메뉴 건너뛰기




Volumn 49, Issue 4, 2011, Pages 983-990

Embryonic exposure to octylphenol induces changes in testosterone levels and disrupts reproductive efficiency in rats at their adulthood

Author keywords

Male reproduction; Octylphenol; Pre and post implantation losses; Serum testosterone; Sperm; Steroidogenic marker enzymes

Indexed keywords

3(OR 17)BETA HYDROXYSTEROID DEHYDROGENASE; FOLLITROPIN; HYDROXYSTEROID DEHYDROGENASE; LUTEINIZING HORMONE; MESSENGER RNA; OCTYLPHENOL; PHENOL DERIVATIVE; STEROIDOGENIC ACUTE REGULATORY PROTEIN; TESTOSTERONE; TESTOSTERONE 17BETA DEHYDROGENASE; UNCLASSIFIED DRUG;

EID: 79952450903     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fct.2011.01.004     Document Type: Article
Times cited : (8)

References (66)
  • 1
    • 33748433508 scopus 로고    scopus 로고
    • Effects of maternal 4-tert-octylphenol exposure on the reproductive tract of male rats at adulthood
    • Aydogan M., Barlas N. Effects of maternal 4-tert-octylphenol exposure on the reproductive tract of male rats at adulthood. Reprod. Toxicol. 2006, 22:455-460.
    • (2006) Reprod. Toxicol. , vol.22 , pp. 455-460
    • Aydogan, M.1    Barlas, N.2
  • 3
    • 0001062124 scopus 로고
    • Methods of enzymatic analysis
    • Academic Press, New York, H.U. Bergmayer (Ed.)
    • Bergmayer H.U. Methods of enzymatic analysis. Verlag Chemie Weinheim 1974, 447-489. Academic Press, New York. H.U. Bergmayer (Ed.).
    • (1974) Verlag Chemie Weinheim , pp. 447-489
    • Bergmayer, H.U.1
  • 4
    • 33745194112 scopus 로고    scopus 로고
    • The toxic effect of 4-tertoctylphenol on the reproductive system of male rat
    • Bian Q., Qian J., Xu L., Chen J., Song L., Wang X. The toxic effect of 4-tertoctylphenol on the reproductive system of male rat. Food Chem. Toxicol. 2006, 44:1355-1361.
    • (2006) Food Chem. Toxicol. , vol.44 , pp. 1355-1361
    • Bian, Q.1    Qian, J.2    Xu, L.3    Chen, J.4    Song, L.5    Wang, X.6
  • 5
    • 0028990274 scopus 로고
    • Concentrations of alkylphenols in rivers and estuaries in England and Wales
    • Blackburn M.A., Waldock M.J. Concentrations of alkylphenols in rivers and estuaries in England and Wales. Water Res. 1995, 29:1623-1629.
    • (1995) Water Res. , vol.29 , pp. 1623-1629
    • Blackburn, M.A.1    Waldock, M.J.2
  • 6
    • 0030794963 scopus 로고    scopus 로고
    • Chronic administration of the environmental pollutant 4-tert-octylphenol to adult male rats interferes with the secretion of luteinizing hormone, follicle-stimulating hormone, prolactin, and testosterone
    • Blake C.A., Boockfor F.R. Chronic administration of the environmental pollutant 4-tert-octylphenol to adult male rats interferes with the secretion of luteinizing hormone, follicle-stimulating hormone, prolactin, and testosterone. Biol. Reprod. 1997, 57:255-266.
    • (1997) Biol. Reprod. , vol.57 , pp. 255-266
    • Blake, C.A.1    Boockfor, F.R.2
  • 7
    • 0842307059 scopus 로고    scopus 로고
    • Effects of 4-tert-octylphenol given in drinking water for 4 months on the male reproductive system of Fischer 344 rats
    • Blake C.A., Boockfor F.R., Nair-Menon J.U., Millette F.C., Raychoundhury S.S., McCoy G.L. Effects of 4-tert-octylphenol given in drinking water for 4 months on the male reproductive system of Fischer 344 rats. Reprod. Toxicol. 2004, 18:43-51.
