Alfa-Lipoic acid protects testosterone secretion pathway and sperm quality against 4-tert-octylphenol induced reproductive toxicity

Ecotoxicology and Environmental Safety

Volumn 81, Issue , 2012, Pages 76-83

  Othman, Azza I ^a   El Missiry, Mohamed A ^a   Koriem, Khaled M ^b   El Sayed, Aml A ^a  

^a Mansoura University   (Egypt)

^b ADVANCED MEDICAL AND DENTAL INSTITUTE   (Malaysia)

Author keywords

Alkylphenols; Antioxidants; DNA; Hormones; Pollution; Proliferating index; Sperm quality; Testis

Indexed keywords

3(OR 17)BETA HYDROXYSTEROID DEHYDROGENASE; 4 TERT OCTYLPHENOL; DNA; GLUTATHIONE; GLUTATHIONE TRANSFERASE; MEMBRANE PROTEIN; PRASTERONE SULFATE; SEX HORMONE BINDING GLOBULIN; TESTOSTERONE; THIOCTIC ACID;

ANTIOXIDANT; DNA; HORMONE; SPERM; TESTOSTERONE; TOXICITY;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; BODY WEIGHT; CELL PROLIFERATION; CONTROLLED STUDY; DNA FRAGMENTATION; GERM CELL; HORMONE INHIBITION; HYPOTHALAMUS; MALE; MEMBRANE STRUCTURE; NONHUMAN; OXIDATIVE STRESS; PROTEIN DEPLETION; RAT; REPRODUCTIVE TOXICITY; SPERM; TESTIS CELL; TESTOSTERONE BLOOD LEVEL; TESTOSTERONE RELEASE;

17-HYDROXYSTEROID DEHYDROGENASES; ANIMALS; ANTIOXIDANTS; EPIDIDYMIS; GLUTATHIONE; GLUTATHIONE TRANSFERASE; MALE; OXIDATIVE STRESS; PHENOLS; RATS; RATS, WISTAR; REPRODUCTION; SECRETORY PATHWAY; SPERMATOZOA; SURFACE-ACTIVE AGENTS; TESTICULAR DISEASES; TESTIS; TESTOSTERONE; THIOCTIC ACID;

RATTUS;

EID: 84862224422     PISSN: 01476513     EISSN: 10902414     Source Type: Journal    
DOI: 10.1016/j.ecoenv.2012.04.018     Document Type: Article

References (76)

