Suppression of TRIF-dependent signaling pathway of toll-like receptors by allyl isothiocyanate in RAW 264.7 macrophages

International Immunopharmacology

Volumn 13, Issue 4, 2012, Pages 403-407

  Kim, Soo Jung ^a   Park, Hye Jeong ^a   Shin, Hwa Jeong ^a   Shon, Dong Hwa ^b   Kim, Do Hyun ^c   Youn, Hyung Sun ^a  

^a Soonchunhyang University   (South Korea)

^b Korea Food Research Institute   (South Korea)

^c Taejon Christian International School   (South Korea)

Author keywords

Allyl isothiocyanate; Lipopolysaccharide; Polyinosinic polycytidylic acid; Toll like receptors; TRIF

Indexed keywords

ALLYL ISOTHIOCYANATE; CPG OLIGODEOXYNUCLEOTIDE; GAMMA INTERFERON INDUCIBLE PROTEIN 10; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERFERON REGULATORY FACTOR 3; LIPOPOLYSACCHARIDE; MACROPHAGE ACTIVATING LIPOPEPTIDE 2; POLYINOSINIC POLYCYTIDYLIC ACID; TOLL INTERLEUKIN 1 RECEPTORDOMAIN CONTAINING ADAPTER INDUCING INTERFERON BETA; TOLL LIKE RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING SITE; DRUG ACTIVITY; DRUG STRUCTURE; DRUG TARGETING; GENE EXPRESSION; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ADAPTOR PROTEINS, VESICULAR TRANSPORT; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CELL LINE; CHEMOKINE CXCL10; INTERFERON REGULATORY FACTOR-3; ISOTHIOCYANATES; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; NF-KAPPA B; POLY I-C; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTORS; TRANSCRIPTIONAL ACTIVATION;

EID: 84862188994     PISSN: 15675769     EISSN: 18781705     Source Type: Journal    
DOI: 10.1016/j.intimp.2012.05.017     Document Type: Article

References (31)