    • (2004) Reprod. Toxicol. , vol.18 , pp. 43-51
    • Blake, C.A.1    Boockfor, F.R.2    Nair-Menon, J.U.3    Millette, F.C.4    Raychoundhury, S.S.5    McCoy, G.L.6
  • 8
    • 0030768008 scopus 로고    scopus 로고
    • Chronic administration of 4-tert-octylphenol to adult male rats causes shrinkage of the testes and male accessory sex organs, distrupts spermatogenesis, and increases the incidence of sperm deformities
    • Boockfor F.R., Blake C.A. Chronic administration of 4-tert-octylphenol to adult male rats causes shrinkage of the testes and male accessory sex organs, distrupts spermatogenesis, and increases the incidence of sperm deformities. Biol. Reprod. 1997, 57:267-277.
    • (1997) Biol. Reprod. , vol.57 , pp. 267-277
    • Boockfor, F.R.1    Blake, C.A.2
  • 10
    • 24944477515 scopus 로고    scopus 로고
    • Effects of endocrine disrupters on the oocytes and embryos o farm animals
    • Brevini A., Cillo F., Antonini S., Gandolfi F. Effects of endocrine disrupters on the oocytes and embryos o farm animals. Reprod. Domest. Anim. 2005, 40:291-299.
    • (2005) Reprod. Domest. Anim. , vol.40 , pp. 291-299
    • Brevini, A.1    Cillo, F.2    Antonini, S.3    Gandolfi, F.4
  • 11
    • 0032129112 scopus 로고    scopus 로고
    • Reproductive endpoints in general toxicity studies: are they predictive?
    • Chapin R.E., Sloane R.A., Haseman J.K. Reproductive endpoints in general toxicity studies: are they predictive?. Reprod. Toxicol. 1998, 12:489-494.
    • (1998) Reprod. Toxicol. , vol.12 , pp. 489-494
    • Chapin, R.E.1    Sloane, R.A.2    Haseman, J.K.3
  • 12
    • 0027428381 scopus 로고
    • Developmental effects of endocrine-disrupting chemical in wildlife and humans
    • Colborn T., Vom Saal F.S., Soto A.M. Developmental effects of endocrine-disrupting chemical in wildlife and humans. Environ. Health Perspect. 1993, 101:378-384.
    • (1993) Environ. Health Perspect. , vol.101 , pp. 378-384
    • Colborn, T.1    Vom Saal, F.S.2    Soto, A.M.3
  • 13
    • 0002752419 scopus 로고
    • Monitoring of the estrous cycle in the laboratory rodent by vaginal lavage
    • Academic Press, San Diego, J.J. Heindel, R.E. Chapin (Eds.)
    • Cooper R.L., Goldman J.M., Vandenbergh J.G. Monitoring of the estrous cycle in the laboratory rodent by vaginal lavage. Methods in Toxicology: Female Reproductive Toxicology 1993, 45-56. Academic Press, San Diego. J.J. Heindel, R.E. Chapin (Eds.).
    • (1993) Methods in Toxicology: Female Reproductive Toxicology , pp. 45-56
    • Cooper, R.L.1    Goldman, J.M.2    Vandenbergh, J.G.3
  • 14
    • 0041523906 scopus 로고    scopus 로고
    • CPCSEA CPCSEA guidelines for laboratory animal facility
    • CPCSEA CPCSEA guidelines for laboratory animal facility. Indian J. Pharmacol. 2003, 35:257-274.
    • (2003) Indian J. Pharmacol. , vol.35 , pp. 257-274
  • 17
    • 0027487124 scopus 로고
    • Surface and surface-to-volume relationships of the Sertoli cell during the cycle of the seminiferous epithelium in the rat
    • de Franca L.R., Ghosh S., Ye S.J., Russell L.D. Surface and surface-to-volume relationships of the Sertoli cell during the cycle of the seminiferous epithelium in the rat. Biol. Reprod. 1993, 49:1215-1228.