1. Aguilar-Mahecha A., Hales B.F., Robaire B. Chronic cyclophosphamide treatment alters the expression of stress response genes in rat male germ cells. Biol. Reprod. 2002, 664:1024-1032.
2. Aly H.A., Lightfoot D.A., El-Shemy H.A. Modulatory role of lipoic acid on lipopolysaccharide-induced oxidative stress in adult rat Sertoli cells in vitro. Chem. Biol. Interact. 2009, 1822-3:112-118.
3. Ashour A.E., Abdel-Hamied H.E., Korashy H.M., Al-Shabanah O.A., Abd-Allah A.R. Alpha-lipoic acid rebalances redox and immune-testicular milieu in septic rats. Chem. Biol. Interact. 2011, 1893:198-205.
4. Aydogan M., Barlas N. Effects of maternal 4-tert-octylphenol exposure on the reproductive tract of male rats at adulthood. Reprod. Toxicol. 2006, 223:455-460.
5. Aydogan M., Korkmaz A., Barlas N., Kolankaya D. The effect of vitamin C on bisphenol A, nonylphenol and octylphenol induced brain damages of male rats. Toxicology 2008, 2491:35-39.
6. Berensztein E.B., Sciara M.I., Rivarola M.A., Belgorosky A. Apoptosis and proliferation of human testicular somatic and germ cells during prepuberty: high rate of testicular growth in newborns mediated by decreased apoptosis. J. Clin. Endocrinol. Metab. 2002, 8711:5113-5118.
7. Bian Q., Qian J., Xu L., Chen J., Song L., Wang X. The toxic effects of 4-tert-octylphenol on the reproductive system of male rats. Food Chem. Toxicol. 2006, 448:1355-1361.
8. Biswas S., Chida A.S., Rahman I. Redox modifications of protein-thiols: emerging roles in cell signaling. Biochem. Pharmacol. 2006, 715:551-564.
9. Blake C.A., Boockfor F.R. Chronic administration of the environmental pollutant 4-tert-octylphenol to adult male rats interferes with the secretion of luteinizing hormone, follicle-stimulating hormone, prolactin, and testosterone. Biol. Reprod. 1997, 572:255-266.
10. Blake C.A., Boockfor F.R., Nair-Menon J.U., Millette C.F., Raychoudhury S.S., McCoy G.L. Effects of 4-tert-octylphenol given in drinking water for 4 months on the male reproductive system of Fischer 344 rats. Reprod. Toxicol. 2004, 181:43-51.
11. Brooke, D., Johnson, I., Mitchell, R., Watts, C., 2005. Environmental Risk Assessment: 4-Tert-Octylphenol, Science Report. Environment Agency Publisher, Rio House, Waterside Drive, Aztec West, Almondsbury, Bristol, UK, pp. 128-129.
12. Bock P.P., Karmer R., Paverka M.A. A simple assay for catalase determination. Cell Biol. Monogr. 1980, 71:44-74.
13. Boockfor F.R., Blake C.A. Chronic administration of 4-tert-octylphenol to adult male rats causes shrinkage of the testes and male accessory sex organs, disrupts spermatogenesis, and increases the incidence of sperm deformities. Biol. Reprod. 1997, 572:267-277.
14. Chan T.K., Todd D., Wong C.C. Tissue enzyme levels in erythrocyte glucose-6-phosphate dehydrogenase deficiency. J. Lab. Clin. Med. 1965, 666:937-942.
15. Chapin R.E., Delaney J., Wang Y., Lanning L., Davis B., Collins B., Mintz N., Wolfe G. The effects of 4-nonylphenol in rats: a multigeneration reproduction study. Toxicol. Sci. 1999, 521:80-91.
16. Chitra K.C., Latchoumycandane C., Mathur P.P. Effect of nonylphenol on the antioxidant system in epididymal sperm of rats. Arch. Toxicol. 2002, 769:545-551.
17. Codrington A.M., Hales B.F., Robaire B. Chronic cyclophosphamide exposure alters the profile of rat sperm nuclear matrix proteins. Biol. Reprod. 2007, 772:303-311.
18. Connell B.J., Saleh M., Khan B.V., Saleh T.M. Lipoic acid protects against reperfusion injury in the early stages of cerebral ischemia. Brain Res. 2011, 1375:128-136.
19. Davis J.G., Wan X.S., Ware J.H., Kennedy A.R. Dietary supplements reduce the cataractogenic potential of proton and HZE-particle radiation in mice. Radiat. Res. 2010, 1733:353-361.
