels FJ, Eskes TK, van den Heuvel LP, Mariman EC, den Heyer M, Rozen R, Blom HJ, Lancet 1995 346 8982 1070 1071 10.1016/S0140-6736(95)91743-8 7564788
2. A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase. Frosst P, Blom HJ, Milos R, Goyette P, Sheppard CA, Matthews RG, Boers GJ, den Heijer M, Kluijtmans LA, van den Heuvel LP, et al. Nat Genet 1995 10 1 111 113 10.1038/ng0595-111 7647779
3. A methylenetetrahydrofolate reductase polymorphism and the risk of colorectal cancer. Chen J, Giovannucci E, Kelsey K, Rimm EB, Stampfer MJ, Colditz GA, Spiegelman D, Willett WC, Hunter DJ, Cancer Res 1996 56 21 4862 4864 8895734
4. The role of the polymorphic genes apolipoprotein E and methylene- tetrahydrofolate reductase in the development of dementia of the Alzheimer type. Regland B, Blennow K, Germgard T, Koch-Schmidt AC, Gottfries CG, Dement Geriatr Cogn Disord 1999 10 4 245 251 10.1159/000017127 10364640
5. Prevention of neural tube defects: results of the Medical Research Council Vitamin Study. MRC Vitamin Study Research Group. Lancet 1991 338 8760 131 137 1677062
6. An update to the list of mouse mutants with neural tube closure defects and advances toward a complete genetic perspective of neural tube closure. Harris MJ, Juriloff DM, Birth Defects Res A Clin Mol Teratol 2010 88 8 653 669 10.1002/bdra.20676 20740593
7. Targeted disruption of the methionine synthase gene in mice. Swanson DA, Liu ML, Baker PJ, Garrett L, Stitzel M, Wu J, Harris M, Banerjee R, Shane B, Brody LC, Mol Cell Biol 2001 21 4 1058 1065 10.1128/MCB.21.4.1058-1065.2001 11158293
8. Drosophila dihydrofolate reductase mutations confer antifolate resistance to mammalian cells. Affleck JG, Al-Batayneh KM, Neumann K, Cole SP, Walker VK, Eur J Pharmacol 2006 529 1-3 71 78 16325803
9. Knockout of the folate transporter folt-1 causes germline and somatic defects in C. elegans. Austin MU, Liau WS, Balamurugan K, Ashokkumar B, Said HM, LaMunyon CW, BMC Dev Biol 2010 10 46 10.1186/1471-213X-10-46 20441590
10. Neurulation in the anterior trunk region of the zebrafish Brachydanio rerio. Schmitz B, Papan C, Campos-Ortega JA, Dev Genes Evol 1993 202 5 250 259
11. Molecular genetics of axis formation in zebrafish. Schier AF, Talbot WS, Annu Rev Genet 2005 39 561 613 10.1146/annurev.genet.37.110801.143752 16285872
12. Folic Acid. Bailey LB, Handbook of Vitamins CRC Press, Boca Raton, FL, Janos Zempleni RBR, McCormick Donald B, Suttie John W, 4 2007 385 412
13. Effect of dihydrofolate reductase gene knock-down on the expression of heart and neural crest derivatives expressed transcript 2 in zebrafish cardiac development. Sun SN, Gui YH, Wang YX, Qian LX, Jiang Q, Liu D, Song HY, Chinese Med J-Peking 2007 120 13 1166 1171
14. Fast Release Clones: A High Throughout Expression Analysis. Thisse B, Thisse C, Direct Data Submission 2004
15. Methionine adenosyltransferase: structure and function. Kotb M, Geller AM, Pharmacol Ther 1993 59 2 125 143 10.1016/0163-7258(93)90042-C 8278461
16. Cloning, expression, and functional characterization of the beta regulatory subunit of human methionine adenosyltransferase (MAT II). LeGros HL, Halim AB, Geller AM, Kotb M, J Biol Chem 2000 275 4 2359 2366 10.1074/jbc.275.4.2359 10644686
17. Disruption of the mthfd1 gene reveals a monofunctional 10-formyltetrahydrofolate synthetase in mammalian mitochondria. Christensen KE, Patel H, Kuzmanov U, Mejia NR, MacKenzie RE, J Biol Chem 2005 280 9 7597 7602 15611115
18. NAD-dependent methylenetetrahydrofolate dehydrogenase is expressed by immortal cells. Mejia NR, MacKenzie RE, J Biol Chem 1985 260 27 14616 14620 3877056
19. Mitochondrial NAD-dependent methylenetetrahydrofolate dehydrogenase-methenyltetrahydrofolate cyclohydrolase is essential for embryonic development. Di Pietro E, Sirois J, Tremblay ML, MacKenzie RE, Mol Cell Biol 2002 22 12 4158 4166 10.1128/MCB.22.12.4158-4166.2002 12024029
20. Mammalian MTHFD2l encodes a mitochondrial methylenetetrahydrofolate dehydrogenase isozyme expressed in adult tissues. Bolusani S, Young BA, Cole NA, Tibbetts AS, Momb J, Bryant JD, Solmonson A, Appling DR, >J Biol Chem 2010 286 5166 5174
21. Computational method to predict mitochondrially imported proteins and their targeting sequences. Claros MG, Vincens P, Eur J Biochem 1996 241 3 779 786 10.1111/j.1432-1033.1996.00779.x 8944766