1. H. Kumar, T. Kawai, and S. Akira Pathogen recognition by the innate immune system Int Rev Immunol 30 2011 16 34
2. K. Takeda, and S. Akira Toll-like receptors in innate immunity Int Immunol 17 2005 1 14
3. S. Akira, S. Uematsu, and O. Takeuchi Pathogen recognition and innate immunity Cell 124 2006 783 801
4. K.A. Fitzgerald, S.M. McWhirter, K.L. Faia, D.C. Rowe, E. Latz, and D.T. Golenbock IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway Nat Immunol 4 2003 491 496
5. T. Kawai, O. Takeuchi, T. Fujita, J. Inoue, P.F. Muhlradt, and S. Sato Lipopolysaccharide stimulates the MyD88-independent pathway and results in activation of IFN-regulatory factor 3 and the expression of a subset of lipopolysaccharide-inducible genes J Immunol 167 2001 5887 5894
6. J.J. zGao, M.B. Filla, M.J. Fultz, S.N. Vogel, S.W. Russell, and W.J. Murphy Autocrine/paracrine IFN-alphabeta mediates the lipopolysaccharide-induced activation of transcription factor Stat1alpha in mouse macrophages: pivotal role of Stat1alpha in induction of the inducible nitric oxide synthase gene J Immunol 161 1998 4803 4810
7. H. Bjorkbacka, K.A. Fitzgerald, F. Huet, X. Li, J.A. Gregory, and M.A. Lee The induction of macrophage gene expression by LPS predominantly utilizes Myd88-independent signaling cascades Physiol Genomics 19 2004 319 330
8. N.R. Han, W. Park, J.Y. Um, H.M. Kim, and H.J. Jeong Allyl isothiocyanate regulates caspase-1/receptor interacting protein-2 expression Int Immunopharmacol 11 2011 525 528
9. Y. Zhang Allyl isothiocyanate as a cancer chemopreventive phytochemical Mol Nutr Food Res 54 2010 127 135
10. S.K. Srivastava, D. Xiao, K.L. Lew, P. Hershberger, D.M. Kokkinakis, and C.S. Johnson Allyl isothiocyanate, a constituent of cruciferous vegetables, inhibits growth of PC-3 human prostate cancer xenografts in vivo Carcinogenesis 24 2003 1665 1670
11. T. Smith, S.R. Musk, and I.T. Johnson Allyl isothiocyanate selectively kills undifferentiated HT29 cells in vitro and suppresses aberrant crypt foci in the colonic mucosa of rats Biochem Soc Trans 24 1996 381S
12. K. Ippoushi, H. Itou, K. Azuma, and H. Higashio Effect of naturally occurring organosulfur compounds on nitric oxide production in lipopolysaccharide-activated macrophages Life Sci 71 2002 411 419
13. H.S. Youn, S.I. Ahn, and B.Y. Lee Guggulsterone suppresses the activation of transcription factor IRF3 induced by TLR3 or TLR4 agonists Int Immunopharmacol 9 2009 108 112
14. S.I. Ahn, J.K. Lee, and H.S. Youn Inhibition of homodimerization of toll-like receptor 4 by 6-shogaol Mol Cells 27 2009 211 215
15. H.S. Youn, S.I. Saitoh, K. Miyake, and D.H. Hwang Inhibition of homodimerization of toll-like receptor 4 by curcumin Biochem Pharmacol 72 2006 62 69
16. R. Lin, C. Heylbroeck, P. Genin, P.M. Pitha, and J. Hiscott Essential role of interferon regulatory factor 3 in direct activation of RANTES chemokine transcription Mol Cell Biol 19 1999 959 966
17. S.L. Schafer, R. Lin, P.A. Moore, J. Hiscott, and P.M. Pitha Regulation of type I interferon gene expression by interferon regulatory factor-3 J Biol Chem 273 1998 2714 2720
18. H. Bjorkbacka, K.A. Fitzgerald, F. Huet, X. Li, J.A. Gregory, and M.A. Lee The induction of macrophage gene expression by LPS predominantly utilizes Myd88-independent signaling cascades Physiol Genomics 19 2004 319 330
19. H.S. Youn, J.Y. Lee, K.A. Fitzgerald, H.A. Young, S. Akira, and D.H. Hwang Specific inhibition of MyD88-independent signaling pathways of TLR3 and TLR4 by resveratrol: molecular targets are TBK1 and RIP1 in TRIF complex J Immunol 175 2005 3339 3346
20. H.S. Youn, J.Y. Lee, S.I. Saitoh, K. Miyake, K.W. Kang, and Y.J. Choi Suppression of MyD88- and TRIF-dependent signaling pathways of toll-like receptor by (-)-epigallocatechin-3-gallate, a polyphenol component of green tea Biochem Pharmacol 72 2006 850 859
21. S.J. Park, M.Y. Lee, B.S. Son, and H.S. Youn TBK1-targeted suppression of TRIF-dependent signaling pathway of toll-like receptors by 6-shogaol, an active component of ginger Biosci Biotechnol Biochem 73 2009 1474 1478
22. S.J. Park, and H.S. Youn Isoliquiritigenin suppresses the toll-interleukin-1 receptor domain-containing adapter inducing interferon-beta (TRIF)-dependent signaling pathway of toll-like receptors by targeting TBK1 J Agric Food Chem 58 2010 4701 4705
23. I.S. Shin, H. Masuda, and K. Naohide Bactericidal activity of wasabi (Wasabia japonica) against Helicobacter pylori Int J Food Microbiol 94 2004 255 261
24. F.B. Luciano, and R.A. Holley Enzymatic inhibition by allyl isothiocyanate and factors affecting its antimicrobial action against Escherichia coli O157:H7 Int J Food Microbiol 131 2009 240 245
25. P.V. Nielsen, and R. Rios Inhibition of fungal growth on bread by volatile components from spices and herbs, and the possible application in active packaging, with special emphasis on mustard essential oil Int J Food Microbiol 60 2000 219 229
26. C.M. Lin, J.F. Preston III, and C.I. Wei Antibacterial mechanism of allyl isothiocyanate J Food Prot 63 2000 727 734
27. D. Xiao, S.K. Srivastava, K.L. Lew, Y. Zeng, P. Hershberger, and C.S. Johnson Allyl isothiocyanate, a constituent of cruciferous vegetables, inhibits proliferation of human prostate cancer cells by causing G2/M arrest and inducing apoptosis Carcinogenesis 24 2003 891 897
28. S.R. Musk, and I.T. Johnson Allyl isothiocyanate is selectively toxic to transformed cells of the human colorectal tumour line HT29 Carcinogenesis 14 1993 2079 2083
29. L. Tang, and Y. Zhang Dietary isothiocyanates inhibit the growth of human bladder carcinoma cells J Nutr 134 2004 2004 2010
30. W.S. Jeong, I.W. Kim, R. Hu, and A.N. Kong Modulatory properties of various natural chemopreventive agents on the activation of NF-kappaB signaling pathway Pharm Res 21 2004 661 670
31. P. Thejass, and G. Kuttan Allyl isothiocyanate (AITC) and phenyl isothiocyanate (PITC) inhibit tumour-specific angiogenesis by downregulating nitric oxide (NO) and tumour necrosis factor-alpha (TNF-alpha) production Nitric Oxide 16 2007 247 257