Constrained solution scattering modelling of human antibodies and complement proteins reveals novel biological insights

Journal of the Royal Society Interface

Volumn 6, Issue SUPPL. 5, 2009, Pages

  Perkins, Stephen J ^a   Okemefuna, Azubuike I ^a   Nan, Ruodan ^a   Li, Keying ^a   Bonner, Alexandra ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Analytical ultracentrifugation; Complement factor H; Constrained modelling; Immunoglobulin A; Neutron scattering; X ray scattering

Indexed keywords

CENTRIFUGATION; CRYSTAL STRUCTURE; NEUTRON DIFFRACTION; NEUTRON SCATTERING; NEUTRONS; X RAY SCATTERING;

AGE-RELATED MACULAR DEGENERATION; ANALYTICAL ULTRACENTRIFUGATION; BEST-FIT MODELS; BIOLOGICAL FUNCTIONS; BIOLOGICAL INSIGHT; COMPLEMENT FACTOR H; COMPLEMENT STRUCTURE; COMPLEMENT SYSTEMS; COMPLEMENTARY DATA; CONSTRAINED MODELLING; EXPERIMENTAL DATA; HIGH RESOLUTION; HUMAN ANTIBODIES; HUMAN BODIES; IMMUNOGLOBULIN A; MODELLING METHOD; MUCOSAL IMMUNITY; MULTI DOMAINS; PROTEIN-PROTEIN COMPLEXES; RENAL DISEASE; SOLUTION STRUCTURES; STRUCTURAL STUDIES; STRUCTURE DETERMINATION;

ANTIBODIES;

ANTIBODY; COMPLEMENT FACTOR H; IMMUNOGLOBULIN A;

ALGORITHM; COMPLEMENT SYSTEM; CONFERENCE PAPER; CRYSTAL STRUCTURE; CRYSTALLIZATION; EXPERIMENTAL STUDY; HUMAN; IMMUNITY; KIDNEY DISEASE; MUCOSAL IMMUNITY; NEUTRON SCATTERING; NONHUMAN; PROTEIN ANALYSIS; PROTEIN CONFORMATION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; RADIATION SCATTERING; RETINA MACULA AGE RELATED DEGENERATION; SIMULATION; ULTRACENTRIFUGATION; X RAY ANALYSIS;

ANTIBODIES; COMPLEMENT SYSTEM PROTEINS; COMPUTER SIMULATION; MODELS, CHEMICAL; MODELS, MOLECULAR; MULTIPROTEIN COMPLEXES; NEUTRON DIFFRACTION; X-RAY DIFFRACTION;

EID: 69949145065     PISSN: 17425689     EISSN: 17425662     Source Type: Journal    
DOI: 10.1098/rsif.2009.0164.focus     Document Type: Conference Paper

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