20. Desouky O.S., Selim N.S., Elbakrawy E.M., Rezk R.A. Impact evaluation of alpha-lipoic acid in gamma-irradiated erythrocytes. Radiat. Phys. Chem. 2011, 803:446-452.
21. Guimaraes S.B., Santos J.M., Aragao A.A., de Sandes Kimura O., Barbosa P.H., de Vasconcelos P.R. Protective effect of alpha-lipoic acid in experimental spermatic cord torsion. Nutrition 2007, 231:76-80.
22. Gupta R.S., Kachhawa J.B., Chaudhary R. Antifertility effects of methanolic pod extract of Albizzia lebbeck L. Benth in male rats. Asian J. Androl. 2004, 62:155-159.
23. Habig W.H., Pabst M.J., Jakoby W.B. Glutathione S-transferases. The first enzymatic step in mercapturic acid formation. J. Biol. Chem. 1974, 24922:7130-7139.
24. Han D., Handelman G., Marcocci L., Sen C.K., Roy S., Kobuchi H., Tritschler H.J., Flohe L., Packer L. Lipoic acid increases de novo synthesis of cellular glutathione by improving cystine utilization. Biofactors 1997, 63:321-338.
25. Hejmej A., Kotula-Balak M., Galas J., Bilinska B. Effects of 4-tert-octylphenol on the testes and seminal vesicles in adult male bank voles. Reprod. Toxicol. 2011, 31(1):95-105.
26. Holmquist L., Stuchbury G., Berbaum K., Muscat S., Young S., Hager K., Engel J., Munch G. Lipoic acid as a novel treatment for Alzheimer's disease and related dementias. Pharmacol. Ther. 2007, 1131:154-164.
27. Ibrahim S.F., Osman K., Das S., Othman A.M., Majid N.A., Rahman M.P. A study of the antioxidant effect of alpha lipoic acids on sperm quality. Clinics Sao Paulo 2008, 634:545-550.
28. Isobe T., Nishiyama H., Nakashima V., Takada H. Distribution and behavior of nonylphenol, octylphenol, and nonylphenol monoethoxylate in Tokyo metropolitan area: their association with aquatic particles and sedimentary distributions. Environ. sci. technol. 2001, 35:1041-1049.
29. Ioannou Y.A., Chen F.W. Quantitation of DNA fragmentation in apoptosis. Nucleic Acids Res. 1996, 245:992-993.
30. Kabuto H., Amakawa M., Shishibori T. Exposure to bisphenol A during embryonic/fetal life and infancy increases oxidative injury and causes underdevelopment of the brain and testis in mice. Life Sci. 2004, 7424:2931-2940.
31. Katsuda S.I., Yoshida M., Isagawa S., Asagawa Y., Kuroda H., Watanabe T., Ando J., Takahashi M., Maekawa A. Dose- and treatment duration-related effects of p-tert-octylphenol on female rats. Reprod. Toxicol. 2000, 14(2):119-126.
32. Karageorgos N., Patsoukis N., Chroni E., Konstantinou D., Assimakopoulos S.F., Georgiou C. Effect of N-acetylcysteine, allopurinol and vitamin E on jaundice-induced brain oxidative stress in rats. Brain Res. 2006, 11111:203-212.
33. Karvonen M.J., Malm M. Colorimetric determination of fructose with indol. Scand. J. Clin. Lab. Invest. 1955, 74:305-307.
34. Kim, Kim B., Shim J.H., Gil J.E., Yoon Y.D., Kim J.H. Nonylphenol and octylphenol-induced apoptosis in human embryonic stem cells is related to Fas-Fas ligand pathway. Toxicol. Sci. 2006, 942:310-321.
35. Kim Kim, Shim B.K., Gil J.H., Yoon J.E., Kim, J.H.Y.D. Nonylphenol and octylphenol-induced apoptosis in human embryonic stem cells is related to Fas-Fas ligand pathway. Toxicol. Sci. 2006, 942:310-321.
36. Kim E., Goldberg M. Serum cholesterol assay using a stable Liebermann-Burchard reagent. Clin. Chem. 1969, 1512:1171-1179.
37. Korkmaz A., Ahbab M.A., Kolankaya D., Barlas N. Influence of vitamin C on bisphenol A, nonylphenol and octylphenol induced oxidative damages in liver of male rats. Food Chem. Toxicol. 2010, 4810:2865-2871.