22. Retrovirally mediated complementation of the glyB phenotype. Cloning of a human gene encoding the carrier for entry of folates into mitochondria. Titus SA, Moran RG, J Biol Chem 2000 275 47 36811 36817 10.1074/jbc.M005163200 10978331
23. Anticancer antifolates: current status and future directions. McGuire JJ, Curr Pharm Des 2003 9 31 2593 2613 10.2174/1381612033453712 14529544
24. Antimetabolite-metabolite combination cancer chemotherapy. Effects of intraarterial methotrexate-intramuscular Citrovorum factor therapy in human cancer. Sullivan RD, Miller E, Sikes MP, Cancer 1959 12 1248 1262 10.1002/1097-0142(195911/12)12:6<1248::AID-CNCR2820120619>3.0.CO;2-2 13835650
25. Inhibition of zebrafish fgf8 pre-mRNA splicing with morpholino oligos: a quantifiable method for gene knockdown. Draper BW, Morcos PA, Kimmel CB, Genesis 2001 30 3 154 156 10.1002/gene.1053 11477696
26. Vertebrate genome evolution and the zebrafish gene map. Postlethwait JH, Yan YL, Gates MA, Horne S, Amores A, Brownlie A, Donovan A, Egan ES, Force A, Gong Z, et al. Nat Genet 1998 18 4 345 349 10.1038/ng0498-345 9537416
27. VANGL1 rare variants associated with neural tube defects affect convergent extension in zebrafish. Reynolds A, McDearmid JR, Lachance S, De Marco P, Merello E, Capra V, Gros P, Drapeau P, Kibar Z, Mech Dev 2010 127 7-8 385 392 20043994
28. Strategies of vertebrate neurulation and a re-evaluation of teleost neural tube formation. Lowery LA, Sive H, Mech Dev 2004 121 10 1189 1197 10.1016/j.mod.2004.04.022 15327780
29. Mthfd1 is an essential gene in mice and alters biomarkers of impaired one-carbon metabolism. MacFarlane AJ, Perry CA, Girnary HH, Gao D, Allen RH, Stabler SP, Shane B, Stover PJ, J Biol Chem 2009 284 3 1533 1539 19033438
30. Mice deficient in methylenetetrahydrofolate reductase exhibit hyperhomocysteinemia and decreased methylation capacity, with neuropathology and aortic lipid deposition. Chen Z, Karaplis AC, Ackerman SL, Pogribny IP, Melnyk S, Lussier-Cacan S, Chen MF, Pai A, John SW, Smith RS, et al. Hum Mol Genet 2001 10 5 433 443 10.1093/hmg/10.5.433 11181567
31. Effects of methotrexate on the developments of heart and vessel in zebrafish. Sun S, Gui YH, Wang YX, Qian LX, Liu XF, Jiang Q, Song HY, Acta Biochim Biophys Sin 2009 41 1 86 96 10.1093/abbs/gmn010 19129954
32. Identification of 315 genes essential for early zebrafish development. Amsterdam A, Nissen RM, Sun Z, Swindell EC, Farrington S, Hopkins N, Proc Natl Acad Sci U S A 2004 101 35 12792 12797 10.1073/pnas.0403929101 15256591
33. Identification of zebrafish insertional mutants with defects in visual system development and function. Gross JM, Perkins BD, Amsterdam A, Egana A, Darland T, Matsui JI, Sciascia S, Hopkins N, Dowling JE, Genetics 2005 170 1 245 261 10.1534/genetics.104.039727 15716491
34. Zebrafish mutations in gart and paics identify crucial roles for de novo purine synthesis in vertebrate pigmentation and ocular development. Ng A, Uribe RA, Yieh L, Nuckels R, Gross JM, Development 2009 136 15 2601 2611 10.1242/dev.038315 19570845
35. Westerfield M, The zebrafish book: a guide for the laboratory use of zebrafish (Danio rerio) M. Westerfield, Eugene, OR 4 2000
36. p53 activation by knockdown technologies. Robu ME, Larson JD, Nasevicius A, Beiraghi S, Brenner C, Farber SA, Ekker SC, PLoS Genet 2007 3 5 78 10.1371/journal.pgen.0030078 17530925
37. High-resolution in situ hybridization to whole-mount zebrafish embryos. Thisse C, Thisse B, Nat Protoc 2008 3 1 59 69 10.1038/nprot.2007.514 18193022
38. lin9 is required for mitosis and cell survival during early zebrafish development. Kleinschmidt MA, Wagner TU, Liedtke D, Spahr S, Samans B, Gaubatz S, J Biol Chem 2009 284 19 13119 13127 10.1074/jbc.M809635200 19278998
39. A zebrafish bmyb mutation causes genome instability and increased cancer susceptibility. Shepard JL, Amatruda JF, Stern HM, Subramanian A, Finkelstein D, Ziai J, Finley KR, Pfaff KL, Hersey C, Zhou Y, et al. Proc Natl Acad Sci U S A 2005 102 37 13194 13199 10.1073/pnas.0506583102 16150706
40. Analysis of early epidermal development in zebrafish. Webb AE, Kimelman D, Methods Mol Biol 2005 289 137 146 15502179