    • (1993) Biol. Reprod. , vol.49 , pp. 1215-1228
    • de Franca, L.R.1    Ghosh, S.2    Ye, S.J.3    Russell, L.D.4
  • 19
    • 0038575340 scopus 로고    scopus 로고
    • Human 'testicular dysgenesis syndrome': a possible model based on in utero exposure of the rat to dibutyl phthalate
    • Fisher J.S., Macpherson S., Marchetti N., Sharpe R.M. Human 'testicular dysgenesis syndrome': a possible model based on in utero exposure of the rat to dibutyl phthalate. Hum. Reprod. 2003, 18:1383-1394.
    • (2003) Hum. Reprod. , vol.18 , pp. 1383-1394
    • Fisher, J.S.1    Macpherson, S.2    Marchetti, N.3    Sharpe, R.M.4
  • 20
    • 0035681994 scopus 로고    scopus 로고
    • Wildlife as sentinels of human health effects in the Great Lakes-St. Lawrence basin
    • Fox G.A. Wildlife as sentinels of human health effects in the Great Lakes-St. Lawrence basin. Environ. Health Perspect. 2001, 109:853-861.
    • (2001) Environ. Health Perspect. , vol.109 , pp. 853-861
    • Fox, G.A.1
  • 21
    • 43049153241 scopus 로고    scopus 로고
    • Developmental programming and endocrine disruptor effects on reproductive neuroendocrine systems
    • Gore A.C. Developmental programming and endocrine disruptor effects on reproductive neuroendocrine systems. Front. Neuroendocrinol. 2008, 29:358-374.
    • (2008) Front. Neuroendocrinol. , vol.29 , pp. 358-374
    • Gore, A.C.1
  • 22
    • 77956127888 scopus 로고
    • The preparation of 125I labeled human growth hormone of high specific radioactivity
    • Greenwood F.C., Hunter W.M., Clover J.S. The preparation of 125I labeled human growth hormone of high specific radioactivity. Biochem. J. 1963, 89:114-123.
    • (1963) Biochem. J. , vol.89 , pp. 114-123
    • Greenwood, F.C.1    Hunter, W.M.2    Clover, J.S.3
  • 23
    • 0242318890 scopus 로고    scopus 로고
    • Effects of 4-tert-octylphenol, 4-tert-butylphenol, and dietylstilbestrol on prenatal testosterone surge in the rat
    • Haavisto T.E., Adamsson N.A., Myllymaki S.A., Toppari J., Paranko J. Effects of 4-tert-octylphenol, 4-tert-butylphenol, and dietylstilbestrol on prenatal testosterone surge in the rat. Reprod. Toxicol. 2003, 17:593-605.
    • (2003) Reprod. Toxicol. , vol.17 , pp. 593-605
    • Haavisto, T.E.1    Adamsson, N.A.2    Myllymaki, S.A.3    Toppari, J.4    Paranko, J.5
  • 24
    • 0035798830 scopus 로고    scopus 로고
    • Effects of 4-tert-octylphenol on initiation and maintenance of pregnancy following oral administration during early pregnancy in rats
    • Harazono A., Ema M. Effects of 4-tert-octylphenol on initiation and maintenance of pregnancy following oral administration during early pregnancy in rats. Toxicol. Lett. 2001, 119:79-84.
    • (2001) Toxicol. Lett. , vol.119 , pp. 79-84
    • Harazono, A.1    Ema, M.2
  • 26
    • 0345707679 scopus 로고    scopus 로고
    • Maternal-fetal transfer of endocrine distruptors in the induction of Calbindin-D9k mRNA and protein during pregnancy in rat model
    • Hong E.-J., Choi K.-C., Jeung E.-B. Maternal-fetal transfer of endocrine distruptors in the induction of Calbindin-D9k mRNA and protein during pregnancy in rat model. Mol. Cell Endocrinol. 2003, 212:63-72.
