-
1
-
-
0142166328
-
Cancer chemoprevention with dietary phytochemicals
-
Surh Y.J. Cancer chemoprevention with dietary phytochemicals. Nat Rev Cancer 3 (2003) 768-780
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 768-780
-
-
Surh, Y.J.1
-
2
-
-
0042130513
-
GUGULIPID: a natural cholesterol-lowering agent
-
Urizar N.L., and Moore D.D. GUGULIPID: a natural cholesterol-lowering agent. Annu Rev Nutr 23 (2003) 303-313
-
(2003)
Annu Rev Nutr
, vol.23
, pp. 303-313
-
-
Urizar, N.L.1
Moore, D.D.2
-
3
-
-
0036718907
-
Guggulsterone: an old approach to a new problem
-
Sinal C.J., and Gonzalez F.J. Guggulsterone: an old approach to a new problem. Trends Endocrinol Metab 13 (2002) 275-276
-
(2002)
Trends Endocrinol Metab
, vol.13
, pp. 275-276
-
-
Sinal, C.J.1
Gonzalez, F.J.2
-
4
-
-
0000527250
-
Antiarthritic and anti-inflammatory activity of gum guggul (Balsamodendron mukul Hook)
-
Gujral M.L., Sareen K., Tangri K.K., Amma M.K., and Roy A.K. Antiarthritic and anti-inflammatory activity of gum guggul (Balsamodendron mukul Hook). Indian J Physiol Pharmacol 4 (1960) 267-273
-
(1960)
Indian J Physiol Pharmacol
, vol.4
, pp. 267-273
-
-
Gujral, M.L.1
Sareen, K.2
Tangri, K.K.3
Amma, M.K.4
Roy, A.K.5
-
5
-
-
0017687334
-
Comparison of the anti-inflammatory activity of Commiphora mukul (an indigenous drug) with those of phenylbutazone and ibuprofen in experimental arthritis induced by mycobacterial adjuvant
-
Sharma J.N. Comparison of the anti-inflammatory activity of Commiphora mukul (an indigenous drug) with those of phenylbutazone and ibuprofen in experimental arthritis induced by mycobacterial adjuvant. Arzneimittelforschung 27 (1977) 1455-1457
-
(1977)
Arzneimittelforschung
, vol.27
, pp. 1455-1457
-
-
Sharma, J.N.1
-
6
-
-
0015349519
-
Anti-inflammatory studies on a crystalline steroid isolated from Commiphora mukul
-
Arora R.B., Taneja V., Sharma R.C., and Gupta S.K. Anti-inflammatory studies on a crystalline steroid isolated from Commiphora mukul. Indian J Med Res 60 (1972) 929-931
-
(1972)
Indian J Med Res
, vol.60
, pp. 929-931
-
-
Arora, R.B.1
Taneja, V.2
Sharma, R.C.3
Gupta, S.K.4
-
7
-
-
8744234076
-
Guggulsterone inhibits NF-kappaB and IkappaBalpha kinase activation, suppresses expression of anti-apoptotic gene products, and enhances apoptosis
-
Shishodia S., and Aggarwal B.B. Guggulsterone inhibits NF-kappaB and IkappaBalpha kinase activation, suppresses expression of anti-apoptotic gene products, and enhances apoptosis. J Biol Chem 279 (2004) 47148-47158
-
(2004)
J Biol Chem
, vol.279
, pp. 47148-47158
-
-
Shishodia, S.1
Aggarwal, B.B.2
-
8
-
-
31544446372
-
Guggulsterone inhibits osteoclastogenesis induced by receptor activator of nuclear factor-kappaB ligand and by tumor cells by suppressing nuclear factor-kappaB activation
-
Ichikawa H., and Aggarwal B.B. Guggulsterone inhibits osteoclastogenesis induced by receptor activator of nuclear factor-kappaB ligand and by tumor cells by suppressing nuclear factor-kappaB activation. Clin Cancer Res 12 (2006) 662-668
-
(2006)
Clin Cancer Res
, vol.12
, pp. 662-668
-
-
Ichikawa, H.1
Aggarwal, B.B.2
-
9
-
-
33751577977
-
Plant sterol guggulsterone inhibits nuclear factor-kappaB signaling in intestinal epithelial cells by blocking IkappaB kinase and ameliorates acute murine colitis
-
