Neural precursors (NPCs) from adult L967Q mice display early commitment to "in vitro" neuronal differentiation and hyperexcitability

Experimental Neurology

Volumn 236, Issue 2, 2012, Pages 307-318

  DiFebo, Francesca ^a   Curti, Daniela ^a   Botti, Francesca ^a   Biella, Gerardo ^a   Bigini, Paolo ^b   Mennini, Tiziana ^b   Toselli, Mauro ^a  

^a UNIVERSITY OF PAVIA   (Italy)

^b MARIO NEGRI INSTITUTE FOR PHARMACOLOGICAL RESEARCH   (Italy)

Author keywords

Amyotrophic lateral sclerosis; Hyperexcitability; Motoneuron; Neural stem progenitor cells (NPCs); Neurodegeneration; Patch clamp; Sodium channel; Wobbler mouse

Indexed keywords

PROTEIN C FOS; SODIUM CHANNEL;

ACTION POTENTIAL; ADULT ANIMAL; AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ISOLATION; CELL LOSS; CELL MATURATION; CELL PROLIFERATION; CELL RENEWAL; CELL STRUCTURE; CONTROLLED STUDY; DISEASE MODEL; ELECTRIC ACTIVITY; ELECTROPHYSIOLOGY; FACILITATION; IN VITRO STUDY; L967Q MOUSE; MOTONEURON; MOUSE STRAIN; MUSCLE ATROPHY; NERVE CELL CHARACTERISTICS AND FUNCTIONS; NERVE CELL DEGENERATION; NERVE CELL DIFFERENTIATION; NERVE CELL HYPEREXCITABILITY; NERVE CELL NETWORK; NEURAL STEM CELL; NONHUMAN; PRIORITY JOURNAL; PROBABILITY; SODIUM CURRENT; SUBVENTRICULAR ZONE; WOBBLER MOUSE;

ACTION POTENTIALS; AGE FACTORS; AMINO ACID SUBSTITUTION; ANIMALS; CELL DIFFERENTIATION; CELL SURVIVAL; GLUTAMINE; LEUCINE; MICE; MICE, NEUROLOGIC MUTANTS; NEURAL STEM CELLS; NEUROGENESIS; NEURONS; SODIUM CHANNELS;

EID: 84862225293     PISSN: 00144886     EISSN: 10902430     Source Type: Journal    
DOI: 10.1016/j.expneurol.2012.05.010     Document Type: Article

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