    • (2003) Mol. Cell Endocrinol. , vol.212 , pp. 63-72
    • Hong, E.-J.1    Choi, K.-C.2    Jeung, E.-B.3
  • 27
    • 3042526292 scopus 로고    scopus 로고
    • Transfer of maternally injected endocrine disruptors through breast milk during lactation induces neonatal Calbindin-D9k in the rat model
    • Hong E.J., Choi K.C., Jung Y.W., Leung P.C.K., Jeung E.B. Transfer of maternally injected endocrine disruptors through breast milk during lactation induces neonatal Calbindin-D9k in the rat model. Reoprod. Toxicol. 2004, 18:661-668.
    • (2004) Reoprod. Toxicol. , vol.18 , pp. 661-668
    • Hong, E.J.1    Choi, K.C.2    Jung, Y.W.3    Leung, P.C.K.4    Jeung, E.B.5
  • 29
    • 0027411946 scopus 로고
    • Transcriptional regulation of human genes for steroidogenic enzymes
    • Hum D.W., Miller W.L. Transcriptional regulation of human genes for steroidogenic enzymes. Clinical Chem. 1993, 39:333-340.
    • (1993) Clinical Chem. , vol.39 , pp. 333-340
    • Hum, D.W.1    Miller, W.L.2
  • 30
    • 0033802043 scopus 로고    scopus 로고
    • Male reproductive health: a cause for concern?
    • Irvine D. Male reproductive health: a cause for concern?. Andrologia 2000, 32:195-208.
    • (2000) Andrologia , vol.32 , pp. 195-208
    • Irvine, D.1
  • 31
    • 0035866691 scopus 로고    scopus 로고
    • Distribution and behaviour of nonylphenol, octylphenol, and nonylphenol monoethoxylate in Tokyo metropolitan area: their association with aquatic particles and sedimentary distributions
    • Isobe T., Nishiyama H., Nakashima A., Takada H. Distribution and behaviour of nonylphenol, octylphenol, and nonylphenol monoethoxylate in Tokyo metropolitan area: their association with aquatic particles and sedimentary distributions. Environ. Sci. Technol. 2001, 35:1041-1049.
    • (2001) Environ. Sci. Technol. , vol.35 , pp. 1041-1049
    • Isobe, T.1    Nishiyama, H.2    Nakashima, A.3    Takada, H.4
  • 33
    • 0029146597 scopus 로고
    • A variety of environmentally persistent chemicals, including some phthalate plasticizers, are weakly estrogenic
    • Jobling S., Reynolds T., White R., Parker M.G., Sumpter J.P. A variety of environmentally persistent chemicals, including some phthalate plasticizers, are weakly estrogenic. Environ. Health Perspect. 1995, 103:582-587.
    • (1995) Environ. Health Perspect. , vol.103 , pp. 582-587
    • Jobling, S.1    Reynolds, T.2    White, R.3    Parker, M.G.4    Sumpter, J.P.5
  • 34
    • 34548721038 scopus 로고    scopus 로고
    • Octylphenol reduces the expressions of steroidogenic enzymes and testosterone production in mouse testis
    • Kim S.K., Kim J.H., Lee H.J., Yoon Y.D. Octylphenol reduces the expressions of steroidogenic enzymes and testosterone production in mouse testis. Environ. Toxicol. 2007, 22:449-458.
    • (2007) Environ. Toxicol. , vol.22 , pp. 449-458
    • Kim, S.K.1    Kim, J.H.2    Lee, H.J.3    Yoon, Y.D.4
  • 35
    • 62549165138 scopus 로고    scopus 로고
    • Alteration of testicular steroidogenesis and histopathology of reproductive system in male rats treated with triclosan
    • Kumar V., Chakraborty A., Raj Kural M., Roy P. Alteration of testicular steroidogenesis and histopathology of reproductive system in male rats treated with triclosan. Reprod. Toxicol. 2008, 27:177-185.
    • (2008) Reprod. Toxicol. , vol.27 , pp. 177-185
    • Kumar, V.1    Chakraborty, A.2    Raj Kural, M.3    Roy, P.4
  • 36
    • 0032814061 scopus 로고    scopus 로고
    • Developmental toxicity evaluation of rats dosed orally or cutaneously with octoxynol-9
    • Leung H.-W., Ballantyne B. Developmental toxicity evaluation of rats dosed orally or cutaneously with octoxynol-9. J. Appl. Toxicol. 1999, 19:267-273.