38. Kumar T.R., Doreswamy K., Muralidhara B. Oxidative stress associated DNA damage in testis of mice: induction of abnormal sperms and effects on fertility. Mutat. Res.-Genet. Toxicol. Environ. Mutagen. 2002, 5131-2:103-111.
39. Laemmli U.K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 1970, 2275259:680-685.
40. Laws S.C., Carey S.A., Ferrell J.M., Bodman G.J., Cooper R.L. Estrogenic activity of octylphenol, nonylphenol, bisphenol A and methoxychlor in rats. Toxicol. Sci. 2000, 541:154-167.
41. Lee H.-B., Peart T.E., Gris G., Chan J. Endocrine-disrupting chemicals in industrial wastewater samples in Toronto, Ontario. Water Qual. Res. J. Can. 2002, 37:459-472.
42. Li Guo, Ning Y., Zhang Q., Li, D.S. Research for the effect of octylphenol on spermatogenesis and proteomic analysis in octylphenol-treated mice testes. Cell Biol. Int. 2011, 354:305-309.
43. Lowry O.H., Rosebrough N.J., Farr A.L., Randall R.J. Protein measurement with the Folin phenol reagent. J. Biol. Chem. 1951, 1931:265-275.
44. Manda K., Ueno M., Moritake T., Anzai K. Alpha-Lipoic acid attenuates x-irradiation-induced oxidative stress in mice. Cell Biol. Toxicol. 2007, 232:129-137.
45. Maruyama Y., Aoki N., Suzuki Y., Ohno Y., Imamura M., Saika T., Sinohara H., Yamamoto T. Sex-steroid-binding plasma protein SBP, testosterone, oestradiol and dehydroepiandrosterone DHEA in prepuberty and puberty. Acta Endocrinol. Copenhagen 1987, 1141:60-67.
46. Meeker J.D., Ehrlich S., Toth T.L., Wright D.L., Calafat A.M., Trisini A.T., Ye X., Hauser R. Semen quality and sperm DNA damage in relation to urinary bisphenol A among men from an infertility clinic. Reprod. Toxicol. 2010, 304:532-539.
47. Migliore L., Coppede F. Genetic and environmental factors in cancer and neurodegenerative diseases. Mutat. Res. 2002, 5122-3:135-153.
48. Mikkila T.F., Toppari J., Paranko J. Effects of neonatal exposure to 4-tert-octylphenol, diethylstilbestrol, and flutamide on steroidogenesis in infantile rat testis. Toxicol. Sci. 2006, 91(2):456-466.
49. Navari-Izzo F., Quartacci M.F., Sgherri C. Lipoic acid: a unique antioxidant in the detoxification of activated oxygen species. Plant Physiol. Biochem. 2002, 406-8:463-470.
50. Nimrod A.C., Benson W.H. Environmental estrogenic effects of alkylphenol ethoxylates. Crit. Rev. Toxicol. 1996, 263:335-364.
51. Nishikimi M., Appaji N., Yagi K. The occurrence of superoxide anion in the reaction of reduced phenazine methosulfate and molecular oxygen. Biochem. Biophys. Res. Commun. 1972, 462:849-854.
52. O'Neill C.A., Halliwell B., van der Vliet A., Davis P.A., Packer L., Tritschler H., Strohman W.J., Rieland T., Cross C.E., Reznick A.Z. Aldehyde-induced protein modifications in human plasma: protection by glutathione and dihydrolipoic acid. J. Lab. Clin. Med. 1994, 1243:359-370.
53. Ohkawa H., Wakatsuki A., Kaneda C. Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal. Biochem. 1982, 951:351-358.
54. Packer L., Tritschler H.J., Wessel K. Neuroprotection by the metabolic antioxidant alpha-lipoic acid. Free Radic. Biol. Med. 1997, 221-2:359-378.
55. Prahalathan C., Selvakumar E., Varalakshmi P. Lipoic acid modulates adriamycin-induced testicular toxicity. Reprod. Toxicol. 2006, 211:54-59.
56. Prins H.K., Loose J.A. Glutathione. Biochemical Methods in Red Cell Genetics, vol. 11 1969, Academic Press, N. Y. D. London, pp. 126-129 (Chapter 4).
57. Rajeev S.K., Reddy K.V. Sperm membrane protein profiles of fertile and infertile men: identification and characterization of fertility-associated sperm antigen. Hum. Reprod. 2004, 192:234-242.
58. Rashid H., Ahmad F., Rahman S., Ansari R.A., Bhatia K., Kaur M., Islam F., Raisuddin S. Iron deficiency augments bisphenol A-induced oxidative stress in rats. Toxicology 2009, 2561-2:7-12.