Cheon J.H., Kim J.S., Kim J.M., Kim N., Jung H.C., and Song I.S. Plant sterol guggulsterone inhibits nuclear factor-kappaB signaling in intestinal epithelial cells by blocking IkappaB kinase and ameliorates acute murine colitis. Inflamm Bowel Dis 12 (2006) 1152-1161
-
(2006)
Inflamm Bowel Dis
, vol.12
, pp. 1152-1161
-
-
Cheon, J.H.1
Kim, J.S.2
Kim, J.M.3
Kim, N.4
Jung, H.C.5
Song, I.S.6
-
10
-
-
0030831210
-
A human homologue of the Drosophila Toll protein signals activation of adaptive immunity
-
Medzhitov R., Preston-Hurlburt P., and Janeway Jr. C.A. A human homologue of the Drosophila Toll protein signals activation of adaptive immunity. Nature 388 (1997) 394-397
-
(1997)
Nature
, vol.388
, pp. 394-397
-
-
Medzhitov, R.1
Preston-Hurlburt, P.2
Janeway Jr., C.A.3
-
11
-
-
12444341944
-
Toll-like receptors in innate immunity
-
Takeda K., and Akira S. Toll-like receptors in innate immunity. Int Immunol 17 (2005) 1-14
-
(2005)
Int Immunol
, vol.17
, pp. 1-14
-
-
Takeda, K.1
Akira, S.2
-
12
-
-
33749152085
-
Toll-like receptors: from the discovery of NFkappaB to new insights into transcriptional regulations in innate immunity
-
Doyle S.L., and O'Neill L.A. Toll-like receptors: from the discovery of NFkappaB to new insights into transcriptional regulations in innate immunity. Biochem Pharmacol 72 (2006) 1102-1113
-
(2006)
Biochem Pharmacol
, vol.72
, pp. 1102-1113
-
-
Doyle, S.L.1
O'Neill, L.A.2
-
13
-
-
3142724031
-
Toll-like receptor signalling
-
Akira S., and Takeda K. Toll-like receptor signalling. Nat Rev Immunol 4 (2004) 499-511
-
(2004)
Nat Rev Immunol
, vol.4
, pp. 499-511
-
-
Akira, S.1
Takeda, K.2
-
14
-
-
0034602150
-
Murine TOLL-like receptor 4 confers lipopolysaccharide responsiveness as determined by activation of NF kappa B and expression of the inducible cyclooxygenase
-
Rhee S.H., and Hwang D. Murine TOLL-like receptor 4 confers lipopolysaccharide responsiveness as determined by activation of NF kappa B and expression of the inducible cyclooxygenase. J Biol Chem 275 (2000) 34035-34040
-
(2000)
J Biol Chem
, vol.275
, pp. 34035-34040
-
-
Rhee, S.H.1
Hwang, D.2
-
15
-
-
0031893220
-
Virus-dependent phosphorylation of the IRF-3 transcription factor regulates nuclear translocation, transactivation potential, and proteasome-mediated degradation
-
Lin R., Heylbroeck C., Pitha P.M., and Hiscott J. Virus-dependent phosphorylation of the IRF-3 transcription factor regulates nuclear translocation, transactivation potential, and proteasome-mediated degradation. Mol Cell Biol 18 (1998) 2986-2996
-
(1998)
Mol Cell Biol
, vol.18
, pp. 2986-2996
-
-
Lin, R.1
Heylbroeck, C.2
Pitha, P.M.3
Hiscott, J.4
-
16
-
-
0033544897
-
p38-dependent activation of interferon regulatory factor 3 by lipopolysaccharide
-
Navarro L., and David M. p38-dependent activation of interferon regulatory factor 3 by lipopolysaccharide. J Biol Chem 274 (1999) 35535-35538
-
(1999)
J Biol Chem
, vol.274
, pp. 35535-35538
-
-
Navarro, L.1
David, M.2
-
17
-
-
0038393016
-
IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway
-
Fitzgerald K.A., McWhirter S.M., Faia K.L., Rowe D.C., Latz E., Golenbock D.T., et al. IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway. Nat Immunol 4 (2003) 491-496
-
(2003)
Nat Immunol
, vol.4
, pp. 491-496
-
-
Fitzgerald, K.A.1
McWhirter, S.M.2
Faia, K.L.3
Rowe, D.C.4
Latz, E.5
Golenbock, D.T.6
-
18
-
-
0035889228
-
Lipopolysaccharide stimulates the MyD88-independent pathway and results in activation of IFN-regulatory factor 3 and the expression of a subset of lipopolysaccharide-inducible genes