    • (1999) J. Appl. Toxicol. , vol.19 , pp. 267-273
    • Leung, H.-W.1    Ballantyne, B.2
  • 37
    • 0023712119 scopus 로고
    • Inhibition of ovulation, steroidogenesis and collagenolytic activity in rabbits by sulphide induced hyperprolactinemia
    • Lin K.C., Kawamura N., Okumura H., Mori T. Inhibition of ovulation, steroidogenesis and collagenolytic activity in rabbits by sulphide induced hyperprolactinemia. J. Reprod. Fertil. 1988, 83:611-618.
    • (1988) J. Reprod. Fertil. , vol.83 , pp. 611-618
    • Lin, K.C.1    Kawamura, N.2    Okumura, H.3    Mori, T.4
  • 39
    • 0029927847 scopus 로고    scopus 로고
    • Expression of cytochrome P450 17alpha-hydroxylase/C17-20 lyase in the fetal rat testis is reduced by maternal exposure to exogenous estrogens
    • Majdic G., Sharpe R.M., O'Shaughnessy P.J., Saunders P.T. Expression of cytochrome P450 17alpha-hydroxylase/C17-20 lyase in the fetal rat testis is reduced by maternal exposure to exogenous estrogens. Endocrinology 1996, 137:1063-1070.
    • (1996) Endocrinology , vol.137 , pp. 1063-1070
    • Majdic, G.1    Sharpe, R.M.2    O'Shaughnessy, P.J.3    Saunders, P.T.4
  • 40
    • 0031002166 scopus 로고    scopus 로고
    • Maternal oestrogen/xenoestrogen exposure alters expression of steroidogenic factor-1(SF-1/Ad4BP) in fetal rat testis
    • Majdic G., Sharpe R.M., Saunders P.T.K. Maternal oestrogen/xenoestrogen exposure alters expression of steroidogenic factor-1(SF-1/Ad4BP) in fetal rat testis. Mol. Cell Endocrinol. 1997, 127:91-98.
    • (1997) Mol. Cell Endocrinol. , vol.127 , pp. 91-98
    • Majdic, G.1    Sharpe, R.M.2    Saunders, P.T.K.3
  • 41
    • 79952440028 scopus 로고
    • Secretory function of the prostate, seminal vesicle, and other male accessory organs of testis
    • Mann T. Secretory function of the prostate, seminal vesicle, and other male accessory organs of testis. Andrologia 1974, 52:12-17.
    • (1974) Andrologia , vol.52 , pp. 12-17
    • Mann, T.1
  • 42
  • 43
    • 3242879161 scopus 로고    scopus 로고
    • Sertoli-Sertoli and Sertoli-germ cell interactions and their significance in germ cell movement in the seminiferous epithelium during spermatogenesis
    • Mruk D.D., Cheng C.Y. Sertoli-Sertoli and Sertoli-germ cell interactions and their significance in germ cell movement in the seminiferous epithelium during spermatogenesis. Endocrinol. Rev. 2004, 25:747-806.
    • (2004) Endocrinol. Rev. , vol.25 , pp. 747-806
    • Mruk, D.D.1    Cheng, C.Y.2
  • 44
    • 0035661757 scopus 로고    scopus 로고
    • Reproductive effects in male and female rats of neonatal exposure to p-octylphenol
    • Nagao T., Yoshimura S., Saito Y., Nakagomi M., Usumi K., Ono H. Reproductive effects in male and female rats of neonatal exposure to p-octylphenol. Reprod. Toxicol. 2001, 15:682-693.
    • (2001) Reprod. Toxicol. , vol.15 , pp. 682-693
    • Nagao, T.1    Yoshimura, S.2    Saito, Y.3    Nakagomi, M.4    Usumi, K.5    Ono, H.6
  • 45
    • 1642324507 scopus 로고    scopus 로고
    • Alterations of gene expression in adult male rat testis and pituitary shortly after sub acute administration of the antiandrogen flutmide
    • Ohsako S., Kubota K., Kurosawa S., Takeda K., Qing W., Ishimura R., Tohyma C. Alterations of gene expression in adult male rat testis and pituitary shortly after sub acute administration of the antiandrogen flutmide. J. Reprod. Dev. 2003, 49:275-290.