59. Rhee J.S., Kim R.O., Chang H.H., Lee J., Lee Y.M., Lee J.S. Endocrine disrupting chemicals modulate expression of O-methylguanine DNA methyltransferase O-MGMT gene in the hermaphroditic fish, Kryptolebias marmoratus. Comp. Biochem. Physiol. C Toxicol. Pharmacol. 2011, 1531:141-149.
60. Sainath S.B., Meena R., Venkata Suneel Kumar C.H., Kalapana P., Swetha K.N., Syamala Devi N., Sreenivasula Reddy P. Embryonic exposure to octylphenol induces changes in testosterone levels and disrupts reproductive efficiency in rats at their adulthood. Food Chem. Toxicol. 2011, 49:983-990.
61. Sambrook J., Fritsch E.F., Maniatis T. Molecular Cloning. A Laboratory Manual 1989, Cold Spring Harbor Laboratory, Cold spring Harbor. New York, p. 1121.
62. Selby C. Sex hormone binding globulin: origin, function and clinical significance. Ann. Clin. Biochem. 1990, 27(Part 6):532-541.
63. Sharma R.K., Pasqualotto F.F., Nelson D.R., Thomas A.J., Agarwal A. The reactive oxygen species-total antioxidant capacity score is a new measure of oxidative stress to predict male infertility. Hum. Reprod. 1999, 1411:2801-2807.
64. SIDS, 1994. SIDS Dossier on the OECD HPV Chemicals Phenol, 4-(1,1,3,3,-Tetramethylbutyl), Including SIDS IAR. Initial Assessment Report (1994) on Octylphenol. OECD, Paris.
65. Singh U., Jialal I. Alpha-lipoic acid supplementation and diabetes. Nutr. Rev. 2008, 6611:646-657.
66. Smith, Carney J.M., Starkereed P.E., Oliver C.N., Stadtman E.R., Floyd R.A., Markesbery W.R. Excess brain protein oxidation and enzyme dysfunction in normal aging and in Alzheimer-disease. Proc. Natl. Acad. Sci. USA 1991, 8823:10540-10543.
67. Smith, Shenvi S.V., Widlansky M., Suh J.H., Hagen T.M. Lipoic acid as a potential therapy for chronic diseases associated with oxidative stress. Curr. Med. Chem. 2004, 119:1135-1146.
68. Somani S.M., Husain K., Whitworth C., Trammell G.L., Malafa M., Rybak L.P. Dose-dependent protection by lipoic acid against cisplatin-induced nephrotoxicity in rats: antioxidant defense system. Pharmacol. Toxicol. 2000, 865:234-241.
69. Sundaram K., Panneerselvam K.S. Oxidative stress and DNA single strand breaks in skeletal muscle of aged rats: role of carnitine and lipoicacid. Biogerontology 2006, 72:111-118.
70. Suzuki Y.J., Tsuchiya M., Packer L. Thioctic acid and dihydrolipoic acid are novel antioxidants which interact with reactive oxygen species. Free Radic. Res. Commun. 1991, 155:255-263.
71. Talalay P. Hydroxysteroid dehydrogenase. Methods in Enzymology, vol. 11 1962, 512-516. Academic Press, New York. S.P. Cloowick, Kaplan (Eds.).
72. Tas N., Bakar B., Kasimcan M.O., Gazyagci S., Ayva S.K., Kilinc K., Evliyaoglu C. Evaluation of protective effects of the alpha lipoic acid after spinal cord injury: an animal study. Injury 2010, 4110:1068-1074.
73. Thibaut R., Porte C. Effects of endocrine disrupters on sex steroid synthesis and metabolism pathways in fish. J. Steroid Biochem. Mol. Biol. 2004, 925:485-494.
74. Trudeau V.L., Chiu S., Kennedy S.W., Brooks R.J. Octylphenol OP alters the expression of members of the amyloid protein family in the hypothalamus of the snapping turtle, Chelydra serpentina serpentina. Environ. Health Perspect. 2002, 1103:269-275.
75. Ying G.G., Williams B., Kookana R. Environmental fate of alkylphenols and alkylphenol ethoxylates-a review. Environ. Int. 2002, 283:215-226.
76. Zhang Y., Han P., Wu N., He B., Lu Y., Li S., Liu Y., Zhao S., Liu L., Li Y. Amelioration of lipid abnormalities by alpha-lipoic acid through antioxidative and anti-inflammatory effects. Obesity Silver Spring 2011, 198:1647-1653.