Chronic administration of the environmental pollutant 4-Tert-octylphenol to adult male rats interferes with the secretion of luteinizing hormone, follicle-stimulating hormone, prolactin, and testosterone

Biology of Reproduction

Volumn 57, Issue 2, 1997, Pages 255-266

  Blake, Charles A ^a   Boockfor, Fredric R ^a  

^a UNIVERSITY OF SOUTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 TERT OCTYLPHENOL; ESTROGEN; FOLLITROPIN; LUTEINIZING HORMONE; PHENOL DERIVATIVE; PROLACTIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; ESTROGEN BLOOD LEVEL; FOLLITROPIN BLOOD LEVEL; HORMONE RELEASE; LUTEINIZING HORMONE BLOOD LEVEL; MAMMAL CELL; NONHUMAN; ORCHIECTOMY; POLLUTANT; PRIORITY JOURNAL; PROLACTIN BLOOD LEVEL; QUALITATIVE DIAGNOSIS; TESTOSTERONE BLOOD LEVEL;

ANIMALS; BODY WEIGHT; EATING; ENVIRONMENTAL POLLUTANTS; ESTRADIOL; FOLLICLE STIMULATING HORMONE; HEMATOCRIT; LUTEINIZING HORMONE; MALE; ORCHIECTOMY; ORGAN SIZE; PHENOLS; PITUITARY GLAND, ANTERIOR; PROLACTIN; RATS; RATS, INBRED F344; SURFACE-ACTIVE AGENTS; TESTOSTERONE;

ANIMALIA; MAMMALIA; VERTEBRATA; ZEA MAYS;

EID: 0030794963     PISSN: 00063363     EISSN: None     Source Type: Journal    
DOI: 10.1095/biolreprod57.2.255     Document Type: Article

References (50)