-
Kawai T., Takeuchi O., Fujita T., Inoue J., Muhlradt P.F., Sato S., et al. Lipopolysaccharide stimulates the MyD88-independent pathway and results in activation of IFN-regulatory factor 3 and the expression of a subset of lipopolysaccharide-inducible genes. J Immunol 167 (2001) 5887-5894
-
(2001)
J Immunol
, vol.167
, pp. 5887-5894
-
-
Kawai, T.1
Takeuchi, O.2
Fujita, T.3
Inoue, J.4
Muhlradt, P.F.5
Sato, S.6
-
19
-
-
0001378811
-
Autocrine/paracrine IFN-alphabeta mediates the lipopolysaccharide-induced activation of transcription factor Stat1alpha in mouse macrophages: pivotal role of Stat1alpha in induction of the inducible nitric oxide synthase gene
-
Gao J.J., Filla M.B., Fultz M.J., Vogel S.N., Russell S.W., and Murphy W.J. Autocrine/paracrine IFN-alphabeta mediates the lipopolysaccharide-induced activation of transcription factor Stat1alpha in mouse macrophages: pivotal role of Stat1alpha in induction of the inducible nitric oxide synthase gene. J Immunol 161 (1998) 4803-4810
-
(1998)
J Immunol
, vol.161
, pp. 4803-4810
-
-
Gao, J.J.1
Filla, M.B.2
Fultz, M.J.3
Vogel, S.N.4
Russell, S.W.5
Murphy, W.J.6
-
20
-
-
33744526702
-
Inhibition of homodimerization of Toll-like receptor 4 by curcumin
-
Youn H.S., Saitoh S.I., Miyake K., and Hwang D.H. Inhibition of homodimerization of Toll-like receptor 4 by curcumin. Biochem Pharmacol 72 (2006) 62-69
-
(2006)
Biochem Pharmacol
, vol.72
, pp. 62-69
-
-
Youn, H.S.1
Saitoh, S.I.2
Miyake, K.3
Hwang, D.H.4
-
21
-
-
33748189399
-
Suppression of MyD88- and TRIF-dependent signaling pathways of Toll-like receptor by (-)-epigallocatechin-3-gallate, a polyphenol component of green tea
-
Youn H.S., Lee J.Y., Saitoh S.I., Miyake K., Kang K.W., Choi Y.J., et al. Suppression of MyD88- and TRIF-dependent signaling pathways of Toll-like receptor by (-)-epigallocatechin-3-gallate, a polyphenol component of green tea. Biochem Pharmacol 72 (2006) 850-859
-
(2006)
Biochem Pharmacol
, vol.72
, pp. 850-859
-
-
Youn, H.S.1
Lee, J.Y.2
Saitoh, S.I.3
Miyake, K.4
Kang, K.W.5
Choi, Y.J.6
-
22
-
-
23844478190
-
Specific inhibition of MyD88-independent signaling pathways of TLR3 and TLR4 by resveratrol: molecular targets are TBK1 and RIP1 in TRIF complex
-
Youn H.S., Lee J.Y., Fitzgerald K.A., Young H.A., Akira S., and Hwang D.H. Specific inhibition of MyD88-independent signaling pathways of TLR3 and TLR4 by resveratrol: molecular targets are TBK1 and RIP1 in TRIF complex. J Immunol 175 (2005) 3339-3346
-
(2005)
J Immunol
, vol.175
, pp. 3339-3346
-
-
Youn, H.S.1
Lee, J.Y.2
Fitzgerald, K.A.3
Young, H.A.4
Akira, S.5
Hwang, D.H.6
-
23
-
-
36049033394
-
Signaling to NF-kappaB by Toll-like receptors
-
Kawai T., and Akira S. Signaling to NF-kappaB by Toll-like receptors. Trends Mol Med 13 (2007) 460-469
-
(2007)
Trends Mol Med
, vol.13
, pp. 460-469
-
-
Kawai, T.1
Akira, S.2
-
24
-
-
0030613551
-
The IkappaB kinase complex (IKK) contains two kinase subunits, IKKalpha and IKKbeta, necessary for IkappaB phosphorylation and NF-kappaB activation
-
Zandi E., Rothwarf D.M., Delhase M., Hayakawa M., and Karin M. The IkappaB kinase complex (IKK) contains two kinase subunits, IKKalpha and IKKbeta, necessary for IkappaB phosphorylation and NF-kappaB activation. Cell 91 (1997) 243-252
-
(1997)
Cell
, vol.91
, pp. 243-252
-
-
Zandi, E.1
Rothwarf, D.M.2
Delhase, M.3
Hayakawa, M.4
Karin, M.5
-
25
-
-
0032568792
-