    • (2003) J. Reprod. Dev. , vol.49 , pp. 275-290
    • Ohsako, S.1    Kubota, K.2    Kurosawa, S.3    Takeda, K.4    Qing, W.5    Ishimura, R.6    Tohyma, C.7
  • 48
    • 0025670608 scopus 로고
    • Effect of constant infusion of gonadotropin releasing hormone (GnRH) agonist buserelin and antagonist CDB 2085 A using osmotic mini pumps on testicular function in adult male bonnet monkey (Macaca radiata)
    • Rao A.J., Chakraborti R., Kotagi S.G., Ravindranath N. Effect of constant infusion of gonadotropin releasing hormone (GnRH) agonist buserelin and antagonist CDB 2085 A using osmotic mini pumps on testicular function in adult male bonnet monkey (Macaca radiata). Andrologia 1990, 22:567-573.
    • (1990) Andrologia , vol.22 , pp. 567-573
    • Rao, A.J.1    Chakraborti, R.2    Kotagi, S.G.3    Ravindranath, N.4
  • 49
    • 33748427088 scopus 로고    scopus 로고
    • Researchers identify octylphenol as human endocrine disrupter
    • Scott A. Researchers identify octylphenol as human endocrine disrupter. Chem Week. 2000, 162:13.
    • (2000) Chem Week. , vol.162 , pp. 13
    • Scott, A.1
  • 50
    • 0035977842 scopus 로고    scopus 로고
    • Hormones and testis development and the possible adverse effects of environmental chemicals
    • Sharpe R.M. Hormones and testis development and the possible adverse effects of environmental chemicals. Toxicol. Lett. 2001, 120:221-232.
    • (2001) Toxicol. Lett. , vol.120 , pp. 221-232
    • Sharpe, R.M.1
  • 52
    • 0035004535 scopus 로고    scopus 로고
    • Testicular dysgenesis syndrome: an increasingly common developmental disorder with environmental aspects
    • Skakkebaek N.E., Rajpert-De Meyts E., Main K.M. Testicular dysgenesis syndrome: an increasingly common developmental disorder with environmental aspects. Hum. Reprod. 2001, 16:972-978.
    • (2001) Hum. Reprod. , vol.16 , pp. 972-978
    • Skakkebaek, N.E.1    Rajpert-De Meyts, E.2    Main, K.M.3
  • 53
    • 0026089986 scopus 로고
    • Cell-cell interactions in the testes
    • Skinner M.K. Cell-cell interactions in the testes. Endocrinol. Rev. 1991, 12:45-77.
    • (1991) Endocrinol. Rev. , vol.12 , pp. 45-77
    • Skinner, M.K.1
  • 54
    • 0014970549 scopus 로고
    • Hormonal control of mammalian spermatogenesis
    • Steinberger E. Hormonal control of mammalian spermatogenesis. Physiol. Rev 1971, 51:1-22.
    • (1971) Physiol. Rev , vol.51 , pp. 1-22
    • Steinberger, E.1
  • 55
    • 0032576482 scopus 로고    scopus 로고
    • Xenoendorine disrupters: environmental impacts
    • Sumpter J.P. Xenoendorine disrupters: environmental impacts. Toxicol. Lett. 1998, 28:337-342.
    • (1998) Toxicol. Lett. , vol.28 , pp. 337-342
    • Sumpter, J.P.1
  • 56
    • 0019526424 scopus 로고
    • A triple stain technique for evaluating normal acrosome reaction of human sperm
    • Talbot P., Chacon R.S. A triple stain technique for evaluating normal acrosome reaction of human sperm. J. Exp. Zool. 1981, 215:201-208.
    • (1981) J. Exp. Zool. , vol.215 , pp. 201-208
    • Talbot, P.1    Chacon, R.S.2
  • 57
    • 0142246318 scopus 로고    scopus 로고
    • Analysis of selected pesticides and alkylphenols in human cord blood by gas chromatograph-mass spectrometer
    • Tan B.L.L., Mohd M.A. Analysis of selected pesticides and alkylphenols in human cord blood by gas chromatograph-mass spectrometer. Talanta 2003, 6:385-391.