1. Weinberger P, Rea MS. Effects of aminocarb and its formulation adjuncts on the growth of Chlorella pyrenoidosa chick. Environ Exp Bot 1982; 22:491-496.
2. Rantuccio F, Sinisi D, Coviello C, Conte A, Scardigno A. Histological changes in rabbits after application of medicaments and cosmetic bases (III). Contact Dermatitis 1984; 10:212-219.
3. Lowenheim FA, Moran MK. p-nonylphenol. In: Faith, Keyes, and Clark's Industrial Chemicals. 4th Edition. New York: John Wiley & Sons; 1975: 575-578.
4. Synthetic Organic Chemicals, United States Production and Sales, 1990, USITC Publication 2470; December 1991; Washington, DC: US International Trade Commission.
5. Scharer DH, Kravetz L, Carr JB. Biodegradation of nonionic surfactants. Tappi 1979; 62:75-78.
6. Stephanou E, Giger W. Persistent organic chemicals in sewage effluents. 2. quantitative determinations of nonylphenols and nonylphenol ethoxylates by glass capillary gas chromatography. Environ Sci Technol 1982; 16:800-805.
7. Reinhard M, Goodman N, Mortelmans KE. Occurrence of brominated alkylphenol polyethoxy carboxylates in mutagenic waste water concentrates. Environ Sci Technol 1982; 16:351-362.
8. Giger W, Brunner PH, Schaffner C, 4-nonylphenol in sewage sludge: accumulation of toxic metabolites from nonionic surfactants. Science 1984; 225:623-625.
9. Giger W, Ahel M, Koch M, Laubscher HU, Schaffner C, Schneider J. Behaviour of alkylphenol polyethoxy late surfactants and of nitrilotriacetate in sewage treatment. Water Sci Technol 1987; 19:449-460.
10. Gaffney PE. Carpet and rug industry case study II: biological effects. J Water Pollut Control Fed 1976; 48:2731-2737.
11. Sundaram KMS, Szeto S. The dissipation of nonylphenol in stream and pond water under simulated field conditions. J Environ Sci Health 1981; 16:767-776.
12. Ikeda M, Ohtsuji H, Miyahara S. Two cases of leucoderma presumably due to nonyl- or octylphenol in synthetic detergents. Ind Health 1970; 8:192-196.
13. Junk GA, Svec HJ, Vick RD, A very MJ. Contamination of water by synthetic polymer tubes. Environ Sci Toxicol 1974; 8:1100-1106.
14. Soto AM, Justicia H, Wray JW, Sonnenschein C. p-nonyl-phenol: an estrogenic xenobiotic released from "modified" polystyrene. Environ Health Perspect 1991; 92:167-173.
15. Knaak JB, Eldridge JM, Sullivan LJ. Excretion of certain polyethylene glycol ether adducts of nonylphenol by the rat. Toxicol Appl Pharmacol 1966; 9:331-340.
16. McLeese DW, Zitko V, Sergeant DB, Burridge L, Metcalfe CD. Lethality and accumulation of alkylphenols in aquatic fauna. Chemosphere 1981; 10:723-730.
17. Shiraishi H, Carter DS, Hites RA. Identification and determination of tert-alkylphenols in carp from the Trenton Channel of the Detroit River, Michigan, USA. Biomed Environ Mass Spectrom 1989; 18:478-483.
18. Nair-Menon JU, Campbell GT, Blake CA. Toxic effects of octylphenol on cultured rat and murine splenocytes. Toxicol Appl Pharmacol 1996; 139:437-444.
19. Mueller GC, Kim U-H. Displacement of estradiol from estrogen receptors by simple alkyl phenols. Endocrinology 1978; 102:1429-1435.
20. Soto AM, Lin T-M, Justicia H, Silvia RM, Sonnenschein C. An "in culture" bioassay to assess the estrogenicity of xenobiotics (E-Screen). In: Colborn T, Clement C (eds.), Advances in Modern Environmental Toxicology. Chemically-Induced Alterations in Sexual and Functional Development: The Wildlife/Human Connection. Princeton, NJ: Princeton Scientific; 1992; 21: 295-309.
21. Jobling S, Sumpter JP. Detergent components in sewage effluent are weakly oestrogenic to fish: an in vitro study using rainbow trout (Oncorhynchus mykiss) hepatocytes. Aquatic Toxicol 1993; 27:361-372.
22. White R, Jobling S, Hoare SA, Sumpter JP, Parker MG. Environmentally persistent alkylphenolic compounds are estrogenic. Endocrinology 1994; 135:175-182.
23. Davis DL, Bradlow HL. Can environmental estrogens cause breast cancer? Sci Am 1995; 273:166-172.
24. Sharpe RM, Skakkebaek NE. Are oestrogens involved in falling sperm counts and disorders of the male reproductive tract? The Lancet 1993; 341:1392-1395.
25. Rodale R. Tiptoe through the toxic tulips. Org Gardening Farming 1976; 23:52-56.
26. Arnold SF, Klotz DM, Collins BM, Vonier PM, Guillette LJ Jr, McLachlan JA. Synergistic activation of estrogen receptor with combinations of environmental chemicals. Science 1996; 272:1489-1492.