Complementation cloning of NEMO, a component of the IkappaB kinase complex essential for NF-kappaB activation
-
Yamaoka S., Courtois G., Bessia C., Whiteside S.T., Weil R., Agou F., et al. Complementation cloning of NEMO, a component of the IkappaB kinase complex essential for NF-kappaB activation. Cell 93 (1998) 1231-1240
-
(1998)
Cell
, vol.93
, pp. 1231-1240
-
-
Yamaoka, S.1
Courtois, G.2
Bessia, C.3
Whiteside, S.T.4
Weil, R.5
Agou, F.6
-
26
-
-
0032926882
-
Essential role of interferon regulatory factor 3 in direct activation of RANTES chemokine transcription
-
Lin R., Heylbroeck C., Genin P., Pitha P.M., and Hiscott J. Essential role of interferon regulatory factor 3 in direct activation of RANTES chemokine transcription. Mol Cell Biol 19 (1999) 959-966
-
(1999)
Mol Cell Biol
, vol.19
, pp. 959-966
-
-
Lin, R.1
Heylbroeck, C.2
Genin, P.3
Pitha, P.M.4
Hiscott, J.5
-
27
-
-
0032579369
-
Regulation of type I interferon gene expression by interferon regulatory factor-3
-
Schafer S.L., Lin R., Moore P.A., Hiscott J., and Pitha P.M. Regulation of type I interferon gene expression by interferon regulatory factor-3. J Biol Chem 273 (1998) 2714-2720
-
(1998)
J Biol Chem
, vol.273
, pp. 2714-2720
-
-
Schafer, S.L.1
Lin, R.2
Moore, P.A.3
Hiscott, J.4
Pitha, P.M.5
-
28
-
-
33748455338
-
Type I interferons in host defense
-
Stetson D.B., and Medzhitov R. Type I interferons in host defense. Immunity 25 (2006) 373-381
-
(2006)
Immunity
, vol.25
, pp. 373-381
-
-
Stetson, D.B.1
Medzhitov, R.2
-
29
-
-
34848820013
-
Diversity and regulation in the NF-kappaB system
-
Wietek C., and O'Neill L.A. Diversity and regulation in the NF-kappaB system. Trends Biochem Sci 32 (2007) 311-319
-
(2007)
Trends Biochem Sci
, vol.32
, pp. 311-319
-
-
Wietek, C.1
O'Neill, L.A.2
-
30
-
-
33748051738
-
IRFs: master regulators of signalling by Toll-like receptors and cytosolic pattern-recognition receptors
-
Honda K., and Taniguchi T. IRFs: master regulators of signalling by Toll-like receptors and cytosolic pattern-recognition receptors. Nat Rev Immunol 6 (2006) 644-658
-
(2006)
Nat Rev Immunol
, vol.6
, pp. 644-658
-
-
Honda, K.1
Taniguchi, T.2
-
31
-
-
0035951457
-
A new family of IKK-related kinases may function as I kappa B kinase kinases
-
Peters R.T., and Maniatis T. A new family of IKK-related kinases may function as I kappa B kinase kinases. Biochim Biophys Acta 1471 (2001) M57-62
-
(2001)
Biochim Biophys Acta
, vol.1471
-
-
Peters, R.T.1
Maniatis, T.2
-
32
-
-
0032808084
-
IKK-i, a novel lipopolysaccharide-inducible kinase that is related to IkappaB kinases
-
Shimada T., Kawai T., Takeda K., Matsumoto M., Inoue J., Tatsumi Y., et al. IKK-i, a novel lipopolysaccharide-inducible kinase that is related to IkappaB kinases. Int Immunol 11 (1999) 1357-1362
-
(1999)
Int Immunol
, vol.11
, pp. 1357-1362
-
-
Shimada, T.1
Kawai, T.2
Takeda, K.3
Matsumoto, M.4
Inoue, J.5
Tatsumi, Y.6
-
33
-
-
0035950978
-
Expression and regulation of inducible IkappaB kinase (IKK-i) in human fibroblast-like synoviocytes
-
Aupperle K.R., Yamanishi Y., Bennett B.L., Mercurio F., Boyle D.L., and Firestein G.S. Expression and regulation of inducible IkappaB kinase (IKK-i) in human fibroblast-like synoviocytes. Cell Immunol 214 (2001) 54-59
-
(2001)
Cell Immunol
, vol.214
, pp. 54-59
-
-
Aupperle, K.R.1
Yamanishi, Y.2
Bennett, B.L.3
Mercurio, F.4
Boyle, D.L.5
Firestein, G.S.6
-
34
-
-
4344566281
-