    • (2003) Talanta , vol.6 , pp. 385-391
    • Tan, B.L.L.1    Mohd, M.A.2
  • 59
    • 0035093337 scopus 로고    scopus 로고
    • Evaluation of 4-nonylphenols and 4-tert-octylphenol contamination of fish in rivers by laboratory accumulation and excretion experiments
    • Tsuda T., Takino A., Muraki K., Harada H., Kojima M. Evaluation of 4-nonylphenols and 4-tert-octylphenol contamination of fish in rivers by laboratory accumulation and excretion experiments. Water Res. 2001, 35:1786-1792.
    • (2001) Water Res. , vol.35 , pp. 1786-1792
    • Tsuda, T.1    Takino, A.2    Muraki, K.3    Harada, H.4    Kojima, M.5
  • 60
    • 0015320909 scopus 로고
    • Evidence for a specific seminiferous tubular factor affecting follicle-stimulating hormone secretion in man
    • Van Thiel D.H., Sherins R.J., Myers G.H., de Vita V.T. Evidence for a specific seminiferous tubular factor affecting follicle-stimulating hormone secretion in man. J. Clin. Invest. 1972, 51:1009-1019.
    • (1972) J. Clin. Invest. , vol.51 , pp. 1009-1019
    • Van Thiel, D.H.1    Sherins, R.J.2    Myers, G.H.3    de Vita, V.T.4
  • 61
    • 0028233813 scopus 로고
    • Environmentally persistent alkylphenolic compounds are estrogenic
    • White R., Jobling S., Hoare S., Sumpter J., Parker M. Environmentally persistent alkylphenolic compounds are estrogenic. Endocrinology 1994, 135:178-182.
    • (1994) Endocrinology , vol.135 , pp. 178-182
    • White, R.1    Jobling, S.2    Hoare, S.3    Sumpter, J.4    Parker, M.5
  • 62
    • 79952441495 scopus 로고    scopus 로고
    • WHO, Global assessment of the state-of-the-science of endocrine disruptors. WHO/PCS/EDC/02.2. Geneva, 2002 (accessed 19.12.08).
    • WHO, 2002. Global assessment of the state-of-the-science of endocrine disruptors. WHO/PCS/EDC/02.2. Geneva, 2002 (accessed 19.12.08).
    • (2002)
  • 63
    • 0036973956 scopus 로고    scopus 로고
    • Endocrine disruptors: can biological effects and environmental risks be predicted?
    • Witorsch R.J. Endocrine disruptors: can biological effects and environmental risks be predicted?. Regul. Toxicol. Pharmacol. 2002, 36:118-130.
    • (2002) Regul. Toxicol. Pharmacol. , vol.36 , pp. 118-130
    • Witorsch, R.J.1
  • 64
    • 0036635428 scopus 로고    scopus 로고
    • Environmental fate of alkylphenols and alkylphenol ethoxylates - a review
    • Ying G.G., Williams B., Kookana R. Environmental fate of alkylphenols and alkylphenol ethoxylates - a review. Environ. Int. 2002, 28:215-226.
    • (2002) Environ. Int. , vol.28 , pp. 215-226
    • Ying, G.G.1    Williams, B.2    Kookana, R.3
  • 65
    • 0035826511 scopus 로고    scopus 로고
    • Effects of neonatal exposure to a high-dose p-tert-octylphenol on the male reproductive tract in rats
    • Yoshida M., Katsuda S., Takenaka A., Watanabe G., Taya K., Maekawa A. Effects of neonatal exposure to a high-dose p-tert-octylphenol on the male reproductive tract in rats. Toxicol. Lett. 2001, 121:21-33.
    • (2001) Toxicol. Lett. , vol.121 , pp. 21-33
    • Yoshida, M.1    Katsuda, S.2    Takenaka, A.3    Watanabe, G.4    Taya, K.5    Maekawa, A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.