27. Ramamoorthy K, Wang F, Chen I-C, Safe S, Norris JD, McDonnell DP, Gaido KW, Bocchinfuso WP, Korach KS. Potency of combined estrogenic pesticides. Science 1997; 275:405.
28. Shaikh AA. Estrone and estradiol levels in the ovarian venous blood from rats during the estrous cycle and pregnancy. Biol Reprod 1971; 5:297-307.
29. Kalra PS, Fawcett CP, Krulich L, McCann SM. The effect of gonadal steroids on plasma gonadotropins and prolactin in the rat. Endocrinology 1973; 92:1256-1268.
30. Kalra SP, Kalra PS. Neural regulation of luteinizing hormone secretion in the rat. Endocr Rev 1983; 4:311-351.
31. McLeod RM. Regulation of prolactin secretion. In: Martini L, Ganong WF (eds.), Frontiers in Neuroendocrinology. New York: Raven Press; 1976: 4:169-194.
32. 131I. Proc Soc Exp Biol Med 1968; 128:807-811.
33. Boockfor FR, Blake CA. The alkylphenol, octylphenol, impairs mammalian germ cell production and storage. In: Program of the 35th annual meeting of the American Society for Cell Biology; 1995; Washington, DC. Abstract 2487.
34. Dukes PP, Goldwasser E. Inhibition of erythropoiesis by estrogens. Endocrinology 1961; 69:21-29.
35. Rodriguez-Sierra JF, Sridaran R, Blake CA. Monosodium glutamate disruption of behavioral and endocrine function in the female rat. Neuroendocrinology 1980; 31:228-235.
36. Olson DR, Blake CA. Basal luteinizing hormone and follicle-stimulating hormone release rates as a function of time after castration in female and male rats. Neuroendocrinology 1991; 53:124-133.
37. Blake CA. Paradoxical effects of drugs acting on the central nervous system on the preovulatory release of pituitary luteinizing hormone in pro-oestrous rats. J Endocrinol 1978; 79:319-326.
38. Neill JD. Effect of "stress" on serum prolactin and luteinizing hormone levels during the estrous cycle of the rat. Endocrinology 1970; 87:1192-1197.
39. Terkel J, Blake CA, Sawyer CH. Serum prolactin levels in lactating rats after suckling or exposure to ether. Endocrinology 1972; 91:49-53.
40. Siiteri PK, Febres F. Ovarian hormone synthesis, circulation, and mechanisms of action. In: DeGroot LJ, Cahill GF Jr, Martini L, Nelson DH, Odell WD, Potts JT Jr, Steinberger E, Winegrad AI (eds.), Endocrinology. New York: Grune & Stratum; 1979; 3: 1401-1417.
41. Elias KA, Weiner RI. Direct arterial vascularization of estrogen-induced prolactin-secreting anterior pituitary tumors. Proc Natl Acad Sci USA 1984; 81:4549-4553.
42. Blake CA, Nair-Menon JU, Raychoudhury SS, Millette CH Bogovich K, Woller MJ, Lin T, Wang D, Boockfor FR, Campbell GT. Octylphenol causes death of cultured rat thymocytes, splenocytes, and cells from reproductive organs. In: Program of the 35th annual meeting of the American Society for Cell Biology; 1995; Washington, DC. Abstract 2067.
43. Boockfor FR, Blake CA. Exposure to the environmental pollutant, octylphenol, causes sperm deformities and shrinkage of the testes and male accessory sex organs. In: Program of the 6th International Congress on Cell Biology and the 36th annual meeting of the American Society for Cell Biology; 1996; San Francisco, CA. Abstract 729.
44. Boockfor FR, Blake CA, Chronic administration of 4-tert-octylphenol to adult male rats causes shrinkage of the testes and male accessory sex organs, disrupts spermatogenesis, and increases sperm deformities. Biol Reprod 1997; 57:267-277.
45. Ellis GB, Desjardins C. Male rats secrete luteinizing hormone and testosterone episodically. Endocrinology 1982; 110:1618-1627.
46. van Beurden WMO, Roodnat B, Mulder E, van der Molen HJ. Further characterization of the effects of hypophysectomy, FSH and estrogen on LH stimulation of testosterone production in Leydig cells isolated from immature rats. Steroids 1978; 31:83-98.
47. Hsueh AJW, Dufau ML, Catt KJ, Direct inhibitory effect of estrogen on Leydig cell function of hypophysectomized rats. Endocrinology 1978; 103:1096-1102.
48. Bartke A, Williams KIH, Dalterio S. Effects of estrogens on testicular testosterone production in vitro. Biol Reprod 1977; 17:645-649.
49. Majdic G, Sharpe RM, O'Shaughnessy PJ, Saunders PTK. Expression of cytochrome P450 17α-hydroxylase/C17-20 lyase in the fetal rat testis is reduced by maternal exposure to exogenous estrogens. Endocrinology 1996; 137:1063-1070.
50. Smyth HF Jr, Carpenter CP, Weil CS, Pozzani UC, Striegel JA, Nycum JS. Range-finding toxicity data: List VII. Am Ind Hyg Assoc J 1969; 30:470-476.