The roles of two IkappaB kinase-related kinases in lipopolysaccharide and double stranded RNA signaling and viral infection
-
Hemmi H., Takeuchi O., Sato S., Yamamoto M., Kaisho T., Sanjo H., et al. The roles of two IkappaB kinase-related kinases in lipopolysaccharide and double stranded RNA signaling and viral infection. J Exp Med 199 (2004) 1641-1650
-
(2004)
J Exp Med
, vol.199
, pp. 1641-1650
-
-
Hemmi, H.1
Takeuchi, O.2
Sato, S.3
Yamamoto, M.4
Kaisho, T.5
Sanjo, H.6
-
35
-
-
0345827590
-
IFN-regulatory factor 3-dependent gene expression is defective in Tbk1-deficient mouse embryonic fibroblasts
-
McWhirter S.M., Fitzgerald K.A., Rosains J., Rowe D.C., Golenbock D.T., and Maniatis T. IFN-regulatory factor 3-dependent gene expression is defective in Tbk1-deficient mouse embryonic fibroblasts. Proc Natl Acad Sci U S A 101 (2004) 233-238
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 233-238
-
-
McWhirter, S.M.1
Fitzgerald, K.A.2
Rosains, J.3
Rowe, D.C.4
Golenbock, D.T.5
Maniatis, T.6
-
36
-
-
3042647375
-
Differential requirement for TANK-binding kinase-1 in type I interferon responses to toll-like receptor activation and viral infection
-
Perry A.K., Chow E.K., Goodnough J.B., Yeh W.C., and Cheng G. Differential requirement for TANK-binding kinase-1 in type I interferon responses to toll-like receptor activation and viral infection. J Exp Med 199 (2004) 1651-1658
-
(2004)
J Exp Med
, vol.199
, pp. 1651-1658
-
-
Perry, A.K.1
Chow, E.K.2
Goodnough, J.B.3
Yeh, W.C.4
Cheng, G.5
-
37
-
-
19944362471
-
The induction of macrophage gene expression by LPS predominantly utilizes Myd88-independent signaling cascades
-
Bjorkbacka H., Fitzgerald K.A., Huet F., Li X., Gregory J.A., Lee M.A., et al. The induction of macrophage gene expression by LPS predominantly utilizes Myd88-independent signaling cascades. Physiol Genomics 19 (2004) 319-330
-
(2004)
Physiol Genomics
, vol.19
, pp. 319-330
-
-
Bjorkbacka, H.1
Fitzgerald, K.A.2
Huet, F.3
Li, X.4
Gregory, J.A.5
Lee, M.A.6
-
38
-
-
0037205046
-
A natural product that lowers cholesterol as an antagonist ligand for FXR
-
Urizar N.L., Liverman A.B., Dodds D.T., Silva F.V., Ordentlich P., Yan Y., et al. A natural product that lowers cholesterol as an antagonist ligand for FXR. Science 296 (2002) 1703-1706
-
(2002)
Science
, vol.296
, pp. 1703-1706
-
-
Urizar, N.L.1
Liverman, A.B.2
Dodds, D.T.3
Silva, F.V.4
Ordentlich, P.5
Yan, Y.6
-
39
-
-
0003295132
-
Guggulsterone is a farnesoid X receptor antagonist in coactivator association assays but acts to enhance transcription of bile salt export pump
-
Cui J., Huang L., Zhao A., Lew J.L., Yu J., Sahoo S., et al. Guggulsterone is a farnesoid X receptor antagonist in coactivator association assays but acts to enhance transcription of bile salt export pump. J Biol Chem 278 (2003) 10214-10220
-
(2003)
J Biol Chem
, vol.278
, pp. 10214-10220
-
-
Cui, J.1
Huang, L.2
Zhao, A.3
Lew, J.L.4
Yu, J.5
Sahoo, S.6
-
40
-
-
31544446372
-
Guggulsterone inhibits osteoclastogenesis induced by receptor activator of nuclear factor-kappaB ligand and by tumor cells by suppressing nuclear factor-kappaB activation
-
Ichikawa H., and Aggarwal B.B. Guggulsterone inhibits osteoclastogenesis induced by receptor activator of nuclear factor-kappaB ligand and by tumor cells by suppressing nuclear factor-kappaB activation. Clin Cancer Res 12 (2006) 662-668
-
(2006)
Clin Cancer Res
, vol.12
, pp. 662-668
-
-
Ichikawa, H.1
Aggarwal, B.B.2
|